Research Topics
| Sergi G CostafredaSummaryAffiliation: King's College London Country: UK Publications
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Detail Information
Publications
Parametric coordinate-based meta-analysis: valid effect size meta-analysis of studies with differing statistical thresholdsSergi G Costafreda
Department of Old Age Psychiatry, Institute of Psychiatry, King s College London, Box PO 070, De Crespigny Park, SE5 8AF London, UK
J Neurosci Methods 210:291-300. 2012....
Pattern of neural responses to verbal fluency shows diagnostic specificity for schizophrenia and bipolar disorderSergi G Costafreda
Institute of Psychiatry, King s College London, De Crespigny Park, London UK
BMC Psychiatry 11:18. 2011..Determining the distinct pattern of neural responses in schizophrenia and bipolar disorder may provide biomarkers for their diagnoses...- Automated hippocampal shape analysis predicts the onset of dementia in mild cognitive impairmentSergi G Costafreda
King s College London, London, UK
Neuroimage 56:212-9. 2011..We conclude that automated shape analysis generates sensitive measurements of early neurodegeneration which predates the onset of dementia and thus provides a prognostic biomarker for conversion of MCI to AD... - Increased inferior frontal activation during word generation: a marker of genetic risk for schizophrenia but not bipolar disorder?Sergi G Costafreda
Institute of Psychiatry, King s College London, London, United Kingdom
Hum Brain Mapp 30:3287-98. 2009..Increased engagement of the inferior frontal cortex during verbal-fluency may thus be a marker of genetic vulnerability to schizophrenia... - Neural correlates of sad faces predict clinical remission to cognitive behavioural therapy in depressionSergi G Costafreda
Institute of Psychiatry, King s College London, De Crespigny Park, London, UK
Neuroreport 20:637-41. 2009..The functional neuroanatomy of sad faces at the lowest and highest intensities identified patients, before the initiation of therapy, who had a full clinical response to CBT (sensitivity 71%, specificity 86%, P = 0.029)... - Hippocampal atrophy in first episode depression: a meta-analysis of magnetic resonance imaging studiesJames Cole
Institute of Psychiatry, King s College London, London, UK
J Affect Disord 134:483-7. 2011..Hippocampal volume loss is particularly evident in patients with recurrent and chronic depression. However, the reports in first episode depression have been mixed... - Machine learning classification with confidence: application of transductive conformal predictors to MRI-based diagnostic and prognostic markers in depressionIlia Nouretdinov
Institute of Psychiatry, King s College London, London, UK
Neuroimage 56:809-13. 2011..We verify that TCP predictions are as accurate as those obtained with more standard machine learning methods, such as support vector machine, while providing the additional benefit of a valid measure of confidence for each prediction... - A parametric approach to voxel-based meta-analysisSergi G Costafreda
Institute of Psychiatry, King s College London, UK
Neuroimage 46:115-22. 2009..We illustrate the technique by performing a random-effects meta-analysis of word production. Parametric voxel-based meta-analysis provides a powerful and practical tool for neuroimaging meta-analysis... 
Predictors of amygdala activation during the processing of emotional stimuli: a meta-analysis of 385 PET and fMRI studiesSergi G Costafreda
Institute of Psychiatry, King s College London, UK
Brain Res Rev 58:57-70. 2008..Methodological variables, such as type of analysis and magnet strength, were also independent predictors of amygdala activation...- A systematic review and quantitative appraisal of fMRI studies of verbal fluency: role of the left inferior frontal gyrusSergi G Costafreda
Brain Image Analysis Unit, Department of Biostatistics and Computing, Institute of Psychiatry, King s College London, London, United Kingdom
Hum Brain Mapp 27:799-810. 2006..The results support distinct dorsal-ventral locations for phonologic and semantic processes within the LIFG. Current limitations to meta-analytic integration of published functional neuroimaging studies are discussed... - Subregional hippocampal deformations in major depressive disorderJames Cole
Institute of Psychiatry, King s College London, De Crespigny Park, London, UK
J Affect Disord 126:272-7. 2010..The present study sought to examine hippocampal volume and subregional morphology in patients with major depressive disorder, who were all medication-free and in an acute depressive episode of moderate severity... - Pattern classification of sad facial processing: toward the development of neurobiological markers in depressionCynthia H Y Fu
Institute of Psychiatry, King s College London, De Crespigny Park, London, United Kingdom
Biol Psychiatry 63:656-62. 2008..We sought to examine the sensitivity and specificity of whole brain pattern classification of implicit processing of sad facial expressions in depression... - Multisite fMRI reproducibility of a motor task using identical MR systemsSergi G Costafreda
Brain Image Analysis Unit, Institute of Psychiatry, King s College London, UK
J Magn Reson Imaging 26:1122-6. 2007..To estimate between-scanner functional MRI (fMRI) reproducibility in a multisite study... - Bayesian wavelet-based analysis of functional magnetic resonance time seriesSergi G Costafreda
Brain Image Analysis Unit, Department of Biostatistics and Computing, Institute of Psychiatry, King s College, DeCrespigny Park, London, UK
Magn Reson Imaging 27:460-9. 2009..Through testing on a combination of simulated and real fMRI data, we show evidence of improved signal recovery, without compromising test accuracy in image space... - Effects of ketamine on prefrontal and striatal regions in an overt verbal fluency task: a functional magnetic resonance imaging studyCynthia H Y Fu
Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
Psychopharmacology (Berl) 183:92-102. 2005..Glutamatergic dysfunction at N-methyl-D: -aspartate (NMDA) receptors has been proposed as a neurochemical model for schizophrenia. A key feature of this disorder is impairments in cognitive function... - Predictive neural biomarkers of clinical response in depression: a meta-analysis of functional and structural neuroimaging studies of pharmacological and psychological therapiesCynthia H Y Fu
Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
Neurobiol Dis 52:75-83. 2013..We propose that structural and functional neuroimaging show significant potential for the development of prognostic markers of clinical response in the treatment of depression... - Prognostic and diagnostic potential of the structural neuroanatomy of depressionSergi G Costafreda
Institute of Psychiatry, King s College London, London, UK
PLoS ONE 4:e6353. 2009..In the present study, we examined the prognostic and diagnostic potential of the structural neural correlates of depression...