C Corrigan

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi Methotrexate therapy in asthma increases T cell susceptibility to corticosteroid inhibition
    C J Corrigan
    Guy s, King s and St Thomas Imperial College Schools of Medicine, London, UK
    Clin Exp Allergy 33:1090-6. 2003
  2. ncbi Methotrexate therapy of oral corticosteroid-dependent asthmatics reduces serum immunoglobulins: correlation with clinical response to therapy
    C J Corrigan
    Guy s, King s and St Thomas, London, UK
    Clin Exp Allergy 35:579-84. 2005
  3. ncbi The eotaxins in asthma and allergic inflammation: implications for therapy
    C Corrigan
    Department of Respiratory, Medicine and Allergy, Guy s, King s and St Thomas School of Medicine, 5th Floor Thomas Guy House, Guy s Hospital, London, SE1 9RT, UK
    Curr Opin Investig Drugs 1:321-8. 2000
  4. ncbi The ADMIT series--issues in inhalation therapy. 3) Mild persistent asthma: the case for inhaled corticosteroid therapy
    Chris J Corrigan
    Department of Asthma, Allergy and Respiratory Science, King s College London School of Medicine, London, UK
    Prim Care Respir J 18:148-58. 2009
  5. ncbi Expression of the cysteinyl leukotriene receptors cysLT(1) and cysLT(2) in aspirin-sensitive and aspirin-tolerant chronic rhinosinusitis
    Chris Corrigan
    Department of Asthma, Allergy and Respiratory Science, Guy s Hospital, London, UK
    J Allergy Clin Immunol 115:316-22. 2005
  6. ncbi Mechanisms of intrinsic asthma
    Chris Corrigan
    Guy s, King s and St Thomas School of Medicine, King s College, London, UK
    Curr Opin Allergy Clin Immunol 4:53-6. 2004
  7. ncbi Asthma refractory to glucocorticoids: the role of newer immunosuppressants
    Chris J Corrigan
    Department of Respiratory Medicine and Allergy, Guy s, King s and St Thomas School of Medicine, Thomas Guy House, Guy s Hospital, London SE1 9RT, UK
    Am J Respir Med 1:47-54. 2002
  8. ncbi Counter regulation of the high affinity IgE receptor, FcepsilonRI, on human airway dendritic cells by IL-4 and IL-10
    A Faith
    MRC Asthma UK Centre in Allergic Mechanisms of Asthma, King s College, London, UK
    Allergy 64:1602-7. 2009
  9. ncbi Role of cysteinyl leukotrienes in human allergen-specific Th2 responses induced by granulocyte macrophage-colony stimulating factor
    A Faith
    Asthma UK and MRC, Centre in Allergic Mechanisms of Asthma, King s College London, and Department of Asthma, Allergy and Respiratory Science, Guy s Hospital, London, UK
    Allergy 63:168-75. 2008
  10. ncbi Efficacy and safety of preseasonal-specific immunotherapy with an aluminium-adsorbed six-grass pollen allergoid
    C J Corrigan
    Guy's, King's and St Thomas's School of Medicine, London, UK
    Allergy 60:801-7. 2005

Detail Information

Publications16

  1. ncbi Methotrexate therapy in asthma increases T cell susceptibility to corticosteroid inhibition
    C J Corrigan
    Guy s, King s and St Thomas Imperial College Schools of Medicine, London, UK
    Clin Exp Allergy 33:1090-6. 2003
    ..We hypothesized that MTX therapy of these patients increases the susceptibility of their T cells to corticosteroid inhibition...
  2. ncbi Methotrexate therapy of oral corticosteroid-dependent asthmatics reduces serum immunoglobulins: correlation with clinical response to therapy
    C J Corrigan
    Guy s, King s and St Thomas, London, UK
    Clin Exp Allergy 35:579-84. 2005
    ..In a previous report, we showed that MTX increases T cell inhibition by CS. In this report we focus on effects of MTX on immunoglobulin concentrations and their possible clinical relevance...
  3. ncbi The eotaxins in asthma and allergic inflammation: implications for therapy
    C Corrigan
    Department of Respiratory, Medicine and Allergy, Guy s, King s and St Thomas School of Medicine, 5th Floor Thomas Guy House, Guy s Hospital, London, SE1 9RT, UK
    Curr Opin Investig Drugs 1:321-8. 2000
    ..This article reviews the evidence for this involvement and describes new approaches to therapeutics that are evolving as a result...
  4. ncbi The ADMIT series--issues in inhalation therapy. 3) Mild persistent asthma: the case for inhaled corticosteroid therapy
    Chris J Corrigan
    Department of Asthma, Allergy and Respiratory Science, King s College London School of Medicine, London, UK
    Prim Care Respir J 18:148-58. 2009
    ..ICS has variable effects on features of airways remodelling but the long term physiological consequences of these effects, if any, are as yet unknown...
  5. ncbi Expression of the cysteinyl leukotriene receptors cysLT(1) and cysLT(2) in aspirin-sensitive and aspirin-tolerant chronic rhinosinusitis
    Chris Corrigan
    Department of Asthma, Allergy and Respiratory Science, Guy s Hospital, London, UK
    J Allergy Clin Immunol 115:316-22. 2005
    ..We previously compared expression of cysLT 1 on mucosal leukocytes in patients with aspirin-sensitive and aspirin-tolerant rhinosinusitis...
  6. ncbi Mechanisms of intrinsic asthma
    Chris Corrigan
    Guy s, King s and St Thomas School of Medicine, King s College, London, UK
    Curr Opin Allergy Clin Immunol 4:53-6. 2004
    ..With the current availability of anti-IgE therapy for asthma, clarification of this issue has never been more timely and relevant...
  7. ncbi Asthma refractory to glucocorticoids: the role of newer immunosuppressants
    Chris J Corrigan
    Department of Respiratory Medicine and Allergy, Guy s, King s and St Thomas School of Medicine, Thomas Guy House, Guy s Hospital, London SE1 9RT, UK
    Am J Respir Med 1:47-54. 2002
    ....
  8. ncbi Counter regulation of the high affinity IgE receptor, FcepsilonRI, on human airway dendritic cells by IL-4 and IL-10
    A Faith
    MRC Asthma UK Centre in Allergic Mechanisms of Asthma, King s College, London, UK
    Allergy 64:1602-7. 2009
    ..Little is known, however, of the expression and function of FcepsilonRI on DC in the human respiratory tract...
  9. ncbi Role of cysteinyl leukotrienes in human allergen-specific Th2 responses induced by granulocyte macrophage-colony stimulating factor
    A Faith
    Asthma UK and MRC, Centre in Allergic Mechanisms of Asthma, King s College London, and Department of Asthma, Allergy and Respiratory Science, Guy s Hospital, London, UK
    Allergy 63:168-75. 2008
    ..We hypothesized that exposure of AM and monocytes from atopic asthmatic patients to GM-CSF would enhance their antigen presenting function, and investigated putative mechanisms for this effect...
  10. ncbi Efficacy and safety of preseasonal-specific immunotherapy with an aluminium-adsorbed six-grass pollen allergoid
    C J Corrigan
    Guy's, King's and St Thomas's School of Medicine, London, UK
    Allergy 60:801-7. 2005
    ..The allergoid was well tolerated. CONCLUSIONS: The grass pollen allergoid was shown to be safe and clinically efficacious in the management of hay fever with or without asthma (GINA I or II)...
  11. ncbi Expression and cellular provenance of thymic stromal lymphopoietin and chemokines in patients with severe asthma and chronic obstructive pulmonary disease
    Sun Ying
    King s College London, Division of Asthma, Allergy and Lung Biology, Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom
    J Immunol 181:2790-8. 2008
    ..Increased expression of these chemokines is not, however, associated with selective accumulation of T cells bearing their receptors...
  12. ncbi IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells
    Yui Hsi Wang
    Department of Immunology and Center of Cancer Immunology Research, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Exp Med 204:1837-47. 2007
    ..Our results provide a plausible explanation that IL-25 produced by innate effector eosinophils and basophils may augment the allergic inflammation by enhancing the maintenance and functions of adaptive Th2 memory cells...
  13. ncbi Lack of filaggrin expression in the human bronchial mucosa
    Sun Ying
    J Allergy Clin Immunol 118:1386-8. 2006
  14. ncbi Systemic glucocorticoid reduces bronchial mucosal activation of activator protein 1 components in glucocorticoid-sensitive but not glucocorticoid-resistant asthmatic patients
    Tuck-Kay Loke
    King's College London, MRC, London SE1 9RT
    J Allergy Clin Immunol 118:368-75. 2006
    ..CLINICAL IMPLICATIONS: Dysregulation of activator protein 1 activation leading to clinical GC resistance might reflect identifiable environmental influences and is a target for future therapy...
  15. ncbi Expression of activation markers and cytokine mRNA by peripheral blood CD4 and CD8 T cells in atopic and nonatopic childhood asthma: effect of inhaled glucocorticoid therapy
    Vasso Gemou-Engesaeth
    Department of Pediatrics, Ulleval University Hospital, Oslo, Norway
    Pediatrics 109:E24. 2002
    ..Activated CD8 as well as CD4 T cells contribute to the production of asthma-relevant cytokines in both atopic and nonatopic childhood asthma...
  16. ncbi Aspirin-sensitive rhinosinusitis is associated with reduced E-prostanoid 2 receptor expression on nasal mucosal inflammatory cells
    Sun Ying
    King s College London, MRC and Asthma UK Centre, Department of Asthma, Allergy and Respiratory Science, UK
    J Allergy Clin Immunol 117:312-8. 2006
    ..PGE(2) acts via G-protein-coupled receptors, E-prostanoid (EP)(1-4,) but there is little information on the expression of PGE(2) receptors in this condition...