Sarah Cohen-Woods

Summary

Affiliation: King's College London
Country: UK

Publications

  1. pmc Methylenetetrahydrofolate reductase gene variant (MTHFR C677T) and migraine: a case control study and meta-analysis
    Zainab Samaan
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada
    BMC Neurol 11:66. 2011
  2. ncbi request reprint Depression Case Control (DeCC) Study fails to support involvement of the muscarinic acetylcholine receptor M2 (CHRM2) gene in recurrent major depressive disorder
    Sarah Cohen-Woods
    MRC SGDP Centre, Institute of Psychiatry, King s College London, London, UK
    Hum Mol Genet 18:1504-9. 2009
  3. pmc Interaction between specific forms of childhood maltreatment and the serotonin transporter gene (5-HTT) in recurrent depressive disorder
    Helen L Fisher
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, Box P080, De Crespigny Park, London SE5 8AF, UK
    J Affect Disord 145:136-41. 2013
  4. doi request reprint The interaction between child maltreatment, adult stressful life events and the 5-HTTLPR in major depression
    Robert A Power
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
    J Psychiatr Res 47:1032-5. 2013
  5. doi request reprint Dissecting the genetic heterogeneity of depression through age at onset
    Robert A Power
    MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 159:859-68. 2012
  6. doi request reprint Genome-wide association analysis accounting for environmental factors through propensity-score matching: application to stressful live events in major depressive disorder
    Robert A Power
    MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 162:521-9. 2013
  7. doi request reprint Convergent animal and human evidence suggests a role of PPM1A gene in response to antidepressants
    Karim Malki
    Institute of Psychiatry, King s College London, United Kingdom
    Biol Psychiatry 69:360-5. 2011
  8. doi request reprint The Bipolar Association Case-Control Study (BACCS) and meta-analysis: No association with the 5,10-Methylenetetrahydrofolate reductase gene and bipolar disorder
    Sarah Cohen-Woods
    Institute of Psychiatry, King s College London, MRC SGDP Centre, London, UK
    Am J Med Genet B Neuropsychiatr Genet 153:1298-304. 2010
  9. ncbi request reprint Genome-wide association study of major recurrent depression in the U.K. population
    Cathryn M Lewis
    Medical Research Council s Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, De Crespigny Park, London, United Kingdom
    Am J Psychiatry 167:949-57. 2010
  10. pmc Genomewide association scan of suicidal thoughts and behaviour in major depression
    Alexandra Schosser
    MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    PLoS ONE 6:e20690. 2011

Collaborators

Detail Information

Publications21

  1. pmc Methylenetetrahydrofolate reductase gene variant (MTHFR C677T) and migraine: a case control study and meta-analysis
    Zainab Samaan
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada
    BMC Neurol 11:66. 2011
    ..We aim to investigate the effect of this variant on propensity for migraine and to perform a systematic review and meta-analysis of studies of MTHFR and migraine to date...
  2. ncbi request reprint Depression Case Control (DeCC) Study fails to support involvement of the muscarinic acetylcholine receptor M2 (CHRM2) gene in recurrent major depressive disorder
    Sarah Cohen-Woods
    MRC SGDP Centre, Institute of Psychiatry, King s College London, London, UK
    Hum Mol Genet 18:1504-9. 2009
    ..It is possible our failure to replicate may be a consequence of differences in definition of the MDD phenotype and/or ethnic differences...
  3. pmc Interaction between specific forms of childhood maltreatment and the serotonin transporter gene (5-HTT) in recurrent depressive disorder
    Helen L Fisher
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, Box P080, De Crespigny Park, London SE5 8AF, UK
    J Affect Disord 145:136-41. 2013
    ....
  4. doi request reprint The interaction between child maltreatment, adult stressful life events and the 5-HTTLPR in major depression
    Robert A Power
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
    J Psychiatr Res 47:1032-5. 2013
    ....
  5. doi request reprint Dissecting the genetic heterogeneity of depression through age at onset
    Robert A Power
    MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 159:859-68. 2012
    ..04). This study provides the first focussed analysis of the genetic contribution to AAO in depression, and establishes a statistical framework that can be applied to a quantitative trait underlying any disorder...
  6. doi request reprint Genome-wide association analysis accounting for environmental factors through propensity-score matching: application to stressful live events in major depressive disorder
    Robert A Power
    MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 162:521-9. 2013
    ....
  7. doi request reprint Convergent animal and human evidence suggests a role of PPM1A gene in response to antidepressants
    Karim Malki
    Institute of Psychiatry, King s College London, United Kingdom
    Biol Psychiatry 69:360-5. 2011
    ..We report on an integrative analysis from the Genome-Based Therapeutic Drugs for Depression (GENDEP) study using gene expression from mice to inform prioritization in a human pharmacogenetic study...
  8. doi request reprint The Bipolar Association Case-Control Study (BACCS) and meta-analysis: No association with the 5,10-Methylenetetrahydrofolate reductase gene and bipolar disorder
    Sarah Cohen-Woods
    Institute of Psychiatry, King s College London, MRC SGDP Centre, London, UK
    Am J Med Genet B Neuropsychiatr Genet 153:1298-304. 2010
    ..We also performed a meta-analysis of our own, and all published data, and report no evidence for association. Our findings suggest that the MTHFR C677T polymorphism is not involved in the genetic etiology of clinically significant BD...
  9. ncbi request reprint Genome-wide association study of major recurrent depression in the U.K. population
    Cathryn M Lewis
    Medical Research Council s Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, De Crespigny Park, London, United Kingdom
    Am J Psychiatry 167:949-57. 2010
    ..K. and 1,594 comparison subjects screened negative for psychiatric disorders...
  10. pmc Genomewide association scan of suicidal thoughts and behaviour in major depression
    Alexandra Schosser
    MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    PLoS ONE 6:e20690. 2011
    ..Suicidal behaviour can be conceptualised as a continuum from suicidal ideation, to suicidal attempts to completed suicide. In this study we identify genes contributing to suicidal behaviour in the depression study RADIANT...
  11. ncbi request reprint Genome-wide association study of co-occurring anxiety in major depression
    Alexandra Schosser
    MRC SGDP Centre, Institute of Psychiatry, King s College London, London, UK
    World J Biol Psychiatry 14:611-21. 2013
    ..In this study we define a quantitative measure of anxiety by summating four anxiety items from the SCAN interview in a large collection of major depression (MDD) cases to identify genes contributing to this complex phenotype...
  12. pmc Stressful life events and the serotonin transporter gene (5-HTT) in recurrent clinical depression
    Helen L Fisher
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
    J Affect Disord 136:189-93. 2012
    ....
  13. doi request reprint A genome-wide significant linkage for severe depression on chromosome 3: the depression network study
    Gerome Breen
    Medical Research Council Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London
    Am J Psychiatry 168:840-7. 2011
    ..The purpose of this study was to find loci for major depression via linkage analysis of a large sibling pair sample...
  14. ncbi request reprint Stressful life events and the brain-derived neurotrophic factor gene in bipolar disorder
    Georgina M Hosang
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    J Affect Disord 125:345-9. 2010
    ..The aim of the present study was to examine the interplay between the BDNF Val(66)Met polymorphism and stressful life events (SLEs) in bipolar disorder...
  15. ncbi request reprint Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: a genome-wide association and polygenic scoring study
    Niamh Mullins
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 165:428-37. 2014
    ..Polygenic score analysis suggests pleiotropy between psychiatric disorders and suicidal ideation whereas the tendency to act on such thoughts may have a partially independent genetic diathesis...
  16. doi request reprint Investigating the genetic variation underlying episodicity in major depressive disorder: suggestive evidence for a bipolar contribution
    Panagiotis Ferentinos
    MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, 16 De Crespigny Park, London SE5 8AF, United Kingdom Electronic address
    J Affect Disord 155:81-9. 2014
    ..We aimed to investigate the genetic underpinnings of total depressive episode count in recurrent MDD...
  17. pmc Utility of the pooling approach as applied to whole genome association scans with high-density Affymetrix microarrays
    Alexandra Schosser
    MRC SGDP Centre, Institute of Psychiatry, King s College London, London, UK
    BMC Res Notes 3:274. 2010
    ..The genotyping assay using the Affymetrix SNP 6.0 array is highly demanding on sample quality due to the small feature size, low redundancy, and lack of mismatch probes...
  18. doi request reprint Modulation of amygdala response and connectivity in depression by serotonin transporter polymorphism and diagnosis
    Sergi G Costafreda
    Department of Old Age Psychiatry, Institute of Psychiatry, King s College London, UK
    J Affect Disord 150:96-103. 2013
    ..We sought to investigate the effects of genotype as well as diagnosis in patients with depression...
  19. pmc Putative transcriptomic biomarkers in the inflammatory cytokine pathway differentiate major depressive disorder patients from control subjects and bipolar disorder patients
    Timothy R Powell
    King s College London, Institute of Psychiatry, MRC Social, Genetic and Developmental Psychiatry Centre, London, United Kingdom
    PLoS ONE 9:e91076. 2014
    ..Future research should aim to replicate findings detailed in this exploratory study in a larger medication-free sample and examine whether identified biomarkers could be used prospectively to aid clinical diagnosis...
  20. ncbi request reprint Genome-wide pharmacogenetics of antidepressant response in the GENDEP project
    Rudolf Uher
    Medical Research Council Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, SE5 8AF, London, United Kingdom
    Am J Psychiatry 167:555-64. 2010
    ..The authors performed a genome-wide association analysis of improvement of depression severity with two antidepressant drugs...
  21. ncbi request reprint Association of the dystrobrevin binding protein 1 gene (DTNBP1) in a bipolar case-control study (BACCS)
    Darya Gaysina
    MRC SGDP Centre, Institute of Psychiatry, King s College London, London, UK
    Am J Med Genet B Neuropsychiatr Genet 150:836-44. 2009
    ....