Research Topics
| Susan ChinnSummaryAffiliation: King's College London Country: UK Publications
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Publications
Reproducibility of non-specific bronchial challenge in adults: implications for design, analysis and interpretation of clinical and epidemiological studiesS Chinn
Department of Public Health Sciences, King s College London, London SE1 3QD, UK
Thorax 60:395-400. 2005..The intraclass correlation coefficient measures loss of power and degree of bias. Information is lacking on the intraclass correlation coefficient for bronchial responsiveness and factors affecting reproducibility...
Obesity and asthma: evidence for and against a causal relationSusan Chinn
Department of Public Health Sciences, King s College, London, UK
J Asthma 40:1-16. 2003....
Obesity and asthmaSusan Chinn
Division of Asthma, Allergy and Lung Biology, King s College London, UK
Paediatr Respir Rev 7:223-8. 2006..Intervention studies to prevent or reduce obesity could provide data to support or refute the association...
Optimum expression of adult lung function based on all-cause mortality: results from the Reykjavik studyS Chinn
Department of Public Health Sciences, King s College London, 42 Weston Street, London SE1 3QD, UK
Respir Med 101:601-9. 2007..Replication of these analyses in other cohort studies would inform the choice between FEV(1)/height(2) and FEV(1)/height(3)...
Incidence of asthma and net change in symptoms in relation to changes in obesityS Chinn
Respiratory Epidemiology and Public Health Group, Imperial College London, London, UK
Eur Respir J 28:763-71. 2006..These findings may help to explain the reports of a stronger association between asthma and obesity in females than in males...
Definitions of childhood obesity: current practiceS Chinn
Department of Public Health Sciences, King s College London, London, UK
Eur J Clin Nutr 60:1189-94. 2006..To review current practice in the definition of childhood obesity based on body mass index (BMI), in order to understand why the recommendations of the International Task Force on Obesity (IOTF) have not been fully adopted...
An increase in bronchial responsiveness is associated with continuing or restarting smokingSusan Chinn
Department of Public Health Sciences, King s College London, London, UK
Am J Respir Crit Care Med 172:956-61. 2005..Bronchial responsiveness (BHR) has been found to be associated with smoking, atopy, and lower lung function in cross-sectional studies, but there is little information on determinants of change in adults...
Sources of variation in forced expiratory volume in one second and forced vital capacityS Chinn
Department of Public Health Sciences, King s College London, 5th Floor Capital House, 42 Weston Street, London SE1 3QD, UK, and Department of Thoracic Medicine, Haukeland Hospital, Bergen, Norway
Eur Respir J 27:767-73. 2006..Neither national reference curves nor those based on the same ethnic group can be guaranteed to give accurate norms of lung health...
Increase in diagnosed asthma but not in symptoms in the European Community Respiratory Health SurveyS Chinn
Department of Public Health Sciences, King s College London, London SE1 3QD, UK
Thorax 59:646-51. 2004..To determine the change in the prevalence of asthma with age in young adults we analysed longitudinal data from the European Community Respiratory Health Survey...
Smoking cessation, lung function, and weight gain: a follow-up studySusan Chinn
Department of Public Health Sciences, King s College London, 5th Floor Capital House, 42 Weston Street, London SE1 3QD, UK
Lancet 365:1629-35; discussion 1600-1. 2005..We estimated the net benefit of smoking cessation, and the independent effects of smoking and weight change on change in ventilatory lung function in the international European Community Respiratory Health Survey...
Relation of bronchial responsiveness to body mass index in the ECRHS. European Community Respiratory Health SurveyS Chinn
Department of Public Health Sciences, King s College, London SE1 3QD, UK
Thorax 57:1028-33. 2002..The relation of BHR to BMI was therefore investigated in a large multicentre study...
A simple method for converting an odds ratio to effect size for use in meta-analysisS Chinn
Department of Public Health Sciences, King s College, London, 5th Floor, Capital House, 42 Weston Street, London SE1 3QD, UK
Stat Med 19:3127-31. 2000..If researchers routinely report residual standard deviation, any subsequent review can combine both odds ratios and effect sizes in a single meta-analysis when this is justified...
International definitions of overweight and obesity for children: a lasting solution?S Chinn
Department of Public Health Sciences, King s College London, 5th Floor Capital House, 42 Weston Street, London SE1 3QD, UK
Ann Hum Biol 29:306-13. 2002..For use in the UK it is unclear whether these present an advantage over equivalent definitions based on UK data...
Comparing and combining studies of bronchial responsivenessSusan Chinn
Department of Public Health Sciences, King s College, Capital House, 42 Weston Street, London SE1 3QD, UK
Thorax 57:393-5. 2002..There is no standardised protocol for the measurement of bronchial responsiveness. Results from different studies are difficult to compare and combine...
Can the increase in body mass index explain the rising trend in asthma in children?S Chinn
Department of Public Health Sciences, King s College London, London SE1 3QD, UK
Thorax 56:845-50. 2001..Trends in both in British children participating in the National Study of Health and Growth were marked from 1982 to 1994...
Prevalence and trends in overweight and obesity in three cross sectional studies of British Children, 1974-94S Chinn
Department of Public Health Sciences, King s College London, London SE1 3QD, UK
BMJ 322:24-6. 2001..To report trends in overweight and obesity, defined by new internationally agreed cut-off points, in children in the United Kingdom...
Bronchial responsiveness in atopic adults increases with exposure to cat allergenSusan Chinn
Respiratory Epidemiology and Public Health Group, National Heart and Lung Institute, Imperial College London, London, United Kingdom
Am J Respir Crit Care Med 176:20-6. 2007..The association of asthma with sensitization and allergen exposure is known to be complex. There have been few studies of bronchial responsiveness in relation to both risk factors in adults...
Cat and dust mite allergen levels, specific IgG and IgG4, and respiratory symptoms in adultsDeborah Jarvis
Respiratory Epidemiology and Public Health Group, National Heart and Lung Institute, London, UK
J Allergy Clin Immunol 119:697-704. 2007..Exposure to allergen may induce a modified T(H)2 response characterized by high IgG(4) levels, absence of IgE sensitization, and a decreased risk of allergic respiratory symptoms...
The relation of adult bronchial responsiveness to serious childhood respiratory illness in the ECRHSSusan Chinn
Department Public Health Sciences, King s College London, 5th Floor Capital House, 42 Weston Street, London SE1 3QD, UK
Respir Med 101:983-8. 2007..Respiratory symptoms in adulthood have been found to be associated with childhood respiratory infection, but few studies have analyzed adult bronchial responsiveness (BHR) with adequate adjustment for known risk factors...
Change in prevalence of IgE sensitization and mean total IgE with age and cohortDeborah Jarvis
Department of Public Health Sciences, King s College London, UK
J Allergy Clin Immunol 116:675-82. 2005..This could reflect either a decrease in sensitization with aging or a higher prevalence of sensitization in more recent birth cohorts...
Variation in physical fitness between ethnic groups in nine year oldsH Bettiol
Department of Public Health Medicine, United Medical and Dental School of Guy s Hospital, London, UK
Int J Epidemiol 28:281-6. 1999..In this study we assess the associations of social factors, ethnicity, parental health related factors, child's anthropometry, blood pressure and cholesterol measurements with cardio-respiratory fitness...
Patterns of intra-cluster correlation from primary care research to inform study design and analysisGeoffrey Adams
Department of Public Health Sciences, King's College London, Capital House, 42 Weston Street, London SE1 3QD, UK
J Clin Epidemiol 57:785-94. 2004..Studies should be designed with reference to the overall distribution of ICCs and with attention to features that increase efficiency...
Overweight and obesity trends from 1974 to 2003 in English children: what is the role of socioeconomic factors?E Stamatakis
University College London, London, UK
Arch Dis Child 90:999-1004. 2005..To examine the childhood overweight and obesity prevalence trends between 1974 and 2003 and to assess whether these trends relate to parental social class and household income...
Relationship between oxidative stress-related biomarkers and antioxidant status with asthma and atopy in young adults: a population-based studyV Garcia-Larsen
Respiratory Epidemiology and Public Health Group, National Heart and Lung Institute, Imperial College London, Manresa Road, London, U K
Clin Exp Allergy 39:379-86. 2009..This study assessed the relation between markers of oxidative stress and antioxidant status and lung function, symptoms of asthma, atopy and bronchial hyperresponsiveness (BHR) in young adults...
Atopy, wheeze and bronchial responsiveness in young Chilean adults. Do dietary antioxidants matter?V Garcia-Larsen
Division of Asthma, Allery and Lung Biology, Weston Education Centre, King s College London, London, UK
Allergy 62:714-5. 2007
Indoor nitrous acid and respiratory symptoms and lung function in adultsD L Jarvis
Division of Population Sciences and Health Care Research, King s College, 42 Weston Street, London SE1 3QD, UK
Thorax 60:474-9. 2005..These inconsistencies may be due to failure to account for the health effects of nitrous acid (HONO) which is generated directly from gas combustion and indirectly from NO2...
Social inequalities and children's height in Trinidad and TobagoR J Rona
Department of Public Health Sciences, King s College London, London, UK
Eur J Clin Nutr 57:143-50. 2003..The aim of the study was to report the association of socio-economic factors with child's height...
Intraclass correlation coefficient and outcome prevalence are associated in clustered binary dataM C Gulliford
Department of Public Health Sciences, King s College London, Capital House, 42 Weston St, London SE1 3QD, UK
J Clin Epidemiol 58:246-51. 2005..To describe the association between values for a proportion and the intraclass correlation coefficient (ICC)...
Overweight, obesity and skinfold thicknesses of children of African or Indian descent in Trinidad and TobagoM C Gulliford
Department of Public Health Sciences, King s College London, Capital House, 42 Weston St, London SE1 3QD, UK
Int J Epidemiol 30:989-98. 2001..To evaluate distribution of body mass index (BMI) and subcutaneous fat in children of African or Indian subcontinent descent living in Trinidad and Tobago...
Association of body mass index with respiratory symptoms and atopy: results from the European Community Respiratory Health SurveyD Jarvis
Department of Public Health Sciences, London, UK
Clin Exp Allergy 32:831-7. 2002..There are several reports showing that obese adults report more respiratory symptoms suggestive of asthma than those who are not obese...
Free school meals and children's social and nutritional status in Trinidad and TobagoM C Gulliford
Department of Public Health Sciences, King s College London, Capital House, 42 Weston Street, UK
Public Health Nutr 5:625-30. 2002..To evaluate the provision of free school meals in Trinidad and Tobago in relation to children's social and nutritional status...
Association between obesity and asthma in 4-11 year old children in the UKJ I Figueroa-Muñoz
Department of Public Health Sciences, King s College, 5th Floor, Capital House, 42 Weston Street, London SE1 3QD, UK
Thorax 56:133-7. 2001..We investigated, in a large sample of English and Scottish primary school children, whether there is a consistent association between fatness and asthma symptoms in Britain...
Parental smoking in childhood and adult obstructive lung disease: results from the European Community Respiratory Health SurveyC Svanes
Department of Thoracic Medicine, Haukeland University Hospital, Bergen, Norway
Thorax 59:295-302. 2004..Early exposure to parental smoking appears to influence the development of the airways and predispose to respiratory symptoms. A study was undertaken to determine whether the consequences of parental smoking could be traced in adulthood...
Effect of the choice of food composition table on nutrient estimates: a comparison between the British and American (Chilean) tablesV Garcia
Department of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile
Public Health Nutr 7:577-83. 2004..To determine the level of agreement between the American (Chilean) and British food composition tables in estimating intakes of macronutrients and antioxidants...
Pet-keeping in childhood and adult asthma and hay fever: European community respiratory health surveyCecilie Svanes
Section of Respiratory Medicine, Institute of Medicine, University of Bergen and Department of Medicine, Haraldsplass Hospital, Bergen, Norway
J Allergy Clin Immunol 112:289-300. 2003..Dogs owned in childhood seemed to protect against adult allergic disease but promote nonallergic asthma...
Geographical variation in the prevalence of positive skin tests to environmental aeroallergens in the European Community Respiratory Health Survey IP J Bousquet
Imperial College, London, UK
Allergy 62:301-9. 2007..Using the European Community Health Respiratory Survey I data, the geographical variation of sensitization to environmental allergen as measured by skin tests was established...
Changes in active and passive smoking in the European Community Respiratory Health SurveyC Janson
Dept of Medical Sciences, Respiratory Medicine and Allergology, Akademiska sjukhuset, SE 751 85 University of Uppsala, Sweden, and Department of Thoracic Medicine, Haukeland Hospital, Bergen, Norway
Eur Respir J 27:517-24. 2006..Exposure to other peoples smoking decreased quitting rates and increased the risk of starting to smoke...
The association of hepatitis A and Helicobacter pylori with sensitization to common allergens, asthma and hay fever in a population of young British adultsD Jarvis
Department of Public Health Sciences, Kings College London (Guys' Campus, London, UK
Allergy 59:1063-7. 2004..pylori was associated with lower levels of IgE sensitization, asthma or hay fever except for an isolated finding of a negative association of H. pylori infection with sensitization to grass...
Commentary: the relation of growth to socioeconomic deprivationSusan Chinn
Department of Public Health Sciences, King's College London, 5th Floor Capital House, 42 Weston Street, London SE1 3QD, UK
Int J Epidemiol 33:152-3. 2004
Non-parametric bootstrap confidence intervals for the intraclass correlation coefficientObioha C Ukoumunne
Department of Public Health Sciences, King s College London, 5th Floor, Capital House, 42 Weston Street, London SE1 3QD, UK
Stat Med 22:3805-21. 2003..Application of the bootstrap-t method to the variance stabilizing transformation of rho improved upon the performance of the standard bootstrap methods, providing close to nominal coverage...
Critical illness in systemic lupus erythematosus and the antiphospholipid syndromeF M K Williams
Department of Intensive Care, Guy's and St Thomas' Hospital Trust, St Thomas' Hospital, London, UK
Ann Rheum Dis 61:414-21. 2002..Before adjustment for these factors, only renal disease had an adverse effect on outcome but after adjustment, infection and APS reduced survival...
Obesity and asthma in childrenSusan Chinn
Am J Respir Crit Care Med 170:95; author reply 95-6. 2004
Geographic variations in the effect of atopy on asthma in the European Community Respiratory Health StudyJordi Sunyer
Environmental Respiratory Research Unit, Institut Municipal d Investigacio Medica IMIM, c Doctor Aiguader 80, 08003 Barcelona, Spain
J Allergy Clin Immunol 114:1033-9. 2004..Atopy has long been related to asthma. The prevalences of both atopy and asthma have shown substantial variation...
Physical activity and bronchial hyperresponsiveness: European Community Respiratory Health Survey IIRafea Shaaban
INSERM U700, Epidémiologie des Maladies Respiratoires, Faculte Xavier Bichat, BP 416, 16 rue Henri Huchard, 75018 Paris, France
Thorax 62:403-10. 2007..The relationship between physical activity and BHR in men and women aged 28.0-56.5 years randomly selected from 24 centres in 11 countries participating in the European Community Respiratory Health Survey II was investigated...
Nondifferential disease misclassification may bias incidence risk ratios away from the nullJuha Pekkanen
Unit of Environmental Epidemiology, National Public Health Institute, P O Box 95, 70701 Kuopio, Finland
J Clin Epidemiol 59:281-9. 2006..Although the effect of disease misclassification on estimated incidence risk ratios has otherwise been extensively explored, the effect of disease misclassification at baseline has not previously been analyzed...
Distribution and determinants of house dust mite allergens in Europe: the European Community Respiratory Health Survey IIJan Paul Zock
Center for Research in Environmental Epidemiology, Municipal Institute of Medical Research, Barcelona, Spain
J Allergy Clin Immunol 118:682-90. 2006....
Cat allergen level: its determinants and relationship to specific IgE to cat across European centersJoachim Heinrich
GSF, National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
J Allergy Clin Immunol 118:674-81. 2006..Cat allergen level in settled house dust and its determinants in Europe are unknown...
Fetal fibronectin test predicts delivery before 30 weeks of gestation in high risk women, but increases anxietyAndrew Shennan
Maternal and Fetal Research Unit, Department of Women's Health, Guy's, King's and St Thomas' School of Medicine, King's College London, London SE1 7EH, UK
BJOG 112:293-8. 2005..CONCLUSIONS: Fetal fibronectin was most efficient as a predictor of preterm spontaneous delivery <30 weeks of gestation, but was associated with high levels of anxiety...
Incidence of chronic obstructive pulmonary disease in a cohort of young adults according to the presence of chronic cough and phlegmRoberto de Marco
Sezione di Epidemiologia and Statistica Medica, Dipartimento di Medicina e Sanita Pubblica, Universita degli Studi di Verona, c o Istituti Biologici II, Strada Le Grazie 8 37134, Verona, Italy
Am J Respir Crit Care Med 175:32-9. 2007..The few prospective studies aimed at assessing the incidence of chronic obstructive pulmonary disease (COPD) in relation to the presence of chronic cough/phlegm have produced contrasting results...
