K R Chaudhuri

Summary

Affiliation: King's College Hospital
Country: UK

Publications

  1. ncbi request reprint 'Sleep attacks' or 'unintended sleep episodes' occur with dopamine agonists: is this a class effect?
    K Ray Chaudhuri
    Guy s King s and St Thomas Medical School, King s College London, London, United Kingdom
    Drug Saf 25:473-83. 2002
  2. ncbi request reprint The basis for day and night-time control of symptoms of Parkinson's disease
    K Ray Chaudhuri
    Regional Movement Disorders Unit, King s College Hospital, London, UK
    Eur J Neurol 9:40-3. 2002
  3. pmc The Parkinson's disease sleep scale: a new instrument for assessing sleep and nocturnal disability in Parkinson's disease
    K R Chaudhuri
    Department of Neurology, King s College Hospital, London SE5, UK
    J Neurol Neurosurg Psychiatry 73:629-35. 2002
  4. ncbi request reprint Autonomic dysfunction in movement disorders
    K R Chaudhuri
    Regional Movement Disorders and Autonomic Unit, Department of Neurology, King s College Hospital, London, UK
    Curr Opin Neurol 14:505-11. 2001
  5. ncbi request reprint Achieving 24-hour control of Parkinson's disease symptoms: use of objective measures to improve nocturnal disability
    K R Chaudhuri
    Regional Movement Disorders Unit, King s College Hospital, London, UK
    Eur Neurol 46:3-10. 2001
  6. ncbi request reprint A study of excessive daytime sleepiness and its clinical significance in three groups of Parkinson's disease patients taking pramipexole, cabergoline and levodopa mono and combination therapy
    S Pal
    Regional Movement Disorders Unit, King's College Hospital, University Hospital of Lewisham and Guy's King's and St Thomas' School of Medicine, London, United Kingdom
    J Neural Transm 108:71-7. 2001
  7. doi request reprint Depression and anxiety related subtypes in Parkinson's disease
    Richard G Brown
    King s College London, Institute of Psychiatry, Department of Psychology PO77, De Crespigny Park, London SE5 8AF, UK
    J Neurol Neurosurg Psychiatry 82:803-9. 2011
  8. pmc The economic costs of progressive supranuclear palsy and multiple system atrophy in France, Germany and the United Kingdom
    Paul McCrone
    Health Service and Population Research Department, Institute of Psychiatry, King s College London, London, United Kingdom
    PLoS ONE 6:e24369. 2011
  9. ncbi request reprint Correlating rates of cerebral atrophy in Parkinson's disease with measures of cognitive decline
    M T Hu
    Robert Steiner MR Unit, Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom
    J Neural Transm 108:571-80. 2001
  10. ncbi request reprint Erythropoietin deficiency and anaemia in multiple system atrophy
    A S Winkler
    Regional Movement Disorders, and Dystonia Unit, University Department of Clinical Neurosciences, King's College Hospital, London, United Kingdom
    Mov Disord 16:233-9. 2001

Detail Information

Publications35

  1. ncbi request reprint 'Sleep attacks' or 'unintended sleep episodes' occur with dopamine agonists: is this a class effect?
    K Ray Chaudhuri
    Guy s King s and St Thomas Medical School, King s College London, London, United Kingdom
    Drug Saf 25:473-83. 2002
    ..The latter may identify sleep disorders such as secondary narcolepsy which may benefit from the use of a wakefulness promoting agent...
  2. ncbi request reprint The basis for day and night-time control of symptoms of Parkinson's disease
    K Ray Chaudhuri
    Regional Movement Disorders Unit, King s College Hospital, London, UK
    Eur J Neurol 9:40-3. 2002
    ....
  3. pmc The Parkinson's disease sleep scale: a new instrument for assessing sleep and nocturnal disability in Parkinson's disease
    K R Chaudhuri
    Department of Neurology, King s College Hospital, London SE5, UK
    J Neurol Neurosurg Psychiatry 73:629-35. 2002
    ..No formal instruments are available for quantifying sleep problems in Parkinson's disease...
  4. ncbi request reprint Autonomic dysfunction in movement disorders
    K R Chaudhuri
    Regional Movement Disorders and Autonomic Unit, Department of Neurology, King s College Hospital, London, UK
    Curr Opin Neurol 14:505-11. 2001
    ..These studies have helped progress in various diagnostic and management parameters in relation to autonomic dysfunction and movement disorders...
  5. ncbi request reprint Achieving 24-hour control of Parkinson's disease symptoms: use of objective measures to improve nocturnal disability
    K R Chaudhuri
    Regional Movement Disorders Unit, King s College Hospital, London, UK
    Eur Neurol 46:3-10. 2001
    ..In this paper, we discuss the development of this scale, its clinical use and how the scale could be used to devise targeted treatment strategies for nocturnal problems in PD...
  6. ncbi request reprint A study of excessive daytime sleepiness and its clinical significance in three groups of Parkinson's disease patients taking pramipexole, cabergoline and levodopa mono and combination therapy
    S Pal
    Regional Movement Disorders Unit, King's College Hospital, University Hospital of Lewisham and Guy's King's and St Thomas' School of Medicine, London, United Kingdom
    J Neural Transm 108:71-7. 2001
    ..b) Increasing age, advanced disease, and higher treatment dose appear important predictors for EDS. c) Driving regulations should be reviewed accordingly...
  7. doi request reprint Depression and anxiety related subtypes in Parkinson's disease
    Richard G Brown
    King s College London, Institute of Psychiatry, Department of Psychology PO77, De Crespigny Park, London SE5 8AF, UK
    J Neurol Neurosurg Psychiatry 82:803-9. 2011
    ..There is growing evidence for heterogeneity in PD in the motor and cognitive domains, with implications for pathophysiology and outcome. Similar heterogeneity may exist in the domain of depression and anxiety...
  8. pmc The economic costs of progressive supranuclear palsy and multiple system atrophy in France, Germany and the United Kingdom
    Paul McCrone
    Health Service and Population Research Department, Institute of Psychiatry, King s College London, London, United Kingdom
    PLoS ONE 6:e24369. 2011
    ..Formal and unpaid costs were significantly higher the more severe the illness, as indicated by the Parkinson's Plus Symptom scale. There was a significant inverse relationship between service and unpaid care costs...
  9. ncbi request reprint Correlating rates of cerebral atrophy in Parkinson's disease with measures of cognitive decline
    M T Hu
    Robert Steiner MR Unit, Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom
    J Neural Transm 108:571-80. 2001
    ....
  10. ncbi request reprint Erythropoietin deficiency and anaemia in multiple system atrophy
    A S Winkler
    Regional Movement Disorders, and Dystonia Unit, University Department of Clinical Neurosciences, King's College Hospital, London, United Kingdom
    Mov Disord 16:233-9. 2001
    ..Serum EPO levels in PD patients were within normal range. A subset of MSA patients has anaemia and postural hypotension, which may be associated with EPO deficiency. This may have therapeutic implications...
  11. doi request reprint Long-term clinical and positron emission tomography outcome of fetal striatal transplantation in Huntington's disease
    I Reuter
    Academic Department of Neuroscience, Kings College Hospital, London, UK
    J Neurol Neurosurg Psychiatry 79:948-51. 2008
    ..The other patient did not improve clinically or radiologically. Our results indicate that striatal transplantation in HD may be beneficial but further studies are needed to confirm this...
  12. ncbi request reprint Measuring brain stem and cerebellar damage in parkinsonian syndromes using diffusion tensor MRI
    C R V Blain
    King s College London, Institute of Psychiatry, MRC Centre for Neurodegeneration, Department of Clinical Neuroscience, London, UK
    Neurology 67:2199-205. 2006
    ....
  13. ncbi request reprint No association between Parkinson's disease and low-activity alleles of catechol O-methyltransferase
    F Hoda
    Section of Molecular Genetics, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, United Kingdom
    Biochem Biophys Res Commun 228:780-4. 1996
    ..However it remains possible that allelic variation in COMT influences severity, type of pathology or treatment response to levodopa or COMT inhibitors...
  14. pmc A multicentre longitudinal observational study of changes in self reported health status in people with Parkinson's disease left untreated at diagnosis
    D Grosset
    Institute of Neurological Sciences, Glasgow, UK
    J Neurol Neurosurg Psychiatry 78:465-9. 2007
    ..Some favour treatment at diagnosis while others opt for a "wait and watch" policy. The effect of the latter policy on the self reported health status of people with PD is unknown...
  15. ncbi request reprint Use of the dopamine agonist cabergoline in the treatment of movement disorders
    Aimee Di Marco
    Movement Disorders Unit, Mapother House, King s College Hospital, Denmark Hill, London, UK
    Expert Opin Pharmacother 3:1481-7. 2002
    ..Audits of the clinical efficacy of cabergoline indicate that it is well-tolerated and has an acceptable side effect profile...
  16. ncbi request reprint The range and nature of sleep dysfunction in untreated Parkinson's disease (PD). A comparative controlled clinical study using the Parkinson's disease sleep scale and selective polysomnography
    V Dhawan
    Regional Movement Disorders Unit, King s College Hospital, UK
    J Neurol Sci 248:158-62. 2006
    ..Furthermore, polysomnography in "sleepy" PD patients may help diagnose unrecognised conditions such as periodic limb movement of sleep (PLMS), obstructive sleep apnoea (OSA) and REM Sleep Behaviour Disorder...
  17. ncbi request reprint The non-motor symptom complex of Parkinson's disease: a comprehensive assessment is essential
    K Ray Chaudhuri
    Neurology, Kings College Hospital, Ruskin Wing, Denmark Hill, London SE5 9RS, United Kindgom
    Curr Neurol Neurosci Rep 5:275-83. 2005
    ..Recently, an international, multidisciplinary PD-NMS group has developed an integrated questionnaire and scale to assess NMS of PD in a comprehensive manner. This will help improve care and treatment of PD in the future...
  18. ncbi request reprint Transdermal rotigotine: a new non-ergot dopamine agonist for the treatment of Parkinson's disease
    Y Naidu
    University Hospital Lewisham, National Parkinson Foundation Centre of Excellence and Regional Movement Disorders Unit, UK
    Expert Opin Drug Deliv 4:111-8. 2007
    ..Clinical trials demonstrate the efficacy of rotigotine in early and advanced Parkinson's disease, with important implications for treatment of non-motor symptoms of Parkinson's disease...
  19. ncbi request reprint Prevalence of nonmotor symptoms in Parkinson's disease in an international setting; study using nonmotor symptoms questionnaire in 545 patients
    Pablo Martinez-Martin
    Unit of Neuroepidemiology, National Center for Epidemiology, Carlos III Institute of Health, Madrid, Spain
    Mov Disord 22:1623-9. 2007
    ....
  20. ncbi request reprint Clinical significance of RLS
    Wayne A Hening
    UMDNJ RW Johnson Medical School, New Brunswick, New Jersey, USA
    Mov Disord 22:S395-400. 2007
    ..In dialysis patients, RLS has been found to be a risk factor for mortality. Therefore, those with RLS who have clinically significant symptoms suffer increased morbidity and are at risk for impaired long-term medical outcomes...
  21. ncbi request reprint Serum prolactin levels in Parkinson's disease and multiple system atrophy
    Andrea Sylvia Winkler
    Consultant Neurologist, King s College Hospital, Mapother House, Denmark Hill, London SE5 9RS, UK ray chaudhuri kingshc nhs
    Clin Auton Res 12:393-8. 2002
    ..Baseline PRL levels might differentiate between early MSA and IPD, being higher in MSA. However, orthostatic stress using HUT appears unable to differentiate between MSA and IPD...
  22. doi request reprint Efficacy of rotigotine for treatment of moderate-to-severe restless legs syndrome: a randomised, double-blind, placebo-controlled trial
    Claudia Trenkwalder
    Paracelsus Elena Hospital, Kassel, Germany
    Lancet Neurol 7:595-604. 2008
    ..Continuous administration of a dopamine agonist could be used to treat patients with restless legs syndrome. Our aim was to investigate the efficacy of transdermal rotigotine in the treatment of idiopathic restless legs syndrome...
  23. doi request reprint Health-related quality of life in Asian and other ethnic groups with Parkinson's disease
    K Ray Chaudhuri
    Eur J Neurol 15:642. 2008
  24. doi request reprint Quantitation of non-motor symptoms in Parkinson's disease
    K Ray Chaudhuri
    National Parkinson Foundation Centre of Excellence, King s College Hospital, University Hospital Lewisham, Kings College and Institute of Psychiatry, London, UK
    Eur J Neurol 15:2-7. 2008
    ....
  25. ncbi request reprint The frequency and significance of 'striatal toe' in parkinsonism
    Andrea Sylvia Winkler
    Regional Movement Disorders and Autonomic Unit, King s College Hospital and Guy s, King s and St Thomas Medical School, London, UK
    Parkinsonism Relat Disord 9:97-101. 2002
    ..The possible relevance of these findings is discussed...
  26. ncbi request reprint Nocturnal symptom complex in PD and its management
    K Ray Chaudhuri
    Regional Movement Disorders Unit, King s College Hospital, University Hospital Lewisham, Guy s, King s and St Thomas School of Biomedical Medicine, King s College, London, United Kingdom
    Neurology 61:S17-23. 2003
  27. ncbi request reprint Dopamine agonist switching in Parkinson's disease
    David Stewart
    Victoria Infirmary, Glasgow G42 9TY
    Hosp Med 65:215-9. 2004
    ..This article explores reasons for making such a switch, and provides practical guidance on performing it...
  28. ncbi request reprint Parkinson's Disease Sleep Scale: validation study of a Spanish version
    Pablo Martinez-Martin
    Neuroepidemiology Unit, National Centre for Epidemiology, Carlos III Institute of Public Health, and the Spanish Network HOHSR, Madrid, Spain
    Mov Disord 19:1226-32. 2004
    ..The assessment of PD sleep disorders with the PDSS met some basic standards required for health status measures...
  29. ncbi request reprint Clinical assessment of nocturnal disability in Parkinson's disease: the Parkinson's Disease Sleep Scale
    K Ray Chaudhuri
    Regional Movement Disorders Unit, King s College Hospital, University Hospital Lewisham, Guy s, King s and St Thomas School of Biomedical Medicine, King s College, London, United Kingdom
    Neurology 63:S17-20. 2004
  30. ncbi request reprint Restless legs syndrome
    K Ray Chaudhuri
    N Engl J Med 349:815. 2003
  31. pmc Long duration asymmetrical postural tremor is likely to predict development of Parkinson's disease and not essential tremor: clinical follow up study of 13 cases
    K Ray Chaudhuri
    Department of Neurology, King s College Hospital, Denmark Hill, London, SE5 9RS, UK
    J Neurol Neurosurg Psychiatry 76:115-7. 2005
    ..Patients presenting with asymmetrical postural tremor with or without mild rest tremor may be diagnosed as having essential tremor (ET), although there is considerable diagnostic uncertainty as to the long term outcome of these patients...
  32. ncbi request reprint Retrospective evaluation of cardio-pulmonary fibrotic side effects in symptomatic patients from a group of 234 Parkinson's disease patients treated with cabergoline
    V Dhawan
    Department of Neurology, University Hospital Lewisham, London, United Kingdom
    J Neural Transm 112:661-8. 2005
    ..Cabergoline a widely used, well-tolerated EDA which has also been recently implicated in relation to fibrotic side effects although the evidence base for this is not sound...
  33. ncbi request reprint Non-motor symptoms of Parkinson's disease: diagnosis and management
    K Ray Chaudhuri
    Movement Disorders Unit, Kings College Hospital, Guy s King s and St Thomas School of Medicine, London, UK
    Lancet Neurol 5:235-45. 2006
    ..Inevitably, the development of treatments that can slow or prevent the progression of Parkinson's disease and its multicentric neurodegeneration provides the best hope of curing non-motor symptoms...
  34. ncbi request reprint Sleep-related problems of Parkinson's disease
    V Dhawan
    Movement Disorders Unit, Kings College Hospital, University Hospital Lewisham, Guy s King s and St Thomas School of Medicine, London, UK
    Age Ageing 35:220-8. 2006
    ..To define the epidemiology, characteristics and aetiology of nocturnal symptoms and sleep disorders in patients with Parkinson's disease (PD) and evaluate the available methods for their diagnosis and management...
  35. ncbi request reprint Valvular heart disease and fibrotic reactions may be related to ergot dopamine agonists, but non-ergot agonists may also not be spared
    K Ray Chaudhuri
    Mov Disord 19:1522-3. 2004