Research Topics
| M R BroomeSummaryAffiliation: King's College London Country: UK Publications
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Detail Information
Publications
What causes the onset of psychosis?Matthew R Broome
Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
Schizophr Res 79:23-34. 2005..Thus, a plausible model of the onset of psychosis needs to draw not only on neuroscience, but also on the insights of social psychiatry and cognitive psychology...
Delusion formation and reasoning biases in those at clinical high risk for psychosisM R Broome
Section of Neuroimaging, Division of Psychological Medicine, Institute of Psychiatry, London, UK
Br J Psychiatry Suppl 51:s38-42. 2007..Cognitive models propose that faulty appraisal of anomalous experiences is critical in developing psychosis, particularly delusions. A data gathering bias may be fundamental to abnormal appraisal...
Altered brain function directly related to structural abnormalities in people at ultra high risk of psychosis: longitudinal VBM-fMRI studyP Fusar-Poli
Department of Psychosis Studies, King s College London, King s Health Partners, Institute of Psychiatry, UK
J Psychiatr Res 45:190-8. 2011..However, the longitudinal course of these abnormalities, and how they relate to subsequent clinical and functional outcome is relatively unclear...
Spatial working memory in individuals at high risk for psychosis: longitudinal fMRI studyP Fusar-Poli
Institute of Psychiatry, King s Health Partners, King s College London, UK
Schizophr Res 123:45-52. 2010..The longitudinal dynamic course of the neurofunctional abnormalities underlying liability to psychosis and their relation to clinical outcomes is unknown...
Neural correlates of visuospatial working memory in the 'at-risk mental state'M R Broome
Psychosis Clinical Academic Group, Institute of Psychiatry, King s College London, UK
Psychol Med 40:1987-99. 2010..We used functional magnetic resonance imaging (fMRI) to examine the neural substrate of SWM in the ARMS and in patients who had just developed schizophrenia...
Delusional ideation, manic symptomatology and working memory in a cohort at clinical high-risk for psychosis: a longitudinal studyM R Broome
Department of Psychosis Studies, Institute of Psychiatry, King s College London, London, UK
Eur Psychiatry 27:258-63. 2012....
Differential activation of temporal cortex during sentence completion in schizophrenic patients with and without formal thought disorderT T Kircher
Department of Psychological Medicine, Institute of Psychiatry and GKT SchooI of Medicine, De Crespigny Park, London SE5 8AF, UK
Schizophr Res 50:27-40. 2001....
Economic impact of early intervention in people at high risk of psychosisL R Valmaggia
OASIS and Department of Psychological Medicine, Institute of Psychiatry, King s College London, UK
Psychol Med 39:1617-26. 2009..We assessed the cost-effectiveness of Outreach and Support in South London (OASIS), a service for people with an at-risk mental state (ARMS) for psychosis...
Insight in individuals with an At Risk Mental StateJulia M Lappin
King s College London Institute of Psychiatry, PO63, Division of Psychological Medicine, London SE5 8AF, UK
Schizophr Res 90:238-44. 2007..We compared the level and quality of insight in the ARMS and in first episode psychosis...
Misattribution of external speech in patients with hallucinations and delusionsPaul P Allen
Section of Neuroimaging, Division of Psychological Medicine, Institute of Psychiatry, P O BOX 67, Denmark Hill, London SE5 8AF, UK
Schizophr Res 69:277-87. 2004..We examined whether patients with hallucinations and delusions would demonstrate an externalising bias on a task that did not involve cognitive self-monitoring...
Superior temporal lobe dysfunction and frontotemporal dysconnectivity in subjects at risk of psychosis and in first-episode psychosisNicolas A Crossley
Section of Neuroimaging, Division of Psychological Medicine, Institute of Psychiatry, King s College London, London, United Kingdom
Hum Brain Mapp 30:4129-37. 2009..However, the stage of the disorder at which these functional alterations occur is unclear. We addressed this issue by using functional MRI (fMRI) to study subjects in the prodromal and first episode phases of schizophrenia...
Faulty suppression of irrelevant material in patients with thought disorder linked to attenuated frontotemporal activationS M Arcuri
Department of Psychosis Studies, Institute of Psychiatry, King s College London, London, UK
Schizophr Res Treatment 2012:176290. 2012..This network is implicated in the inhibition of automatically primed stimuli and impairment of its function interferes with language processing and contributes to the production of incoherent speech...
Neural correlates of executive function and working memory in the 'at-risk mental state'Matthew R Broome
Division of Psychological Medicine, Institute of Psychiatry, King s College London, UK
Br J Psychiatry 194:25-33. 2009..People with prodromal symptoms have a very high risk of developing psychosis...
Effects of acute antipsychotic treatment on brain activation in first episode psychosis: an fMRI studyP Fusar-Poli
Division of Psychological Medicine Institute of Psychiatry, King s College London, De Crespigny Park, SE58AF, London, UK
Eur Neuropsychopharmacol 17:492-500. 2007..These effects need to be considered when interpreting group differences in activation between medicated patients and controls...
Neural correlates of movement generation in the 'at-risk mental state'Matthew R Broome
Section of Neuroimaging, Division of Psychological Medicine, Institute of Psychiatry, King s College London, London, UK
Acta Psychiatr Scand 122:295-301. 2010..We examined the neurocognitive basis of this vulnerability by using functional MRI to study subjects with an at-risk mental state (ARMS) while they performed a random movement generation task...
Conceptual issues in psychiatric neuroimagingPaolo Fusar-Poli
PO 67, Section of Neuroimaging, Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London, UK
Curr Opin Psychiatry 19:608-12. 2006....
Outreach and support in south London (OASIS): implementation of a clinical service for prodromal psychosis and the at risk mental stateMatthew R Broome
OASIS, PO 67, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
Eur Psychiatry 20:372-8. 2005..CONCLUSION: It is feasible to provide a clinical service for people with prodromal symptoms in a deprived inner city area with a large ethnic minority population...
Regionally localized thinning of the cerebral cortex in schizophreniaGina R Kuperberg
Department of Psychiatry, Massachusetts General Hospital and Athinoula A Martinos Center for Biomedical Imaging, Charlestown, 02129, USA
Arch Gen Psychiatry 60:878-88. 2003....
