Sagnik Bhattacharyya

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint A family genetic study of clinical subtypes of obsessive-compulsive disorder
    Sagnik Bhattacharyya
    Institute of Psychiatry, London, UK
    Psychiatr Genet 15:175-80. 2005
  2. ncbi request reprint Imaging the neural effects of cannabinoids: current status and future opportunities for psychopharmacology
    S Bhattacharyya
    Section of Neuroimaging, Box PO67, Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, King s College London, De Crespigny Park, London, UK
    Curr Pharm Des 15:2603-14. 2009
  3. pmc Opposite effects of delta-9-tetrahydrocannabinol and cannabidiol on human brain function and psychopathology
    Sagnik Bhattacharyya
    Section of Neuroimaging, Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, King s College London, London, UK
    Neuropsychopharmacology 35:764-74. 2010
  4. ncbi request reprint Depressive and anxiety disorder comorbidity in obsessive compulsive disorder
    Sagnik Bhattacharyya
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India
    Psychopathology 38:315-9. 2005
  5. ncbi request reprint Glutamatergic dysfunction--newer targets for anti-obsessional drugs
    Sagnik Bhattacharyya
    Section of Neuroimaging, Box 67, Division of Psychological Medicine, Institute of Psychiatry, King s College London, SE5 8AF, UK
    Recent Pat CNS Drug Discov 2:47-55. 2007
  6. doi request reprint Anti-brain autoantibodies and altered excitatory neurotransmitters in obsessive-compulsive disorder
    Sagnik Bhattacharyya
    Division of Psychological Medicie and Psychiatry, Section of Neuroimaging, Institute of Psychiatry, King s College London, London, UK
    Neuropsychopharmacology 34:2489-96. 2009
  7. doi request reprint Modulation of mediotemporal and ventrostriatal function in humans by Delta9-tetrahydrocannabinol: a neural basis for the effects of Cannabis sativa on learning and psychosis
    Sagnik Bhattacharyya
    Section of Neuroimaging, Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, King s College London, Box P067, De Crespigny Park, London SE5 8AF, England
    Arch Gen Psychiatry 66:442-51. 2009
  8. doi request reprint Modulation of effective connectivity during emotional processing by Delta 9-tetrahydrocannabinol and cannabidiol
    Paolo Fusar-Poli
    Neuroimaging Section, Division of Psychological Medicine, Institute of Psychiatry, King s College London, UK
    Int J Neuropsychopharmacol 13:421-32. 2010
  9. doi request reprint Distinct effects of {delta}9-tetrahydrocannabinol and cannabidiol on neural activation during emotional processing
    Paolo Fusar-Poli
    Neuroimaging Section, Division of Psychological Medicine, PO67, Institute of Psychiatry, London SE58AF, England
    Arch Gen Psychiatry 66:95-105. 2009
  10. doi request reprint Induction of psychosis by Δ9-tetrahydrocannabinol reflects modulation of prefrontal and striatal function during attentional salience processing
    Sagnik Bhattacharyya
    Department of Psychosis Studies, Institute of Psychiatry, King s College London, De Crespigny Park, London, England
    Arch Gen Psychiatry 69:27-36. 2012

Detail Information

Publications23

  1. ncbi request reprint A family genetic study of clinical subtypes of obsessive-compulsive disorder
    Sagnik Bhattacharyya
    Institute of Psychiatry, London, UK
    Psychiatr Genet 15:175-80. 2005
    ..The current study was conducted to determine familiality of checker and washer subtypes of obsessive-compulsive disorder compared with normal controls...
  2. ncbi request reprint Imaging the neural effects of cannabinoids: current status and future opportunities for psychopharmacology
    S Bhattacharyya
    Section of Neuroimaging, Box PO67, Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, King s College London, De Crespigny Park, London, UK
    Curr Pharm Des 15:2603-14. 2009
    ..Further, we also discuss how combining neuroimaging and pharmacological challenge with cannabinoids may open up newer avenues for target identification and validation in psychopharmacology...
  3. pmc Opposite effects of delta-9-tetrahydrocannabinol and cannabidiol on human brain function and psychopathology
    Sagnik Bhattacharyya
    Section of Neuroimaging, Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, King s College London, London, UK
    Neuropsychopharmacology 35:764-74. 2010
    ..Delta-9-THC and CBD can have opposite effects on regional brain function, which may underlie their different symptomatic and behavioral effects, and CBD's ability to block the psychotogenic effects of Delta-9-THC...
  4. ncbi request reprint Depressive and anxiety disorder comorbidity in obsessive compulsive disorder
    Sagnik Bhattacharyya
    Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India
    Psychopathology 38:315-9. 2005
    ..Although western studies have looked at this issue, there are no reports from India investigating anxiety and depressive comorbidity in adult OCD...
  5. ncbi request reprint Glutamatergic dysfunction--newer targets for anti-obsessional drugs
    Sagnik Bhattacharyya
    Section of Neuroimaging, Box 67, Division of Psychological Medicine, Institute of Psychiatry, King s College London, SE5 8AF, UK
    Recent Pat CNS Drug Discov 2:47-55. 2007
    ..In this article we focus in detail on the rationale for targeting glutamatergic agents as well as review the recent important patents for compounds that have emerged from these studies...
  6. doi request reprint Anti-brain autoantibodies and altered excitatory neurotransmitters in obsessive-compulsive disorder
    Sagnik Bhattacharyya
    Division of Psychological Medicie and Psychiatry, Section of Neuroimaging, Institute of Psychiatry, King s College London, London, UK
    Neuropsychopharmacology 34:2489-96. 2009
    ..The results of our study implicate autoimmune mechanisms in the pathogenesis of OCD and also provide preliminary evidence that autoantibodies against BG and thalamus may cause OCD by modulating excitatory neurotransmission...
  7. doi request reprint Modulation of mediotemporal and ventrostriatal function in humans by Delta9-tetrahydrocannabinol: a neural basis for the effects of Cannabis sativa on learning and psychosis
    Sagnik Bhattacharyya
    Section of Neuroimaging, Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, King s College London, Box P067, De Crespigny Park, London SE5 8AF, England
    Arch Gen Psychiatry 66:442-51. 2009
    ..Cannabis sativa use can impair verbal learning, provoke acute psychosis, and increase the risk of schizophrenia. It is unclear where C. sativa acts in the human brain to modulate verbal learning and to induce psychotic symptoms...
  8. doi request reprint Modulation of effective connectivity during emotional processing by Delta 9-tetrahydrocannabinol and cannabidiol
    Paolo Fusar-Poli
    Neuroimaging Section, Division of Psychological Medicine, Institute of Psychiatry, King s College London, UK
    Int J Neuropsychopharmacol 13:421-32. 2010
    ..This is the first study to show that the disruption of prefrontal-subocritical connectivity by CBD may represent neurophysiological correlates of its anxiolytic properties...
  9. doi request reprint Distinct effects of {delta}9-tetrahydrocannabinol and cannabidiol on neural activation during emotional processing
    Paolo Fusar-Poli
    Neuroimaging Section, Division of Psychological Medicine, PO67, Institute of Psychiatry, London SE58AF, England
    Arch Gen Psychiatry 66:95-105. 2009
    ..Cannabis use can both increase and reduce anxiety in humans. The neurophysiological substrates of these effects are unknown...
  10. doi request reprint Induction of psychosis by Δ9-tetrahydrocannabinol reflects modulation of prefrontal and striatal function during attentional salience processing
    Sagnik Bhattacharyya
    Department of Psychosis Studies, Institute of Psychiatry, King s College London, De Crespigny Park, London, England
    Arch Gen Psychiatry 69:27-36. 2012
    ..Cannabis can induce acute psychotic symptoms, and its chronic use may increase the risk of schizophrenia. We investigated whether its psychotic effects are mediated through an influence on attentional salience processing...
  11. doi request reprint Neural basis of Delta-9-tetrahydrocannabinol and cannabidiol: effects during response inhibition
    Stefan J Borgwardt
    Section of Neuroimaging, Institute of Psychiatry, King s College London, United Kingdom
    Biol Psychiatry 64:966-73. 2008
    ..This study examined the effect of Delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) on brain activation during a motor inhibition task...
  12. pmc Modulation of auditory and visual processing by delta-9-tetrahydrocannabinol and cannabidiol: an FMRI study
    Toby T Winton-Brown
    Department of Psychosis Studies, Institute of Psychiatry, King s Health Partners, London, UK
    Neuropsychopharmacology 36:1340-8. 2011
    ..Single doses of THC and CBD differently modulate brain function in areas that process auditory and visual stimuli and relate to induced psychotic symptoms...
  13. doi request reprint Altered medial temporal activation related to local glutamate levels in subjects with prodromal signs of psychosis
    Isabel Valli
    Department of Psychosis Studies, King s College London, London, United Kingdom
    Biol Psychiatry 69:97-9. 2011
    ..However, although animal models of psychosis suggest that these two abnormalities are interrelated, their relationship in humans has yet to be investigated...
  14. ncbi request reprint Neural mechanisms for the cannabinoid modulation of cognition and affect in man: a critical review of neuroimaging studies
    Sagnik Bhattacharyya
    Department of Psychosis Studies, King s College London, Institute of Psychiatry, 6th Floor, Main Building, PO Box 067, De Crespigny Park, SE5 8AF, London, UK
    Curr Pharm Des 18:5045-54. 2012
    ....
  15. doi request reprint Substance use and regional gray matter volume in individuals at high risk of psychosis
    James M Stone
    Department of Psychosis Studies, Institute of Psychiatry, King s College London, United Kingdom
    Eur Neuropsychopharmacol 22:114-22. 2012
    ..However, alcohol, tobacco and cannabis at low to moderate intake may be associated with lower gray matter in both ARMS subjects and healthy volunteers-possibly representing low-level cortical damage or change in neural plasticity...
  16. doi request reprint Presynaptic striatal dopamine dysfunction in people at ultra-high risk for psychosis: findings in a second cohort
    Alice Egerton
    Department of Psychosis Studies, Institute of Psychiatry, King s College London, London, United Kingdom
    Biol Psychiatry 74:106-12. 2013
    ..The purpose of this study was to test if this finding would be replicated in a second UHR cohort...
  17. pmc Disruption of frontal θ coherence by Δ9-tetrahydrocannabinol is associated with positive psychotic symptoms
    Paul D Morrison
    The Biomedical Research Centre, Institute of Psychiatry, King s College London, Denmark Hill, UK
    Neuropsychopharmacology 36:827-36. 2011
    ..The results reveal that the pro-psychotic effects of THC might be related to impaired network dynamics with impaired communication between the right and left frontal lobes...
  18. doi request reprint Effect of BDNF val(66)met polymorphism on declarative memory and its neural substrate: a meta-analysis
    Joseph P Kambeitz
    Department of Psychosis Studies, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    Neurosci Biobehav Rev 36:2165-77. 2012
    ..These results underscore the role of BDNF in moderating variability between individuals in human memory performance and in mediating some of the neurocognitive impairments underlying neuropsychiatric disorders...
  19. doi request reprint Glutamate dysfunction in people with prodromal symptoms of psychosis: relationship to gray matter volume
    James M Stone
    Institute of Psychiatry, King s College London, University College London, United Kingdom
    Biol Psychiatry 66:533-9. 2009
    ..Here we determine whether changes in brain glutamate are present in subjects at ultra high risk of developing psychosis and whether these changes are related to reductions in cortical gray matter volume...
  20. pmc Alterations in white matter evident before the onset of psychosis
    Francesco Carletti
    Department of Psychosis Studies, Institute of Psychiatry, King s College London, London, UK
    Schizophr Bull 38:1170-9. 2012
    ..We addressed these issues by using diffusion tensor imaging (DTI) to study subjects at ultra high risk (UHR) of psychosis before and after the onset of illness...
  21. ncbi request reprint Glutamatergic dysfunction in OCD
    Kaushik Chakrabarty
    Department of Molecular Neurobiochemistry, International Graduate School of Neuroscience, Ruhr University Bochum, Bochum, Germany
    Neuropsychopharmacology 30:1735-40. 2005
    ..Our study provides preliminary evidence implicating glutamatergic excess in the pathophysiology of OCD, which needs to be further explored by studies from other centers involving larger sample sets from different age groups...
  22. ncbi request reprint Late onset OCD
    Sagnik Bhattacharyya
    Aust N Z J Psychiatry 38:477-8. 2004
  23. ncbi request reprint Early-onset obsessive-compulsive disorder
    Sagnik Bhattacharyya
    Can J Psychiatry 48:352-3. 2003