Basson M, van Ravenswaaij Arts C. Functional Insights into Chromatin Remodelling from Studies on CHARGE Syndrome. Trends Genet. 2015;31:600-11 pubmed publisher
..The emerging picture from this work suggests that the mechanisms by which CHD7 fine-tunes gene expression are context specific, consistent with the pleiotropic nature of CHARGE syndrome. ..
Basson M, Akbulut S, Watson Johnson J, Simon R, Carroll T, Shakya R, et al. Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction. Dev Cell. 2005;8:229-39 pubmed
..These results demonstrate the importance of negative feedback regulation of RTK signaling during kidney induction and suggest that failures in feedback control may underlie some human congenital kidney malformations. ..