E J Lamb

Summary

Affiliation: Kent and Canterbury Hospital
Country: UK

Publications

  1. pmc Bone-specific alkaline phosphatase concentrations are less variable than those of parathyroid hormone in stable hemodialysis patients
    Sunita Sardiwal
    Clinical Biochemistry, East Kent Hospitals University NHS Foundation Trust, Kent and Canterbury Hospital, Canterbury, UK
    Kidney Int 82:100-5. 2012
  2. ncbi request reprint Diagnostic accuracy of cystatin C as a marker of kidney disease in patients with multiple myeloma: calculated glomerular filtration rate formulas are equally useful
    Edmund J Lamb
    Department of Clinical Biochemistry, East Kent Hospitals National Health Service Trust, Kent Hospital, Canterbury, UK
    Clin Chem 50:1848-51. 2004
  3. ncbi request reprint Serum calcium, phosphate, parathyroid hormone, albumin, aluminium and cholesterol achievement on replacement therapy (chapter 9)
    Edmund J Lamb
    Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, Kent and Canterbury Hospital, Canterbury, Kent CT1 3NG, UK
    Nephrol Dial Transplant 22:vii105-18. 2007
  4. ncbi request reprint Estimating kidney function in adults using formulae
    Edmund J Lamb
    Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, Canterbury, Kent, UK
    Ann Clin Biochem 42:321-45. 2005
  5. ncbi request reprint Susceptibility of glomerular filtration rate estimations to variations in creatinine methodology: a study in older patients
    Edmund J Lamb
    Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, Kent and Canterbury Hospital, Canterbury, Kent, UK
    Ann Clin Biochem 42:11-8. 2005
  6. ncbi request reprint Cardiac troponin I concentration is commonly increased in nondialysis patients with CKD: experience with a sensitive assay
    Edmund J Lamb
    Clinical Biochemistry, East Kent Hospitals NHS Trust, Canterbury, Kent
    Am J Kidney Dis 49:507-16. 2007
  7. ncbi request reprint United Kingdom guidelines for chronic kidney disease
    Edmund J Lamb
    Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, Canterbury, Kent, UK
    Scand J Clin Lab Invest Suppl 241:16-22. 2008
  8. doi request reprint How should proteinuria be detected and measured?
    Edmund J Lamb
    Department of Clinical Biochemistry, East Kent Hospital University NHS Foundation Trust, Canterbury, Kent, UK
    Ann Clin Biochem 46:205-17. 2009
  9. ncbi request reprint Topiramate increases biochemical risk of nephrolithiasis
    Edmund J Lamb
    Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, Kent and Canterbury Hospital, Canterbury, CT1 3NG, UK
    Ann Clin Biochem 41:166-9. 2004
  10. ncbi request reprint The significance of serum troponin T in patients with kidney disease: a review of the literature
    Edmund J Lamb
    Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, Kent and Canterbury Hospital, Canterbury CT1 3NG, UK
    Ann Clin Biochem 41:1-9. 2004

Collaborators

Detail Information

Publications43

  1. pmc Bone-specific alkaline phosphatase concentrations are less variable than those of parathyroid hormone in stable hemodialysis patients
    Sunita Sardiwal
    Clinical Biochemistry, East Kent Hospitals University NHS Foundation Trust, Kent and Canterbury Hospital, Canterbury, UK
    Kidney Int 82:100-5. 2012
    ....
  2. ncbi request reprint Diagnostic accuracy of cystatin C as a marker of kidney disease in patients with multiple myeloma: calculated glomerular filtration rate formulas are equally useful
    Edmund J Lamb
    Department of Clinical Biochemistry, East Kent Hospitals National Health Service Trust, Kent Hospital, Canterbury, UK
    Clin Chem 50:1848-51. 2004
  3. ncbi request reprint Serum calcium, phosphate, parathyroid hormone, albumin, aluminium and cholesterol achievement on replacement therapy (chapter 9)
    Edmund J Lamb
    Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, Kent and Canterbury Hospital, Canterbury, Kent CT1 3NG, UK
    Nephrol Dial Transplant 22:vii105-18. 2007
    ..The percentage of patients with cholesterol <5 mmol/l has increased significantly year-on-year in all three modalities...
  4. ncbi request reprint Estimating kidney function in adults using formulae
    Edmund J Lamb
    Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, Canterbury, Kent, UK
    Ann Clin Biochem 42:321-45. 2005
    ..In particular, the widespread adoption of estimated GFR reporting has refocused attention on the limitations of creatinine measurement and highlighted clinical situations in which the formulae are inadequate...
  5. ncbi request reprint Susceptibility of glomerular filtration rate estimations to variations in creatinine methodology: a study in older patients
    Edmund J Lamb
    Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, Kent and Canterbury Hospital, Canterbury, Kent, UK
    Ann Clin Biochem 42:11-8. 2005
    ..The influence of creatinine methodology on these estimates is not always appreciated. We have studied differences in creatinine methods and their influence on GFR estimation specifically in older people...
  6. ncbi request reprint Cardiac troponin I concentration is commonly increased in nondialysis patients with CKD: experience with a sensitive assay
    Edmund J Lamb
    Clinical Biochemistry, East Kent Hospitals NHS Trust, Canterbury, Kent
    Am J Kidney Dis 49:507-16. 2007
    ..cTn T (cTnT) concentration reportedly is increased more commonly than cTn I (cTnI). Using a sensitive cTnI assay, we studied cTnI concentrations in predialysis patients with CKD who did not have an acute coronary event...
  7. ncbi request reprint United Kingdom guidelines for chronic kidney disease
    Edmund J Lamb
    Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, Canterbury, Kent, UK
    Scand J Clin Lab Invest Suppl 241:16-22. 2008
    ..In autumn 2008, it is anticipated that the National Institute for Health and Clinical Excellence (NICE) will publish its clinical guidelines on CKD...
  8. doi request reprint How should proteinuria be detected and measured?
    Edmund J Lamb
    Department of Clinical Biochemistry, East Kent Hospital University NHS Foundation Trust, Canterbury, Kent, UK
    Ann Clin Biochem 46:205-17. 2009
    ....
  9. ncbi request reprint Topiramate increases biochemical risk of nephrolithiasis
    Edmund J Lamb
    Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, Kent and Canterbury Hospital, Canterbury, CT1 3NG, UK
    Ann Clin Biochem 41:166-9. 2004
    ..This report highlights the significantly increased metabolic risk of stone formation in patients receiving topiramate...
  10. ncbi request reprint The significance of serum troponin T in patients with kidney disease: a review of the literature
    Edmund J Lamb
    Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, Kent and Canterbury Hospital, Canterbury CT1 3NG, UK
    Ann Clin Biochem 41:1-9. 2004
    ..In the future, patients demonstrating this abnormality may be the target for more aggressive cardiac intervention, the advantages of which have been demonstrated in the non-uraemic population...
  11. ncbi request reprint Metabolic bone disease is present at diagnosis in patients with inflammatory bowel disease
    E J Lamb
    Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, Kent, UK
    Aliment Pharmacol Ther 16:1895-902. 2002
    ..To establish whether bone disease is present at diagnosis in inflammatory bowel disease and to identify contributory metabolic abnormalities...
  12. ncbi request reprint Estimation of glomerular filtration rate in older patients with chronic renal insufficiency: is the modification of diet in renal disease formula an improvement?
    Edmund J Lamb
    Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, Kent and Canterbury Hospital, Canterbury, Kent, United Kingdom
    J Am Geriatr Soc 51:1012-7. 2003
    ..To evaluate a new formula for glomerular filtration rate (GFR), derived from the Modification of Diet in Renal Disease (MDRD) study in older people...
  13. ncbi request reprint Renal tubular injury is present in acute inflammatory bowel disease prior to the introduction of drug therapy
    J S Fraser
    Department of Gastroenterology, East Kent Hospitals NHS Trust, Kent and Canterbury Hospital, Canterbury, Kent, UK
    Aliment Pharmacol Ther 15:1131-7. 2001
    ..Tubular proteins are not useful predictors of an adverse renal response to 5-ASA. Serum cystatin C may be an improved marker of glomerular filtration rate in this setting...
  14. doi request reprint Relationship of serum cystatin C to peritoneal and renal clearance measures in peritoneal dialysis: a cross-sectional study
    Michael P Delaney
    Department of Renal Medicine, East Kent Hospitals NHS Trust, Kent and Canterbury Hospital, Canterbury, Kent, UK
    Am J Kidney Dis 51:278-84. 2008
    ..Cystatin C is a low-molecular-weight protein used as a glomerular filtration rate marker. We investigated whether serum cystatin C concentration is related to peritoneal and renal clearances of creatinine and urea...
  15. ncbi request reprint Cystatin C improves the detection of mild renal dysfunction in older patients
    Shelagh E O'Riordan
    Department of Health Care of the Older Person, East Kent Hospitals NHS Trust, Kent and Canterbury Hospital, Canterbury CT1 3NG, UK
    Ann Clin Biochem 40:648-55. 2003
    ..In this study we have compared the diagnostic accuracy of a novel test of kidney disease, cystatin C, against these markers in older patients with a range of renal function...
  16. doi request reprint Estimating glomerular filtration rate: comparison of the CKD-EPI and MDRD equations in a large UK cohort with particular emphasis on the effect of age
    J L Carter
    Clinical Biochemistry, East Kent Hospitals University NHS Foundation Trust, Kent and Canterbury Hospital, Ethelbert Road, Canterbury, Kent CT1 3NG, UK
    QJM 104:839-47. 2011
    ..73 m(2)...
  17. ncbi request reprint Chronic kidney disease prevalence in a UK residential care home population
    Joanne L Carter
    Departments of Clinical Biochemistry, East Kent Hospitals NHS Trust, Canterbury, Kent, CT1 3NG, United Kingdom
    Nephrol Dial Transplant 23:1257-64. 2008
    ..Chronic kidney disease (CKD) is common ( approximately 30%) in non-institutionalized older people but little is known about the prevalence of CKD amongst older people living in residential care...
  18. doi request reprint Prognostic value of cardiac biomarkers for death in a non-dialysis chronic kidney disease population
    Susan Vickery
    Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, Kent and Canterbury Hospital, Canterbury, Kent, UK
    Nephrol Dial Transplant 23:3546-53. 2008
    ....
  19. pmc Variability of parathyroid hormone and other markers of bone mineral metabolism in patients receiving hemodialysis
    Clare Gardham
    Department of Clinical Biochemistry, East Kent Hospitals University NHS Foundation Trust, Kent and Canterbury Hospital, Ethelbert Road, Canterbury, Kent CT1 3NG, United Kingdom
    Clin J Am Soc Nephrol 5:1261-7. 2010
    ..The biologic variation of PTH and other bone mineral markers was measured in hemodialysis patients to better define their role in management...
  20. ncbi request reprint Does the ID-MS traceable MDRD equation work and is it suitable for use with compensated Jaffe and enzymatic creatinine assays?
    Susan Vickery
    Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, Kent and Canterbury Hospital, Canterbury, Kent CT1 3NG, UK
    Nephrol Dial Transplant 21:2439-45. 2006
    ....
  21. ncbi request reprint B-type natriuretic peptide (BNP) and amino-terminal proBNP in patients with CKD: relationship to renal function and left ventricular hypertrophy
    Susan Vickery
    Department of Clinical Biochemistry, East Kent Hospitals National Health Service Trust, Canterbury, Kent, UK
    Am J Kidney Dis 46:610-20. 2005
    ..The aim of the present study is to explore the relationship among circulating B-type natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) concentrations and clinical variables in a cohort of patients with CKD...
  22. ncbi request reprint Cardiac troponins and renal function in nondialysis patients with chronic kidney disease
    Nasir A Abbas
    Department of Renal Medicine, East Kent Hospitals NHS Trust, Canterbury, UK
    Clin Chem 51:2059-66. 2005
    ..There is little information on cardiac troponin concentrations in patients with chronic kidney disease (CKD) who have not commenced dialysis...
  23. doi request reprint Bone mineral metabolism and its relationship to kidney disease in a residential care home population: a cross-sectional study
    Joanne L Carter
    Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, Canterbury, Kent, UK
    Nephrol Dial Transplant 23:3554-65. 2008
    ..The present cross-sectional study assessed the relationship between markers of bone mineral metabolism and kidney function in a residential care home population...
  24. ncbi request reprint Renal tubular proteinuria in patients with irritable bowel syndrome
    A J O'Brien
    Department of Gastroenterology, East Kent Hospitals NHS Trust, Kent and Canterbury Hospital, Canterbury, Kent, UK
    Eur J Gastroenterol Hepatol 17:69-72. 2005
    ..We have previously demonstrated tubular protinuria in patients with inflammatory bowel disease. This study examined whether tubular proteinuria was a feature of IBS...
  25. ncbi request reprint Using the modification of diet in renal disease (MDRD) and Cockcroft and Gault equations to estimate glomerular filtration rate (GFR) in older people
    Edmund J Lamb
    Department of Clinical Biochemistry, Kent and Canterbury Hospital, Canterbury, Kent, UK
    Age Ageing 36:689-92. 2007
  26. ncbi request reprint Kidney function in older people: pathology, assessment and management
    Edmund J Lamb
    Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, Kent and Canterbury Hospital, Kent, Canterbury, UK
    Clin Chim Acta 334:25-40. 2003
    ..This could facilitate treatment aimed at reducing the progression of kidney disease in older people and improved management of its secondary complications...
  27. ncbi request reprint Stability of parathyroid hormone ex vivo in haemodialysis patients
    T K Teal
    Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, William Harvey Hospital, Ashford TN24 0LZ, UK
    Ann Clin Biochem 40:191-3. 2003
    ..Several studies have suggested that PTH is more stable in blood collected into a potassium edetate (EDTA) preservative...
  28. pmc Omeprazole and refractory hypomagnesaemia
    N Shabajee
    Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, Kent and Canterbury Hospital, Canterbury CT1 3NG
    BMJ 337:a425. 2008
  29. ncbi request reprint Thyroid function tests: often justified in the acutely ill
    E J Lamb
    Department of Clinical Biochemistry, East Kent Hospitals NHS Trust, Kent and Canterbury Hospital, Canterbury, UK
    Ann Clin Biochem 37:158-64. 2000
    ..Although NTI contributes to some cases of abnormal TSH levels, a significant number of TFT abnormalities are consistent with underlying thyroid abnormality requiring investigation/treatment...
  30. ncbi request reprint The cost of implementing UK guidelines for the management of chronic kidney disease
    Bernhard Klebe
    Department of Renal Medicine, Kent and Canterbury Hospital, East Kent Hospitals NHS Trust, and Computing Laboratory, University of Kent, Canterbury, Kent CT1 3NG, UK
    Nephrol Dial Transplant 22:2504-12. 2007
    ..In the UK, guidelines have been developed to facilitate case identification and management. Our aim was to estimate the annualized cost of implementation of the guidelines on newly identified CKD cases...
  31. ncbi request reprint Cardiac troponin T circulates in the free, intact form in patients with kidney failure
    Michael N Fahie-Wilson
    Department of Clinical Biochemistry, Southend Hospital, Westcliff on Sea, United Kingdom
    Clin Chem 52:414-20. 2006
    ....
  32. doi request reprint Circulating immunoreactive cardiac troponin forms determined by gel filtration chromatography after acute myocardial infarction
    Katharine J Bates
    Department of Clinical Biochemistry, East Kent Hospitals University NHS Foundation Trust, Kent and Canterbury Hospital, Canterbury, Kent, UK
    Clin Chem 56:952-8. 2010
    ..Whether cTn occurs in the circulation after AMI as ternary TIC, binary cTnI-TnC (IC) complexes, or free troponin forms has not been thoroughly investigated...
  33. ncbi request reprint Serum cystatin C may be a better marker of renal impairment than creatinine
    Edmund J Lamb
    J Am Geriatr Soc 51:1674; author reply 1674-5. 2003
  34. ncbi request reprint Effect of a compensated Jaffe creatinine method on the estimation of glomerular filtration rate
    Edmund J Lamb
    Ann Clin Biochem 42:160-1; author reply 161-2. 2005
  35. ncbi request reprint Use of amino-terminal pro-B-type natriuretic peptide to predict coronary disease
    Susan Vickery
    Am J Kidney Dis 47:194-5; author reply 195-6. 2006
  36. ncbi request reprint Estimating GFR with ID-MS traceable creatinine assays
    Edmund J Lamb
    Ann Clin Biochem 43:327. 2006
  37. ncbi request reprint Amino-terminal pro-brain natriuretic peptide to diagnose congestive heart failure in patients with impaired kidney function
    Edmund J Lamb
    J Am Coll Cardiol 48:1060-1; author reply 1061. 2006
  38. ncbi request reprint The influence of a cooked-meat meal on estimated glomerular filtration rate
    David J Preiss
    Wishaw General Hospital, 50 Netherton Street, Wishaw ML2 0DP, UK
    Ann Clin Biochem 44:35-42. 2007
    ..Previous reports have suggested that intake of large amounts of cooked meat can lead to a significant increase in serum creatinine concentration...
  39. ncbi request reprint Parathyroid hormone, kidney disease, evidence and guidelines
    Edmund J Lamb
    Ann Clin Biochem 44:1-4. 2007
  40. ncbi request reprint Challenging times in renal medicine: an opportunity for clinical biochemistry
    Edmund J Lamb
    Ann Clin Biochem 42:318-20. 2005
  41. ncbi request reprint Stability of cystatin C in urine
    Edmund J Lamb
    Ann Clin Biochem 41:421; author reply 421. 2004
  42. ncbi request reprint Stability of Bio-Intact (1-84) parathyroid hormone ex vivo in serum and EDTA plasma from hemodialysis patients
    Teresa K Teal
    Clin Chem 50:1713-4. 2004
  43. ncbi request reprint Spurious hypernatraemia and Citra-Lock
    Edmund J Lamb
    Ann Clin Biochem 44:579. 2007