Ian S D Roberts

Summary

Affiliation: John Radcliffe Hospital
Country: UK

Publications

  1. pmc Fatal case of sorafenib-associated idiosyncratic hepatotoxicity in the adjuvant treatment of a patient with renal cell carcinoma
    B P Fairfax
    Department of Oncology, Cancer and Haematology Centre, Churchill Hospital, Oxford OX3 7LJ, UK
    BMC Cancer 12:590. 2012
  2. ncbi request reprint Risk factors, graft fibrosis, and outcome: making the links
    Ian S D Roberts
    Department of Cellular Pathology, John Radcliffe Hospital, Oxford, UK
    Transplantation 83:679-80. 2007
  3. ncbi request reprint Subclinical rejection and borderline changes in early protocol biopsy specimens after renal transplantation
    Ian S D Roberts
    Department of Cellular Pathology, John Radcliffe Hospital, Headington, Oxford, United Kingdom
    Transplantation 77:1194-8. 2004
  4. doi request reprint Familial nephropathy and multiple exostoses with exostosin-1 (EXT1) gene mutation
    Ian S D Roberts
    Department of Cellular Pathology, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, United Kingdom
    J Am Soc Nephrol 19:450-3. 2008
  5. pmc Polyoma virus infection and urothelial carcinoma of the bladder following renal transplantation
    I S D Roberts
    Department of Cellular Pathology, John Radcliffe Hospital, Oxford, UK
    Br J Cancer 99:1383-6. 2008
  6. ncbi request reprint Accuracy of magnetic resonance imaging in determining cause of sudden death in adults: comparison with conventional autopsy
    I S D Roberts
    Department of Cellular Pathology, Oxford Radcliffe Hospitals, UK
    Histopathology 42:424-30. 2003
  7. doi request reprint Impact of immunosuppression on the incidence of early subclinical renal allograft rejection: implications for protocol biopsy policy
    Ian S D Roberts
    Department of Cellular Pathology, John Radcliffe Hospital, Headley Way, Headington, Oxford, UK
    Transpl Int 22:831-6. 2009
  8. doi request reprint The Oxford classification of IgA nephropathy: pathology definitions, correlations, and reproducibility
    Ian S D Roberts
    Department of Cellular Pathology, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK
    Kidney Int 76:546-56. 2009
  9. doi request reprint The pathology of depopulated bovine ureter xenografts utilized for vascular access in haemodialysis patients
    Gearoid T Kingston
    Department of Cellular Pathology, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Histopathology 55:154-60. 2009
  10. ncbi request reprint C4d deposition in early renal allograft protocol biopsies
    Dicken D H Koo
    Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Transplantation 78:398-403. 2004

Collaborators

Detail Information

Publications32

  1. pmc Fatal case of sorafenib-associated idiosyncratic hepatotoxicity in the adjuvant treatment of a patient with renal cell carcinoma
    B P Fairfax
    Department of Oncology, Cancer and Haematology Centre, Churchill Hospital, Oxford OX3 7LJ, UK
    BMC Cancer 12:590. 2012
    ..The SORCE trial is designed to investigate whether treatment with adjuvant sorafenib can reduce recurrence rates in this cohort...
  2. ncbi request reprint Risk factors, graft fibrosis, and outcome: making the links
    Ian S D Roberts
    Department of Cellular Pathology, John Radcliffe Hospital, Oxford, UK
    Transplantation 83:679-80. 2007
  3. ncbi request reprint Subclinical rejection and borderline changes in early protocol biopsy specimens after renal transplantation
    Ian S D Roberts
    Department of Cellular Pathology, John Radcliffe Hospital, Headington, Oxford, United Kingdom
    Transplantation 77:1194-8. 2004
    ..To determine the significance of early subclinical rejection, we reviewed protocol biopsies performed on days 7 and 28 during a 4-year period...
  4. doi request reprint Familial nephropathy and multiple exostoses with exostosin-1 (EXT1) gene mutation
    Ian S D Roberts
    Department of Cellular Pathology, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, United Kingdom
    J Am Soc Nephrol 19:450-3. 2008
    ..Similar glomerular basement membrane abnormalities could offer an explanation for both the renal ultrastructural changes and steroid-sensitive nephrotic syndrome...
  5. pmc Polyoma virus infection and urothelial carcinoma of the bladder following renal transplantation
    I S D Roberts
    Department of Cellular Pathology, John Radcliffe Hospital, Oxford, UK
    Br J Cancer 99:1383-6. 2008
    ..Its presence in all tumour cells in one patient transplanted in the PVN era might suggest a possible role in tumorigenesis in that case...
  6. ncbi request reprint Accuracy of magnetic resonance imaging in determining cause of sudden death in adults: comparison with conventional autopsy
    I S D Roberts
    Department of Cellular Pathology, Oxford Radcliffe Hospitals, UK
    Histopathology 42:424-30. 2003
    ..To determine the accuracy and define the limitations of post mortem magnetic resonance imaging (MRI) in determining the cause of sudden death in adults...
  7. doi request reprint Impact of immunosuppression on the incidence of early subclinical renal allograft rejection: implications for protocol biopsy policy
    Ian S D Roberts
    Department of Cellular Pathology, John Radcliffe Hospital, Headley Way, Headington, Oxford, UK
    Transpl Int 22:831-6. 2009
    ..New immunosuppressive regimens may reduce subclinical in addition to clinical rejection-frequency, suggesting that the relative benefit of early protocol biopsies in detecting SCR is also reduced...
  8. doi request reprint The Oxford classification of IgA nephropathy: pathology definitions, correlations, and reproducibility
    Ian S D Roberts
    Department of Cellular Pathology, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK
    Kidney Int 76:546-56. 2009
    ..Our methodology, translating a strong evidence-based dataset into a working format, is a model for developing classifications of other types of renal disease...
  9. doi request reprint The pathology of depopulated bovine ureter xenografts utilized for vascular access in haemodialysis patients
    Gearoid T Kingston
    Department of Cellular Pathology, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Histopathology 55:154-60. 2009
    ..The aim was to undertake the first systematic review of the histopathology of bovine ureter xenografts (n = 25) utilized for haemodialysis vascular access in humans...
  10. ncbi request reprint C4d deposition in early renal allograft protocol biopsies
    Dicken D H Koo
    Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Transplantation 78:398-403. 2004
    ..In this study, we examined C4d deposition in protocol biopsies obtained irrespective of clinical status...
  11. doi request reprint Detection of polyomavirus BK reactivation after renal transplantation using an intensive decoy cell surveillance program is cost-effective
    Aron Chakera
    Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
    Transplantation 92:1018-23. 2011
    ..We present the outcomes from an early intensive BKV surveillance program using decoy cell detection for initial screening starting 2 weeks after transplantation...
  12. ncbi request reprint Thrombotic microangiopathy in advanced prostatic carcinoma
    Suzanne M Biers
    Department of Urology, Churchill Hospital, Oxford, United Kingdom
    Urology 63:380-2. 2004
    ..Postmortem examination revealed the renal failure to have been due to severe thrombotic microangiopathy...
  13. doi request reprint High risk medicolegal autopsies: is a full postmortem examination necessary?
    Eve Patricia Fryer
    Department of Cellular Pathology, John Radcliffe Hospital, Oxford, UK
    J Clin Pathol 66:1-7. 2013
    ..In this study, we review and validate this protocol...
  14. doi request reprint Immunostaining findings in IgA nephropathy: correlation with histology and clinical outcome in the Oxford classification patient cohort
    Shubha S Bellur
    Department of Cellular Pathology, John Radcliffe Hospital, Oxford, UK
    Nephrol Dial Transplant 26:2533-6. 2011
    ..Here, we investigate the potential clinical significance of immunostaining data...
  15. doi request reprint Evaluation of diagnostic strategies for bladder cancer using computed tomography (CT) urography, flexible cystoscopy and voided urine cytology: results for 778 patients from a hospital haematuria clinic
    Christopher G T Blick
    Department of Urology, The Churchill Hospital, Oxford, UK
    BJU Int 110:84-94. 2012
    ..The present study also shows that the diagnostic accuracy of voided urine cytology is too low to justify its continuing use in a haematuria clinic using CT urography and flexible cystoscopy...
  16. doi request reprint Simultaneous necrotizing glomerulonephritis and Hodgkin's lymphoma: a case report and review of the literature
    Thomas D Barbour
    Oxford Kidney Unit, Churchill Hospital, Oxford Radcliffe Hospitals NHS Trust, Oxford, UK
    Nephrol Dial Transplant 26:3403-8. 2011
    ..Two years later, recrudescent lymphadenopathy was shown to be Hodgkin's lymphoma, but renal disease did not recur...
  17. pmc Post-mortem imaging as an alternative to autopsy in the diagnosis of adult deaths: a validation study
    Ian S D Roberts
    Department of Cellular Pathology, John Radcliffe Hospital, Oxford, UK
    Lancet 379:136-42. 2012
    ..Imaging has potential, but its accuracy is unknown. We aimed to identify the accuracy of post-mortem CT and MRI compared with full autopsy in a large series of adult deaths...
  18. ncbi request reprint Rapidly progressive irreversible renal failure in patients with pancreatic insufficiency
    Peter Hill
    Oxford Kidney Unit, The Churchill, The Oxford Radcliffe Hospitals NHS Trust, Oxford, UK
    Am J Kidney Dis 42:842-5. 2003
  19. doi request reprint Laparoscopic high-intensity focused ultrasound for renal tumours: a proof of concept study
    Robert W Ritchie
    Department of Urology, Churchill Hospital, Oxford, UK
    BJU Int 107:1290-6. 2011
    ..Successful and accurate tumour destruction was demonstrated, paving the way for further clinical trials, subject to device modifications...
  20. doi request reprint Association of long-term administration of the survivin mRNA-targeted antisense oligonucleotide LY2181308 with reversible kidney injury in a patient with metastatic melanoma
    William G Herrington
    Churchill Hospital, Oxford, UK
    Am J Kidney Dis 57:300-3. 2011
    ....
  21. doi request reprint The handling and sampling of radical prostatectomy specimens for reporting and research: the Oxford approach
    Pelvender Singh Gill
    Department of Cellular Pathology and Oxford Biomedical Research Centre, Oxford University Hospitals NHS Trust, Oxford, UK
    J Clin Pathol 65:1057-61. 2012
    ....
  22. doi request reprint An adult Xp11.2 translocation renal carcinoma showing response to treatment with sunitinib
    Thinn P Pwint
    Medical Oncology Unit, Churchill Hospital, Oxford, United Kingdom
    Urol Oncol 29:821-4. 2011
    ..It remains unclear how resistance to sunitinib develops, but the results to date support further evaluation of sunitinib in cases of translocation RCC...
  23. ncbi request reprint Contrast-enhanced ultrasound assessment of tissue response to high-intensity focused ultrasound
    James E Kennedy
    Department of Urology, Churchill Hospital, Oxford, UK
    Ultrasound Med Biol 30:851-4. 2004
    ..Observed changes were seen to correlate well with the ablated volume on histologic evaluation of the treated volume. This is the first time that this imaging technique has been reported in this setting...
  24. doi request reprint An unusual cause of acute renal failure with volume depletion due to renal losses
    Lin Chong
    Wessex Renal and Transplant Service, Queen Alexandra Hospital, Portsmouth, UK
    Am J Kidney Dis 52:366-9. 2008
  25. ncbi request reprint Acute renal failure secondary to oxalosis in a recipient of a simultaneous kidney-pancreas transplant: was mycophenolate the cause?
    Alireza Hamidian Jahromi
    Renal Transplant Unit, St George s Hospital, London SW17 0QT, UK
    Nephrol Dial Transplant 23:2409-11. 2008
  26. ncbi request reprint TGF-beta1 in chronic allograft nephropathy following renal transplantation
    Shelley Harris
    The Renal Research Laboratories, Manchester Institute of Nephrology and Transplantation, Manchester Royal Infirmary, Manchester, UK
    J Nephrol 20:177-85. 2007
    ....
  27. ncbi request reprint Diagnosis of acute renal allograft rejection: evaluation of the Banff 97 Guidelines for Slide Preparation
    Gerard P McCarthy
    Department of Histopathology, Manchester Royal Infirmary, Manchester, United Kingdom
    Transplantation 73:1518-21. 2002
    ..In this study, we examine the validity of the Banff '97 recommendations and determine how widely these recommendations are applied...
  28. pmc Urine cytology screening for polyoma virus infection following renal transplantation: the Oxford experience
    Thomas P Thamboo
    Department of Pathology, National University of Singapore, National University Hospital, Singapore
    J Clin Pathol 60:927-30. 2007
    ..To review the first year of a monthly urine cytology screening service, introduced to identify renal transplant patients at risk of polyoma virus nephropathy (PVN), at an early, potentially treatable, stage...
  29. pmc Implementation of the 2005 Coroners Rules Amendments: a survey of practice in England and Wales
    Russell J Delaney
    Forensic Pathology Unit, Leicester Royal Infirmary, Leicester, UK
    J Clin Pathol 60:419-21. 2007
    ..These principally cover the retention of tissues from autopsies and their subsequent disposal. This study assesses regional variations in the interpretations of the amendments, and their impact on local autopsy practice in Oxford...
  30. ncbi request reprint Inhibitory smads and tgf-Beta signaling in glomerular cells
    Mario Schiffer
    Division of Nephrology, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Am Soc Nephrol 13:2657-66. 2002
    ..These data indicate an important role for Smad6 and Smad7 in glomerular cells in vivo that could be important for the cell homeostasis in physiologic and pathologic conditions...
  31. ncbi request reprint Inhibition of chronic vascular rejection by donor-specific blood transfusion is associated with a reduction in transforming growth factor-beta1 expression
    Emma A O Shittu
    Immunology Research Group, School of Biological Sciences, and Department of Medicine, University of Manchester, Manchester, United Kingdom
    Transplantation 73:1573-81. 2002
    ..The present study investigates in more depth the underlying mechanisms involved in the subsequent prolongation of allograft survival and inhibition of CVR by DST...
  32. ncbi request reprint Controlled prospective trial of prednisolone and cytotoxics in progressive IgA nephropathy
    Francis W Ballardie
    Department of Nephrology, Royal Infirmary and University, Manchester, United Kingdom
    J Am Soc Nephrol 13:142-8. 2002
    ....