Constantinos Christodoulides

Summary

Affiliation: John Radcliffe Hospital
Country: UK

Publications

  1. ncbi Adipogenesis and WNT signalling
    Constantinos Christodoulides
    Institute of Metabolic Science, MRC Centre for Obesity and Associated Diseases, Biochemistry, University of Cambridge, Addenbrooke s Hospital, Cambridge, CB2 0QQ, UK
    Trends Endocrinol Metab 20:16-24. 2009
  2. ncbi PPARs and adipocyte function
    Constantinos Christodoulides
    Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford OX3 7LJ, UK
    Mol Cell Endocrinol 318:61-8. 2010
  3. ncbi Dact1, a nutritionally regulated preadipocyte gene, controls adipogenesis by coordinating the Wnt/beta-catenin signaling network
    Claire Lagathu
    Institute of Metabolic Science Metabolic Research Laboratories and Department of Clinical Biochemistry, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Diabetes 58:609-19. 2009
  4. ncbi ETO/MTG8 is an inhibitor of C/EBPbeta activity and a regulator of early adipogenesis
    Justin J Rochford
    Department of Clinical Biochemistry, University of Cambridge, Box 232, Level 4, Addenbrooke s Hospital, Hills Rd, Cambridge CB2 2QR, United Kingdom
    Mol Cell Biol 24:9863-72. 2004
  5. ncbi The Wnt antagonist Dickkopf-1 and its receptors are coordinately regulated during early human adipogenesis
    Constantinos Christodoulides
    Department of Clinical Biochemistry, University of Cambridge, Addenbrooke s Hospital, Hills Road, Cambridge, CB2 2QR, UK
    J Cell Sci 119:2613-20. 2006
  6. ncbi Serum levels of retinol-binding protein 4 and adiponectin in women with polycystic ovary syndrome: associations with visceral fat but no evidence for fat mass-independent effects on pathogenesis in this condition
    Thomas M Barber
    Diabetes Research Laboratories, Oxford Centre for Diabetes, Endocrinology, and Metabolism, Churchill Hospital, Old Road, Headington, Oxford, United Kingdom
    J Clin Endocrinol Metab 93:2859-65. 2008
  7. ncbi Current treatment protocols can offer a normal or near-normal quality of life in the majority of patients with non-functioning pituitary adenomas
    Cristina Capatina
    Department of Endocrinology, Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford, UK
    Clin Endocrinol (Oxf) 78:86-93. 2013
  8. ncbi Role of the POZ zinc finger transcription factor FBI-1 in human and murine adipogenesis
    Matthias Laudes
    Department of Clinical Biochemistry, University of Cambridge, Addenbrooke s Hospital, Hills Road, Cambridge CB2 2QR, United Kingdom
    J Biol Chem 279:11711-8. 2004
  9. ncbi Circulating fibroblast growth factor 21 is induced by peroxisome proliferator-activated receptor agonists but not ketosis in man
    Constantinos Christodoulides
    Oxford Centre for Diabetes, Endocrinology, and Metabolism, Churchill Hospital, Oxford OX3 7LJ, United Kingdom
    J Clin Endocrinol Metab 94:3594-601. 2009

Collaborators

Detail Information

Publications9

  1. ncbi Adipogenesis and WNT signalling
    Constantinos Christodoulides
    Institute of Metabolic Science, MRC Centre for Obesity and Associated Diseases, Biochemistry, University of Cambridge, Addenbrooke s Hospital, Cambridge, CB2 0QQ, UK
    Trends Endocrinol Metab 20:16-24. 2009
    ..Manipulating the WNT pathway to alter adipose cellular makeup, therefore, constitutes an attractive drug-development target to combat obesity-associated metabolic complications...
  2. ncbi PPARs and adipocyte function
    Constantinos Christodoulides
    Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford OX3 7LJ, UK
    Mol Cell Endocrinol 318:61-8. 2010
    ..In this review we discuss the characteristics of PPARs and the role of the different isotypes in adipocyte biology...
  3. ncbi Dact1, a nutritionally regulated preadipocyte gene, controls adipogenesis by coordinating the Wnt/beta-catenin signaling network
    Claire Lagathu
    Institute of Metabolic Science Metabolic Research Laboratories and Department of Clinical Biochemistry, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Diabetes 58:609-19. 2009
    ..Here, we identify the Wnt modulator Dapper1/Frodo1 (Dact1) as a new preadipocyte gene involved in the regulation of murine and human adipogenesis...
  4. ncbi ETO/MTG8 is an inhibitor of C/EBPbeta activity and a regulator of early adipogenesis
    Justin J Rochford
    Department of Clinical Biochemistry, University of Cambridge, Box 232, Level 4, Addenbrooke s Hospital, Hills Rd, Cambridge CB2 2QR, United Kingdom
    Mol Cell Biol 24:9863-72. 2004
    ..These findings define, for the first time, a molecular role for ETO in normal physiology as an inhibitor of C/EBPbeta and a novel regulator of early adipogenesis...
  5. ncbi The Wnt antagonist Dickkopf-1 and its receptors are coordinately regulated during early human adipogenesis
    Constantinos Christodoulides
    Department of Clinical Biochemistry, University of Cambridge, Addenbrooke s Hospital, Hills Road, Cambridge, CB2 2QR, UK
    J Cell Sci 119:2613-20. 2006
    ..Given the public health importance of disorders of adipose mass, further knowledge of the pathways involved specifically in human adipocyte differentiation might ultimately be of clinical relevance...
  6. ncbi Serum levels of retinol-binding protein 4 and adiponectin in women with polycystic ovary syndrome: associations with visceral fat but no evidence for fat mass-independent effects on pathogenesis in this condition
    Thomas M Barber
    Diabetes Research Laboratories, Oxford Centre for Diabetes, Endocrinology, and Metabolism, Churchill Hospital, Old Road, Headington, Oxford, United Kingdom
    J Clin Endocrinol Metab 93:2859-65. 2008
    ..Insulin resistance, which associates with levels of retinol-binding protein 4 (RBP4) and adiponectin, is implicated in the development of polycystic ovary syndrome (PCOS)...
  7. ncbi Current treatment protocols can offer a normal or near-normal quality of life in the majority of patients with non-functioning pituitary adenomas
    Cristina Capatina
    Department of Endocrinology, Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford, UK
    Clin Endocrinol (Oxf) 78:86-93. 2013
    ..In view of the discordant findings and the advances in the management of these subjects, we aimed to evaluate the QoL in patients with NFA followed up in a tertiary endocrine UK referral centre...
  8. ncbi Role of the POZ zinc finger transcription factor FBI-1 in human and murine adipogenesis
    Matthias Laudes
    Department of Clinical Biochemistry, University of Cambridge, Addenbrooke s Hospital, Hills Road, Cambridge CB2 2QR, United Kingdom
    J Biol Chem 279:11711-8. 2004
    ....
  9. ncbi Circulating fibroblast growth factor 21 is induced by peroxisome proliferator-activated receptor agonists but not ketosis in man
    Constantinos Christodoulides
    Oxford Centre for Diabetes, Endocrinology, and Metabolism, Churchill Hospital, Oxford OX3 7LJ, United Kingdom
    J Clin Endocrinol Metab 94:3594-601. 2009
    ..FGF21 is also a PPAR gamma target gene in mouse adipose tissue. Little information is available on FGF21 functions in humans...