Iain Chalmers

Summary

Affiliation: James Lind Library
Country: UK

Publications

  1. ncbi request reprint Commentary: the 1944 patulin trial: the first properly controlled multicentre trial conducted under the aegis of the British Medical Research Council
    Iain Chalmers
    James Lind Library, James Lind Initiative, Summertown Pavilion, Middle Way, Oxford OX2 7LG, UK
    Int J Epidemiol 33:253-60. 2004
  2. pdf Biased underreporting of research is unethical and should be outlawed
    Iain Chalmers
    James Lind Library, Oxford, England
    Z Arztl Fortbild Qualitatssich 100:531-5. 2006
  3. pmc Data sharing among data monitoring committees and responsibilities to patients and science
    Iain Chalmers
    James Lind Initiative, Summertown Pavilion, Middle Way, Oxford OX2 7LG, UK
    Trials 14:102. 2013
  4. ncbi request reprint Fisher and Bradford Hill: theory and pragmatism?
    Iain Chalmers
    James Lind Library, James Lind Initiative, Summertown Pavilion, Middle Way, Oxford OX2 7LG, UK
    Int J Epidemiol 32:922-4; discussion 945-8. 2003
  5. ncbi request reprint Better information systems are needed to help patients and clinicians integrate clinical research within everyday clinical practice
    Iain Chalmers
    James Lind Initiative, Oxford, UK
    Otolaryngol Head Neck Surg 137:S69-71. 2007
  6. pmc Joseph Asbury Bell and the birth of randomized trials
    Iain Chalmers
    J R Soc Med 100:287-93. 2007
  7. ncbi request reprint What are the implications of optimism bias in clinical research?
    Iain Chalmers
    James Lind Library, Summertown Pavilion, Oxford OX2 7LG, UK
    Lancet 367:449-50. 2006
  8. pmc From optimism to disillusion about commitment to transparency in the medico-industrial complex
    Iain Chalmers
    J R Soc Med 99:337-41. 2006
  9. pmc Role of systematic reviews in detecting plagiarism: case of Asim Kurjak
    Iain Chalmers
    James Lind Library, Oxford OX2 7LG
    BMJ 333:594-6. 2006
  10. ncbi request reprint The James Lind Library: explaining and illustrating the evolution of fair tests of medical treatments
    I Chalmers
    James Lind Initiative, Oxford, UK
    J R Coll Physicians Edinb 38:259-64. 2008

Collaborators

Detail Information

Publications47

  1. ncbi request reprint Commentary: the 1944 patulin trial: the first properly controlled multicentre trial conducted under the aegis of the British Medical Research Council
    Iain Chalmers
    James Lind Library, James Lind Initiative, Summertown Pavilion, Middle Way, Oxford OX2 7LG, UK
    Int J Epidemiol 33:253-60. 2004
    ..This status is reflected in the International Journal of Epidemiology's reproduction of the full text of the trial report in this issue of the journal...
  2. pdf Biased underreporting of research is unethical and should be outlawed
    Iain Chalmers
    James Lind Library, Oxford, England
    Z Arztl Fortbild Qualitatssich 100:531-5. 2006
    ..It is necessary to register all clinical trials publicly, at inception. Drug companies should be forced to publish all results, regardless of outcome...
  3. pmc Data sharing among data monitoring committees and responsibilities to patients and science
    Iain Chalmers
    James Lind Initiative, Summertown Pavilion, Middle Way, Oxford OX2 7LG, UK
    Trials 14:102. 2013
    ....
  4. ncbi request reprint Fisher and Bradford Hill: theory and pragmatism?
    Iain Chalmers
    James Lind Library, James Lind Initiative, Summertown Pavilion, Middle Way, Oxford OX2 7LG, UK
    Int J Epidemiol 32:922-4; discussion 945-8. 2003
  5. ncbi request reprint Better information systems are needed to help patients and clinicians integrate clinical research within everyday clinical practice
    Iain Chalmers
    James Lind Initiative, Oxford, UK
    Otolaryngol Head Neck Surg 137:S69-71. 2007
    ..My experiences illustrate why I believe better information systems are needed if clinical research is to become integrated in everyday clinical practice, for the benefit of both patients and clinicians...
  6. pmc Joseph Asbury Bell and the birth of randomized trials
    Iain Chalmers
    J R Soc Med 100:287-93. 2007
  7. ncbi request reprint What are the implications of optimism bias in clinical research?
    Iain Chalmers
    James Lind Library, Summertown Pavilion, Oxford OX2 7LG, UK
    Lancet 367:449-50. 2006
  8. pmc From optimism to disillusion about commitment to transparency in the medico-industrial complex
    Iain Chalmers
    J R Soc Med 99:337-41. 2006
  9. pmc Role of systematic reviews in detecting plagiarism: case of Asim Kurjak
    Iain Chalmers
    James Lind Library, Oxford OX2 7LG
    BMJ 333:594-6. 2006
  10. ncbi request reprint The James Lind Library: explaining and illustrating the evolution of fair tests of medical treatments
    I Chalmers
    James Lind Initiative, Oxford, UK
    J R Coll Physicians Edinb 38:259-64. 2008
    ..A multinational, multilingual editorial team oversees the development of the website, which currently receives tens of thousands of visitors every month...
  11. pmc Descriptive survey of non-commercial randomised controlled trials in the United Kingdom, 1980-2002
    Iain Chalmers
    UK Randomised Controlled Trial Registration Project, UK Cochrane Centre, Oxford OX2 7LG
    BMJ 327:1017. 2003
    ..To describe the characteristics of randomised controlled trials supported by the main non-commercial sources of funding in the United Kingdom between 1980 and 2002...
  12. pmc Reports of clinical trials should begin and end with up-to-date systematic reviews of other relevant evidence: a status report
    Mike Clarke
    UK Cochrane Centre, NHS R and D Programme, Summertown Pavilion, Middle Way, Oxford OX2 7LG, UK
    J R Soc Med 100:187-90. 2007
    ..In the current study, we assess whether there had been progress in this respect in 2005 and also investigate the extent to which reports begin by referring to systematic reviews providing the justification for the new research reported...
  13. ncbi request reprint Why fair tests are needed: a brief history
    Iain Chalmers
    James Lind Library, Oxford, UK
    Evid Based Med 11:67-8. 2006
  14. doi request reprint How to increase value and reduce waste when research priorities are set
    Iain Chalmers
    James Lind Initiative, Oxford, UK Electronic address
    Lancet 383:156-65. 2014
    ..Research funders have primary responsibility for reductions in waste resulting from decisions about what research to do...
  15. ncbi request reprint Why fair tests are needed: a brief history
    Iain Chalmers
    James Lind Library, Oxford, England, UK
    ACP J Club 145:A8-9. 2006
  16. ncbi request reprint Discussion sections in reports of controlled trials published in general medical journals
    Mike Clarke
    UK Cochrane Centre, National Health Service Research and Development Programme, Summertown Pavilion, Middle Way, Oxford OX2 7LG, England
    JAMA 287:2799-801. 2002
    ..We assessed the extent to which reports of controlled trials published in the same 5 journals discussed new results in light of the totality of evidence from other controlled trials...
  17. doi request reprint No surgical innovation without evaluation: the IDEAL recommendations
    Peter McCulloch
    Nuffield Department of Surgery, University of Oxford, Oxford, UK
    Lancet 374:1105-12. 2009
    ..Achievement of improved design, conduct, and reporting of surgical research will need concerted action by editors, funders of health care and research, regulatory bodies, and professional societies...
  18. pmc Survey of claims of no effect in abstracts of Cochrane reviews
    Phil Alderson
    UK Cochrane Centre, NHS Research and Development Programme, Oxford OX2 7LG
    BMJ 326:475. 2003
  19. ncbi request reprint A brief history of research synthesis
    Iain Chalmers
    U K Cochrane Centre, Summertown Pavilion, Middle Way, Oxford OX2 7LG, UK
    Eval Health Prof 25:12-37. 2002
    ....
  20. doi request reprint The origins, evolution, and future of The Cochrane Database of Systematic Reviews
    Mark Starr
    Update Software Ltd, Oxford OX2 7LG, UK
    Int J Technol Assess Health Care 25:182-95. 2009
    ..Although CDSR has become widely cited, it must continue to evolve in the light of technological and methodological developments, and in response to the needs of people making decisions about health care...
  21. ncbi request reprint In the dark: drug companies should be forced to publish all the results of clinical trials
    Iain Chalmers
    The James Lind Library, USA
    New Sci 181:19. 2004
  22. ncbi request reprint Why fair tests are needed: a brief history
    Iain Chalmers
    Evid Based Nurs 10:4-5. 2007
  23. doi request reprint Medical justice for undocumented migrants
    Frank Arnold
    Lancet 371:201. 2008
  24. doi request reprint Human rights and professional responsibilities in health care and education
    Iain Chalmers
    Eur J Dent Educ 12:11-6. 2008
  25. ncbi request reprint [The disciple not far behind master Cochrane]
    Lars Werko
    Lakartidningen 105:1511. 2008
  26. ncbi request reprint Clinical trials in NZ: does anybody know what's going on?
    Andrew Jull
    N Z Med J 115:U269. 2002
  27. ncbi request reprint TGN1412 and The Lancet's solicitation of reports of phase I trials
    Iain Chalmers
    Lancet 368:2206-7. 2006
  28. doi request reprint Historians and the history of medicine
    Iain Chalmers
    Lancet 372:1632. 2008
  29. ncbi request reprint Iain Chalmers: maverick master of medical evidence
    Geoff Watts
    Lancet 368:2203. 2006
  30. pmc When are randomised trials unnecessary? Picking signal from noise
    Paul Glasziou
    Centre for Evidence Based Medicine, Department of Primary Health Care, University of Oxford, Oxford OX3 7LF
    BMJ 334:349-51. 2007
    ..This model may help to reduce controversy about evidence for treatments whose effects are so dramatic that randomised trials are unnecessary...
  31. pmc How to formulate research recommendations
    Polly Brown
    BMJ Publishing Group, London WC1H 9JR
    BMJ 333:804-6. 2006
  32. ncbi request reprint Cardiotocography v Doppler auscultation. All unbiased comparative studies should be published
    Iain Chalmers
    BMJ 324:483-5. 2002
  33. ncbi request reprint Academic recognition of critical appraisal and systematic reviews in British postgraduate medical education
    Phil Alderson
    Med Educ 37:386. 2003
  34. pmc The James Lind Initiative
    Iain Chalmers
    J R Soc Med 96:575-6. 2003
  35. ncbi request reprint Lessons for research ethics committees
    Iain Chalmers
    Lancet 359:174. 2002
  36. pmc Assessing the quality of research
    Paul Glasziou
    Department of Primary Health Care, University of Oxford, Oxford OX3 7LF
    BMJ 328:39-41. 2004
  37. pmc Academic medicine: time for reinvention: MRC aims to give NHS evidence from randomised clinical trials
    Colin Blakemore
    BMJ 328:49; discussion 49. 2004
  38. ncbi request reprint Public confusion about treatment effects
    Iain Chalmers
    Lancet 363:1078-9. 2004
  39. pmc Government regulation is needed to prevent biased under-reporting of clinical trials
    Iain Chalmers
    BMJ 329:462. 2004
  40. pmc A field guide to experts
    Andrew D Oxman
    Informed Choice Research Department, Norwegian Health Services Research Centre, PO Box 0130, Oslo, Norway
    BMJ 329:1460-3. 2004
  41. ncbi request reprint Academia's failure to support systematic reviews
    Iain Chalmers
    Lancet 365:469. 2005
  42. ncbi request reprint Bill Silverman: a personal appreciation
    Iain Chalmers
    Paediatr Perinat Epidemiol 19:82-5. 2005
  43. ncbi request reprint Is the NHS willing to help clinicians and patients reduce uncertainties about the effects of treatments?
    Rorert Chalmers
    Dermatology Centre, Hope Hospital, Salford, Manchester
    Clin Med 5:230-4. 2005
    ..The NHS needs to listen to its users, ie the patients, and to its clinical staff, and to encourage them to engage in research to help reduce those uncertainties...
  44. pmc Are experimental treatments for cancer in children superior to established treatments? Observational study of randomised controlled trials by the Children's Oncology Group
    Ambuj Kumar
    Department of Interdisciplinary Oncology, H Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, FL 33612, USA
    BMJ 331:1295. 2005
    ....
  45. ncbi request reprint Are any of the criticisms of the CNEP trial true?
    Edmund Hey
    Lancet 367:1032-3. 2006
  46. ncbi request reprint Preventing scientific misconduct
    Iain Chalmers
    Lancet 368:450. 2006
  47. ncbi request reprint The landscape and lexicon of blinding in randomized trials
    Kenneth F Schulz
    Family Health International, Box 13950, Research Triangle Park, NC 27709, USA
    Ann Intern Med 136:254-9. 2002