David A Harrison

Summary

Affiliation: Intensive Care National Audit and Research Centre
Country: UK

Publications

  1. ncbi request reprint Winter excess mortality in intensive care in the UK: an analysis of outcome adjusted for patient case mix and unit workload
    David A Harrison
    Intensive Care National Audit and Research Centre, Tavistock House, Tavistock Square, WC1H 9HR London, UK
    Intensive Care Med 30:1900-7. 2004
  2. pmc Characteristics and outcome for admissions to adult, general critical care units with acute severe asthma: a secondary analysis of the ICNARC Case Mix Programme Database
    Dheeraj Gupta
    Department of Respiratory Medicine, Birmingham Heartlands Solihull NHS Trust, Birmingham, UK
    Crit Care 8:R112-21. 2004
  3. pmc Case mix, outcome and length of stay for admissions to adult, general critical care units in England, Wales and Northern Ireland: the Intensive Care National Audit & Research Centre Case Mix Programme Database
    David A Harrison
    Intensive Care National Audit and Research Centre, London, UK
    Crit Care 8:R99-111. 2004
  4. pmc Case mix, outcome, and activity for admissions to UK critical care units with severe acute pancreatitis: a secondary analysis of the ICNARC Case Mix Programme Database
    David A Harrison
    Intensive Care National Audit and Research Centre ICNARC, Tavistock House, Tavistock Square, London WC1H 9HR, UK
    Crit Care 11:S1. 2007
  5. doi request reprint Post hoc insights from PAC-Man--the U.K. pulmonary artery catheter trial
    Sheila E Harvey
    Medical Statistics Unit, London School of Hygiene and Tropical Medicine, London, UK
    Crit Care Med 36:1714-21. 2008
  6. ncbi request reprint Recalibration of risk prediction models in a large multicenter cohort of admissions to adult, general critical care units in the United Kingdom
    David A Harrison
    Intensive Care National Audit and Research Centre, London, UK
    Crit Care Med 34:1378-88. 2006
  7. doi request reprint The effects of critical care outreach services before and after critical care: a matched-cohort analysis
    David A Harrison
    Intensive Care National Audit and Research Centre, Tavistock House, Tavistock Square, London WC1H 9HR, UK
    J Crit Care 25:196-204. 2010
  8. ncbi request reprint A new measure of acute physiological derangement for patients with exacerbations of obstructive airways disease: the COPD and Asthma Physiology Score
    Martin J Wildman
    Department of Respiratory Medicine, Northern General Hospital, Herries Road, Sheffield S5 7AU, UK
    Respir Med 101:1994-2002. 2007
  9. pmc Case mix, outcomes and comparison of risk prediction models for admissions to adult, general and specialist critical care units for head injury: a secondary analysis of the ICNARC Case Mix Programme Database
    Jonathan A Hyam
    Department of Neurosurgery, Charing Cross Hospital, London, UK
    Crit Care 10:S2. 2006
  10. ncbi request reprint A new risk prediction model for critical care: the Intensive Care National Audit & Research Centre (ICNARC) model
    David A Harrison
    Intensive Care National Audit and Research Centre ICNARC, London, UK
    Crit Care Med 35:1091-8. 2007

Detail Information

Publications23

  1. ncbi request reprint Winter excess mortality in intensive care in the UK: an analysis of outcome adjusted for patient case mix and unit workload
    David A Harrison
    Intensive Care National Audit and Research Centre, Tavistock House, Tavistock Square, WC1H 9HR London, UK
    Intensive Care Med 30:1900-7. 2004
    ..To investigate whether mortality in UK intensive care units is higher in winter than in non-winter and to explore the importance of variations in case mix and increased pressure on ICUs...
  2. pmc Characteristics and outcome for admissions to adult, general critical care units with acute severe asthma: a secondary analysis of the ICNARC Case Mix Programme Database
    Dheeraj Gupta
    Department of Respiratory Medicine, Birmingham Heartlands Solihull NHS Trust, Birmingham, UK
    Crit Care 8:R112-21. 2004
    ....
  3. pmc Case mix, outcome and length of stay for admissions to adult, general critical care units in England, Wales and Northern Ireland: the Intensive Care National Audit & Research Centre Case Mix Programme Database
    David A Harrison
    Intensive Care National Audit and Research Centre, London, UK
    Crit Care 8:R99-111. 2004
    ..The paper also describes the case mix, outcome and activity of the admissions in the Case Mix Programme Database (CMPD)...
  4. pmc Case mix, outcome, and activity for admissions to UK critical care units with severe acute pancreatitis: a secondary analysis of the ICNARC Case Mix Programme Database
    David A Harrison
    Intensive Care National Audit and Research Centre ICNARC, Tavistock House, Tavistock Square, London WC1H 9HR, UK
    Crit Care 11:S1. 2007
    ..We describe the case mix, outcome, and activity of admissions with SAP who were identified from a high-quality clinical database...
  5. doi request reprint Post hoc insights from PAC-Man--the U.K. pulmonary artery catheter trial
    Sheila E Harvey
    Medical Statistics Unit, London School of Hygiene and Tropical Medicine, London, UK
    Crit Care Med 36:1714-21. 2008
    ..K. intensive care units and to generate hypotheses to guide future research by examining subsets of patients included in the PAC-Man Study...
  6. ncbi request reprint Recalibration of risk prediction models in a large multicenter cohort of admissions to adult, general critical care units in the United Kingdom
    David A Harrison
    Intensive Care National Audit and Research Centre, London, UK
    Crit Care Med 34:1378-88. 2006
    ..To assess the performance of published risk prediction models in common use in adult critical care in the United Kingdom and to recalibrate these models in a large representative database of critical care admissions...
  7. doi request reprint The effects of critical care outreach services before and after critical care: a matched-cohort analysis
    David A Harrison
    Intensive Care National Audit and Research Centre, Tavistock House, Tavistock Square, London WC1H 9HR, UK
    J Crit Care 25:196-204. 2010
    ..The purpose of the study was to evaluate the effect of visits from critical care outreach services (CCOS) before admission to and following discharge from critical care...
  8. ncbi request reprint A new measure of acute physiological derangement for patients with exacerbations of obstructive airways disease: the COPD and Asthma Physiology Score
    Martin J Wildman
    Department of Respiratory Medicine, Northern General Hospital, Herries Road, Sheffield S5 7AU, UK
    Respir Med 101:1994-2002. 2007
    ..This depends on the severity of the acute deterioration and the patient's functional reserve. There are currently no validated disease-specific scores that measure the severity of the acute exacerbation...
  9. pmc Case mix, outcomes and comparison of risk prediction models for admissions to adult, general and specialist critical care units for head injury: a secondary analysis of the ICNARC Case Mix Programme Database
    Jonathan A Hyam
    Department of Neurosurgery, Charing Cross Hospital, London, UK
    Crit Care 10:S2. 2006
    ..This report describes the case mix and outcome (mortality, intensive care unit (ICU) and hospital length of stay) for admissions to ICU for head injury and evaluates the predictive ability of five risk adjustment models...
  10. ncbi request reprint A new risk prediction model for critical care: the Intensive Care National Audit & Research Centre (ICNARC) model
    David A Harrison
    Intensive Care National Audit and Research Centre ICNARC, London, UK
    Crit Care Med 35:1091-8. 2007
    ..To develop a new model to improve risk prediction for admissions to adult critical care units in the UK...
  11. pmc The impact of the introduction of critical care outreach services in England: a multicentre interrupted time-series analysis
    Haiyan Gao
    Intensive Care National Audit and Research Centre, Tavistock House, Tavistock Square, London WC1H 9HR, UK
    Crit Care 11:R113. 2007
    ..We undertook a multicentre interrupted time-series analysis of the impact of CCOS, as characterised by the case mix, outcome and activity of admissions to adult, general critical care units in England...
  12. pmc Case mix, outcome and activity for patients admitted to intensive care units requiring chronic renal dialysis: a secondary analysis of the ICNARC Case Mix Programme Database
    Colin A Hutchison
    University Hospital Birmingham NHS Foundation Trust, Queen Elizabeth Medical Centre, Edgbaston, Birmingham, B15 2TH, UK
    Crit Care 11:R50. 2007
    ....
  13. doi request reprint The association between deprivation and hospital mortality for admissions to critical care units in England
    Catherine A Welch
    Intensive Care National Audit and Research Centre, Tavistock House, Tavistock Square, WC1H 9HR, London, UK
    J Crit Care 25:382-90. 2010
    ..It is important to be aware if an association exists because risk prediction models do not adjust for deprivation...
  14. ncbi request reprint Systematic review and evaluation of physiological track and trigger warning systems for identifying at-risk patients on the ward
    Haiyan Gao
    Intensive Care National Audit and Research Centre, Tavistock House, Tavistock Square, London, WC1H 9HR, UK
    Intensive Care Med 33:667-79. 2007
    ....
  15. ncbi request reprint The Pancreatitis Outcome Prediction (POP) Score: a new prognostic index for patients with severe acute pancreatitis
    David A Harrison
    Intensive Care National Audit and Research Centre, Tavistock House, Tavistock Square, London, United Kingdom
    Crit Care Med 35:1703-8. 2007
    ..Some scores cannot be applied until several days into hospital admission. We thus sought to develop a new and more sensitive outcome prediction score--the Pancreatitis Outcome Prediction (POP) Score--for these high-risk patients...
  16. pmc The epidemiology of severe sepsis in England, Wales and Northern Ireland, 1996 to 2004: secondary analysis of a high quality clinical database, the ICNARC Case Mix Programme Database
    David A Harrison
    Intensive Care National Audit and Research Centre ICNARC, Tavistock House, Tavistock Square, London WC1H 9HR, UK
    Crit Care 10:R42. 2006
    ..We interrogated a high quality clinical database to examine trends in the incidence and mortality of severe sepsis over a nine-year period...
  17. pmc Is Drotrecogin alfa (activated) for adults with severe sepsis, cost-effective in routine clinical practice?
    M Zia Sadique
    Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, 15 17 Tavistock Place, London, WC1H 9SH, UK
    Crit Care 15:R228. 2011
    ..There is little evidence on whether DrotAA is cost-effective in routine clinical practice. We assessed whether DrotAA is cost-effective in routine practice for adult patients with severe sepsis and multiple organ systems failing...
  18. pmc Drotrecogin alfa (activated): real-life use and outcomes for the UK
    Kathryn M Rowan
    Intensive Care National Audit and Research Centre, Tavistock House, Tavistock Square, London WC1H 9HR, UK
    Crit Care 12:R58. 2008
    ..1% absolute reduction in 28-day mortality. Drotrecogin alfa (activated; DrotAA) was subsequently approved for use in patients with severe sepsis...
  19. doi request reprint Outcome prediction in critical care: the ICNARC model
    David A Harrison
    Intensive Care National Audit and Research Centre, London, UK
    Curr Opin Crit Care 14:506-12. 2008
    ..To describe the background to, rationale for, and structure and performance of the Intensive Care National Audit & Research Centre risk prediction model...
  20. pmc Identification and characterisation of the high-risk surgical population in the United Kingdom
    Rupert M Pearse
    William Harvey Research Institute, Queen Mary s School of Medicine and Dentistry, London, UK
    Crit Care 10:R81. 2006
    ..The aim of the present study was to estimate the size of the high-risk general surgical population and to describe the outcome and intensive care unit (ICU) resource use...
  21. doi request reprint Effect of specialist retrieval teams on outcomes in children admitted to paediatric intensive care units in England and Wales: a retrospective cohort study
    Padmanabhan Ramnarayan
    Children s Acute Transport Service, Great Ormond Street Hospital, London, UK
    Lancet 376:698-704. 2010
    ..We studied the outcome of children transferred from local hospitals to PICUs...
  22. doi request reprint Prevalence and outcome of cirrhosis patients admitted to UK intensive care: a comparison against dialysis-dependent chronic renal failure patients
    Alastair J O'Brien
    Department of Clinical Pharmacology, University College London, 5 University Street, London WC1E 6JF, UK
    Intensive Care Med 38:991-1000. 2012
    ..Patients with decompensated liver cirrhosis who are admitted to intensive care units (ICU) are perceived, within the UK, as having a particularly poor prognosis...
  23. ncbi request reprint Assessment of the clinical effectiveness of pulmonary artery catheters in management of patients in intensive care (PAC-Man): a randomised controlled trial
    Sheila Harvey
    Intensive Care National Audit and Research Centre, London, UK
    Lancet 366:472-7. 2005
    ..Our aim was, therefore, to ascertain whether hospital mortality is reduced in critically ill patients when they are managed with a PAC...