Research Topics
| A J WrightSummaryAffiliation: Institute for Animal Health Country: UK Publications
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Detail Information
Publications
Erythrocyte folate analysis: a cause for concern?A J Wright
Institute of Food Research, Colney, Norwich, UK
Clin Chem 44:1886-91. 1998..Hence, doubt is cast over the validity of all previous RCF values. Some strategies for accurately assessing RCF are suggested...
Folic acid metabolism in human subjects revisited: potential implications for proposed mandatory folic acid fortification in the UKAnthony J A Wright
Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
Br J Nutr 98:667-75. 2007....
Differential kinetic behavior and distribution for pteroylglutamic acid and reduced folates: a revised hypothesis of the primary site of PteGlu metabolism in humansAnthony J A Wright
Nutrition Department, Institute of Food Research, Norwich NR4 7UA, United Kingdom
J Nutr 135:619-23. 2005....
Comparison of (6 S)-5-methyltetrahydrofolic acid v. folic acid as the reference folate in longer-term human dietary intervention studies assessing the relative bioavailability of natural food folates: comparative changes in folate status following a 16-weAnthony J A Wright
Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
Br J Nutr 103:724-9. 2010..Using (6S)-5-methyltetrahydrofolic acid as the reference folate would avoid future results' validity being questioned...
Erythrocyte folate analysis: saponin added during lysis of whole blood can increase apparent folate concentrations, depending on hemolysate pHA J Wright
Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, United Kingdom
Clin Chem 46:1978-86. 2000..This report challenges this assumption...
Use of an oral/intravenous dual-label stable-isotope protocol to determine folic acid bioavailability from fortified cereal grain foods in womenPaul M Finglas
Nutrition and Consumer Science Division, Institute of Food Research, Norwich, UK
J Nutr 132:936-9. 2002..71 and 0.37, respectively, indicating that some cereal-based vehicles may inhibit absorption of fortificant. However, even the validity of this "relative" approach is questioned...
Is there more to folates than neural-tube defects?Paul M Finglas
Nutrition Department, Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
Proc Nutr Soc 62:591-8. 2003..However, in the future, examination of the concurrent effects of such common gene polymorphisms may be more beneficial...
DNA damage and susceptibility to oxidative damage in lymphocytes: effects of carotenoids in vitro and in vivoSian B Astley
Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
Br J Nutr 91:53-61. 2004..These results suggest that the carotenoids are capable of exerting two overlapping but distinct effects: antioxidant protection by scavenging DNA-damaging free radicals and modulation of DNA repair mechanisms...
Effects of lycopene and lutein supplementation on the expression of functionally associated surface molecules on blood monocytes from healthy male nonsmokersD A Hughes
Diet, Health and Consumer Science Division, Institute of Food Research, Norwich Research Park, Colney, Norwich, Norfolk, NR4 7UA, UK
J Infect Dis 182:S11-5. 2000..These findings emphasize that it cannot be assumed that the effect of one carotenoid will be the same as another, even at the same level of intake...
Comparison of LDL fatty acid and carotenoid concentrations and oxidative resistance of LDL in volunteers from countries with different rates of cardiovascular diseaseAnthony J A Wright
Institute of Food Research, Norwich, Norfolk, UK
Br J Nutr 87:21-9. 2002..In conclusion, LDL composition did not predict resistance to Cu-stimulated oxidation, nor is there evidence that LDL from volunteers in countries with lower rates of CVD have greater resistance to oxidation...
Determination of 5-methyltetrahydrofolate (13C-labeled and unlabeled) in human plasma and urine by combined liquid chromatography mass spectrometryDavid J Hart
Nutrition and Consumer Science Division, Norwich Research Park, Colney, Norwich, NR4 7UA, United Kingdom
Anal Biochem 305:206-13. 2002..2 x 10(-9) and 0.55 x 10(-9) mol/L, respectively. The mean coefficient of variation of the ratios (m/z 463/458) was 7.4%. The method has potential applications for other key folates involved in one-carbon metabolism...
