A J Wright

Summary

Affiliation: Institute for Animal Health
Country: UK

Publications

  1. ncbi request reprint Erythrocyte folate analysis: a cause for concern?
    A J Wright
    Institute of Food Research, Colney, Norwich, UK
    Clin Chem 44:1886-91. 1998
  2. ncbi request reprint Folic acid metabolism in human subjects revisited: potential implications for proposed mandatory folic acid fortification in the UK
    Anthony J A Wright
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
    Br J Nutr 98:667-75. 2007
  3. ncbi request reprint Differential kinetic behavior and distribution for pteroylglutamic acid and reduced folates: a revised hypothesis of the primary site of PteGlu metabolism in humans
    Anthony J A Wright
    Nutrition Department, Institute of Food Research, Norwich NR4 7UA, United Kingdom
    J Nutr 135:619-23. 2005
  4. doi request reprint Comparison of (6 S)-5-methyltetrahydrofolic acid v. folic acid as the reference folate in longer-term human dietary intervention studies assessing the relative bioavailability of natural food folates: comparative changes in folate status following a 16-we
    Anthony J A Wright
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
    Br J Nutr 103:724-9. 2010
  5. ncbi request reprint Erythrocyte folate analysis: saponin added during lysis of whole blood can increase apparent folate concentrations, depending on hemolysate pH
    A J Wright
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, United Kingdom
    Clin Chem 46:1978-86. 2000
  6. ncbi request reprint Use of an oral/intravenous dual-label stable-isotope protocol to determine folic acid bioavailability from fortified cereal grain foods in women
    Paul M Finglas
    Nutrition and Consumer Science Division, Institute of Food Research, Norwich, UK
    J Nutr 132:936-9. 2002
  7. ncbi request reprint Is there more to folates than neural-tube defects?
    Paul M Finglas
    Nutrition Department, Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
    Proc Nutr Soc 62:591-8. 2003
  8. ncbi request reprint DNA damage and susceptibility to oxidative damage in lymphocytes: effects of carotenoids in vitro and in vivo
    Sian B Astley
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
    Br J Nutr 91:53-61. 2004
  9. ncbi request reprint Effects of lycopene and lutein supplementation on the expression of functionally associated surface molecules on blood monocytes from healthy male nonsmokers
    D A Hughes
    Diet, Health and Consumer Science Division, Institute of Food Research, Norwich Research Park, Colney, Norwich, Norfolk, NR4 7UA, UK
    J Infect Dis 182:S11-5. 2000
  10. ncbi request reprint Comparison of LDL fatty acid and carotenoid concentrations and oxidative resistance of LDL in volunteers from countries with different rates of cardiovascular disease
    Anthony J A Wright
    Institute of Food Research, Norwich, Norfolk, UK
    Br J Nutr 87:21-9. 2002

Detail Information

Publications11

  1. ncbi request reprint Erythrocyte folate analysis: a cause for concern?
    A J Wright
    Institute of Food Research, Colney, Norwich, UK
    Clin Chem 44:1886-91. 1998
    ..Hence, doubt is cast over the validity of all previous RCF values. Some strategies for accurately assessing RCF are suggested...
  2. ncbi request reprint Folic acid metabolism in human subjects revisited: potential implications for proposed mandatory folic acid fortification in the UK
    Anthony J A Wright
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
    Br J Nutr 98:667-75. 2007
    ....
  3. ncbi request reprint Differential kinetic behavior and distribution for pteroylglutamic acid and reduced folates: a revised hypothesis of the primary site of PteGlu metabolism in humans
    Anthony J A Wright
    Nutrition Department, Institute of Food Research, Norwich NR4 7UA, United Kingdom
    J Nutr 135:619-23. 2005
    ..Because of the observed differential plasma response and the hypothesized difference in the site of initial metabolism, the historical use of PteGlu as a "reference folate" in studies of folate bioavailability is seriously questioned...
  4. doi request reprint Comparison of (6 S)-5-methyltetrahydrofolic acid v. folic acid as the reference folate in longer-term human dietary intervention studies assessing the relative bioavailability of natural food folates: comparative changes in folate status following a 16-we
    Anthony J A Wright
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
    Br J Nutr 103:724-9. 2010
    ..Using (6S)-5-methyltetrahydrofolic acid as the reference folate would avoid future results' validity being questioned...
  5. ncbi request reprint Erythrocyte folate analysis: saponin added during lysis of whole blood can increase apparent folate concentrations, depending on hemolysate pH
    A J Wright
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, United Kingdom
    Clin Chem 46:1978-86. 2000
    ..This report challenges this assumption...
  6. ncbi request reprint Use of an oral/intravenous dual-label stable-isotope protocol to determine folic acid bioavailability from fortified cereal grain foods in women
    Paul M Finglas
    Nutrition and Consumer Science Division, Institute of Food Research, Norwich, UK
    J Nutr 132:936-9. 2002
    ..71 and 0.37, respectively, indicating that some cereal-based vehicles may inhibit absorption of fortificant. However, even the validity of this "relative" approach is questioned...
  7. ncbi request reprint Is there more to folates than neural-tube defects?
    Paul M Finglas
    Nutrition Department, Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
    Proc Nutr Soc 62:591-8. 2003
    ..However, in the future, examination of the concurrent effects of such common gene polymorphisms may be more beneficial...
  8. ncbi request reprint DNA damage and susceptibility to oxidative damage in lymphocytes: effects of carotenoids in vitro and in vivo
    Sian B Astley
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
    Br J Nutr 91:53-61. 2004
    ..These results suggest that the carotenoids are capable of exerting two overlapping but distinct effects: antioxidant protection by scavenging DNA-damaging free radicals and modulation of DNA repair mechanisms...
  9. ncbi request reprint Effects of lycopene and lutein supplementation on the expression of functionally associated surface molecules on blood monocytes from healthy male nonsmokers
    D A Hughes
    Diet, Health and Consumer Science Division, Institute of Food Research, Norwich Research Park, Colney, Norwich, Norfolk, NR4 7UA, UK
    J Infect Dis 182:S11-5. 2000
    ..These findings emphasize that it cannot be assumed that the effect of one carotenoid will be the same as another, even at the same level of intake...
  10. ncbi request reprint Comparison of LDL fatty acid and carotenoid concentrations and oxidative resistance of LDL in volunteers from countries with different rates of cardiovascular disease
    Anthony J A Wright
    Institute of Food Research, Norwich, Norfolk, UK
    Br J Nutr 87:21-9. 2002
    ..In conclusion, LDL composition did not predict resistance to Cu-stimulated oxidation, nor is there evidence that LDL from volunteers in countries with lower rates of CVD have greater resistance to oxidation...
  11. ncbi request reprint Determination of 5-methyltetrahydrofolate (13C-labeled and unlabeled) in human plasma and urine by combined liquid chromatography mass spectrometry
    David J Hart
    Nutrition and Consumer Science Division, Norwich Research Park, Colney, Norwich, NR4 7UA, United Kingdom
    Anal Biochem 305:206-13. 2002
    ..2 x 10(-9) and 0.55 x 10(-9) mol/L, respectively. The mean coefficient of variation of the ratios (m/z 463/458) was 7.4%. The method has potential applications for other key folates involved in one-carbon metabolism...