Jinliang Wang

..Simulations also show that the confidence intervals estimated by bootstrapping are appropriate for different estimators provided that the number of loci used in the estimation is not small...

..The statistical properties of the four measurements and their relationships are investigated analytically and are examined by applying these methods to simulated and empirical data...

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..It is concluded that the markers, except when they are highly informative to yield accurate paternity assignments or exclusions, should be split into two subsets which are used separately in the paternity and downstream analyses...

..I suggest continuing the use of G(ST), with caution in its interpretation when highly polymorphic markers are used, before a better estimator of F(ST) that explicitly accounts for mutations is developed...

..The new method can handle a large sample with thousands of individuals and the number of markers limited only by the computer memory...

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..It also gives reasonably accurate estimates of other admixture parameters. A human mtDNA sequence data set was analyzed to demonstrate the method, and the analysis results are discussed and compared with those from previous studies...

..This model will facilitate the population genetic analysis of a wide range of organisms on the basis of next-generation sequence data...

..In addition, they can be used to guide experimental designs of parentage analyses in selecting markers and determining the number of offspring to be sampled and genotyped...

..These applications are demonstrated by numerical examples using both hypothetical and empirical data sets and discussed in the context of practical parentage exclusion analyses...

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..With some modification, it could be applied to monoecious diploid populations with self-fertilization, and to populations with overlapping generations...

..Data from wild populations of baboons and hihi (stitchbird) were analyzed by EPA to demonstrate the use of the estimator in practical sampling and genotyping situations...

..It is tested extensively on simulated data with a varying number of marker loci, different rates of typing errors, and various sample sizes and family structures and applied to two empirical data sets to demonstrate its usefulness...

..Both simulated and empirical data were analysed by the new and previous methods to compare their statistical properties and accuracies...

..The low correlation between MLH and fitness traits, which is widely observed in numerous empirical studies, might be partially caused by the adoption of this inefficient estimator of genomic inbreeding...

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..For less prolific species, the approach is still effective if the mating ratio is large so that a high marker-assisted selection pressure on the rarer sex can be maintained...

..In an application of the pseudo-likelihood method to a large data set of an olive fly population, more precise estimates of Ne are obtained than those from the F-statistic method...

..Compared to previous estimators, the new one is generally advantageous, especially for highly polymorphic loci and/or small sample sizes...

..Bootstrapping and permutations are used to obtain the 95% confidence intervals of each relatedness or inbreeding estimate, and to test the difference in averages between groups...

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..The method is applied to a human data set and a wolflike canids data set, and the results obtained are discussed in comparison with those from other estimators and from previous studies...

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..Thus considerations of dominance coefficients of mutations lend further support to our previous conclusion that mutation-selection balance is a plausible mechanism of the maintenance of the genetic variance in natural populations...

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..This work highlights the effects of inbreeding at early life-history stages and the repercussions for the long-term population viability of threatened species...

..We also developed an alternative regression model to Ballou's, which showed an improvement in the detection of purging of mildly deleterious alleles but performed less well if deleterious alleles were of a large effect...

..The study re-emphasises the necessity to avoid inbreeding in captive breeding programmes and shows that purging cannot be relied upon to remove deleterious alleles from zoo populations...

..The low rate of paternity assignments indicated that males living outside the study area contributed substantially to the reproduction of the cheetah population...

..In addition, bumble bee-mediated gene flow in plants is likely to occur over large distances and plant-bumble bee conservation requires landscape-scale action...

..The simulations results are in general compatible with empirical observations...

..This research provides a rare investigation into inbreeding in a cooperative mammal, revealing high levels of inbreeding, considerable negative consequences and complex interactions with the social environment...

..The simulation results and their implications are discussed in the context of biological conservation and tests for purging...

..Interspecific recombination may increase mtDNA variability within species and can have implications for phylogenetic studies...

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..The assumptions made in developing the theory and methods and the applications of MAS in conservation are discussed...

..This article suggests that dominance is the main cause for increased genetic variances for fitness components and fitness-related traits after bottlenecks observed in various experiments...