N J Walton

Summary

Affiliation: Institute for Animal Health
Country: UK

Publications

  1. ncbi request reprint Novel approaches to the biosynthesis of vanillin
    N J Walton
    Food Safety Science Division, Institute of Food Research, Norwich Research Park, Colney, NR4 7UA, Norwich, UK
    Curr Opin Biotechnol 11:490-6. 2000
  2. ncbi request reprint Vanillin
    Nicholas J Walton
    Food Safety Science Division, Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
    Phytochemistry 63:505-15. 2003
  3. pmc Rerouting the plant phenylpropanoid pathway by expression of a novel bacterial enoyl-CoA hydratase/lyase enzyme function
    M J Mayer
    Division of Food Safety Science, Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, United Kingdom
    Plant Cell 13:1669-82. 2001
  4. ncbi request reprint Metabolism of ferulic acid to vanillin. A bacterial gene of the enoyl-SCoA hydratase/isomerase superfamily encodes an enzyme for the hydration and cleavage of a hydroxycinnamic acid SCoA thioester
    M J Gasson
    Department of Genetics, Institute of Food Research, Norwich Laboratory, Norwich Research Park, Colney, Norwich NR4 7UA, United Kingdom
    J Biol Chem 273:4163-70. 1998
  5. ncbi request reprint 4-Hydroxycinnamoyl-CoA hydratase/lyase, an enzyme of phenylpropanoid cleavage from Pseudomonas, causes formation of C(6)-C(1) acid and alcohol glucose conjugates when expressed in hairy roots of Datura stramonium L
    Adinpunya Mitra
    Food Safety Science Division, Institute of Food Research, Norwich Resesrch Park, Colney, Norwich NR4 7UA, UK
    Planta 215:79-89. 2002
  6. ncbi request reprint The 1.8 A resolution structure of hydroxycinnamoyl-coenzyme A hydratase-lyase (HCHL) from Pseudomonas fluorescens, an enzyme that catalyses the transformation of feruloyl-coenzyme A to vanillin
    Philip M Leonard
    Structural Biology Laboratory, Department of Chemistry, University of York, Heslington, York YO10 5YW, England
    Acta Crystallogr D Biol Crystallogr 62:1494-501. 2006
  7. doi request reprint A ternary complex of hydroxycinnamoyl-CoA hydratase-lyase (HCHL) with acetyl-CoA and vanillin gives insights into substrate specificity and mechanism
    Joseph P Bennett
    York Structural Biology Laboratory, Department of Chemistry, University of York, Heslington, York YO10 5YW, UK
    Biochem J 414:281-9. 2008

Collaborators

  • A Narbad
  • Melinda J Mayer
  • Ian J S Fairlamb
  • G Williamson
  • Fred A Mellon
  • Joseph P Bennett
  • Gideon Grogan
  • A Marek Brzozowski
  • Philip M Leonard
  • Adinpunya Mitra
  • Lucille Bertin
  • Benjamin Moulton
  • M J Gasson
  • Caroline M Marshall
  • Derek J Smith
  • Chandra S Verma
  • Andrey Lebedev
  • Keith W Waldron
  • Adrian J Parr
  • Anthony J Michael
  • W R McLauchlan
  • A J Parr
  • M J Rhodes
  • E L Parsons
  • J Payne
  • Y Kitamura

Detail Information

Publications7

  1. ncbi request reprint Novel approaches to the biosynthesis of vanillin
    N J Walton
    Food Safety Science Division, Institute of Food Research, Norwich Research Park, Colney, NR4 7UA, Norwich, UK
    Curr Opin Biotechnol 11:490-6. 2000
    ..Attempts to introduce vanillin production into other organisms by genetic engineering have begun...
  2. ncbi request reprint Vanillin
    Nicholas J Walton
    Food Safety Science Division, Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
    Phytochemistry 63:505-15. 2003
    ..Finally, the significance of the latest biosynthetic and biotechnological developments is reviewed briefly in relation to authentication of vanillin...
  3. pmc Rerouting the plant phenylpropanoid pathway by expression of a novel bacterial enoyl-CoA hydratase/lyase enzyme function
    M J Mayer
    Division of Food Safety Science, Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, United Kingdom
    Plant Cell 13:1669-82. 2001
    ....
  4. ncbi request reprint Metabolism of ferulic acid to vanillin. A bacterial gene of the enoyl-SCoA hydratase/isomerase superfamily encodes an enzyme for the hydration and cleavage of a hydroxycinnamic acid SCoA thioester
    M J Gasson
    Department of Genetics, Institute of Food Research, Norwich Laboratory, Norwich Research Park, Colney, Norwich NR4 7UA, United Kingdom
    J Biol Chem 273:4163-70. 1998
    ..The gene product is a member of the enoyl-SCoA hydratase/isomerase superfamily...
  5. ncbi request reprint 4-Hydroxycinnamoyl-CoA hydratase/lyase, an enzyme of phenylpropanoid cleavage from Pseudomonas, causes formation of C(6)-C(1) acid and alcohol glucose conjugates when expressed in hairy roots of Datura stramonium L
    Adinpunya Mitra
    Food Safety Science Division, Institute of Food Research, Norwich Resesrch Park, Colney, Norwich NR4 7UA, UK
    Planta 215:79-89. 2002
    ..The findings are discussed in the context of a diversion of phenylpropanoid metabolism, and the ability of plants and plant cultures to conjugate phenolic compounds...
  6. ncbi request reprint The 1.8 A resolution structure of hydroxycinnamoyl-coenzyme A hydratase-lyase (HCHL) from Pseudomonas fluorescens, an enzyme that catalyses the transformation of feruloyl-coenzyme A to vanillin
    Philip M Leonard
    Structural Biology Laboratory, Department of Chemistry, University of York, Heslington, York YO10 5YW, England
    Acta Crystallogr D Biol Crystallogr 62:1494-501. 2006
    ....
  7. doi request reprint A ternary complex of hydroxycinnamoyl-CoA hydratase-lyase (HCHL) with acetyl-CoA and vanillin gives insights into substrate specificity and mechanism
    Joseph P Bennett
    York Structural Biology Laboratory, Department of Chemistry, University of York, Heslington, York YO10 5YW, UK
    Biochem J 414:281-9. 2008
    ....