D M Taylor

Summary

Affiliation: Institute for Animal Health
Country: UK

Publications

  1. ncbi request reprint The effect of dry heat on the ME7 strain of mouse-passaged scrapie agent
    D M Taylor
    BBSRC and MRC Neuropathogenesis Unit, Institute for Animal Health, Edinburgh, UK
    J Gen Virol 77:3161-4. 1996
  2. ncbi request reprint Observations on thermostable subpopulations of the unconventional agents that cause transmissible degenerative encephalopathies
    D M Taylor
    Neuropathogenesis Unit, Institute for Animal Health, Edinburgh, UK
    Vet Microbiol 64:33-8. 1998
  3. ncbi request reprint Bovine spongiform encephalopathy and human health
    D M Taylor
    Institute for Animal Health, AFRC and MRC Neuropathogenesis Unit, Edinburgh
    Vet Rec 125:413-5. 1989
  4. ncbi request reprint Survival of scrapie agent after exposure to sodium dodecyl sulphate and heat
    D M Taylor
    Neuropathogenesis Unit, Institute for Animal Health, Edinburgh, UK
    Vet Microbiol 67:13-6. 1999
  5. ncbi request reprint Exposure to autoclaving or sodium hydroxide extends the dose-response curve of the 263K strain of scrapie agent in hamsters
    D M Taylor
    BBSRC and MRC Neuropathogenesis Unit, Institute for Animal Health, Edinburgh, UK
    J Gen Virol 77:811-3. 1996
  6. ncbi request reprint Inactivation of transmissible degenerative encephalopathy agents: A review
    D M Taylor
    Neuropathogenesis Unit, Institute for Animal Health, West Mains Road, Edinburgh, EH9 3JF, UK
    Vet J 159:10-7. 2000
  7. ncbi request reprint Inactivation of the unconventional agents of scrapie, bovine spongiform encephalopathy and Creutzfeldt-Jakob disease
    D M Taylor
    AFRC and MRC Neuropathogenesis Unit, Institute for Animal Health, Edinburgh
    J Hosp Infect 18:141-6. 1991
  8. ncbi request reprint Closely similar values obtained when the ME7 strain of scrapie agent was titrated in parallel by two individuals in separate laboratories using two sublines of C57BL mice
    D M Taylor
    Neuropathogenesis Unit, Institute for Animal Health, West Mains Road, Edinburgh, UK
    J Virol Methods 86:35-40. 2000

Detail Information

Publications8

  1. ncbi request reprint The effect of dry heat on the ME7 strain of mouse-passaged scrapie agent
    D M Taylor
    BBSRC and MRC Neuropathogenesis Unit, Institute for Animal Health, Edinburgh, UK
    J Gen Virol 77:3161-4. 1996
    ..No infectivity was recovered after a 1 h exposure at 200 degrees C. These data suggest that scrapie-like agents are unlikely to survive incineration...
  2. ncbi request reprint Observations on thermostable subpopulations of the unconventional agents that cause transmissible degenerative encephalopathies
    D M Taylor
    Neuropathogenesis Unit, Institute for Animal Health, Edinburgh, UK
    Vet Microbiol 64:33-8. 1998
    ..These observations suggest that inactivation procedures that do not involve rapid and effective fixation of PrP(Sc) may be better candidates for dealing effectively with scrapie-like agents...
  3. ncbi request reprint Bovine spongiform encephalopathy and human health
    D M Taylor
    Institute for Animal Health, AFRC and MRC Neuropathogenesis Unit, Edinburgh
    Vet Rec 125:413-5. 1989
    ..Epidemiological and experimental evidence is examined which suggests that this is unlikely...
  4. ncbi request reprint Survival of scrapie agent after exposure to sodium dodecyl sulphate and heat
    D M Taylor
    Neuropathogenesis Unit, Institute for Animal Health, Edinburgh, UK
    Vet Microbiol 67:13-6. 1999
    ..Although the infectivity titre of the sample that was autoclaved in SDS was reduced considerably, infectivity was present in all of the samples exposed to cold or hot SDS...
  5. ncbi request reprint Exposure to autoclaving or sodium hydroxide extends the dose-response curve of the 263K strain of scrapie agent in hamsters
    D M Taylor
    BBSRC and MRC Neuropathogenesis Unit, Institute for Animal Health, Edinburgh, UK
    J Gen Virol 77:811-3. 1996
    ..These results confirmed that, after chemical or physical treatment, infectivity titre should not be calculated by comparing the incubation period from a single dilution-group against a standard dose-response curve for untreated agent...
  6. ncbi request reprint Inactivation of transmissible degenerative encephalopathy agents: A review
    D M Taylor
    Neuropathogenesis Unit, Institute for Animal Health, West Mains Road, Edinburgh, EH9 3JF, UK
    Vet J 159:10-7. 2000
    ..The infectivity levels in histologically-fixed tissue can be reduced substantially by treatment with concentrated formic acid without adversely affecting the microscopic quality of the tissue...
  7. ncbi request reprint Inactivation of the unconventional agents of scrapie, bovine spongiform encephalopathy and Creutzfeldt-Jakob disease
    D M Taylor
    AFRC and MRC Neuropathogenesis Unit, Institute for Animal Health, Edinburgh
    J Hosp Infect 18:141-6. 1991
    ..As the model for the group, scrapie agent has been used in experiments to devise general standards for decontamination of the agents of the TDE...
  8. ncbi request reprint Closely similar values obtained when the ME7 strain of scrapie agent was titrated in parallel by two individuals in separate laboratories using two sublines of C57BL mice
    D M Taylor
    Neuropathogenesis Unit, Institute for Animal Health, West Mains Road, Edinburgh, UK
    J Virol Methods 86:35-40. 2000
    ..The data confirm the validity of comparing these types of transmission data generated in different laboratories when a common methodology is used...