Affiliation: Institute of Cancer Research
- Dosimetric explanations of fatigue in head and neck radiotherapy: an analysis from the PARSPORT Phase III trialSarah L Gulliford
Institute of Cancer Research, UK
Radiother Oncol 104:205-12. 2012..One possible explanation was the difference in dose to central nervous system (CNS) structures due to differing beam portals. Using data from the trial, a dosimetric analysis of individual CNS structures was performed...
- Generating compensation designs for tangential breast irradiation with artificial neural networksS Gulliford
Joint Department of Physics, Institute of Cancer Research and Royal Marsden Hospital NHS Trust, Sutton, Surrey, UK
Phys Med Biol 47:277-88. 2002..The results of this study demonstrate the ability of an ANN to learn the general shape of compensation required and explore the use of image-based ANNs in the design of intensity-modulated fields...
- A comparison of dose-volume constraints derived using peak and longitudinal definitions of late rectal toxicitySarah L Gulliford
Joint Department of Physics, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, UK
Radiother Oncol 94:241-7. 2010..An alternative definition (integrated longitudinal toxicity (ILT)) is proposed which takes into account both the severity and the duration of the complication...
- Reduction of small and large bowel irradiation using an optimized intensity-modulated pelvic radiotherapy technique in patients with prostate cancerC M Nutting
Academic Department of Radiotherapy, Institute of Cancer Research and the Royal Marsden NHS Trust, Sutton, Surrey, UK
Int J Radiat Oncol Biol Phys 48:649-56. 2000..To investigate the role of intensity-modulated radiation therapy (IMRT) to irradiate the prostate gland and pelvic lymph nodes while sparing critical pelvic organs, and to optimize the number of beams required...
- Improvements in target coverage and reduced spinal cord irradiation using intensity-modulated radiotherapy (IMRT) in patients with carcinoma of the thyroid glandC M Nutting
Academic Department of Radiotherapy, Institute of Cancer Research, Surrey, SM2 5PT, Sutton, UK
Radiother Oncol 60:173-80. 2001..A simultaneous integrated boost technique with five equispaced fields produced the best dose distribution. IMRT should reduce the risk of myelopathy or may allow dose escalation in patients with thyroid cancer...