C A L Oura

Summary

Affiliation: Institute for Animal Health
Country: UK

Publications

  1. doi request reprint African horse sickness in The Gambia: circulation of a live-attenuated vaccine-derived strain
    C A L Oura
    Institute for Animal Health, Pirbright, Woking, Surrey, UK
    Epidemiol Infect 140:462-5. 2012
  2. doi request reprint Colostral antibody protection and interference with immunity in lambs born from sheep vaccinated with an inactivated Bluetongue serotype 8 vaccine
    C A L Oura
    Institute for Animal Health, Pirbright Laboratory, Ash Road, Woking, Surrey GU240NF, UK
    Vaccine 28:2749-53. 2010
  3. doi request reprint Theileria parva genetic diversity and haemoparasite prevalence in cattle and wildlife in and around Lake Mburo National Park in Uganda
    Chris A L Oura
    Department of Microbiology and Parasitology, Faculty of Vet Medicine, University of Makerere, P O Box 7062, Kampala, Uganda
    Parasitol Res 108:1365-74. 2011
  4. ncbi request reprint Theileria parva live vaccination: parasite transmission, persistence and heterologous challenge in the field
    C A L Oura
    Institute for Animal Health, Pirbright Laboratory, Ash Road, Woking GU24ONF, Surrey
    Parasitology 134:1205-13. 2007
  5. doi request reprint Haemoparasite prevalence and Theileria parva strain diversity in Cape buffalo (Syncerus caffer) in Uganda
    C A L Oura
    Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, University of Makerere, P O Box 7062, Kampala, Uganda
    Vet Parasitol 175:212-9. 2011
  6. ncbi request reprint In vivo depletion of CD8+ T lymphocytes abrogates protective immunity to African swine fever virus
    C A L Oura
    Institute for Animal Health, Ash Road, Pirbright, Woking, Surrey GU24 0NF, UK
    J Gen Virol 86:2445-50. 2005
  7. ncbi request reprint Population genetic analysis and sub-structuring of Theileria parva in Uganda
    C A L Oura
    Department of Microbiology and Parasitology, Faculty of Vet Medecine, University of Makerere, P O Box 7062, Kampala, Uganda
    Mol Biochem Parasitol 140:229-39. 2005
  8. doi request reprint Seroconversion, neutralising antibodies and protection in bluetongue serotype 8 vaccinated sheep
    C A L Oura
    Institute for Animal Health, Pirbright Laboratory, Ash Road, Pirbright, Woking, Surrey GU240NF, UK
    Vaccine 27:7326-30. 2009
  9. ncbi request reprint The persistence of component Theileria parva stocks in cattle immunized with the 'Muguga cocktail' live vaccine against East Coast fever in Uganda
    C A L Oura
    Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, Makerere University, P O Box 7062, Kampala, Uganda
    Parasitology 129:27-42. 2004
  10. ncbi request reprint Clinical signs and pathology shown by British sheep and cattle infected with bluetongue virus serotype 8 derived from the 2006 outbreak in northern Europe
    K E Darpel
    Institute for Animal Health, Ash Road, Pirbright, Woking, Surrey
    Vet Rec 161:253-61. 2007

Collaborators

Detail Information

Publications27

  1. doi request reprint African horse sickness in The Gambia: circulation of a live-attenuated vaccine-derived strain
    C A L Oura
    Institute for Animal Health, Pirbright, Woking, Surrey, UK
    Epidemiol Infect 140:462-5. 2012
    ....
  2. doi request reprint Colostral antibody protection and interference with immunity in lambs born from sheep vaccinated with an inactivated Bluetongue serotype 8 vaccine
    C A L Oura
    Institute for Animal Health, Pirbright Laboratory, Ash Road, Woking, Surrey GU240NF, UK
    Vaccine 28:2749-53. 2010
    ..These results suggest that colostral antibodies may interfere with vaccination in lambs up to at least 14 weeks of age...
  3. doi request reprint Theileria parva genetic diversity and haemoparasite prevalence in cattle and wildlife in and around Lake Mburo National Park in Uganda
    Chris A L Oura
    Department of Microbiology and Parasitology, Faculty of Vet Medicine, University of Makerere, P O Box 7062, Kampala, Uganda
    Parasitol Res 108:1365-74. 2011
    ..parva genotypes to the cattle population...
  4. ncbi request reprint Theileria parva live vaccination: parasite transmission, persistence and heterologous challenge in the field
    C A L Oura
    Institute for Animal Health, Pirbright Laboratory, Ash Road, Woking GU24ONF, Surrey
    Parasitology 134:1205-13. 2007
    ....
  5. doi request reprint Haemoparasite prevalence and Theileria parva strain diversity in Cape buffalo (Syncerus caffer) in Uganda
    C A L Oura
    Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, University of Makerere, P O Box 7062, Kampala, Uganda
    Vet Parasitol 175:212-9. 2011
    ....
  6. ncbi request reprint In vivo depletion of CD8+ T lymphocytes abrogates protective immunity to African swine fever virus
    C A L Oura
    Institute for Animal Health, Ash Road, Pirbright, Woking, Surrey GU24 0NF, UK
    J Gen Virol 86:2445-50. 2005
    ..These experiments indicate an important role for CD8+ lymphocytes, particularly CD8beta+ lymphocytes, in ASF protective immunity...
  7. ncbi request reprint Population genetic analysis and sub-structuring of Theileria parva in Uganda
    C A L Oura
    Department of Microbiology and Parasitology, Faculty of Vet Medecine, University of Makerere, P O Box 7062, Kampala, Uganda
    Mol Biochem Parasitol 140:229-39. 2005
    ..The population from Kayunga was in linkage disequilibrium. Genetic distances and Wrights fixation index (F(ST)) indicate that there is evidence for geographical sub-structuring between the Lira and the Kayunga populations...
  8. doi request reprint Seroconversion, neutralising antibodies and protection in bluetongue serotype 8 vaccinated sheep
    C A L Oura
    Institute for Animal Health, Pirbright Laboratory, Ash Road, Pirbright, Woking, Surrey GU240NF, UK
    Vaccine 27:7326-30. 2009
    ..The sandwich (double antigen) ELISA assays were found to be more sensitive at detecting antibodies in vaccinated sheep than the competitive ELISAs...
  9. ncbi request reprint The persistence of component Theileria parva stocks in cattle immunized with the 'Muguga cocktail' live vaccine against East Coast fever in Uganda
    C A L Oura
    Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, Makerere University, P O Box 7062, Kampala, Uganda
    Parasitology 129:27-42. 2004
    ..parva genotypes showing there was a significant level of tick challenge. Some of the vaccinated animals become infected with a subset of local genotypes providing evidence for limited vaccine 'breakthrough'...
  10. ncbi request reprint Clinical signs and pathology shown by British sheep and cattle infected with bluetongue virus serotype 8 derived from the 2006 outbreak in northern Europe
    K E Darpel
    Institute for Animal Health, Ash Road, Pirbright, Woking, Surrey
    Vet Rec 161:253-61. 2007
    ..Postmortem examinations revealed pathology in the cattle that was more severe than suggested by the mild clinical signs, but the pathological and clinical findings in the sheep were more consistent...
  11. doi request reprint Bluetongue virus: European Community proficiency test (2007) to evaluate ELISA and RT-PCR detection methods with special reference to pooling of samples
    C A Batten
    Institute for Animal Health, Ash Road, Pirbright, Woking GU24 ONF, UK
    Vet Microbiol 135:380-3. 2009
    ..Diluting samples taken at the peak of viraemia at 1/10 however resulted in no loss in sensitivity...
  12. ncbi request reprint Application of a reverse line blot assay to the study of haemoparasites in cattle in Uganda
    C A L Oura
    Department of Microbiology and Parasitology, Faculty of Vet Medicine, Makerere University, Kampala, Uganda
    Int J Parasitol 34:603-13. 2004
    ..mutans and possibly T. taurotragi and T. velifera, may also cause clinical disease. Overall, the results presented here highlight the complexity of tick-borne pathogen infections in cattle in Uganda...
  13. ncbi request reprint Bluetongue virus: European Community inter-laboratory comparison tests to evaluate ELISA and RT-PCR detection methods
    C A Batten
    Institute for Animal Health, Ash Road, Pirbright, Woking GU24 ONF, UK
    Vet Microbiol 129:80-8. 2008
    ..These two ring trails provide evidence that national reference laboratories within the EC are capable of detecting BTV antibodies and RNA and provide specificity and sensitivity information on the detection methods currently available...
  14. ncbi request reprint Equine encephalosis virus: evidence for circulation beyond southern Africa
    C A L Oura
    Institute for Animal Health, Pirbright, Woking, Surrey, UK
    Epidemiol Infect 140:1982-6. 2012
    ..This evidence for EEV circulation in countries in East and West Africa sheds light on how the virus may have reached Israel to cause the recent outbreak in 2009...
  15. doi request reprint Bluetongue virus serotype 26: infection kinetics and pathogenesis in Dorset Poll sheep
    C A Batten
    Institute for Animal Health, Ash Road, Pirbright, Woking, Surrey GU24 0NF, UK
    Vet Microbiol 157:119-24. 2012
    ..Four of the five remaining sheep developed neutralising antibodies to BTV-26, measured by a serum neutralisation test (SNT), with titres (log(10)) ranging from 1.40 to 2.08...
  16. doi request reprint Haemoparasite infection kinetics and the population structure of Theileria parva on a single farm in Uganda
    B B Asiimwe
    Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, University of Makerere, P O Box 7062, Kampala, Uganda
    Vet Parasitol 193:8-14. 2013
    ..parva population was found to be in linkage disequilibrium. The basis for this high diversity coupled with apparent sub-structuring is discussed in relation to the possible causes...
  17. doi request reprint Infection kinetics of Epizootic Haemorrhagic Disease virus serotype 6 in Holstein-Friesian cattle
    C A Batten
    Institute for Animal Health, Ash Road, Pirbright, Woking, Surrey GU24 0NF, UK
    Vet Microbiol 154:23-8. 2011
    ..20 to 2.38 at the end of the study. Virus was isolated from the blood of infected animals from as early as 2dpi up to 28dpi...
  18. ncbi request reprint A panel of microsatellite and minisatellite markers for the characterisation of field isolates of Theileria parva
    C A L Oura
    Department of Microbiology and Parasitology, Veterinary Faculty, University of Makerere, P O Box 7062, Kampala, Uganda
    Int J Parasitol 33:1641-53. 2003
    ..parva. Cluster analysis of multilocus genotypes from the 14 isolates (using a neighbour joining algorithm) revealed that genetic similarity between isolates was not obviously related to their geographical origin...
  19. doi request reprint Evaluation of the humoral immune response in adult dairy cattle three years after vaccination with a bluetongue serotype 8 inactivated vaccine
    C A L Oura
    Institute for Animal Health, Pirbright Laboratory, Ash Road, Woking, Surrey GU240NF, UK
    Vaccine 30:112-5. 2012
    ..This extended duration of protection may have contributed towards the rapid and efficient eradication of BTV-8 from many European countries, despite reducing levels of vaccine coverage...
  20. doi request reprint Experimental infection of camels with bluetongue virus
    C A Batten
    Institute for Animal Health, Ash Road, Pirbright, Woking, GU24 0NF, UK
    Res Vet Sci 90:533-5. 2011
    ..Virus was isolated from the blood of all three animals suggesting that camels may act as a reservoir for BTV and play an important role in its transmission...
  21. doi request reprint Bluetongue virus serotype 26: Infection kinetics, pathogenesis and possible contact transmission in goats
    C A Batten
    Institute for Animal Health, Ash Road, Pirbright, Woking, Surrey GU24 0NF, UK Electronic address
    Vet Microbiol 162:62-7. 2013
    ..Preliminary evidence also indicates that BTV-26 may be spread by contact transmission between goats, however a more detailed study is required in order to confirm this observation...
  22. ncbi request reprint Development and initial evaluation of a real-time RT-PCR assay to detect bluetongue virus genome segment 1
    A E Shaw
    Pirbright Laboratory, Institute for Animal Health, Pirbright, Surrey GU24 0NF, United Kingdom
    J Virol Methods 145:115-26. 2007
    ..These studies have demonstrated the value of the assay for the rapid screening of field samples...
  23. doi request reprint Review: lumpy skin disease: an emerging threat to Europe, the Middle East and Asia
    E S M Tuppurainen
    Institute for Animal Health, Pirbright, Surrey, UK
    Transbound Emerg Dis 59:40-8. 2012
    ..We also review the latest findings on the epidemiology of LSD, its mechanisms of transmission, the potential role of wildlife in its maintenance and spread and the diagnostic tests and control methods currently available...
  24. doi request reprint Peste des petits ruminants: a suitable candidate for eradication?
    M D Baron
    Institute for Animal Health, Ash Road, Pirbright, Surrey GU24 0NF
    Vet Rec 169:16-21. 2011
    ....
  25. doi request reprint Midge-transmitted bluetongue in domestic dogs
    C A L Oura
    Institute for Animal Health, Pirbright, Woking, UK
    Epidemiol Infect 139:1396-400. 2011
    ..This finding increases the chances of dogs being infected with BTV during an outbreak but their role in the onward transmission of BTV remains unproven...
  26. pmc Evaluation of the humoral immune responses in adult cattle and sheep, 4 and 2.5 years post-vaccination with a bluetongue serotype 8 inactivated vaccine
    C A Batten
    The Pirbright Institute, Ash Road, Woking, Surrey, GU24 0NF, UK Electronic address
    Vaccine 31:3783-5. 2013
    ..5 years in sheep that had been vaccinated on two occasions one year apart. These results have implications for future bluetongue surveillance programmes and vaccine control strategies. ..
  27. ncbi request reprint Linkage disequilibrium between alleles at highly polymorphic mini- and micro-satellite loci of Theileria parva isolated from cattle in three regions of Kenya
    D O Odongo
    International Livestock Research Institute, P O Box 30709, Nairobi 00100, Kenya
    Int J Parasitol 36:937-46. 2006
    ..parva populations. A novel observation was that disequilibrium was also detected between alleles at three individual pairs of VNTR loci when isolates from the three regional meta-populations were pooled for analysis...