Anne E Osbourn

Summary

Affiliation: Institute for Animal Health
Country: UK

Publications

  1. doi request reprint The saponins: polar isoprenoids with important and diverse biological activities
    Anne Osbourn
    Department of Metabolic Biology, John Innes Centre, Norwich Research Park, UK
    Nat Prod Rep 28:1261-8. 2011
  2. doi request reprint Secondary metabolic gene clusters: evolutionary toolkits for chemical innovation
    Anne Osbourn
    Department of Metabolic Biology, John Innes Centre, Norwich NR4 7UH, UK
    Trends Genet 26:449-57. 2010
  3. pmc Operons
    Anne E Osbourn
    Department of Metabolic Biology, John Innes Centre, Colney Lane, Norwich NR4 7UH, UK
    Cell Mol Life Sci 66:3755-75. 2009
  4. pmc SAW: breaking down barriers between art and science
    Anne Osbourn
    John Innes Centre, Norwich Research Park, Norwich, United Kingdom
    PLoS Biol 6:e211. 2008
  5. ncbi request reprint The poetry of science
    Anne Osbourn
    Department of Metabolic Biology, John Innes Centre, Colney Lane, Norwich NR4 7UH, UK
    Nat Rev Microbiol 4:77-80. 2006
  6. pmc Formation of plant metabolic gene clusters within dynamic chromosomal regions
    Ben Field
    Department of Metabolic Biology, John Innes Centre, Norwich NR4 7UH, United Kingdom
    Proc Natl Acad Sci U S A 108:16116-21. 2011
  7. doi request reprint Metabolic diversification--independent assembly of operon-like gene clusters in different plants
    Ben Field
    Department of Metabolic Biology, John Innes Centre, Colney Lane, Norwich NR4 7UH, UK
    Science 320:543-7. 2008
  8. ncbi request reprint Molecular cloning and characterization of triterpene synthases from Medicago truncatula and Lotus japonicus
    Inaki Iturbe-Ormaetxe
    Sainsbury Laboratory, John Innes Centre, Colney Lane, Norwich NR4 7UH, U K
    Plant Mol Biol 51:731-43. 2003
  9. doi request reprint High throughput screening of mutants of oat that are defective in triterpene synthesis
    Bo Qin
    Sainsbury Laboratory, Norwich NR4 7UH, UK
    Phytochemistry 71:1245-52. 2010
  10. ncbi request reprint The rice leaf blast pathogen undergoes developmental processes typical of root-infecting fungi
    Ane Sesma
    The Sainsbury Laboratory, John Innes Center, Norwich, UK
    Nature 431:582-6. 2004

Collaborators

Detail Information

Publications13

  1. doi request reprint The saponins: polar isoprenoids with important and diverse biological activities
    Anne Osbourn
    Department of Metabolic Biology, John Innes Centre, Norwich Research Park, UK
    Nat Prod Rep 28:1261-8. 2011
    ..This review will focus on the biological activity of some of the best-studied examples of saponins, on the relationship between structure and function, and on prospects for synthesis of ‘‘designer’’ saponins...
  2. doi request reprint Secondary metabolic gene clusters: evolutionary toolkits for chemical innovation
    Anne Osbourn
    Department of Metabolic Biology, John Innes Centre, Norwich NR4 7UH, UK
    Trends Genet 26:449-57. 2010
    ..It could also facilitate the development of crop plants with enhanced pest or disease resistance, improved nutritional qualities and/or elevated levels of high-value products...
  3. pmc Operons
    Anne E Osbourn
    Department of Metabolic Biology, John Innes Centre, Colney Lane, Norwich NR4 7UH, UK
    Cell Mol Life Sci 66:3755-75. 2009
    ..The aim of this article is to review features of functional gene clusters in prokaryotes and eukaryotes and the significance of clustering for effective function...
  4. pmc SAW: breaking down barriers between art and science
    Anne Osbourn
    John Innes Centre, Norwich Research Park, Norwich, United Kingdom
    PLoS Biol 6:e211. 2008
  5. ncbi request reprint The poetry of science
    Anne Osbourn
    Department of Metabolic Biology, John Innes Centre, Colney Lane, Norwich NR4 7UH, UK
    Nat Rev Microbiol 4:77-80. 2006
    ..I have a keen interest in creative writing and had written a few short stories. This was a formidable but thrilling challenge. During my adventure, I realized that, in many ways, I was coming home...
  6. pmc Formation of plant metabolic gene clusters within dynamic chromosomal regions
    Ben Field
    Department of Metabolic Biology, John Innes Centre, Norwich NR4 7UH, United Kingdom
    Proc Natl Acad Sci U S A 108:16116-21. 2011
    ..We conclude that common mechanisms are likely to underlie the assembly and control of operon-like gene clusters in plants...
  7. doi request reprint Metabolic diversification--independent assembly of operon-like gene clusters in different plants
    Ben Field
    Department of Metabolic Biology, John Innes Centre, Colney Lane, Norwich NR4 7UH, UK
    Science 320:543-7. 2008
    ..Thus, selection pressure may act during the formation of certain plant metabolic pathways to drive gene clustering...
  8. ncbi request reprint Molecular cloning and characterization of triterpene synthases from Medicago truncatula and Lotus japonicus
    Inaki Iturbe-Ormaetxe
    Sainsbury Laboratory, John Innes Centre, Colney Lane, Norwich NR4 7UH, U K
    Plant Mol Biol 51:731-43. 2003
    ..truncatula and pea differ in different plant tissues and during nodulation, suggesting that these enzymes may have distinct roles in plant physiology and development...
  9. doi request reprint High throughput screening of mutants of oat that are defective in triterpene synthesis
    Bo Qin
    Sainsbury Laboratory, Norwich NR4 7UH, UK
    Phytochemistry 71:1245-52. 2010
    ....
  10. ncbi request reprint The rice leaf blast pathogen undergoes developmental processes typical of root-infecting fungi
    Ane Sesma
    The Sainsbury Laboratory, John Innes Center, Norwich, UK
    Nature 431:582-6. 2004
    ..Gene-for-gene type specific disease resistance that is effective against rice blast in leaves also operates in roots. These findings have significant implications for fungal development, epidemiology, plant breeding and disease control...
  11. ncbi request reprint Saponins in cereals
    Anne E Osbourn
    Sainsbury Laboratory, John Innes Centre, Colney Lane, Norwich NR4 7UH, UK
    Phytochemistry 62:1-4. 2003
    ..These genes may also have potential for the development of improved disease resistance in cultivated cereals...
  12. ncbi request reprint Biosynthesis of triterpenoid saponins in plants
    Kosmas Haralampidis
    Sainsbury Laboratory, John Innes Centre, Norwich, UK
    Adv Biochem Eng Biotechnol 75:31-49. 2002
    ..Progress has also been made in the characterisation of saponin glucosyltransferases. This review outlines these developments, with particular emphasis on triterpenoid saponins...
  13. ncbi request reprint 2003 Asilomar meeting report
    N Ronald Morris
    John Innes Centre, Sainsbury Laboratory, Norwich Research Park, Colney Lane, Norwich NR4 7UH, UK
    Fungal Genet Biol 41:109-14. 2004