D J Moore
Affiliation: Institute for Animal Health
- Regional and cellular distribution of the P2Y(1) purinergic receptor in the human brain: striking neuronal localisationD Moore
Department of Neurobiology, The Babraham Institute, Babraham, Cambridge, CB2 4AT, United Kingdom
J Comp Neurol 421:374-84. 2000..The neuronal localisation of this receptor points towards a possible role in neurotransmission, and also highlights a major role for extracellular nucleotides as signaling molecules within the brain...
- Expression pattern of human P2Y receptor subtypes: a quantitative reverse transcription-polymerase chain reaction studyD J Moore
Neurobiology Programme, The Babraham Institute, Cambridege, UK
Biochim Biophys Acta 1521:107-19. 2001..Our extensive expression data indicate the many potentially important roles of P2Y receptors throughout the human body, and will help in elucidating the physiological function of each receptor subtype in a wide variety of human systems...
- Human Ntera-2/D1 neuronal progenitor cells endogenously express a functional P2Y1 receptorD J Moore
Neurobiology Programme, The Babraham Institute, Babraham, Cambridge CB2 4AT, UK
Neuropharmacology 43:966-78. 2002..NT-2 cells, therefore, provide a useful neuronal-like cellular model for studying the precise signalling pathways and physiological responses mediated by a native P2Y(1) receptor...
- AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1A I Muir
Department of Discovery Biology, GlaxoSmithKline, New Frontiers Science Park, Harlow, Essex CM19 5AW, United Kingdom
J Biol Chem 276:28969-75. 2001..The biological significance of these expression patterns and the nature of the putative cognate ligand for AXOR12 are discussed...
- Inverse agonist activity at the alpha(2A)-adrenergic receptorS M Wade
Department of Pharmacology, The University of Michigan, Ann Arbor, Michigan, USA
Mol Pharmacol 59:532-42. 2001....