A Matakidou

Summary

Affiliation: Institute of Cancer Research
Country: UK

Publications

  1. ncbi TP53 polymorphisms and lung cancer risk: a systematic review and meta-analysis
    A Matakidou
    Section of Cancer Genetics, Institute of Cancer Research, Sutton SM2 5NG, UK
    Mutagenesis 18:377-85. 2003
  2. ncbi Case-control study of familial lung cancer risks in UK women
    Athena Matakidou
    Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey, United Kingdom
    Int J Cancer 116:445-50. 2005
  3. pmc Systematic review of the relationship between family history and lung cancer risk
    A Matakidou
    Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey, UK
    Br J Cancer 93:825-33. 2005
  4. pmc Prognostic significance of folate metabolism polymorphisms for lung cancer
    A Matakidou
    Section of Cancer Genetics, Institute of Cancer Research, Brookes Lawley Building, Sutton, Surrey SM2 5NG, UK
    Br J Cancer 97:247-52. 2007
  5. pmc Further observations on the relationship between the FGFR4 Gly388Arg polymorphism and lung cancer prognosis
    A Matakidou
    Section of Cancer Genetics, Institute of Cancer Research, Surrey, UK
    Br J Cancer 96:1904-7. 2007
  6. pmc Time and chemotherapy treatment trends in the treatment of elderly patients (age >/=70 years) with small cell lung cancer
    T Yau
    Lung Unit, Royal Marsden Hospital, Downs Road, Sutton, Surrey SM2 5PT, UK
    Br J Cancer 94:18-21. 2006
  7. ncbi Lack of evidence that p53 Arg72Pro influences lung cancer prognosis: an analysis of survival in 619 female patients
    Athena Matakidou
    Section of Cancer Genetics, Brookes Lawley Building, Institute of Cancer Research, Sutton, Surrey SM2 5NG, UK
    Lung Cancer 57:207-12. 2007
  8. pmc Variants in the GH-IGF axis confer susceptibility to lung cancer
    Matthew F Rudd
    Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey, UK
    Genome Res 16:693-701. 2006
  9. ncbi Evaluation of xeroderma pigmentosum XPA, XPC, XPD, XPF, XPB, XPG and DDB2 genes in familial early-onset lung cancer predisposition
    Athena Matakidou
    Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey, United Kingdom
    Int J Cancer 119:964-7. 2006
  10. ncbi Thymidylate synthase expression and prognosis in colorectal cancer: a systematic review and meta-analysis
    Sanjay Popat
    Section of Cancer Genetics, Institute of Cancer Research, Sutton SM2 5NG, UK
    J Clin Oncol 22:529-36. 2004

Collaborators

Detail Information

Publications14

  1. ncbi TP53 polymorphisms and lung cancer risk: a systematic review and meta-analysis
    A Matakidou
    Section of Cancer Genetics, Institute of Cancer Research, Sutton SM2 5NG, UK
    Mutagenesis 18:377-85. 2003
    ..Additional well-designed studies based on sample sizes commensurate with the detection of small genotypic risks may allow a more definitive conclusion...
  2. ncbi Case-control study of familial lung cancer risks in UK women
    Athena Matakidou
    Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey, United Kingdom
    Int J Cancer 116:445-50. 2005
    ..23; 95% CI, 0.65-2.31). Results confirm previous findings and support the role of a familial predisposition to lung cancer...
  3. pmc Systematic review of the relationship between family history and lung cancer risk
    A Matakidou
    Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey, UK
    Br J Cancer 93:825-33. 2005
    ..The limitations of the currently published epidemiological studies to infer genetic susceptibility are discussed...
  4. pmc Prognostic significance of folate metabolism polymorphisms for lung cancer
    A Matakidou
    Section of Cancer Genetics, Institute of Cancer Research, Brookes Lawley Building, Sutton, Surrey SM2 5NG, UK
    Br J Cancer 97:247-52. 2007
    ..36; 1.06-1.75). While there is evidence that variation in the folate metabolism genes may influence prognosis from lung cancer, current data are insufficiently robust to distinguish individual patient outcome...
  5. pmc Further observations on the relationship between the FGFR4 Gly388Arg polymorphism and lung cancer prognosis
    A Matakidou
    Section of Cancer Genetics, Institute of Cancer Research, Surrey, UK
    Br J Cancer 96:1904-7. 2007
    ....
  6. pmc Time and chemotherapy treatment trends in the treatment of elderly patients (age >/=70 years) with small cell lung cancer
    T Yau
    Lung Unit, Royal Marsden Hospital, Downs Road, Sutton, Surrey SM2 5PT, UK
    Br J Cancer 94:18-21. 2006
    ..This change is probably multifactorial and may be due to the increased use of platinum-based treatment and improved supportive care...
  7. ncbi Lack of evidence that p53 Arg72Pro influences lung cancer prognosis: an analysis of survival in 619 female patients
    Athena Matakidou
    Section of Cancer Genetics, Brookes Lawley Building, Institute of Cancer Research, Sutton, Surrey SM2 5NG, UK
    Lung Cancer 57:207-12. 2007
    ....
  8. pmc Variants in the GH-IGF axis confer susceptibility to lung cancer
    Matthew F Rudd
    Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey, UK
    Genome Res 16:693-701. 2006
    ..0205). Our study provides evidence that inherited predisposition to lung cancer is in part mediated through low-penetrance alleles and specifically identifies variants in GH-IGF and DNA damage-response pathways with risk of lung cancer...
  9. ncbi Evaluation of xeroderma pigmentosum XPA, XPC, XPD, XPF, XPB, XPG and DDB2 genes in familial early-onset lung cancer predisposition
    Athena Matakidou
    Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey, United Kingdom
    Int J Cancer 119:964-7. 2006
    ..Two of the novel missense changes are predicted to be functionally deleterious. Our findings are compatible with XP heterozygosity being a risk factor for lung cancer susceptibility...
  10. ncbi Thymidylate synthase expression and prognosis in colorectal cancer: a systematic review and meta-analysis
    Sanjay Popat
    Section of Cancer Genetics, Institute of Cancer Research, Sutton SM2 5NG, UK
    J Clin Oncol 22:529-36. 2004
    ..To derive a more precise estimate of the prognostic significance of TS expression, we have reviewed published studies and carried out a meta-analysis...
  11. pmc Identification of low penetrance alleles for lung cancer: the GEnetic Lung CAncer Predisposition Study (GELCAPS)
    Tim Eisen
    Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey, SM2 5NG, UK
    BMC Cancer 8:244. 2008
    ....
  12. ncbi Risk of non-medullary thyroid cancer influenced by polymorphic variation in the thyroglobulin gene
    Athena Matakidou
    Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey SM2 5NG, UK
    Carcinogenesis 25:369-73. 2004
    ..2-3.3), respectively. Although the risk of NMTC associated with the TgQ2511R R-allele is modest, its high prevalence in the general population suggests it may make a significant contribution to the incidence of NMTC...
  13. ncbi Genetic variation in the DNA repair genes is predictive of outcome in lung cancer
    Athena Matakidou
    Section of Cancer Genetics, Institute of Cancer Research, Sutton, UK
    Hum Mol Genet 16:2333-40. 2007
    ..Our data indicate that the pathway-based approach has the potential to generate prognostic markers of clinical outcome...
  14. pmc Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1
    Christopher I Amos
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Nat Genet 40:616-22. 2008
    ..Haplotype analysis was consistent with there being a single risk variant in this region. We conclude that variation in a region of 15q25.1 containing nicotinic acetylcholine receptors genes contributes to lung cancer risk...