Research Topics
Genomes and Genes | A MatakidouSummaryAffiliation: Institute of Cancer Research Country: UK Publications
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Detail Information
Publications
TP53 polymorphisms and lung cancer risk: a systematic review and meta-analysisA Matakidou
Section of Cancer Genetics, Institute of Cancer Research, Sutton SM2 5NG, UK
Mutagenesis 18:377-85. 2003..Additional well-designed studies based on sample sizes commensurate with the detection of small genotypic risks may allow a more definitive conclusion...- Case-control study of familial lung cancer risks in UK womenAthena Matakidou
Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey, United Kingdom
Int J Cancer 116:445-50. 2005..23; 95% CI, 0.65-2.31). Results confirm previous findings and support the role of a familial predisposition to lung cancer... 
Systematic review of the relationship between family history and lung cancer riskA Matakidou
Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey, UK
Br J Cancer 93:825-33. 2005..The limitations of the currently published epidemiological studies to infer genetic susceptibility are discussed...- Prognostic significance of folate metabolism polymorphisms for lung cancerA Matakidou
Section of Cancer Genetics, Institute of Cancer Research, Brookes Lawley Building, Sutton, Surrey SM2 5NG, UK
Br J Cancer 97:247-52. 2007..36; 1.06-1.75). While there is evidence that variation in the folate metabolism genes may influence prognosis from lung cancer, current data are insufficiently robust to distinguish individual patient outcome... - Further observations on the relationship between the FGFR4 Gly388Arg polymorphism and lung cancer prognosisA Matakidou
Section of Cancer Genetics, Institute of Cancer Research, Surrey, UK
Br J Cancer 96:1904-7. 2007.... - Time and chemotherapy treatment trends in the treatment of elderly patients (age >/=70 years) with small cell lung cancerT Yau
Lung Unit, Royal Marsden Hospital, Downs Road, Sutton, Surrey SM2 5PT, UK
Br J Cancer 94:18-21. 2006..This change is probably multifactorial and may be due to the increased use of platinum-based treatment and improved supportive care... - Lack of evidence that p53 Arg72Pro influences lung cancer prognosis: an analysis of survival in 619 female patientsAthena Matakidou
Section of Cancer Genetics, Brookes Lawley Building, Institute of Cancer Research, Sutton, Surrey SM2 5NG, UK
Lung Cancer 57:207-12. 2007.... - Variants in the GH-IGF axis confer susceptibility to lung cancerMatthew F Rudd
Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey, UK
Genome Res 16:693-701. 2006..0205). Our study provides evidence that inherited predisposition to lung cancer is in part mediated through low-penetrance alleles and specifically identifies variants in GH-IGF and DNA damage-response pathways with risk of lung cancer... - Evaluation of xeroderma pigmentosum XPA, XPC, XPD, XPF, XPB, XPG and DDB2 genes in familial early-onset lung cancer predispositionAthena Matakidou
Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey, United Kingdom
Int J Cancer 119:964-7. 2006..Two of the novel missense changes are predicted to be functionally deleterious. Our findings are compatible with XP heterozygosity being a risk factor for lung cancer susceptibility... - Thymidylate synthase expression and prognosis in colorectal cancer: a systematic review and meta-analysisSanjay Popat
Section of Cancer Genetics, Institute of Cancer Research, Sutton SM2 5NG, UK
J Clin Oncol 22:529-36. 2004..To derive a more precise estimate of the prognostic significance of TS expression, we have reviewed published studies and carried out a meta-analysis... - Identification of low penetrance alleles for lung cancer: the GEnetic Lung CAncer Predisposition Study (GELCAPS)Tim Eisen
Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey, SM2 5NG, UK
BMC Cancer 8:244. 2008.... - Risk of non-medullary thyroid cancer influenced by polymorphic variation in the thyroglobulin geneAthena Matakidou
Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey SM2 5NG, UK
Carcinogenesis 25:369-73. 2004..2-3.3), respectively. Although the risk of NMTC associated with the TgQ2511R R-allele is modest, its high prevalence in the general population suggests it may make a significant contribution to the incidence of NMTC... - Genetic variation in the DNA repair genes is predictive of outcome in lung cancerAthena Matakidou
Section of Cancer Genetics, Institute of Cancer Research, Sutton, UK
Hum Mol Genet 16:2333-40. 2007..Our data indicate that the pathway-based approach has the potential to generate prognostic markers of clinical outcome... - Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1Christopher I Amos
Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Nat Genet 40:616-22. 2008..Haplotype analysis was consistent with there being a single risk variant in this region. We conclude that variation in a region of 15q25.1 containing nicotinic acetylcholine receptors genes contributes to lung cancer risk...