Wai M Liu

Summary

Affiliation: Institute of Cancer Research
Country: UK

Publications

  1. ncbi request reprint Effect of haemopoietic growth factors on cancer cell lines and their role in chemosensitivity
    Wai Man Liu
    New Drug Study Group, Barry Reed Oncology Laboratory, St Bartholomew s Hospital, London, UK
    Oncogene 23:981-90. 2004
  2. ncbi request reprint The in vitro effects of CRE-decoy oligonucleotides in combination with conventional chemotherapy in colorectal cancer cell lines
    Wai M Liu
    New Drug Study Group, Barry Reed Oncology Laboratory, St Bartholomew s Hospital, London, UK
    Eur J Biochem 271:2773-81. 2004
  3. doi request reprint In vitro study of the anti-cancer effects of artemisone alone or in combination with other chemotherapeutic agents
    Andrew M Gravett
    Department of Oncology, Division of Cellular and Molecular Medicine, St George s, University of London, London, UK
    Cancer Chemother Pharmacol 67:569-77. 2011
  4. doi request reprint Enhancing the in vitro cytotoxic activity of Delta9-tetrahydrocannabinol in leukemic cells through a combinatorial approach
    Wai M Liu
    Department of Oncology, St George s University of London, Jenner Wing, London, UK
    Leuk Lymphoma 49:1800-9. 2008
  5. doi request reprint A microarray study of altered gene expression in colorectal cancer cells after treatment with immunomodulatory drugs: differences in action in vivo and in vitro
    Wai M Liu
    Department of Oncology, Division of Cellular and Molecular Medicine, St George s University of London, 2nd Floor, Jenner Wing, London, SW17 0RE, UK
    Mol Biol Rep 37:1801-14. 2010
  6. doi request reprint The potential beneficial effects of drugs on the immune response to vaccination
    Wai M Liu
    Department of Oncology, Division of Clinical Sciences, St George s, University of London, London, UK
    Semin Oncol 39:340-7. 2012
  7. ncbi request reprint s-thalidomide has a greater effect on apoptosis than angiogenesis in a multiple myeloma cell line
    Wai M Liu
    1New Drug Study Group, Barry Reed Oncology Laboratory, St Bartholomew s Hospital, London, UK
    Hematol J 5:247-54. 2004
  8. ncbi request reprint Cannabis-derived substances in cancer therapy--an emerging anti-inflammatory role for the cannabinoids
    Wai M Liu
    Division of Cellular and Molecular Medicine Oncology, St George s University of London, London, UK
    Curr Clin Pharmacol 5:281-7. 2010
  9. ncbi request reprint The schedule-dependent effects of etoposide in leukaemic cell lines: a function of concentration and duration
    Wai M Liu
    New Drug Study Group, Department of Medical Oncology, St Bartholomew s Hospital, 38 Little Britain, West Smithfield, London, EC1A 7BE, UK
    Cancer Chemother Pharmacol 51:291-6. 2003
  10. ncbi request reprint Enhancing the cytotoxic activity of novel targeted therapies--is there a role for a combinatorial approach?
    Wai Man Liu
    Department of Oncology, Division of Cellular and Molecular Medicine, St George s, University of London, London, UK
    Curr Clin Pharmacol 3:108-17. 2008

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Effect of haemopoietic growth factors on cancer cell lines and their role in chemosensitivity
    Wai Man Liu
    New Drug Study Group, Barry Reed Oncology Laboratory, St Bartholomew s Hospital, London, UK
    Oncogene 23:981-90. 2004
    ..Conversely, our results also suggest that GFs are safe to use in chemotherapeutic regimens if the cancer cells do not overexpress the particular receptor...
  2. ncbi request reprint The in vitro effects of CRE-decoy oligonucleotides in combination with conventional chemotherapy in colorectal cancer cell lines
    Wai M Liu
    New Drug Study Group, Barry Reed Oncology Laboratory, St Bartholomew s Hospital, London, UK
    Eur J Biochem 271:2773-81. 2004
    ..Clinically, the cytostatic ability of CDO could improve and enhance the antiproliferative effects of conventional cytotoxic agents...
  3. doi request reprint In vitro study of the anti-cancer effects of artemisone alone or in combination with other chemotherapeutic agents
    Andrew M Gravett
    Department of Oncology, Division of Cellular and Molecular Medicine, St George s, University of London, London, UK
    Cancer Chemother Pharmacol 67:569-77. 2011
    ..We have investigated the role of artemisone (ATM), a novel derivative of artemisinin (ART) in a cancer setting both alone and in combination with established chemotherapeutic agents...
  4. doi request reprint Enhancing the in vitro cytotoxic activity of Delta9-tetrahydrocannabinol in leukemic cells through a combinatorial approach
    Wai M Liu
    Department of Oncology, St George s University of London, Jenner Wing, London, UK
    Leuk Lymphoma 49:1800-9. 2008
    ..Overall, these results demonstrate for the first time that a combination approach with THC and established cytotoxic agents may enhance cell death in vitro. Additionally the MAPK/ERK pathway appears responsible in part for these effects...
  5. doi request reprint A microarray study of altered gene expression in colorectal cancer cells after treatment with immunomodulatory drugs: differences in action in vivo and in vitro
    Wai M Liu
    Department of Oncology, Division of Cellular and Molecular Medicine, St George s University of London, 2nd Floor, Jenner Wing, London, SW17 0RE, UK
    Mol Biol Rep 37:1801-14. 2010
    ..Overall, these microarray studies highlighted the diversity of this class of drug, which have effects ranging from cell signalling to translation initiation...
  6. doi request reprint The potential beneficial effects of drugs on the immune response to vaccination
    Wai M Liu
    Department of Oncology, Division of Clinical Sciences, St George s, University of London, London, UK
    Semin Oncol 39:340-7. 2012
    ..With the first approval for a vaccine-based therapy for prostate cancer, we propose that many more vaccines will be able to achieve approval, especially when combined with the optimal chemotherapy and/or immunomodulatory drug schedule...
  7. ncbi request reprint s-thalidomide has a greater effect on apoptosis than angiogenesis in a multiple myeloma cell line
    Wai M Liu
    1New Drug Study Group, Barry Reed Oncology Laboratory, St Bartholomew s Hospital, London, UK
    Hematol J 5:247-54. 2004
    ..Additionally, a dramatic decrease in Bcl-2 expression with s-thalidomide suggests a possible enhancement of cytotoxic effect if combined with other cytotoxic agents...
  8. ncbi request reprint Cannabis-derived substances in cancer therapy--an emerging anti-inflammatory role for the cannabinoids
    Wai M Liu
    Division of Cellular and Molecular Medicine Oncology, St George s University of London, London, UK
    Curr Clin Pharmacol 5:281-7. 2010
    ..Furthermore, the relationship between chronic inflammation and cancer, and how cannabinoids can impact this relationship will be described...
  9. ncbi request reprint The schedule-dependent effects of etoposide in leukaemic cell lines: a function of concentration and duration
    Wai M Liu
    New Drug Study Group, Department of Medical Oncology, St Bartholomew s Hospital, 38 Little Britain, West Smithfield, London, EC1A 7BE, UK
    Cancer Chemother Pharmacol 51:291-6. 2003
    ..Etoposide is a commonly used anticancer agent that is highly schedule-dependent. The in vitro activity of etoposide (0-10 microM) was investigated in a panel of leukaemic cell lines...
  10. ncbi request reprint Enhancing the cytotoxic activity of novel targeted therapies--is there a role for a combinatorial approach?
    Wai Man Liu
    Department of Oncology, Division of Cellular and Molecular Medicine, St George s, University of London, London, UK
    Curr Clin Pharmacol 3:108-17. 2008
    ....
  11. ncbi request reprint Cannabis-induced cytotoxicity in leukemic cell lines: the role of the cannabinoid receptors and the MAPK pathway
    Thomas Powles
    New Drug Study Group, St Bartholomew s Hospital, London, United Kingdom
    Blood 105:1214-21. 2005
    ..Both apoptosis and gene expression changes were altered independent of p53 and the CB-Rs...