Dow Mu Koh

Summary

Affiliation: Institute of Cancer Research
Country: UK

Publications

  1. ncbi request reprint New horizons in oncologic imaging
    Dow Mu Koh
    Academic Department of Radiology, Royal Marsden Hospital, Sutton, United Kingdom
    N Engl J Med 348:2487-8. 2003
  2. ncbi request reprint Cross-sectional imaging of nodal metastases in the abdomen and pelvis
    D M Koh
    Academic Department of Radiology, Royal Marsden Hospital, Downs Road, Sutton SM2 5PT, UK
    Abdom Imaging 31:632-43. 2006
  3. ncbi request reprint Nodal staging in rectal cancer
    D M Koh
    Academic Department of Radiology, Royal Marsden Hospital, Downs Road, Sutton SM2 5PT, UK
    Abdom Imaging 31:652-9. 2006
  4. ncbi request reprint Diagnostic accuracy of rim and segmental MRI enhancement of colorectal hepatic metastasis after administration of mangafodipir trisodium
    Dow Mu Koh
    Academic Department of Radiology, Royal Marsden Hospital, Downs Rd, Sutton, Surrey, United Kingdom SM2 5PT
    AJR Am J Roentgenol 188:W154-61. 2007
  5. ncbi request reprint Imaging hypoxia in tumours with advanced MRI
    J M Price
    Cancer Research UK and EPSRC Cancer Imaging Centre, Division of Radiotherapy and Imaging, Institute of Cancer Research, Sutton, UK
    Q J Nucl Med Mol Imaging 57:257-70. 2013
  6. doi request reprint Combination of chemical suppression techniques for dual suppression of fat and silicone at diffusion-weighted MR imaging in women with breast implants
    Dow Mu Koh
    Department of Radiology, Royal Marsden Hospital, Downs Road, SM2 5PT, Sutton, UK
    Eur Radiol 22:2648-53. 2012
  7. doi request reprint Diffusion-weighted imaging of the male pelvis
    Dow Mu Koh
    Department of Radiology, Royal Marsden Hospital, Royal Marsden NHS Foundation Trust, Sutton, UK
    Radiol Clin North Am 50:1127-44. 2012
  8. doi request reprint Whole-body diffusion-weighted MRI: tips, tricks, and pitfalls
    Dow Mu Koh
    Department of Radiology, Royal Marsden Hospital, Downs Rd, Sutton, Surrey SM25PT, UK
    AJR Am J Roentgenol 199:252-62. 2012
  9. pmc Combining diffusion-weighted MRI with Gd-EOB-DTPA-enhanced MRI improves the detection of colorectal liver metastases
    D M Koh
    Department of Radiology, Royal Marsden NHS Foundation Trust, Sutton, UK
    Br J Radiol 85:980-9. 2012
  10. doi request reprint Nanoparticles in rectal cancer imaging
    Dow Mu Koh
    Department of Radiology, Royal Marsden Hospital, Surrey, UK
    Cancer Biomark 5:89-98. 2009

Collaborators

Detail Information

Publications50

  1. ncbi request reprint New horizons in oncologic imaging
    Dow Mu Koh
    Academic Department of Radiology, Royal Marsden Hospital, Sutton, United Kingdom
    N Engl J Med 348:2487-8. 2003
  2. ncbi request reprint Cross-sectional imaging of nodal metastases in the abdomen and pelvis
    D M Koh
    Academic Department of Radiology, Royal Marsden Hospital, Downs Road, Sutton SM2 5PT, UK
    Abdom Imaging 31:632-43. 2006
    ..An appreciation of normal structures that may simulate nodal disease is also important. The potential for further improving nodal staging accuracy by positron emission tomography and magnetic resonance lymphography is discussed...
  3. ncbi request reprint Nodal staging in rectal cancer
    D M Koh
    Academic Department of Radiology, Royal Marsden Hospital, Downs Road, Sutton SM2 5PT, UK
    Abdom Imaging 31:652-9. 2006
    ..The use of morphological criteria instead of size criteria has been shown to improve nodal staging by MRI. The potential role of magnetic resonance lymphography and PET imaging in further improving nodal staging accuracy is discussed...
  4. ncbi request reprint Diagnostic accuracy of rim and segmental MRI enhancement of colorectal hepatic metastasis after administration of mangafodipir trisodium
    Dow Mu Koh
    Academic Department of Radiology, Royal Marsden Hospital, Downs Rd, Sutton, Surrey, United Kingdom SM2 5PT
    AJR Am J Roentgenol 188:W154-61. 2007
    ..The purpose of this study was to determine the diagnostic accuracy of rim and segmental MRI enhancement of hepatic metastasis of colorectal cancer after administration of mangafodipir trisodium (MnDPDP)...
  5. ncbi request reprint Imaging hypoxia in tumours with advanced MRI
    J M Price
    Cancer Research UK and EPSRC Cancer Imaging Centre, Division of Radiotherapy and Imaging, Institute of Cancer Research, Sutton, UK
    Q J Nucl Med Mol Imaging 57:257-70. 2013
    ....
  6. doi request reprint Combination of chemical suppression techniques for dual suppression of fat and silicone at diffusion-weighted MR imaging in women with breast implants
    Dow Mu Koh
    Department of Radiology, Royal Marsden Hospital, Downs Road, SM2 5PT, Sutton, UK
    Eur Radiol 22:2648-53. 2012
    ..We describe a combined fat and chemical suppression scheme to achieve dual suppression of fat and silicone, thereby improving the quality of diffusion-weighted images in women with breast implants...
  7. doi request reprint Diffusion-weighted imaging of the male pelvis
    Dow Mu Koh
    Department of Radiology, Royal Marsden Hospital, Royal Marsden NHS Foundation Trust, Sutton, UK
    Radiol Clin North Am 50:1127-44. 2012
    ..There is growing interest in applying quantitative DWI for the assessment of tumor treatment response. In addition, the technique seems promising for the evaluation of metastatic nodal and bone disease in the pelvis...
  8. doi request reprint Whole-body diffusion-weighted MRI: tips, tricks, and pitfalls
    Dow Mu Koh
    Department of Radiology, Royal Marsden Hospital, Downs Rd, Sutton, Surrey SM25PT, UK
    AJR Am J Roentgenol 199:252-62. 2012
    ..We include practical tips and tricks to optimize image quality and reduce artifacts. The interpretative pitfalls are enumerated, and potential challenges are highlighted...
  9. pmc Combining diffusion-weighted MRI with Gd-EOB-DTPA-enhanced MRI improves the detection of colorectal liver metastases
    D M Koh
    Department of Radiology, Royal Marsden NHS Foundation Trust, Sutton, UK
    Br J Radiol 85:980-9. 2012
    ....
  10. doi request reprint Nanoparticles in rectal cancer imaging
    Dow Mu Koh
    Department of Radiology, Royal Marsden Hospital, Surrey, UK
    Cancer Biomark 5:89-98. 2009
    ..In this article, we discuss the challenges to accurate nodal staging of patients with rectal cancer, and demonstrate how USPIO may be applied to rectal cancer imaging to identify nodal involvement...
  11. doi request reprint Evaluating mesorectal lymph nodes in rectal cancer before and after neoadjuvant chemoradiation using thin-section T2-weighted magnetic resonance imaging
    Dow Mu Koh
    Academic Department of Radiology, The Royal Marsden Hospital, Sutton, United Kingdom
    Int J Radiat Oncol Biol Phys 71:456-61. 2008
    ....
  12. doi request reprint Detection of colorectal hepatic metastases using MnDPDP MR imaging and diffusion-weighted imaging (DWI) alone and in combination
    D M Koh
    Cancer Research UK Clinical Magnetic Resonance Research Group, Institute of Cancer Research, Sutton, UK
    Eur Radiol 18:903-10. 2008
    ..5). Combination of MnDPDP MR imaging and DWI resulted in the highest diagnostic accuracy and can increase sensitivity without loss in specificity...
  13. doi request reprint Pelvic phased-array MR imaging of anal carcinoma before and after chemoradiation
    D M Koh
    Academic Department of Radiology, Royal Marsden Hospital, Sutton, UK
    Br J Radiol 81:91-8. 2008
    ..After treatment, a decrease in tumour size accompanied by reduction and stability of the MR T(2) signal characteristics at 1 year after chemoradiation treatment was associated with favourable outcome...
  14. ncbi request reprint Practical aspects of assessing tumors using clinical diffusion-weighted imaging in the body
    Dow Mu Koh
    CR UK Clinical Magnetic Resonance Research Group, Institute of Cancer Research and Academic Department of Radiology, Royal Marsden Hospital, Sutton, UK
    Magn Reson Med Sci 6:211-24. 2007
    ..We illustrate the potential use of these techniques to detect and characterize tumors and to monitor treatment effects...
  15. pmc Critical questions in the imaging of colorectal hepatic metastases
    Dow Mu Koh
    Department of Radiology, Royal Marsden NHS Foundation Trust, Sutton, UK
    Cancer Imaging 8:S69-78. 2008
    ....
  16. ncbi request reprint Reproducibility and changes in the apparent diffusion coefficients of solid tumours treated with combretastatin A4 phosphate and bevacizumab in a two-centre phase I clinical trial
    Dow Mu Koh
    Department of Radiology, Royal Marsden Hospital, Downs Road, SM25PT Sutton, UK
    Eur Radiol 19:2728-38. 2009
    ..05). ADC measurements were highly reproducible in a two-centre clinical trial setting and appear promising for evaluating the effects of drugs that target tumour vasculature...
  17. ncbi request reprint Distribution of mesorectal lymph nodes in rectal cancer: in vivo MR imaging compared with histopathological examination. Initial observations
    D M Koh
    Academic Department of Radiology, Cancer Research UK Magnetic Resonance Group, Institute of Cancer Research, Royal Marsden Hospital, Downs Road, Sutton, SM2 5PT, UK
    Eur Radiol 15:1650-7. 2005
    ..Almost all mesorectal nodes visible on MR imaging were found at the level of tumour or within 5 cm proximal to the tumour. This has implications for the planning of MR imaging and the level of mesorectal transection at surgery...
  18. ncbi request reprint Colorectal hepatic metastases: quantitative measurements using single-shot echo-planar diffusion-weighted MR imaging
    D M Koh
    Cancer Research UK Magnetic Resonance Clinical Research Group, Institute of Cancer Research, Sutton, UK
    Eur Radiol 16:1898-905. 2006
    ..However, the estimated F was found to be lower in metastases compared to liver (P = 0.03, Mann-Whitney test). Colorectal hepatic metastases were characterised by higher ADC1 and ADC2 values, but lower F values compared to liver...
  19. ncbi request reprint Rectal cancer: mesorectal lymph nodes at MR imaging with USPIO versus histopathologic findings--initial observations
    Dow Mu Koh
    Department of Academic Radiology and Medical Statistics, Royal Marsden Hospital, Downs Rd, Sutton SM2 5PT, England
    Radiology 231:91-9. 2004
    ..To compare histopathologic findings with appearances of mesorectal lymph nodes at magnetic resonance (MR) imaging with ultrasmall particles of iron oxide (USPIO) in rectal cancer...
  20. doi request reprint Diagnostic accuracy of nodal enhancement pattern of rectal cancer at MRI enhanced with ultrasmall superparamagnetic iron oxide: findings in pathologically matched mesorectal lymph nodes
    Dow Mu Koh
    Department of Radiology, Royal Marsden Hospital, Sutton, Surrey SM2 5PT, United Kingdom
    AJR Am J Roentgenol 194:W505-13. 2010
    ....
  21. ncbi request reprint Quantitative mapping of hepatic perfusion index using MR imaging: a potential reproducible tool for assessing tumour response to treatment with the antiangiogenic compound BIBF 1120, a potent triple angiokinase inhibitor
    Keiko Miyazaki
    CRUK Clinical Magnetic Resonance Research Group, The Institute of Cancer Research, Royal Marsden Hospital, Downs Road, Sutton, Surrey, SM2 5PT, UK
    Eur Radiol 18:1414-21. 2008
    ..05). This pilot study demonstrates that HPI determined using quantified Gd-DTPA concentration is reproducible and may be useful for monitoring antiangiogenic treatment response of hepatic metastases...
  22. doi request reprint Neuroendocrine tumor liver metastases: use of dynamic contrast-enhanced MR imaging to monitor and predict radiolabeled octreotide therapy response
    Keiko Miyazaki
    Institute of Cancer Research, Cancer Research UK and EPSRC Cancer Imaging Centre, Sutton, Surrey SM2 5NG, England
    Radiology 263:139-48. 2012
    ....
  23. pmc Nodal staging
    Skandadas Ganeshalingam
    Department of Clinical Radiology, Royal Marsden Hospital, Downs Road, Sutton, SM2 5PT, UK
    Cancer Imaging 9:104-11. 2009
    ..The clinical role of positron emission tomography-CT imaging for nodal staging is discussed and emerging imaging techniques that may further improve nodal staging accuracy are surveyed...
  24. ncbi request reprint Predicting response of colorectal hepatic metastasis: value of pretreatment apparent diffusion coefficients
    Dow Mu Koh
    Academic Department of Radiology, Royal Marsden Hospital, Downs Rd, Sutton, Surrey, United Kingdom, SM2 5PT
    AJR Am J Roentgenol 188:1001-8. 2007
    ....
  25. doi request reprint Computed diffusion-weighted MR imaging may improve tumor detection
    Matthew D Blackledge
    Cancer Research UK and Engineering and Physical Sciences Research Council Cancer Imaging Centre, Institute of Cancer Research and Royal Marsden Hospital, Downs Rd, Sutton, Surrey SM2 5PT, England
    Radiology 261:573-81. 2011
    ....
  26. ncbi request reprint The use of 18F-FDG PET/CT in colorectal liver metastases--comparison with CT and liver MRI
    G Kong
    Department of Nuclear Medicine and PET, The Royal Marsden NHS Foundation Trust, Downs Road, Sutton, Surrey SM2 5PT, UK
    Eur J Nucl Med Mol Imaging 35:1323-9. 2008
    ....
  27. ncbi request reprint Assessment of treatment response by total tumor volume and global apparent diffusion coefficient using diffusion-weighted MRI in patients with metastatic bone disease: a feasibility study
    Matthew D Blackledge
    Radiotherapy and Imaging Division, Cancer Research UK and Engineering and Physical Sciences Research Council Cancer Imaging Centre at The Institute of Cancer Research and The Royal Marsden National Health Service Foundation Trust, Sutton, United Kingdom
    PLoS ONE 9:e91779. 2014
    ..Semi-automatic segmentation of WBDWI is feasible for metastatic bone disease in this pilot cohort of 11 patients, and could be used to quantify tumor total diffusion volume and median global ADC for assessing response to treatment. ..
  28. ncbi request reprint Diffusion-weighted MRI in the body: applications and challenges in oncology
    Dow Mu Koh
    Cancer Research UK Clinical Magnetic Resonance Research Group, Institute of Cancer Research, Sutton, Surrey, United Kingdom
    AJR Am J Roentgenol 188:1622-35. 2007
    ..The challenges to widespread adoption of the technique for cancer imaging in the body are discussed...
  29. doi request reprint Optimizing functional parameter accuracy for breath-hold DCE-MRI of liver tumours
    Matthew R Orton
    Cancer Research UK Clinical MR Research Group, Institute of Cancer Research, Sutton, Surrey SM2 5PT, UK
    Phys Med Biol 54:2197-215. 2009
    ..The simulation results show that the protocol consisting of two images per breath-hold is to be preferred as it requires identical patient co-operation, but provides parameter estimates that have superior accuracy and precision...
  30. doi request reprint Whole-body diffusion-weighted MR imaging in cancer: current status and research directions
    Anwar R Padhani
    Paul Strickland Scanner Centre, Mount Vernon Cancer Centre, Rickmansworth Road, Northwood, Middlesex HA6 2RN, England
    Radiology 261:700-18. 2011
    ....
  31. doi request reprint Intravoxel incoherent motion in body diffusion-weighted MRI: reality and challenges
    Dow Mu Koh
    Department of Radiology, Royal Marsden Hospital, Downs Rd, Sutton SM2 5PT, UK
    AJR Am J Roentgenol 196:1351-61. 2011
    ....
  32. doi request reprint Clinical utility of diffusion-weighted magnetic resonance imaging in prostate cancer
    Asim Afaq
    Department of Diagnostic Imaging, Royal Marsden Hospital, London, UK
    BJU Int 108:1716-22. 2011
    ..This mini-review concisely summarises, for clinical managing patients with prostate cancer, the clinical utility of diffusion weighted MRI...
  33. doi request reprint Comparison of free-breathing with navigator-controlled acquisition regimes in abdominal diffusion-weighted magnetic resonance images: Effect on ADC and IVIM statistics
    Neil P Jerome
    CR UK and EPSRC Cancer Imaging Centre, Division of Radiotherapy and Imaging, Institute of Cancer Research, Sutton, Surrey, UK
    J Magn Reson Imaging 39:235-40. 2014
    ..To evaluate the effect on diffusion-weighted image-derived parameters in the apparent diffusion coefficient (ADC) and intra-voxel incoherent motion (IVIM) models from choice of either free-breathing or navigator-controlled acquisition...
  34. pmc Liver-specific contrast agents
    Dow Mu Koh
    Department of Diagnostic Radiology, The Royal Marsden NHS Foundation Trust, Sutton, Surrey, UK
    Cancer Imaging 12:363-4. 2012
    ....
  35. doi request reprint Improved intravoxel incoherent motion analysis of diffusion weighted imaging by data driven Bayesian modeling
    Matthew R Orton
    CR UK and EPSRC Cancer Imaging Centre, Institute of Cancer Research, Sutton, Surrey, UK
    Magn Reson Med 71:411-20. 2014
    ..Use of a Bayesian shrinkage prior approach is, therefore, recommended for intravoxel incoherent motion modeling...
  36. doi request reprint The role of imaging in the diagnosis, staging, and management of testicular cancer
    S Aslam Sohaib
    Department of Diagnostic Radiology, Royal Marsden Hospital, Down Rd, Sutton, Surrey SM2 5PT, England
    AJR Am J Roentgenol 191:387-95. 2008
    ..The objective of this article is to describe recent developments in imaging patients with testicular germ cell tumors (GCTs)...
  37. doi request reprint Imaging studies for germ cell tumors
    S A Sohaib
    Department of Diagnostic Radiology, Royal Marsden Hospital, Down Road, Sutton, Surrey SM2 5PT, England, UK
    Hematol Oncol Clin North Am 25:487-502, vii. 2011
    ..CT remains the main radiologic technique used, although ultrasound, MRI, and positron emission tomography also have specific roles in the clinical management of these patients...
  38. ncbi request reprint Gemcitabine, cisplatin and methylprednisolone chemotherapy (GEM-P) is an effective regimen in patients with poor prognostic primary progressive or multiply relapsed Hodgkin's and non-Hodgkin's lymphoma
    Ian Chau
    Department of Medicine, Royal Marsden Hospital, London, UK
    Br J Haematol 120:970-7. 2003
    ..9-80.5%). In conclusion, GEM-P is a novel combination salvage therapy for poor-prognostic primary progressive or multiply relapsed lymphoma patients. It has clinically significant activity with a favourable toxicity profile...
  39. doi request reprint Fusion of high b-value diffusion-weighted and T2-weighted MR images improves identification of lymph nodes in the pelvis
    N Mir
    Department of Radiology, Royal Marsden NHS Foundation Trust, Surrey, UK
    J Med Imaging Radiat Oncol 54:358-64. 2010
    ..The improved nodal identification may aid treatment planning and further nodal characterisation...
  40. ncbi request reprint Reduced Warburg effect in cancer cells undergoing autophagy: steady- state 1H-MRS and real-time hyperpolarized 13C-MRS studies
    Gigin Lin
    Cancer Research UK and EPSRC Cancer Imaging Centre, Division of Radiotherapy and Imaging, The Institute of Cancer Research and Royal Marsden Hospital, Sutton, Surrey, United Kingdom Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou, College of Medicine, Chang Gung University, Taoyuan, Taiwan
    PLoS ONE 9:e92645. 2014
    ..k(PL) (hyperpolarized (13)C-MRS) and lactate ((1)H-MRS) provide useful biomarkers for the autophagic process, enabling non-invasive monitoring of the Warburg effect...
  41. doi request reprint Perfusion CT vascular parameters do not correlate with immunohistochemically derived microvessel density count in colorectal tumors
    Shwetal Dighe
    Department of Surgery, Mayday University Hospital NHS Trust, Croydon, London, England
    Radiology 268:400-10. 2013
    ....
  42. doi request reprint Informatics in radiology: development of a research PACS for analysis of functional imaging data in clinical research and clinical trials
    Simon J Doran
    Cancer Research UK and EPSRC Cancer Imaging Centre, Institute of Cancer Research, 15 Cotswold Rd, Sutton SM2 5NG, England
    Radiographics 32:2135-50. 2012
    ....
  43. doi request reprint Functional magnetic resonance imaging of the liver: parametric assessments beyond morphology
    Dow Mu Koh
    Department of Radiology, Royal Marsden Hospital, Downs Road, Sutton SM2 5PT, UK
    Magn Reson Imaging Clin N Am 18:565-85, xii. 2010
    ..The challenges widespread adoption of functional MR imaging and the translation of such techniques to high field strengths are also discussed...
  44. ncbi request reprint Changes in functional imaging parameters following induction chemotherapy have important implications for individualised patient-based treatment regimens for advanced head and neck cancer
    Ceri Powell
    The Royal Marsden NHS Trust, Surrey, United Kingdom
    Radiother Oncol 106:112-7. 2013
    ..Understanding the impact of IC on FI parameters is, therefore, essential...
  45. ncbi request reprint Transthoracic US of the chest: clinical uses and applications
    Dow Mu Koh
    Department of Radiology, Chelsea and Westminster Hospital, London SW10 9NH, England
    Radiographics 22:e1. 2002
    ..The use of US in guiding biopsy, thoracocentesis, and other interventional procedures of the lung, pleural space, and mediastinum are also reviewed...
  46. pmc The Relationship Between MR Demonstration of Extramural Venous Invasion and Nodal Disease in Rectal Cancer
    Dow Mu Koh
    Academic Department of Radiology, Royal Marsden Hospital, U K
    Clin Med Oncol 2:267-73. 2008
    ..To investigate the relationship between extramural venous invasion (EMVI) detected at T2-weighted MRI and nodal disease rectal cancer compared with histopathology...
  47. ncbi request reprint Prospective assessment of MRI for imaging retroperitoneal metastases from testicular germ cell tumours
    S A Sohaib
    Department of Radiology, Institute of Cancer Research and Royal Marsden Hospital, Sutton, Surrey, UK
    Clin Radiol 64:362-7. 2009
    ..To determine the sensitivity of magnetic resonance imaging (MRI) in the detection of retroperitoneal lymph nodes in patients with testicular germ cell tumours (TGCT)...
  48. ncbi request reprint Mycobacterial infections: still a millennium bug--the imaging features of mycobacterial infections
    D M Koh
    Department of Radiology, Chelsea and Westminster Hospital, London, UK
    Clin Radiol 56:535-44. 2001
    ..Imaging similarities and differences between the normal and the immunocompromised host will be highlighted...
  49. ncbi request reprint Metastatic intramammary lymph nodes as the primary presenting sign of breast cancer
    E Kouskos
    Breast Unit, Royal Marsden Hospital, NHS Trust, Downs Road, Sutton, Surrey SM2 5PT, UK
    Breast 13:416-20. 2004
    ..IMLNs could be invaded by breast cancer influencing the prognosis and the management of patients. The aim of this study is to present the very rare phenomenon of metastatic involvement of these nodes from an occult breast cancer...
  50. pmc Perfusion magnetic resonance imaging of the liver
    Choon Hua Thng
    Department of Oncologic Imaging, National Cancer Centre, Singapore 169610, Singapore
    World J Gastroenterol 16:1598-609. 2010
    ..Technical standardization and further studies will help to establish and validate perfusion MRI as a clinical imaging modality...