Research Topics
| D P KnightSummaryAffiliation: Institute of Epileptology Country: UK Publications
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Detail Information
Publications
Ultrastructure of insect and spider cocoon silksOsnat Hakimi
Interdisciplinary Research Center in Biomedical Materials, Materials Department, and Center for Academic Surgery, Queen Mary University of London, London E1 4NS. o.hakimi@ qmul.ac.uk
Biomacromolecules 7:2901-8. 2006..Observed separation of the microfibrils in fractured brins suggests that the multifibrillar structure of the silk fiber contributes to toughness by allowing dissipation of energy in the controlled propagation of cracks...
Beta transition and stress-induced phase separation in the spinning of spider dragline silkD P Knight
Department of Zoology, South Parks Road, OX1 3PS, Oxford, UK
Int J Biol Macromol 27:205-10. 2000..Measurements of draw stress at different draw rates during silking confirm that a stress-induced phase transition occurs...
Changes in element composition along the spinning duct in a Nephila spiderD P Knight
Zoology Department, University of Oxford, UK
Naturwissenschaften 88:179-82. 2001..Thus precise control of the ionic environment within the spider's spinning duct may be important in forming a tough insoluble thread and when devising mimetic processes to spin silk proteins industrially...
Biological liquid crystal elastomersDavid P Knight
Zoology Department, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
Philos Trans R Soc Lond B Biol Sci 357:155-63. 2002..In this paper, the possibility that other transversely banded fibrillar proteins are also LCEs is discussed...
Spinning an elastic ribbon of spider silkDavid P Knight
Department of Zoology, University of Oxford, UK
Philos Trans R Soc Lond B Biol Sci 357:219-27. 2002..This is achieved by the combination of an initial internal draw down, well inside the duct, and a final draw down, after the silk has left the spigot. The spinning mechanism in Loxosceles may be more ancestral...
Liquid crystalline spinning of spider silkF Vollrath
Zoology Department, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
Nature 410:541-8. 2001....
Comparison of the spinning of selachian egg case ply sheets and orb web spider dragline filamentsD P Knight
Department of Zoology, Oxford University, South Parks Road, Oxford OX1 3PS, UK
Biomacromolecules 2:323-34. 2001..The most important difference is that spiders produce a tough material by unfolding and hydrogen-bonding their silk dope molecules while Selachian fish do it by covalently cross-linking the molecules without unfolding them...
Mapping domain structures in silks from insects and spiders related to protein assemblyElisabetta Bini
Department of Biomedical Engineering and Bioengineering Center, Tufts University, 4 Colby Street, Medford, MA 02155, USA
J Mol Biol 335:27-40. 2004..Thus these insights have implications for structural biology and relevance to fundamental and applied questions in material science and engineering...
Conformation transition in silk protein films monitored by time-resolved Fourier transform infrared spectroscopy: effect of potassium ions on Nephila spidroin filmsXin Chen
Department of Macromolecular Science, The Key Laboratory of Molecular Engineering of Polymers of Education Ministry, Fudan University, Shanghai 200433, People s Republic of China
Biochemistry 41:14944-50. 2002..We discuss the possible significance of these findings to an understanding of the way that spiders spin silk...
Rheological characterization of nephila spidroin solutionXin Chen
Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
Biomacromolecules 3:644-8. 2002....
Spider silk proteins--mechanical property and gene sequenceAnna Rising
Department of Pathology, Swedish University of Agricultural Sciences BioMedical Centre, Uppsala, Sweden
Zoolog Sci 22:273-81. 2005..This review aims to link recent molecular data, often translated into amino acid sequences and predicted three dimensional structural motifs, to known mechanical properties...
Synthesis and characterization of multiblock copolymers based on spider dragline silk proteinsChuncai Zhou
The Key Laboratory of Molecular Engineering of Polymers and Department of Macromolecular Science, Fudan University, Shanghai 200433, P. R. China
Biomacromolecules 7:2415-9. 2006..These multiblock polymers showed a significant solubility in the component solvents. Moreover, the copolymer which contains the short polyisoprene segment would aggregate into a micellar-like structure, as observed by TEM...
Effect of metallic ions on silk formation in the Mulberry silkworm, Bombyx moriLi Zhou
The Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, National Microanalysis Center, Fudan University, Shanghai, 200433, People's Republic of China
J Phys Chem B 109:16937-45. 2005....
Further investigation on potassium-induced conformation transition of Nephila spidroin film with two-dimensional infrared correlation spectroscopyXianneng Peng
Department of Macromolecular Science, The Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai, 200433, People's Republic of China
Biomacromolecules 6:302-8. 2005..We present a single coherent and detailed hypothesis for the assembly and secondary structural transition of silk proteins in vivo and in vitro based on our findings and on evidence from other laboratories...
Copper in the silk formation process of Bombyx mori silkwormLi Zhou
Department of Macromolecular Science, The Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai 200433, PR China
FEBS Lett 554:337-41. 2003..Taken together these findings indicate that copper could play a role in the natural spinning process in silkworms...
Conformation transition kinetics of Bombyx mori silk proteinXin Chen
The Key Laboratory of Molecular Engineering of Polymers of MOE, Department of Macromolecular Science, Fudan University, Shanghai 200433, People s Republic of China
Proteins 68:223-31. 2007....
