Genomes and Genes
Peter J Kilshaw
Affiliation: Institute for Animal Health
- Alpha E: no more rejection?Peter J Kilshaw
The Babraham Institute, Cambridge, CB2 4AT, United Kingdom
J Exp Med 196:873-5. 2002
- A novel type of deubiquitinating enzymePaul C Evans
Molecular Immunology Programme, The Babraham Institute, Cambridge CB2 4AT, United Kingdom
J Biol Chem 278:23180-6. 2003..We also provide evidence for an additional ubiquitin binding site in the C-terminal part of the molecule. Our data provide the first demonstration of functional activity among OTU proteins...
- Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activityPaul C Evans
Molecular Immunology Programme, The Babraham Institute, Cambridge CB2 4AT, UK
Biochem J 378:727-34. 2004..A20 did not have a global effect on ubiquitinated cellular proteins, which indicates that its activity is target-specific. The biological significance of the catalytic domain is unknown...
- Role of the alphaI domain in ligand binding by integrin alphaEbeta7Elaine M Corps
Molecular Immunology Programme, The Babraham Institute, Babraham, Cambridge, GB
Eur J Immunol 33:2599-608. 2003..Nevertheless, for alphaE, the fully open conformation may represent an extreme situation that does not occur physiologically...