Research Topics
Genomes and GenesSpecies | R A HubnerSummaryAffiliation: Institute of Cancer Research Country: UK Publications
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Detail Information
Publications
Molecular advances in medullary thyroid cancer diagnosticsRichard A Hubner
Institute of Cancer Research, Cancer Genetics, 15 Cotswold Road, Sutton, SM2 5NG, United Kingdom
Clin Chim Acta 370:2-8. 2006..Mutation analysis of RET in individuals with MEN2 has identified a number of different mutations, and correlation with cancer biology and clinical outcome has led to tailoring of management according to the mutation detected...
Ornithine decarboxylase G316A genotype is prognostic for colorectal adenoma recurrence and predicts efficacy of aspirin chemopreventionRichard A Hubner
Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom
Clin Cancer Res 14:2303-9. 2008..We investigated the influence of ODC G316A on the chemopreventive activity of aspirin in colorectal adenoma (CRA) recurrence...
Thymidylate synthase polymorphisms, folate and B-vitamin intake, and risk of colorectal adenomaR A Hubner
Section of Cancer Genetics, Institute of Cancer Research, 15 Cotswold Road, Sutton SM2 5NG, UK
Br J Cancer 97:1449-56. 2007....
Polymorphisms in PTGS1, PTGS2 and IL-10 do not influence colorectal adenoma recurrence in the context of a randomized aspirin intervention trialRichard A Hubner
Section of Cancer Genetics, Institute of Cancer Research, Sutton SM2 5NG, United Kingdom
Int J Cancer 121:2001-4. 2007..These data indicate that these polymorphisms are unlikely to influence CRA recurrence and cannot be used to identify individuals who derive benefit from aspirin intervention...
Should folic acid fortification be mandatory? NoRichard A Hubner
Institute of Cancer Research, Section of Cancer Genetics, Sutton SM2 5NG
BMJ 334:1253. 2007
MTHFR C677T has differential influence on risk of MSI and MSS colorectal cancerRichard A Hubner
Section of Cancer Genetics, Institute of Cancer Rsearch, 15 Cotswold Road, Sutton, Surrey SM2 5NG, UK
Hum Mol Genet 16:1072-7. 2007..Stratification by MSI status should aid future studies investigating the complex relationships between genotype, environmental factors and CRC risk...
MTHFR C677T and colorectal cancer risk: A meta-analysis of 25 populationsRichard A Hubner
Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey, United Kingdom
Int J Cancer 120:1027-35. 2007....
Folate metabolism polymorphisms influence risk of colorectal adenoma recurrenceRichard A Hubner
Institute of Cancer Research, Section of Cancer Genetics, 15 Cotswold Road, Sutton SM2 5NG, United Kingdom
Cancer Epidemiol Biomarkers Prev 15:1607-13. 2006..These findings provide additional support for the hypothesis that germ line variants in folate metabolism genes influence the development of colorectal adenomas...
Dairy products, polymorphisms in the vitamin D receptor gene and colorectal adenoma recurrenceRichard A Hubner
Institute of Cancer Research, Section of Cancer Genetics, Sutton SM2 5NG, United Kingdom
Int J Cancer 123:586-93. 2008..02). These findings indicate dairy products, and in particular milk, have chemopreventive activity against CRA recurrence...
Genetic variants of UGT1A6 influence risk of colorectal adenoma recurrenceRichard A Hubner
Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom and Division of Epidemiology and Public Health, Medical School, Queen s Medical Centre, University of Nottingham, Nottingham, United Kingdom
Clin Cancer Res 12:6585-9. 2006..We aimed to further investigate the effect of these genetic variants on the development of colorectal neoplasia...
Re: MLH1 93G>A promoter polymorphism and the risk of microsatellite-unstable colorectal cancerRichard A Hubner
J Natl Cancer Inst 99:1490; author reply 1490-1. 2007
