A Patrick Gunning

Summary

Affiliation: Institute for Animal Health
Country: UK

Publications

  1. ncbi Comparative imaging of a bacterial surface-located GFP fusion protein by epifluorescence and scanning near-field optical microscopy
    A P Gunning
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, U K
    J Microsc 218:46-51. 2005
  2. ncbi Watching molecular processes with the atomic force microscope: dynamics of polymer adsorption and desorption at the single molecule level
    A P Gunning
    Institute of Food Research, Norwich Research Park, Colney, Norwich, UK
    J Microsc 216:52-6. 2004
  3. ncbi Mapping specific adhesive interactions on living human intestinal epithelial cells with atomic force microscopy
    A Patrick Gunning
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
    FASEB J 22:2331-9. 2008
  4. ncbi Atomic force microscopy of emulsion droplets: probing droplet-droplet interactions
    A P Gunning
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, United Kingdom
    Langmuir 20:116-22. 2004
  5. ncbi Recognition of galactan components of pectin by galectin-3
    A Patrick Gunning
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
    FASEB J 23:415-24. 2009
  6. ncbi Effect of surfactant type on surfactant--protein interactions at the air-water interface
    Paul A Gunning
    Institute of Food Research, Norwich Laboratory, Norwich Research Park, Colney NR4 7UA, United Kingdom
    Biomacromolecules 5:984-91. 2004
  7. ncbi Probing the in situ competitive displacement of protein by nonionic surfactant using atomic force microscopy
    Nicola C Woodward
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
    Langmuir 26:12560-6. 2010
  8. ncbi Interfacial characterization of beta-lactoglobulin networks: displacement by bile salts
    Julia Maldonado-Valderrama
    Institute of Food Research, Norwich Research Park, NR4 7UA, Norwich, UK
    Langmuir 24:6759-67. 2008
  9. ncbi Adsorption of bile salts and pancreatic colipase and lipase onto digalactosyldiacylglycerol and dipalmitoylphosphatidylcholine monolayers
    Boon Seang Chu
    Institute of Food Research, Norwich Research Park, Colney Lane, Norwich NR4 7UA, UK
    Langmuir 26:9782-93. 2010
  10. ncbi Comparison of the orogenic displacement of sodium caseinate with the caseins from the air-water interface by nonionic surfactants
    N C Woodward
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, U K
    Langmuir 25:6739-44. 2009

Collaborators

Detail Information

Publications21

  1. ncbi Comparative imaging of a bacterial surface-located GFP fusion protein by epifluorescence and scanning near-field optical microscopy
    A P Gunning
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, U K
    J Microsc 218:46-51. 2005
    ..Furthermore, and for the first time, the inherent advantages in resolution of the near-field images provides highly specific details of the location of a GFP fusion protein on a bacterial cell surface...
  2. ncbi Watching molecular processes with the atomic force microscope: dynamics of polymer adsorption and desorption at the single molecule level
    A P Gunning
    Institute of Food Research, Norwich Research Park, Colney, Norwich, UK
    J Microsc 216:52-6. 2004
    ..In addition, these AFM studies have provided new mechanistic clues to the adsorption/desorption process of this polysaccharide...
  3. ncbi Mapping specific adhesive interactions on living human intestinal epithelial cells with atomic force microscopy
    A Patrick Gunning
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
    FASEB J 22:2331-9. 2008
    ..Adhesive events were used to map the location of binding sites on the cell surface revealing heterogeneity in their distribution within and between cells within the monolayer...
  4. ncbi Atomic force microscopy of emulsion droplets: probing droplet-droplet interactions
    A P Gunning
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, United Kingdom
    Langmuir 20:116-22. 2004
    ..Careful experimental studies suggest that these structures may be imaging artifacts and are not perturbations of the droplet surface determined by the composition of the interface...
  5. ncbi Recognition of galactan components of pectin by galectin-3
    A Patrick Gunning
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
    FASEB J 23:415-24. 2009
    ..Present studies suggest that bioactivity resides in the neutral sugar side chains of pectin polysaccharides and that these components could be isolated and modified to optimize bioactivity...
  6. ncbi Effect of surfactant type on surfactant--protein interactions at the air-water interface
    Paul A Gunning
    Institute of Food Research, Norwich Laboratory, Norwich Research Park, Colney NR4 7UA, United Kingdom
    Biomacromolecules 5:984-91. 2004
    ..This has been attributed to surfactant-protein binding that initially strengthens the protein network at low surfactant concentrations. Evidence obtained from surface shear rheology supports this assertion...
  7. ncbi Probing the in situ competitive displacement of protein by nonionic surfactant using atomic force microscopy
    Nicola C Woodward
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
    Langmuir 26:12560-6. 2010
    ..These data have been compared to those obtained using the more traditional techniques of dilatational rheology, surface loading, and surface potential measurements for analogous beta-lactoglobulin-stabilized droplets or emulsions...
  8. ncbi Interfacial characterization of beta-lactoglobulin networks: displacement by bile salts
    Julia Maldonado-Valderrama
    Institute of Food Research, Norwich Research Park, NR4 7UA, Norwich, UK
    Langmuir 24:6759-67. 2008
    ..This in turn affects the strength of the protein network and the ability to resist displacement by surfactants...
  9. ncbi Adsorption of bile salts and pancreatic colipase and lipase onto digalactosyldiacylglycerol and dipalmitoylphosphatidylcholine monolayers
    Boon Seang Chu
    Institute of Food Research, Norwich Research Park, Colney Lane, Norwich NR4 7UA, UK
    Langmuir 26:9782-93. 2010
    ....
  10. ncbi Comparison of the orogenic displacement of sodium caseinate with the caseins from the air-water interface by nonionic surfactants
    N C Woodward
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, U K
    Langmuir 25:6739-44. 2009
    ....
  11. ncbi Visualization of plant cell walls by atomic force microscopy
    A R Kirby
    Institute of Food Research, Norwich Laboratory, Norwich Research Park, Colney, England
    Biophys J 70:1138-43. 1996
    ..The three-dimensional images obtained highlighted the layered structure of the plant cell walls and revealed features interpreted as individual cellulose microfibrils and plasmodesmata...
  12. ncbi Allergens of the cupin superfamily
    E N Mills
    Institute of Food Research, Norwich Research Park, Colney, UK
    Biochem Soc Trans 30:925-9. 2002
    ....
  13. ncbi In situ measurement of the displacement of protein films from the air/water interface by surfactant
    A R Mackie
    Institute of Food Research, Norwich Research Park, Colney, NR4 7UA, United Kingdom
    Biomacromolecules 2:1001-6. 2001
    ..This indicates that at least in the early stages of displacement, the mixed film was dominated by the behavior of the protein in the film...
  14. ncbi Formation of thermally induced aggregates of the soya globulin beta-conglycinin
    E N Mills
    Institute of Food Research, Norwich Research Park, Colney, NR4 7UA, Norwich, UK
    Biochim Biophys Acta 1547:339-50. 2001
    ..The ability of beta-conglycinin to form such distinctive aggregates is discussed in relation to the presence of acidic inserts in certain of the beta-conglycinin subunits, which may play an important role in limiting aggregate length...
  15. ncbi Controlled release of protein from viable Lactococcus lactis cells
    Régis Stentz
    Integrated Biology of the Gastrointestinal Tract, Norwich Research Park, Norwich, United Kingdom
    Appl Environ Microbiol 76:3026-31. 2010
    ..Taken together, these results demonstrate the potential of this novel approach for applications including product recovery in industrial fermentations, food processing, and medical therapy...
  16. ncbi Effect of processing on the displacement of whey proteins: applying the orogenic model to a real system
    Nicola C Woodward
    Institute of Food Research, Norwich Research Park, Norwich, NR4 7UA United Kingdom
    J Agric Food Chem 52:1287-92. 2004
    ..Despite the lower surface activity of Tween 60, WPI was still observed to be present at the interface at surface pressure values greater than those by which beta-lactoglobulin had been completely displaced...
  17. ncbi Taking multicalixarenes into the nanoworld: first third-generation calixarene dendrimer
    Ruth Lalor
    School of Pharmacy, University of East Anglia, Norwich, UK
    Chem Commun (Camb) 46:8665-7. 2010
    ..We report the first synthesis of a dendritic multicalixarene, featuring twenty-one calixarene units, which when adsorbed onto mica, forms regular assemblies which can then further aggregate to form larger clusters...
  18. ncbi Detection of transglucosidase-catalyzed polysaccharide synthesis on a surface in real time using surface plasmon resonance spectroscopy
    Carla Clé
    Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, United Kingdom
    J Am Chem Soc 130:15234-5. 2008
    ..This surface method will have utility in a wide range of carbohydrate enzyme systems including screens...
  19. ncbi Both binding sites of the starch-binding domain of Aspergillus niger glucoamylase are essential for inducing a conformational change in amylose
    T Giardina
    Nutrition, Health and Consumer Science Division, Institute of Food Research, Colney, Norwich, UK
    J Mol Biol 313:1149-59. 2001
    ..The binding of parallel amylosic chains to the SBD may provide a basis for understanding the role of the SBD in facilitating enzymatic degradation of crystalline starches by glucoamylase 1...
  20. ncbi Lipid dynamics in the plasma membrane of ram and bull spermatozoa after washing and exposure to macromolecules BSA and PVP
    C A Wolfe
    Department of Food Biophysics, Institute of Food Research, Norwich, Norfolk, United Kingdom
    Mol Reprod Dev 59:306-13. 2001
    ..It is concluded that diffusion of lipids in the plasma membrane of ejaculated ram and bull spermatozoa is influenced by seminal plasma proteins and the composition of the suspending medium. Mol. Reprod. Dev. 59:306-313, 2001...
  21. ncbi Interfacial structure of sugar beet pectin studied by atomic force microscopy
    A Gromer
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
    Langmuir 25:8012-8. 2009
    ..Such knowledge might be used to modify rationally the pectin in order to improve its emulsifying properties, leading to broader commercial applications...