Janine T Erler

Summary

Affiliation: Institute of Cancer Research
Country: UK

Publications

  1. ncbi The role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancer
    Ann Marie Baker
    Section of Cell and Molecular Biology, The Institute of Cancer Research, London, UK
    J Natl Cancer Inst 103:407-24. 2011
  2. ncbi Three-dimensional context regulation of metastasis
    Janine T Erler
    Hypoxia and Metastasis Team, Section of Cell and Molecular Biology, The Institute of Cancer Research, London, UK
    Clin Exp Metastasis 26:35-49. 2009
  3. ncbi The rationale for targeting the LOX family in cancer
    Holly E Barker
    Hypoxia and Metastasis Team, The Institute of Cancer Research, London SW3 6JB, UK
    Nat Rev Cancer 12:540-52. 2012
  4. ncbi LOXL2-mediated matrix remodeling in metastasis and mammary gland involution
    Holly E Barker
    Section of Cell and Molecular Biology, The Institute of Cancer Research, London, United Kingdom
    Cancer Res 71:1561-72. 2011
  5. ncbi Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer
    Thomas R Cox
    Cancer Research UK Tumour Cell Signalling Unit, Section of Cell and Molecular Biology, The Institute of Cancer Research, London, UK
    Dis Model Mech 4:165-78. 2011

Collaborators

Detail Information

Publications5

  1. ncbi The role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancer
    Ann Marie Baker
    Section of Cell and Molecular Biology, The Institute of Cancer Research, London, UK
    J Natl Cancer Inst 103:407-24. 2011
    ..Emerging evidence implicates lysyl oxidase (LOX), an extracellular matrix-modifying enzyme, in promoting metastasis of solid tumors. We investigated whether LOX plays an important role in the metastasis of colorectal cancer (CRC)...
  2. ncbi Three-dimensional context regulation of metastasis
    Janine T Erler
    Hypoxia and Metastasis Team, Section of Cell and Molecular Biology, The Institute of Cancer Research, London, UK
    Clin Exp Metastasis 26:35-49. 2009
    ..Thus, clarifying the molecular pathways by which ECM remodeling and tumor hypoxia intersect to promote tumor progression should identify novel therapeutic targets...
  3. ncbi The rationale for targeting the LOX family in cancer
    Holly E Barker
    Hypoxia and Metastasis Team, The Institute of Cancer Research, London SW3 6JB, UK
    Nat Rev Cancer 12:540-52. 2012
    ..We also discuss how targeting this family of proteins might lead to a new avenue of cancer therapeutics...
  4. ncbi LOXL2-mediated matrix remodeling in metastasis and mammary gland involution
    Holly E Barker
    Section of Cell and Molecular Biology, The Institute of Cancer Research, London, United Kingdom
    Cancer Res 71:1561-72. 2011
    ..Our findings highlight the importance of LOXL2 in breast cancer progression and support the development of anti-LOXL2 therapeutics for the treatment of metastatic breast cancer...
  5. ncbi Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer
    Thomas R Cox
    Cancer Research UK Tumour Cell Signalling Unit, Section of Cell and Molecular Biology, The Institute of Cancer Research, London, UK
    Dis Model Mech 4:165-78. 2011
    ..This can only be achieved through the use of appropriate in vitro and in vivo models to mimic disease, and with technologies that enable accurate monitoring, imaging and quantification of the ECM...