Paolo Vineis

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. doi request reprint Global cancer patterns: causes and prevention
    Paolo Vineis
    MRC PHE Centre for Environment and Health, School of Public Health, Imperial College, London HuGeF Foundation, Torino, Italy Electronic address
    Lancet 383:549-57. 2014
  2. doi request reprint Advancing the application of omics-based biomarkers in environmental epidemiology
    Paolo Vineis
    MRC HPA Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
    Environ Mol Mutagen 54:461-7. 2013
  3. pmc Adiposity, hormone replacement therapy use and breast cancer risk by age and hormone receptor status: a large prospective cohort study
    Rebecca Ritte
    Division of Cancer Epidemiology, German Cancer Research Center DKFZ, Im Neuenheimer Feld TP4, Heidelberg, 69120, Germany
    Breast Cancer Res 14:R76. 2012
  4. pmc Compliance with clinical practice guidelines for breast cancer treatment: a population-based study of quality-of-care indicators in Italy
    Carlotta Sacerdote
    Cancer Epidemiology Unit, San Giovanni Battista Hospital, CPO Piemonte and University of Turin, Turin, Italy
    BMC Health Serv Res 13:28. 2013
  5. pmc Human endogenous retroviruses and cancer prevention: evidence and prospects
    Luca Cegolon
    Department of Molecular Medicine, Padua University, Padua, Italy
    BMC Cancer 13:4. 2013
  6. doi request reprint Climate change impacts on water salinity and health
    Paolo Vineis
    MRC HPA Centre for Environment and Health, School of Public Health, Imperial College London, UK
    J Epidemiol Glob Health 1:5-10. 2011
  7. pmc Causal diagrams in systems epidemiology
    Michael Joffe
    Department of Epidemiology and Biostatistics, Imperial College London, London, UK
    Emerg Themes Epidemiol 9:1. 2012
  8. pmc The mediterranean dietary pattern and breast cancer risk in Greek-Cypriot women: a case-control study
    Christiana A Demetriou
    Department of EM Molecular Pathology, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus
    BMC Cancer 12:113. 2012
  9. pmc Environment and cancer: the legacy of Lorenzo Tomatis
    Rodolfo Saracci
    IFC National Research Council, Via Trieste 41, 56126 Pisa, Italy
    Environ Health 10:S1. 2011
  10. pmc Assessing causal relationships in genomics: From Bradford-Hill criteria to complex gene-environment interactions and directed acyclic graphs
    Sara Geneletti
    Department of Statistics, London School of Economics, Houghton Street, London, UK
    Emerg Themes Epidemiol 8:5. 2011

Collaborators

Detail Information

Publications154 found, 100 shown here

  1. doi request reprint Global cancer patterns: causes and prevention
    Paolo Vineis
    MRC PHE Centre for Environment and Health, School of Public Health, Imperial College, London HuGeF Foundation, Torino, Italy Electronic address
    Lancet 383:549-57. 2014
    ..Primary prevention must therefore be prioritised as an integral part of global cancer control...
  2. doi request reprint Advancing the application of omics-based biomarkers in environmental epidemiology
    Paolo Vineis
    MRC HPA Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
    Environ Mol Mutagen 54:461-7. 2013
    ....
  3. pmc Adiposity, hormone replacement therapy use and breast cancer risk by age and hormone receptor status: a large prospective cohort study
    Rebecca Ritte
    Division of Cancer Epidemiology, German Cancer Research Center DKFZ, Im Neuenheimer Feld TP4, Heidelberg, 69120, Germany
    Breast Cancer Res 14:R76. 2012
    ....
  4. pmc Compliance with clinical practice guidelines for breast cancer treatment: a population-based study of quality-of-care indicators in Italy
    Carlotta Sacerdote
    Cancer Epidemiology Unit, San Giovanni Battista Hospital, CPO Piemonte and University of Turin, Turin, Italy
    BMC Health Serv Res 13:28. 2013
    ..The aim of this population-based study was to evaluate the impact of regional guidelines (Piedmont guidelines, PGL) for breast cancer diagnosis and treatment on quality-of-care indicators in the Northwestern Italian region of Piedmont...
  5. pmc Human endogenous retroviruses and cancer prevention: evidence and prospects
    Luca Cegolon
    Department of Molecular Medicine, Padua University, Padua, Italy
    BMC Cancer 13:4. 2013
    ....
  6. doi request reprint Climate change impacts on water salinity and health
    Paolo Vineis
    MRC HPA Centre for Environment and Health, School of Public Health, Imperial College London, UK
    J Epidemiol Glob Health 1:5-10. 2011
    ....
  7. pmc Causal diagrams in systems epidemiology
    Michael Joffe
    Department of Epidemiology and Biostatistics, Imperial College London, London, UK
    Emerg Themes Epidemiol 9:1. 2012
    ....
  8. pmc The mediterranean dietary pattern and breast cancer risk in Greek-Cypriot women: a case-control study
    Christiana A Demetriou
    Department of EM Molecular Pathology, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus
    BMC Cancer 12:113. 2012
    ..Diet has long been suspected to impact on breast cancer risk. In this study we evaluated whether the degree of adherence to a Mediterranean diet pattern modifies breast cancer risk amongst Greek-Cypriot women...
  9. pmc Environment and cancer: the legacy of Lorenzo Tomatis
    Rodolfo Saracci
    IFC National Research Council, Via Trieste 41, 56126 Pisa, Italy
    Environ Health 10:S1. 2011
    ....
  10. pmc Assessing causal relationships in genomics: From Bradford-Hill criteria to complex gene-environment interactions and directed acyclic graphs
    Sara Geneletti
    Department of Statistics, London School of Economics, Houghton Street, London, UK
    Emerg Themes Epidemiol 8:5. 2011
    ..e., research that integrates knowledge, data, methods, techniques, and reasoning from multiple disciplines, approaches and levels of analysis to generate knowledge that no discipline alone may achieve...
  11. pmc The association of education with body mass index and waist circumference in the EPIC-PANACEA study
    Silke Hermann
    Division of Cancer Epidemiology, German Cancer Research Centre, Heidelberg, Germany
    BMC Public Health 11:169. 2011
    ..To examine the association of education with body mass index (BMI) and waist circumference (WC) in the European Prospective Investigation into Cancer and Nutrition (EPIC)...
  12. pmc Significance testing in ridge regression for genetic data
    Erika Cule
    Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK
    BMC Bioinformatics 12:372. 2011
    ..It is therefore desirable to obtain an estimate of the significance of each ridge regression coefficient...
  13. doi request reprint The emerging epidemic of environmental cancers in developing countries
    P Vineis
    Department of Epidemiology and Public Health, Imperial College of Science, Technology and Medicine, London, UK
    Ann Oncol 20:205-12. 2009
    ..A systematic review was not possible given the sparse nature of the data, but we suggest that the burden of environmental exposures to carcinogens can be substantial in developing countries...
  14. ncbi request reprint The population dynamics of cancer: a Darwinian perspective
    Paolo Vineis
    Department of Epidemiology and Public Health, Imperial College London, St Mary s Campus, Norfolk Place, W2 1PG, London, UK
    Int J Epidemiol 35:1151-9. 2006
    ....
  15. ncbi request reprint Exposure to solvents and risk of non-Hodgkin lymphoma: clues on putative mechanisms
    Paolo Vineis
    University of Turin, Turin, Italy
    Cancer Epidemiol Biomarkers Prev 16:381-4. 2007
    ..Both hypotheses (i.e., the interaction with autoimmune diseases and with familial predisposition) indirectly suggest that an immunologic mechanism could be involved in lymphomagenesis from solvents...
  16. pmc Causal models in epidemiology: past inheritance and genetic future
    Paolo Vineis
    Division of Epidemiology, Public Health and Primary Care, Imperial College London, Faculty of Medicine, Imperial College London, St Mary s Campus, Norfolk Place, London, W2 1PG, UK
    Environ Health 5:21. 2006
    ..4. At the population level, there is additional uncertainty in quantifying interaction and assigning etiologic fractions to different necessary causes because of ignorance about the components of the sufficient cause...
  17. ncbi request reprint Air pollution and risk of lung cancer in a prospective study in Europe
    Paolo Vineis
    Imperial College London, London, UK
    Int J Cancer 119:169-74. 2006
    ..The association with NO(2) did not change after adjustment by cotinine and additional potential confounders, including occupational exposures. No clear association was found with other pollutants...
  18. pmc Models of carcinogenesis: an overview
    Paolo Vineis
    Department of Epidemiology and Public Health, MRC HPA Centre for Environment and Health, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, UK
    Carcinogenesis 31:1703-9. 2010
    ..Our description, though simplified, looks realistic, it is able to capture the historical sequence of carcinogenesis theories in the last century and can serve as a frame to make research hypotheses more explicit...
  19. ncbi request reprint Air pollution and cancer: biomarker studies in human populations
    Paolo Vineis
    Department of Epidemiology and Public Health, Imperial College of Science, Technology and Medicine, Norfolk Place, London, UK
    Carcinogenesis 26:1846-55. 2005
    ....
  20. pmc Genetic screening and occupational and environmental exposures
    P Vineis
    Imperial College London, UK
    Occup Environ Med 62:657-62, 597. 2005
  21. ncbi request reprint Misuse of genetic data in environmental epidemiology
    Paolo Vineis
    Department of Epidemiology and Public Health, Imperial College London, Norfolk Place W2 1PG, London, UK
    Ann N Y Acad Sci 1076:163-7. 2006
    ..Finally, I will describe a specific example of potential misuse of genetic information...
  22. ncbi request reprint The challenge of low levels of exposure
    Paolo Vineis
    Environmental Epidemiology, Department of Epidemiology and Public Health, Imperial College London, St Mary s Campus, Norfolk Place W2 1PG London, UK
    Prev Med 44:107-8. 2007
  23. doi request reprint Methodological insights: fuzzy sets in medicine
    P Vineis
    Imperial College London, Department of Epidemiology and Public Health, Norfolk Place, London W2 1PG, UK
    J Epidemiol Community Health 62:273-8. 2008
    ....
  24. pmc A Darwinian perspective: right premises, questionable conclusion. A commentary on Niall Shanks and Rebecca Pyles' "evolution and medicine: the long reach of "Dr. Darwin""
    Paolo Vineis
    Department of Epidemiology and Community Health, Imperial College London, St Mary s Campus, Norfolk Place, W2 1PG, London, UK
    Philos Ethics Humanit Med 3:6. 2008
    ..Epidemics of cancer could have been prevented if experimental data had been used to reduce human exposures or ban carcinogenic chemicals. We discuss examples...
  25. doi request reprint Integrating biomarkers into molecular epidemiological studies
    Paolo Vineis
    MRC HPA Centre for Environment and Health, School of Public Health, Imperial College London, London, UK
    Curr Opin Oncol 23:100-5. 2011
    ..Recent developments in both data acquisition techniques and laboratory approaches advocate for a more extensive and refined use of biomarkers...
  26. doi request reprint Expectations and challenges stemming from genome-wide association studies
    Paolo Vineis
    Department of Epidemiology and Public Health, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Mutagenesis 23:439-44. 2008
    ..The present Commentary is a report of an Environmental Cancer Risk, Nutrition and Individual Susceptibility network Workshop held in Venice in October 2007 and discusses some of the problems outlined above, with examples...
  27. ncbi request reprint Genetic susceptibility according to three metabolic pathways in cancers of the lung and bladder and in myeloid leukemias in nonsmokers
    P Vineis
    Imperial College London, London, UK
    Ann Oncol 18:1230-42. 2007
    ..We chose a set of candidate single nucleotide polymorphisms (SNPs) to investigate gene-environment interactions in three types of cancer that have been related to air pollution (lung, bladder and myeloid leukemia)...
  28. doi request reprint Anthropometric characteristics and non-Hodgkin's lymphoma and multiple myeloma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Julie A Britton
    Department of Epidemiology and Public Health, Imperial College London, Room 151, St Mary s Campus, Norfolk Place W2 1PG, London, UK
    Haematologica 93:1666-77. 2008
    ..It has been hypothesized that this may be due, in part, to the parallel rising prevalence of obesity. It is biologically plausible that anthropometric characteristics can infuence the risk of non-Hodgkin's lymphoma and multiple myeloma...
  29. doi request reprint Genome-wide association studies may be misinterpreted: genes versus heritability
    Paolo Vineis
    Molecular and Genetic Epidemiology Unit HuGeF, MRC HPA Centre for Environment and Health, School of Public Health, Imperial College, Norfolk Place, W2 1PG London, UK
    Carcinogenesis 32:1295-8. 2011
    ..Such estimates in turn cannot be used to estimate the proportion of cases that are due to environmental factors...
  30. ncbi request reprint Commentary: First steps in molecular epidemiology: Lower et al. 1979
    Paolo Vineis
    Imperial College London and University of Torino
    Int J Epidemiol 36:20-2. 2007
  31. pmc Lung cancers attributable to environmental tobacco smoke and air pollution in non-smokers in different European countries: a prospective study
    Paolo Vineis
    Imperial College London, London UK
    Environ Health 6:7. 2007
    ..It is therefore useful to estimate the burden of disease associated with indoor and outdoor air pollution...
  32. ncbi request reprint Scientific basis for the Precautionary Principle
    Paolo Vineis
    Imperial College London, St Mary s Campus, Norfolk Place, W2 1PG London, UK
    Toxicol Appl Pharmacol 207:658-62. 2005
    ....
  33. ncbi request reprint A self-fulfilling prophecy: are we underestimating the role of the environment in gene-environment interaction research?
    Paolo Vineis
    Department of Epidemiology and Public Health, Imperial College London, UK
    Int J Epidemiol 33:945-6. 2004
  34. pmc The impact of new research technologies on our understanding of environmental causes of disease: the concept of clinical vulnerability
    Paolo Vineis
    MRC HPA Centre for Environment and Health, Imperial College, UK
    Environ Health 8:54. 2009
    ..The development of "-omics", in spite of current limitations and lack of sound validation, could greatly contribute to the elucidation of the disease model we propose...
  35. pmc Environmental tobacco smoke and risk of respiratory cancer and chronic obstructive pulmonary disease in former smokers and never smokers in the EPIC prospective study
    P Vineis
    Imperial College, London W2 1PG
    BMJ 330:277. 2005
    ..To investigate the association between environmental tobacco smoke, plasma cotinine concentration, and respiratory cancer or death...
  36. ncbi request reprint Individual susceptibility to carcinogens
    Paolo Vineis
    Unit of Cancer Epidemiology, Dipartimento di Scienze Biomediche e Oncologia Umana, Torino, Italy
    Oncogene 23:6477-83. 2004
    ..Such susceptibility genes are of considerable scientific interest, but do not confer high enough risks to be clinically relevant...
  37. ncbi request reprint [New approaches to environmental epidemiology]
    Paolo Vineis
    Department of Epidemiology and Public Health, Imperial College, London, UK
    Epidemiol Prev 33:68-70. 2009
    ..In the mean time limitations of biomarkers need to be addressed, in particular the lack of validation, the limited reproducibility of several biomarkers, and the fact that measurements are expensive and cumbersome...
  38. doi request reprint Adherence to the World Cancer Research Fund/American Institute for Cancer Research guidelines and risk of death in Europe: results from the European Prospective Investigation into Nutrition and Cancer cohort study1,4
    Anne Claire Vergnaud
    Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
    Am J Clin Nutr 97:1107-20. 2013
    ....
  39. doi request reprint STrengthening the Reporting of OBservational studies in Epidemiology--Molecular Epidemiology (STROBE-ME): an extension of the STROBE statement
    Valentina Gallo
    Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK
    Mutagenesis 27:17-29. 2012
    ..The STROBE-ME recommendations are intended to complement the STROBE recommendations...
  40. doi request reprint STrengthening the Reporting of OBservational studies in Epidemiology - Molecular Epidemiology (STROBE-ME): an extension of the STROBE statement
    Valentina Gallo
    Department of Epidemiology and Biostatistics, Imperial College London, London, UK
    Eur J Clin Invest 42:1-16. 2012
    ..The STROBE-ME recommendations are intended to complement the STROBE recommendations...
  41. doi request reprint Fiber intake and total and cause-specific mortality in the European Prospective Investigation into Cancer and Nutrition cohort
    Shu Chun Chuang
    School of Public Health, Imperial College London, London, United Kingdom
    Am J Clin Nutr 96:164-74. 2012
    ..Previous studies have shown that high fiber intake is associated with lower mortality. However, little is known about the association of dietary fiber with specific causes of death other than cardiovascular disease (CVD)...
  42. doi request reprint Is concordance with World Cancer Research Fund/American Institute for Cancer Research guidelines for cancer prevention related to subsequent risk of cancer? Results from the EPIC study
    Dora Romaguera
    Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
    Am J Clin Nutr 96:150-63. 2012
    ....
  43. doi request reprint STrengthening the reporting of OBservational studies in Epidemiology-Molecular Epidemiology (STROBE-ME): an extension of the STROBE statement
    Valentina Gallo
    Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, St Mary s Campus Norfolk Place, W2 1PG London, UK
    Eur J Epidemiol 26:797-810. 2011
    ..The STROBE-ME recommendations are intended to complement the STROBE recommendations...
  44. ncbi request reprint Intake of fruits and vegetables and polymorphisms in DNA repair genes in bladder cancer
    Carlotta Sacerdote
    Unità di epidemiologia dei tumori, Dipartimento di Scienze Biomediche e Oncologia Umana, Università di Torino and CPO Piemonte, Torino, Italy
    Mutagenesis 22:281-5. 2007
    ..This study found a reduced risk associated with fruit and vegetable intake. No interaction was observed between fruit and vegetable consumption and DNA repair gene polymorphisms...
  45. doi request reprint ERCC1 haplotypes modify bladder cancer risk: a case-control study
    Fulvio Ricceri
    Unit of Epidemiology and Life Sciences, ISI Foundation, Turin, Italy
    DNA Repair (Amst) 9:191-200. 2010
    ..A detailed characterization of DNA repair genetic variation is warranted and might ultimately help to identify multiple susceptibility variants that could be responsible for joint effects on the risk...
  46. pmc Anthropometric measures, physical activity, and risk of glioma and meningioma in a large prospective cohort study
    Dominique S Michaud
    Department of Epidemiology and Public Health, Imperial College, London, UK
    Cancer Prev Res (Phila) 4:1385-92. 2011
    ..Results from this study support an increase in risk of meningioma with higher body fatness among both men and women. No association was observed between anthropometric measures and risk of glioma...
  47. ncbi request reprint CYP1A1, GSTM1 and GSTT1 polymorphisms and lung cancer: a pooled analysis of gene-gene interactions
    Paolo Vineis
    Imperial College London, London, UK
    Biomarkers 9:298-305. 2004
    ..7 (95% CI = 0.5-15.3). An association between lung cancer and the homozygous CYP1A1*2A genotype is confirmed. An apparent and biologically plausible interaction is suggested between this genotype and GSTM1...
  48. doi request reprint Second-hand smoke, cotinine levels, and risk of circulatory mortality in a large cohort study of never-smokers
    Valentina Gallo
    Division of Epidemiology, Public Health and Primary Care, Imperial College, London W2 1PG, United Kingdom
    Epidemiology 21:207-14. 2010
    ..A secondary aim was to use cotinine levels for cross-validating self-reported second-hand smoke exposure...
  49. pmc Dietary fibre intake and risks of cancers of the colon and rectum in the European prospective investigation into cancer and nutrition (EPIC)
    Neil Murphy
    Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
    PLoS ONE 7:e39361. 2012
    ..We explored whether the association remained after longer follow-up with a near threefold increase in colorectal cancer cases, and if the association varied by gender and tumour location...
  50. doi request reprint Biomarkers of ambient air pollution and lung cancer: a systematic review
    Christiana A Demetriou
    Department of Epidemiology and Biostatistics, Imperial College London, London, UK
    Occup Environ Med 69:619-27. 2012
    ..The identified biological markers have potential to shed light on the pathways of carcinogenesis, thus defining the association more clearly for public health interventions...
  51. doi request reprint STrengthening the Reporting of OBservational studies in Epidemiology: Molecular Epidemiology STROBE-ME. An extension of the STROBE statement
    Valentina Gallo
    Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK
    J Epidemiol Community Health 66:844-54. 2012
    ..The STROBE-ME recommendations are intended to complement the STROBE recommendations...
  52. doi request reprint Double-strand break DNA repair genotype predictive of later mortality and cancer incidence in a cohort of non-smokers
    David Neasham
    Division of Epidemiology, Public Health and Primary Care, Imperial College, UK
    DNA Repair (Amst) 8:60-71. 2009
    ..2.17-12.85). Observations from this prospective study suggest that polymorphisms of genes involved in the repair of DNA double-strand breaks significantly influence the risk of cancer and non-cancer disease, and can influence mortality...
  53. pmc A U-shaped relationship between plasma folate and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition
    Shu Chun Chuang
    School of Public Health, Imperial College London, London, UK
    Eur J Cancer 47:1808-16. 2011
    ..The positive association that we observed between methionine and pancreatic cancer may be sex dependent and may differ by time of follow-up. However, the mechanisms behind the observed associations warrant further investigation...
  54. doi request reprint Coffee and tea intake and risk of brain tumors in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study
    Dominique S Michaud
    Department of Epidemiology and Public Health, Imperial College, London, United Kingdom
    Am J Clin Nutr 92:1145-50. 2010
    ..In a recent US cohort study, total coffee and tea consumption was inversely associated with risk of glioma, and experimental studies showed that caffeine can slow the invasive growth of glioblastoma...
  55. doi request reprint STrengthening the Reporting of OBservational studies in Epidemiology--Molecular Epidemiology STROBE-ME: an extension of the STROBE statement
    Valentina Gallo
    Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK
    J Clin Epidemiol 64:1350-63. 2011
    ..The STROBE-ME recommendations are intended to complement the STROBE recommendations...
  56. doi request reprint STrengthening the Reporting of OBservational studies in Epidemiology - Molecular Epidemiology (STROBE-ME): an extension of the STROBE statement
    Valentina Gallo
    Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK
    Prev Med 53:377-87. 2011
    ..The STROBE-ME recommendations are intended to complement the STROBE recommendations...
  57. doi request reprint Meeting-in-the-middle using metabolic profiling - a strategy for the identification of intermediate biomarkers in cohort studies
    Marc Chadeau-Hyam
    Department of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, UK
    Biomarkers 16:83-8. 2011
    ..Predictive disease risk biomarkers that can be linked to exposure have proved difficult to identify in case-control studies...
  58. doi request reprint Plasma cotinine levels and pancreatic cancer in the EPIC cohort study
    Max Leenders
    School of Public Health, Imperial College London, London, UK
    Int J Cancer 131:997-1002. 2012
    ..People who smoke more than 30 cigarettes per day showed the highest risk compared to never smokers (OR: 4.15, 95% CI: 1.02-16.42). This study is the first to show that plasma cotinine levels are strongly related to pancreatic cancer...
  59. doi request reprint Association between total number of deaths, diabetes mellitus, incident cancers, and haplotypes in chromosomal region 8q24 in a prospective study
    Simonetta Guarrera
    Department of Genetics, Biology and Biochemistry, Universityof Torino, Torino, Italy
    Am J Epidemiol 175:479-87. 2012
    ..This observation can shed light on the mechanisms underlying reported associations between 8q24 variants and disparate chronic diseases...
  60. doi request reprint Meat consumption and prospective weight change in participants of the EPIC-PANACEA study
    Anne Claire Vergnaud
    Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
    Am J Clin Nutr 92:398-407. 2010
    ..Meat intake may be related to weight gain because of its high energy and fat content. Some observational studies have shown that meat consumption is positively associated with weight gain, but intervention studies have shown mixed results...
  61. doi request reprint Exposure to environmental tobacco smoke in childhood and incidence of cancer in adulthood in never smokers in the European Prospective Investigation into Cancer and Nutrition
    Shu Chun Chuang
    School of Public Health, Imperial College London, St Mary s Campus, Norfolk Place, W2 1PG, London, UK
    Cancer Causes Control 22:487-94. 2011
    ..among those who had been exposed daily in childhood (overall HR = 2.09, 95% CI = 1.14-3.84). In conclusion, childhood ETS exposure might not be a major risk factor for common cancers in adulthood...
  62. ncbi request reprint Expression of DNA repair and metabolic genes in response to a flavonoid-rich diet
    Simonetta Guarrera
    Institute for Scientific Interchange Foundation, Section of Life Sciences, Viale Settimio Severo 65, Torino, Italy
    Br J Nutr 98:525-33. 2007
    ..Larger studies are needed to clarify the possible effects of flavonoids in vivo; our preliminary results could help to better plan new studies on gene expression and diet...
  63. doi request reprint DNA methylation as a long-term biomarker of exposure to tobacco smoke
    Natalie S Shenker
    Department of Surgery and Cancer, Epigenetics Unit, Imperial College London, London, United Kingdom
    Epidemiology 24:712-6. 2013
    ..Most biomarkers of exposure tend to have short half-lives. This includes cotinine, a metabolite of nicotine widely used to assess smoke exposure. Cotinine is thus unsuitable as a determinant of past exposure to cigarette smoke...
  64. pmc Polymorphisms in the XRCC1 gene modify survival of bladder cancer patients treated with chemotherapy
    Carlotta Sacerdote
    HuGeF Human Genetics Foundation, Torino, Italy
    Int J Cancer 133:2004-9. 2013
    ..This finding may have clinical implications for the choice of therapy. ..
  65. doi request reprint The intake of grain fibers modulates cytokine levels in blood
    Shu Chun Chuang
    Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, UK
    Biomarkers 16:504-10. 2011
    ..5% of variance. Our study suggests that fiber intake, especially cereal fiber, may be associated with a decreased level of pro-inflammatory cytokines...
  66. doi request reprint Mediterranean dietary patterns and prospective weight change in participants of the EPIC-PANACEA project
    Dora Romaguera
    Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom
    Am J Clin Nutr 92:912-21. 2010
    ..There is an association between a greater adherence to a Mediterranean diet and a reduced risk of developing chronic diseases. However, it is not clear whether this dietary pattern may be protective also against the development of obesity...
  67. doi request reprint A field synopsis on low-penetrance variants in DNA repair genes and cancer susceptibility
    Paolo Vineis
    Department of Epidemiology and Public Health, Imperial College, London, UK
    J Natl Cancer Inst 101:24-36. 2009
    ..Although efforts have been made to create synopses for specific fields that summarize the data from genetic association studies, such an overview is not available for genes involved in DNA repair...
  68. doi request reprint Diabetes and the risk of non-Hodgkin's lymphoma and multiple myeloma in the European Prospective Investigation into Cancer and Nutrition
    Aneire E Khan
    Department of Epidemiology and Public Health, Division of Epidemiology, Public Health and Primary Care, Imperial College London, St Mary s Campus, Variety Wing, Norfolk Place, Paddington, London W2 1PG
    Haematologica 93:842-50. 2008
    ..Increases in the incidence of non-Hodgkin's lymphoma and multiple myeloma in the past implicate environmental factors as potential causal agents...
  69. ncbi request reprint Occupational exposures, environmental tobacco smoke, and lung cancer
    Fabrizio Veglia
    Institute for Scientific Interchange ISI Foundation, Turin, Italy
    Epidemiology 18:769-75. 2007
    ..We have studied the association between 52 high-risk job titles and lung cancer incidence in a large prospective study, with more than 200,000 participants followed for more than 6 years and 809 incident cases of lung cancer...
  70. ncbi request reprint Lactase persistence and bitter taste response: instrumental variables and mendelian randomization in epidemiologic studies of dietary factors and cancer risk
    Carlotta Sacerdote
    Centre for cancer Epidemiology and Prevention CPO Piemonte, Turin, Italy
    Am J Epidemiol 166:576-81. 2007
    ..These results suggest that the LCT and TAS2R38 variants are good candidates for Mendelian randomization studies of cancer and other health outcomes...
  71. ncbi request reprint XRCC3 and XPD/ERCC2 single nucleotide polymorphisms and the risk of cancer: a HuGE review
    Maurizio Manuguerra
    Section of Epidemiology, ISI Foundation, Torino, Italy
    Am J Epidemiol 164:297-302. 2006
    ....
  72. ncbi request reprint CYP1A1 T3801 C polymorphism and lung cancer: a pooled analysis of 2451 cases and 3358 controls
    Paolo Vineis
    Universita degli Studi di Torino, Torino, Italy
    Int J Cancer 104:650-7. 2003
    ..The analyses were more inconsistent and failed to reach statistical significance in Asians. This observation might be due to design specificities or unknown effect modifiers in the Asian studies...
  73. pmc Consumption of dairy products and colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Neil Murphy
    Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
    PLoS ONE 8:e72715. 2013
    ..However, less is known about whether the inverse associations vary for individual dairy products with differing fat contents...
  74. pmc Prediagnostic body fat and risk of death from amyotrophic lateral sclerosis: the EPIC cohort
    Valentina Gallo
    Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London, UK
    Neurology 80:829-38. 2013
    ..The aim of this study was to investigate for the first time the association between body fat and risk of amyotrophic lateral sclerosis (ALS) with an appropriate prospective study design...
  75. doi request reprint A risk model for lung cancer incidence
    Clive Hoggart
    Department of Epidemiology and Biostatistics, Imperial College London, St Mary s Campus, Paddington, London, United Kingdom
    Cancer Prev Res (Phila) 5:834-46. 2012
    ..Our model is generalizable and straightforward to implement. Its accuracy can be attributed to its modeling of lifetime exposure to smoking...
  76. doi request reprint Persistent infection by HCV and EBV in peripheral blood mononuclear cells and risk of non-Hodgkin's lymphoma
    Lorenzo Richiardi
    Cancer Epidemiology Unit, CeRMS and CPO Piemonte, University of Turin, Via Santena 7, 10129 Turin, Italy
    Cancer Epidemiol 34:709-12. 2010
    ..These null results, although based on a relatively small sample size, suggest that persistent EBV and HCV infection in the PBMC is not a stronger predictor of NHL risk than serological evidence of infection...
  77. ncbi request reprint Outdoor air pollution and lung cancer: recent epidemiologic evidence
    Paolo Vineis
    Department of Biomedical Sciences and Human Oncology, University of Turin and CPO Piemonte, Turin, Italy
    Int J Cancer 111:647-52. 2004
  78. doi request reprint Smoking and risk for amyotrophic lateral sclerosis: analysis of the EPIC cohort
    Valentina Gallo
    Division of Epidemiology, Public Health and Primary Care, Imperial College London, United Kingdom
    Ann Neurol 65:378-85. 2009
    ..The extensive longitudinal data of the European Prospective Investigation into Cancer and Nutrition (EPIC) were used to evaluate age-specific mortality rates from ALS and the role of cigarette smoking on the risk of dying from ALS...
  79. doi request reprint Occupation and risk of lymphoma: a multicentre prospective cohort study (EPIC)
    David Neasham
    Department of Epidemiology and Public Health, Imperial College, London W2 1PG, UK
    Occup Environ Med 68:77-81. 2011
    ..The relationship between occupation and malignant lymphoma has been investigated in a large European prospective study...
  80. ncbi request reprint Dose-response relationship in tobacco-related cancers of bladder and lung: a biochemical interpretation
    Paolo Vineis
    Department of Biomedical Sciences and Human Oncology, University of Torino and ISI Foundation, Torino, Italy
    Int J Cancer 108:2-7. 2004
  81. doi request reprint Single-nucleotide polymorphisms (5p15.33, 15q25.1, 6p22.1, 6q27 and 7p15.3) and lung cancer survival in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Wei Wei Xun
    Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, St Mary s Campus, Norfolk Place, Paddington, LondonW2 1PG, UK
    Mutagenesis 26:657-66. 2011
    ..1) and rs4324798 (6p22.1) in influencing survival time in lung cancer patients who were never-smokers, based on a small sample...
  82. doi request reprint Immunologic profile of excessive body weight
    Mansour Taghavi Azar Sharabiani
    School of Public Health, Imperial College London, London, UK
    Biomarkers 16:243-51. 2011
    ..0002). We propose that by using this profile-based approach to define immunologic signatures, it might be possible to identify unique immunologic hallmarks of specific types of obesity...
  83. pmc Disease proportions attributable to environment
    Rodolfo Saracci
    Imperial College London, St, Mary s Campus, Norfolk Place W2 1PG, London, UK
    Environ Health 6:38. 2007
    ..The latter aspect is not just a semantic question but carries implications for the focus of preventive actions, whether centred on the material and social environment or on single individuals...
  84. ncbi request reprint Polymorphisms/haplotypes in DNA repair genes and smoking: a bladder cancer case-control study
    Giuseppe Matullo
    Department of Epidemiology and Public Health, Imperial College of Science, Technology and Medicine, Norfolk Place, London W2 1PG, United Kingdom
    Cancer Epidemiol Biomarkers Prev 14:2569-78. 2005
    ..03-0.81). Our results suggest that polymorphisms and/or haplotypes in XRCC3, XRCC1, and PCNA genes and spanning XPD-ERCC1 region may modulate bladder cancer risk and that some of these effects may preferentially affect current smokers...
  85. doi request reprint Physical activity and lymphoid neoplasms in the European Prospective Investigation into Cancer and nutrition (EPIC)
    Catharina M van Veldhoven
    Imperial College London, Dept of Epidemiology and Biostatistics, School of Public Health, St Mary s Campus, Norfolk Place, London W21PG, UK
    Eur J Cancer 47:748-60. 2011
    ..It has been hypothesised that regular exercise may modulate the immune system and thereby reduce the risk of developing the disease...
  86. pmc Bulky DNA adducts in white blood cells: a pooled analysis of 3,600 subjects
    Fulvio Ricceri
    Human Genetics Foundation previously at ISI Foundation, Turin, Italy
    Cancer Epidemiol Biomarkers Prev 19:3174-81. 2010
    ..Factors that have been reported to be related to DNA adduct levels include smoking, diet, body mass index (BMI), genetic polymorphisms, the season of collection of biologic material, and air pollutants...
  87. pmc Assessment of cumulative evidence for the association between glutathione S-transferase polymorphisms and lung cancer: application of the Venice interim guidelines
    Scott M Langevin
    Imperial College London, London
    Pharmacogenet Genomics 20:586-97. 2010
    ....
  88. ncbi request reprint Molecular epidemiology and biomarkers in etiologic cancer research: the new in light of the old
    Paolo Vineis
    Department of Epidemiology and Public Health, Imperial College London, London, United Kingdom
    Cancer Epidemiol Biomarkers Prev 16:1954-65. 2007
    ..There is a need for their systematic validation using principles and criteria established over the past several decades in molecular cancer epidemiology...
  89. pmc STrengthening the Reporting of OBservational studies in Epidemiology - Molecular Epidemiology (STROBE-ME): An Extension of the STROBE Statement
    Valentina Gallo
    Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
    PLoS Med 8:e1001117. 2011
    ..Their guidance covers issues regarding collection, handling and storage of biological samples; laboratory methods, validity and reliability of biomarkers; specificities of study design; and ethical considerations...
  90. ncbi request reprint Validation of biomarkers for the study of environmental carcinogens: a review
    Valentina Gallo
    Department of Epidemiology and Public Health, Imperial College London, London, UK
    Biomarkers 13:505-34. 2008
    ..Immunoassays for the quantification of adducts of N-nitroso compounds are useful for large epidemiological studies, given their sensitivity, the small amount of DNA required and their potential for rapid and high-throughput analysis...
  91. ncbi request reprint Cancer as an evolutionary process at the cell level: an epidemiological perspective
    Paolo Vineis
    Department of Biomedical Sciences and Human Oncology, University of Torino, Via Santena 7, 10126 Torino, Italy and ISI Foundation, Torino, Italy
    Carcinogenesis 24:1-6. 2003
    ....
  92. ncbi request reprint Aromatic amines and cancer
    P Vineis
    Unit of Cancer Epidemiology, Dipartimento di Scienze Biomediche e Oncologia Umana, Torino, Italy
    Cancer Causes Control 8:346-55. 1997
    ..The consistent observation of a difference between men and women in bladder cancer risk, after allowing for known risk factors, suggests consideration of gender-related biological determinants for future investigation...
  93. pmc Occult HCV infection: an unexpected finding in a population unselected for hepatic disease
    Laura De Marco
    Unit of Cancer Epidemiology, C E R M S, University of Turin, Turin, Italy
    PLoS ONE 4:e8128. 2009
    ..Abnormal values of liver enzymes and presence of replicative HCV-RNA in peripheral blood mononuclear cells are also observed. Aim of the study was to evaluate occult HCV occurrence in a population unselected for hepatic disease...
  94. ncbi request reprint Randomized controlled trial: effect of nutritional counselling in general practice
    Carlotta Sacerdote
    CPO Piemonte, Torino, Italy
    Int J Epidemiol 35:409-15. 2006
    ..To investigate the effectiveness of a non-structured 15-min educational intervention by general practitioners (GPs) on modifications of daily diet among healthy adults...
  95. doi request reprint Adherence to the Mediterranean diet is associated with lower abdominal adiposity in European men and women
    Dora Romaguera
    Department of Epidemiology and Public Health, Imperial College London, London W2 1PG, UK
    J Nutr 139:1728-37. 2009
    ....
  96. doi request reprint A stochastic carcinogenesis model incorporating multiple types of genomic instability fitted to colon cancer data
    Mark P Little
    Department of Epidemiology and Public Health, Imperial College Faculty of Medicine, London W21PG, UK
    J Theor Biol 254:229-38. 2008
    ..Given the good fit of the model to this large dataset, it is unlikely that further information on presence of genomic instability or of types of genomic instability can be extracted from age-incidence data by extensions of this model...
  97. doi request reprint HPV-16 infection and cervical cancer: modeling the influence of duration of infection and precancerous lesions
    Iacopo Baussano
    Department of Infectious Disease Epidemiology, St Mary s Campus, Imperial College, London W2 1PG, UK
    Epidemics 2:21-8. 2010
    ....
  98. pmc Alcohol intake and pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium (PanScan)
    Dominique S Michaud
    Division of Epidemiology, Public Health and Primary Care, Imperial College London, London, UK
    Cancer Causes Control 21:1213-25. 2010
    ..87, for 30 or more g/day of alcohol from liquor, compared to none). No associations were noted for wine or beer intake. Overall, no significant increase in risk was observed, but a small effect among heavy drinkers cannot be ruled out...
  99. doi request reprint Modelling patterns of clearance of HPV-16 infection and vaccination efficacy
    Iacopo Baussano
    SCDU di Epidemiologia dei Tumori, Servizio di Statistica Medica, CPO Piemonte, Novara, Italy
    Vaccine 29:1270-7. 2011
    ....
  100. doi request reprint The UK Biobank sample handling and storage protocol for the collection, processing and archiving of human blood and urine
    Paul Elliott
    Department of Epidemiology and Public Health, Faculty of Medicine, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Int J Epidemiol 37:234-44. 2008
    ..The biological samples that are collected and how they are processed and stored will have a major impact on the future scientific usefulness of the UK Biobank resource...
  101. ncbi request reprint The relationship between polymorphisms of xenobiotic metabolizing enzymes and susceptibility to cancer
    Paolo Vineis
    Dipartimento di Scienze Biomediche e Oncologia Umana, Unit of Cancer Epidemiology, University of Torino and ISI Foundation, Via Santena 7, 10126 Torino, Italy
    Toxicology 181:457-62. 2002
    ..In addition, a theoretical approach to the problem of gene-environment interactions at low levels of exposure is offered...