T L Vincent

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. pmc Imaging technologies for preclinical models of bone and joint disorders
    Jordi L Tremoleda
    Biological Imaging Centre BIC, Medical Research Council MRC Clinical Sciences Centre, Imperial College London, Hammersmith Campus, London W12 0NN, UK
    EJNMMI Res 1:11. 2011
  2. pmc Fibroblast growth factor 2: good or bad guy in the joint?
    Tonia L Vincent
    Kennedy Institute of Rheumatology, University of Oxford, 65 Aspenlea Road, London, W6 8LH, UK
    Arthritis Res Ther 13:127. 2011
  3. ncbi request reprint Basic fibroblast growth factor mediates transduction of mechanical signals when articular cartilage is loaded
    Tonia L Vincent
    The Kennedy Institute of Rheumatology, London, UK
    Arthritis Rheum 50:526-33. 2004
  4. ncbi request reprint Basic fibroblast growth factor: an extracellular mechanotransducer in articular cartilage?
    T Vincent
    Kennedy Institute of Rheumatology Division, Imperial College School of Medicine, London, UK
    Biochem Soc Trans 34:456-7. 2006
  5. ncbi request reprint FGF-2 is bound to perlecan in the pericellular matrix of articular cartilage, where it acts as a chondrocyte mechanotransducer
    T L Vincent
    The Kennedy Institute of Rheumatology, Faculty of Medicine, Imperial College School of Science, Technology, and Medicine, London, UK
    Osteoarthritis Cartilage 15:752-63. 2007
  6. ncbi request reprint Induction of interleukin-1 in articular cartilage by explantation and cutting
    Johann Gruber
    Imperial College School of Medicine, London, UK
    Arthritis Rheum 50:2539-46. 2004
  7. ncbi request reprint Is the response of cartilage to injury relevant to osteoarthritis?
    Tonia L Vincent
    Arthritis Rheum 58:1207-10. 2008

Collaborators

Detail Information

Publications7

  1. pmc Imaging technologies for preclinical models of bone and joint disorders
    Jordi L Tremoleda
    Biological Imaging Centre BIC, Medical Research Council MRC Clinical Sciences Centre, Imperial College London, Hammersmith Campus, London W12 0NN, UK
    EJNMMI Res 1:11. 2011
    ..The combined use of imaging modalities also holds significant potential for the assessment of disease pathogenesis in animal models of musculoskeletal disorders, minimising the use of conventional invasive methods and animal redundancy...
  2. pmc Fibroblast growth factor 2: good or bad guy in the joint?
    Tonia L Vincent
    Kennedy Institute of Rheumatology, University of Oxford, 65 Aspenlea Road, London, W6 8LH, UK
    Arthritis Res Ther 13:127. 2011
    ..This balance is dynamic and is altered in disease and following growth factor stimulation in vitro...
  3. ncbi request reprint Basic fibroblast growth factor mediates transduction of mechanical signals when articular cartilage is loaded
    Tonia L Vincent
    The Kennedy Institute of Rheumatology, London, UK
    Arthritis Rheum 50:526-33. 2004
    ..To determine whether the basic fibroblast growth factor (bFGF) mediates signal transduction in articular cartilage in response to mechanical loading...
  4. ncbi request reprint Basic fibroblast growth factor: an extracellular mechanotransducer in articular cartilage?
    T Vincent
    Kennedy Institute of Rheumatology Division, Imperial College School of Medicine, London, UK
    Biochem Soc Trans 34:456-7. 2006
    ..We propose a novel mechanotransduction model, whereby pericellular bFGF, a short distance from the cell surface, becomes available to the cell surface tyrosine kinase receptors when articular cartilage is loaded...
  5. ncbi request reprint FGF-2 is bound to perlecan in the pericellular matrix of articular cartilage, where it acts as a chondrocyte mechanotransducer
    T L Vincent
    The Kennedy Institute of Rheumatology, Faculty of Medicine, Imperial College School of Science, Technology, and Medicine, London, UK
    Osteoarthritis Cartilage 15:752-63. 2007
    ..Arthritis Rheum 2004 Feb;50(2):526-33). Our objectives were to determine where FGF-2 was stored in articular cartilage, to which proteoglycan it was bound, and to elucidate its role in chondrocyte mechanotransduction...
  6. ncbi request reprint Induction of interleukin-1 in articular cartilage by explantation and cutting
    Johann Gruber
    Imperial College School of Medicine, London, UK
    Arthritis Rheum 50:2539-46. 2004
    ..To investigate the effect of explantation and fine cutting of articular cartilage upon intracellular inflammatory signaling pathways and expression of interleukin-1 (IL-1)...
  7. ncbi request reprint Is the response of cartilage to injury relevant to osteoarthritis?
    Tonia L Vincent
    Arthritis Rheum 58:1207-10. 2008