T L Vincent

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. ncbi Fibroblast growth factor 2: good or bad guy in the joint?
    Tonia L Vincent
    Kennedy Institute of Rheumatology, University of Oxford, 65 Aspenlea Road, London, W6 8LH, UK
    Arthritis Res Ther 13:127. 2011
  2. ncbi Basic fibroblast growth factor mediates transduction of mechanical signals when articular cartilage is loaded
    Tonia L Vincent
    The Kennedy Institute of Rheumatology, London, UK
    Arthritis Rheum 50:526-33. 2004
  3. ncbi Basic fibroblast growth factor: an extracellular mechanotransducer in articular cartilage?
    T Vincent
    Kennedy Institute of Rheumatology Division, Imperial College School of Medicine, London, UK
    Biochem Soc Trans 34:456-7. 2006
  4. ncbi FGF-2 is bound to perlecan in the pericellular matrix of articular cartilage, where it acts as a chondrocyte mechanotransducer
    T L Vincent
    The Kennedy Institute of Rheumatology, Faculty of Medicine, Imperial College School of Science, Technology, and Medicine, London, UK
    Osteoarthritis Cartilage 15:752-63. 2007
  5. ncbi Induction of interleukin-1 in articular cartilage by explantation and cutting
    Johann Gruber
    Imperial College School of Medicine, London, UK
    Arthritis Rheum 50:2539-46. 2004
  6. ncbi Is the response of cartilage to injury relevant to osteoarthritis?
    Tonia L Vincent
    Arthritis Rheum 58:1207-10. 2008

Collaborators

Detail Information

Publications6

  1. ncbi Fibroblast growth factor 2: good or bad guy in the joint?
    Tonia L Vincent
    Kennedy Institute of Rheumatology, University of Oxford, 65 Aspenlea Road, London, W6 8LH, UK
    Arthritis Res Ther 13:127. 2011
    ..This balance is dynamic and is altered in disease and following growth factor stimulation in vitro...
  2. ncbi Basic fibroblast growth factor mediates transduction of mechanical signals when articular cartilage is loaded
    Tonia L Vincent
    The Kennedy Institute of Rheumatology, London, UK
    Arthritis Rheum 50:526-33. 2004
    ..To determine whether the basic fibroblast growth factor (bFGF) mediates signal transduction in articular cartilage in response to mechanical loading...
  3. ncbi Basic fibroblast growth factor: an extracellular mechanotransducer in articular cartilage?
    T Vincent
    Kennedy Institute of Rheumatology Division, Imperial College School of Medicine, London, UK
    Biochem Soc Trans 34:456-7. 2006
    ..We propose a novel mechanotransduction model, whereby pericellular bFGF, a short distance from the cell surface, becomes available to the cell surface tyrosine kinase receptors when articular cartilage is loaded...
  4. ncbi FGF-2 is bound to perlecan in the pericellular matrix of articular cartilage, where it acts as a chondrocyte mechanotransducer
    T L Vincent
    The Kennedy Institute of Rheumatology, Faculty of Medicine, Imperial College School of Science, Technology, and Medicine, London, UK
    Osteoarthritis Cartilage 15:752-63. 2007
    ..Arthritis Rheum 2004 Feb;50(2):526-33). Our objectives were to determine where FGF-2 was stored in articular cartilage, to which proteoglycan it was bound, and to elucidate its role in chondrocyte mechanotransduction...
  5. ncbi Induction of interleukin-1 in articular cartilage by explantation and cutting
    Johann Gruber
    Imperial College School of Medicine, London, UK
    Arthritis Rheum 50:2539-46. 2004
    ..Biologically active IL-1alpha protein was detectable in cartilage lysates and was probably intracellular proIL-1alpha. We were unable to show that IL-1 was secreted by chondrocytes...
  6. ncbi Is the response of cartilage to injury relevant to osteoarthritis?
    Tonia L Vincent
    Arthritis Rheum 58:1207-10. 2008