Affiliation: Imperial College
- Iron, haemochromatosis and thalassaemia as risk factors for fibrosis in hepatitis C virus infectionMark Thursz
Gastroenterology and Hepatology Research, Imperial College St Mary s Hospital Campus, Norfolk Place, London W2 1NY, UK
Gut 56:613-4. 2007
- Understanding the host genetics of chronic hepatitis B and CMark Thursz
Hepatology and Gastroenterology Section, Department of Medicine, Imperial College, London, United Kingdom
Semin Liver Dis 31:115-27. 2011..Indeed, stratification of clinical trial populations based on IL-28B genotype is already considered mandatory...
- The diversity and management of chronic hepatitis B virus infections in the United Kingdom: a wake-up callRichard S Tedder
Microbiology Services Colindale, Health Protection Agency, London, UK
Clin Infect Dis 56:951-60. 2013..Through migration, diversity of chronic hepatitis B virus (HBV) infection has changed, affecting disease burden and control. We describe clinical and viral characteristics of chronic HBV in the United Kingdom...
- Natural NS3 resistance polymorphisms occur frequently prior to treatment in HIV-positive patients with acute hepatitis CMayke Leggewie
aMRC Centre for Virus Research, University of Glasgow, Glasgow bDepartment of Virology, Imperial College NHS Trust cDepartment of Medicine, Imperial College London, London, UK
AIDS 27:2485-8. 2013..Low-frequency mutations were detected in all samples. Further studies are required to determine threshold levels associated with treatment failure. ..
- Blunted increase in serum hepcidin as response to oral iron in HFE-hemochromatosisArvind Sangwaiya
Department of Gastroenterology, Ealing Hospital NHS Trust, London, UK
Eur J Gastroenterol Hepatol 23:721-4. 2011..However, the precise link between hepcidin levels and iron absorption in HFE-H patients has been poorly understood...
- NICE guidelines and a treatment algorithm for the management of chronic hepatitis B: a review of 12 years experience in west LondonPatrick T F Kennedy
Department of Hepatology, Imperial College London at St Mary s Hospital, London, UK
Antivir Ther 13:1067-76. 2008....
- Quantitative versus morphological assessment of liver fibrosis: semi-quantitative scores are more robust than digital image fibrosis area estimationMark Wright
Hepatology Section, Faculty of Medicine, Imperial College, London W2 1NY, UK
Liver Int 23:28-34. 2003..Accurate determination of a threshold greyscale level representing fibrous tissue is critical. This method has not been fully evaluated in clinical practice...
- Association of genetic variants of the chemokine receptor CCR5 and its ligands, RANTES and MCP-2, with outcome of HCV infectionSimon Hellier
The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
Hepatology 38:1468-76. 2003..018, OR: 2.29, 95% CI: 1.14-4.58). In conclusion, our study suggests a possible role of the polymorphisms CCR5-delta32, RANTES -403, and MCP-2 Q46K in the outcome of HCV infection...
- Autoregulatory role of interleukin-10 in hepatitis C patients treated with IFN-alphaArmin Luik
University of Mainz, Department of Medicine, 55101 Mainz, Germany
J Interferon Cytokine Res 24:585-93. 2004..This suggests an autoregulatory role of IL-10 in IFN therapy...