Emma C Thomson
Affiliation: Imperial College
- The natural history of early hepatitis C virus evolution; lessons from a global outbreak in human immunodeficiency virus-1-infected individualsEmma C Thomson
Peter Medawar Building for Pathogen Research, University of Oxford, South Parks Road, Oxford OX1 3SY, UK
J Gen Virol 92:2227-36. 2011....
- Epidemiology of hepatitis C virus infection in HIV-infected individualsEmma C Thomson
Department of Hepatology, Faculty of Medicine, Imperial College at St Mary s Hospital, London, UK
J Viral Hepat 15:773-81. 2008..The management of these patients is further complicated by potential interactions between antiretroviral therapy and peginterferon and ribavirin...
- Predicting spontaneous clearance of acute hepatitis C virus in a large cohort of HIV-1-infected menEmma C Thomson
Department of Hepatology, Wright Fleming Institute, Faculty of Medicine, Imperial College London, London, UK
Gut 60:837-45. 2011..The aim of this study was to characterise the natural history of primary HCV in this setting and to assess host and viral factors which predict spontaneous clearance...
- Delayed anti-HCV antibody response in HIV-positive men acutely infected with HCVEmma C Thomson
Department of Virology, Wright Fleming Institute, Imperial College, London, UK
AIDS 23:89-93. 2009....
- Dynamic coinfection with multiple viral subtypes in acute hepatitis CJennifer A Smith
Institute for Emerging Infections, University of Oxford, Oxford, UK
J Infect Dis 202:1770-9. 2010..Hypervariable region 1 (HVR1) is genetically diverse and under selective pressure from the host immune response. We analyzed HVR1 evolution by frequent sampling of an acutely infected HCV cohort...
- Natural NS3 resistance polymorphisms occur frequently prior to treatment in HIV-positive patients with acute hepatitis CMayke Leggewie
aMRC Centre for Virus Research, University of Glasgow, Glasgow bDepartment of Virology, Imperial College NHS Trust cDepartment of Medicine, Imperial College London, London, UK
AIDS 27:2485-8. 2013..Low-frequency mutations were detected in all samples. Further studies are required to determine threshold levels associated with treatment failure. ..
- Diagnosing acute hepatitis C in HIV-infected patients: nucleic acid testing compared with antibody and antigen-antibody detecting methodsEleni Nastouli
Department of Virology, Imperial College Healthcare NHS Trust, St Mary s Hospital, Praed Street, London W2 1NY, United Kingdom
J Clin Virol 44:78-80. 2009..Little is known about the performance of routine antibody-only tests, compared with newer serological antigen-antibody detection assays and nucleic acid testing in this patient group...
- B-cell depletion reveals a role for antibodies in the control of chronic HIV-1 infectionKuan Hsiang G Huang
Nuffield Department of Medicine and NIHR Biomedical Research Centre, Oxford Martin School, Peter Medawar Building for Pathogen Research, University of Oxford, South Parks Road, Oxford OX1 3SY, UK
Nat Commun 1:102. 2010..These data suggest that B-cell function can contribute to the long-term control of pVL, and that NAbs may be more important in controlling chronic HIV-1 infection than previously suspected...
- Advances in hepatitis B and CEmma C Thomson
St Mary s Hospital, Praed Street, London W2 1NY, UK
Curr Opin Infect Dis 17:449-59. 2004....