P P Tekkis

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. doi request reprint Measuring sexual and urinary outcomes in women after rectal cancer excision
    P P Tekkis
    Department of Colorectal Surgery, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Dis Colon Rectum 52:46-54. 2009
  2. doi request reprint Ileal pouch dysfunction: diagnosis and management
    Paris P Tekkis
    Department of Academic Surgery, Chelsea and Westminster Hospital, Division of Surgery, Oncology, Reproductive Biology, and Anaesthetics, Imperial College, Fulham Road, London, SW10 9NH, UK
    Gastroenterol Clin North Am 37:669-83, ix. 2008
  3. ncbi request reprint A national study on lymph node retrieval in resectional surgery for colorectal cancer
    Paris P Tekkis
    Department of Biosurgery and Surgical Technology, Imperial College London, St Mary s Hospital, London, United Kingdom
    Dis Colon Rectum 49:1673-83. 2006
  4. ncbi request reprint A comparison of segmental vs subtotal/total colectomy for colonic Crohn's disease: a meta-analysis
    P P Tekkis
    Imperial College London, Department of Surgical Oncology and Technology, UK
    Colorectal Dis 8:82-90. 2006
  5. doi request reprint Development of a pouch functional score following restorative proctocolectomy
    R E Lovegrove
    Department of Biosurgery and Surgical Technology, Imperial College London, London, UK
    Br J Surg 97:945-51. 2010
  6. ncbi request reprint Comparison of colonic stenting and open surgery for malignant large bowel obstruction
    H S Tilney
    Department of Biosurgery and Surgical Technology, Imperial College London, St Mary s Hospital, 10th Floor QEQM Building, Praed Street, London, W2 1NY, UK
    Surg Endosc 21:225-33. 2007
  7. doi request reprint A comparison of pancreaticoduodenectomy with extended pancreaticoduodenectomy: a meta-analysis of 1909 patients
    N Iqbal
    Barts and The London HPB Centre, The Royal London Hospital, Whitechapel, London, UK
    Eur J Surg Oncol 35:79-86. 2009
  8. ncbi request reprint Meta-analysis of short-term and long-term outcomes of J, W and S ileal reservoirs for restorative proctocolectomy
    R E Lovegrove
    Imperial College London, Department of Biosurgery and Surgical Technology, St Mary s Hospital, London, UK
    Colorectal Dis 9:310-20. 2007
  9. doi request reprint Long-term failure and function after restorative proctocolectomy - a multi-centre study of patients from the UK National Ileal Pouch Registry
    P P Tekkis
    Department of Biosurgery and Surgical Technology, St Mary s Hospital, Imperial College, London, UK
    Colorectal Dis 12:433-41. 2010
  10. doi request reprint Volume analysis of outcome following restorative proctocolectomy
    E M Burns
    Department of Surgery, Imperial College London, St Mary s Hospital, London, UK
    Br J Surg 98:408-17. 2011

Collaborators

Detail Information

Publications101 found, 100 shown here

  1. doi request reprint Measuring sexual and urinary outcomes in women after rectal cancer excision
    P P Tekkis
    Department of Colorectal Surgery, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Dis Colon Rectum 52:46-54. 2009
    ..This study was designed to investigate sexual and urinary dysfunction in women who underwent rectal cancer excision, and the influence of tumor and treatment variables on long-term outcomes...
  2. doi request reprint Ileal pouch dysfunction: diagnosis and management
    Paris P Tekkis
    Department of Academic Surgery, Chelsea and Westminster Hospital, Division of Surgery, Oncology, Reproductive Biology, and Anaesthetics, Imperial College, Fulham Road, London, SW10 9NH, UK
    Gastroenterol Clin North Am 37:669-83, ix. 2008
    ..This major advance has offered an alternative to permanent ileostomy in these patients...
  3. ncbi request reprint A national study on lymph node retrieval in resectional surgery for colorectal cancer
    Paris P Tekkis
    Department of Biosurgery and Surgical Technology, Imperial College London, St Mary s Hospital, London, United Kingdom
    Dis Colon Rectum 49:1673-83. 2006
    ..This study was designed to develop a mathematical model for predicting the number of lymph nodes harvested in bowel cancer resection specimens based on the current clinical practice in the United Kingdom...
  4. ncbi request reprint A comparison of segmental vs subtotal/total colectomy for colonic Crohn's disease: a meta-analysis
    P P Tekkis
    Imperial College London, Department of Surgical Oncology and Technology, UK
    Colorectal Dis 8:82-90. 2006
    ....
  5. doi request reprint Development of a pouch functional score following restorative proctocolectomy
    R E Lovegrove
    Department of Biosurgery and Surgical Technology, Imperial College London, London, UK
    Br J Surg 97:945-51. 2010
    ..The influence of function on quality of life after primary restorative proctocolectomy (RPC) was determined with the aim of developing a pouch functional score...
  6. ncbi request reprint Comparison of colonic stenting and open surgery for malignant large bowel obstruction
    H S Tilney
    Department of Biosurgery and Surgical Technology, Imperial College London, St Mary s Hospital, 10th Floor QEQM Building, Praed Street, London, W2 1NY, UK
    Surg Endosc 21:225-33. 2007
    ..The current study compared the outcomes of stents and open surgery in the management of malignant large bowel obstruction...
  7. doi request reprint A comparison of pancreaticoduodenectomy with extended pancreaticoduodenectomy: a meta-analysis of 1909 patients
    N Iqbal
    Barts and The London HPB Centre, The Royal London Hospital, Whitechapel, London, UK
    Eur J Surg Oncol 35:79-86. 2009
    ..To compare outcomes between pancreaticoduodenectomy (PD) and extended pancreaticoduodenectomy (EPD) from all published comparative studies in the literature...
  8. ncbi request reprint Meta-analysis of short-term and long-term outcomes of J, W and S ileal reservoirs for restorative proctocolectomy
    R E Lovegrove
    Imperial College London, Department of Biosurgery and Surgical Technology, St Mary s Hospital, London, UK
    Colorectal Dis 9:310-20. 2007
    ..The choice of ileal pouch reservoir has been a contentious subject with no consensus as to which technique provides better function. This study aimed to compare short- and long-term outcomes of three ileal reservoir designs...
  9. doi request reprint Long-term failure and function after restorative proctocolectomy - a multi-centre study of patients from the UK National Ileal Pouch Registry
    P P Tekkis
    Department of Biosurgery and Surgical Technology, St Mary s Hospital, Imperial College, London, UK
    Colorectal Dis 12:433-41. 2010
    ..There is little information on the long-term failure and function after restorative proctocolectomy (RPC). The results of data submitted to a national registry were analysed...
  10. doi request reprint Volume analysis of outcome following restorative proctocolectomy
    E M Burns
    Department of Surgery, Imperial College London, St Mary s Hospital, London, UK
    Br J Surg 98:408-17. 2011
    ..This observational study aimed to determine national provision and outcome following pouch surgery (restorative proctocolectomy, RPC) and to examine the effect of institutional and surgeon caseload on outcome...
  11. doi request reprint A randomized, controlled trial of narrow-band imaging vs high-definition white light for adenoma detection in patients at high risk of adenomas
    J E East
    Wolfson Unit for Endoscopy, St Mark s Hospital, Imperial College London, London, UK
    Colorectal Dis 14:e771-8. 2012
    ..High risk was defined as three or more adenomas at last colonoscopy, history of colorectal cancer and positive faecal occult blood test...
  12. ncbi request reprint Diagnostic precision of magnetic resonance imaging for preoperative prediction of the circumferential margin involvement in patients with rectal cancer
    S Purkayastha
    Department of Biosurgery and Surgical Technology, St Mary s Hospital, Imperial College, London, UK
    Colorectal Dis 9:402-11. 2007
    ..This meta-analysis aims at evaluating the diagnostic precision of magnetic resonance imaging (MRI) for the preoperative evaluation of CMI in patients with rectal cancer...
  13. ncbi request reprint Extending the horizons of restorative rectal surgery: intersphincteric resection for low rectal cancer
    H S Tilney
    Department of Biosurgery and Surgical Technology, St Mary s Hospital, Imperial College London, London, UK
    Colorectal Dis 10:3-15; discussion 15-6. 2008
    ..The present study examines the indications, techniques and outcomes following ISR...
  14. ncbi request reprint Magnetic resonance colonography vs computed tomography colonography for the diagnosis of colorectal cancer: an indirect comparison
    S Purkayastha
    Department of Biosurgery and Surgical Technology, Imperial College, St Mary s Hospital, London, UK
    Colorectal Dis 9:100-11. 2007
    ....
  15. ncbi request reprint Laparoscopic vs open subtotal colectomy for benign and malignant disease
    H S Tilney
    Department of Biosurgery and Surgical Technology, Imperial College, London, UK
    Colorectal Dis 8:441-50. 2006
    ..The present meta-analysis aims to compare short-term and long-term outcomes in patients undergoing laparoscopic or open subtotal colectomy for benign and malignant disease...
  16. ncbi request reprint Meta-analysis of observational studies of ileorectal versus ileal pouch-anal anastomosis for familial adenomatous polyposis
    O Aziz
    Department of Surgical Oncology and Technology, Imperial College London, St Mary s Hospital, London, UK
    Br J Surg 93:407-17. 2006
    ..Colectomy with ileorectal anastomosis and proctocolectomy with ileal pouch-anal anastomosis both offer this, but there is no clear consensus about which is better...
  17. doi request reprint An open study of maintenance antibiotic therapy for chronic antibiotic-dependent pouchitis: efficacy, complications and outcome
    S D McLaughlin
    Department of Biosurgery and Surgical Technology, Imperial College, Chelsea and Westminster Hospital, London, UK
    Colorectal Dis 13:438-44. 2011
    ..About 5% of restorative proctocolectomy (RPC) patients develop chronic antibiotic-dependent pouchitis. These require antibiotic maintenance therapy. We report our experience in managing this patient group...
  18. doi request reprint Review article: restorative proctocolectomy, indications, management of complications and follow-up--a guide for gastroenterologists
    S D McLaughlin
    Department of Biosurgery and Surgical Technology, Imperial College London, London, UK
    Aliment Pharmacol Ther 27:895-909. 2008
    ..Gastroenterologists are increasingly involved in the management of patients following restorative proctocolectomy...
  19. ncbi request reprint Long-term, health-related, quality of life comparison in patients undergoing single stage vs staged resection for complicated diverticular disease
    V A Constantinides
    Imperial College London, Department of Surgical Oncology and Technology, St Mary s Hospital, London, United Kingdom
    Colorectal Dis 8:663-71. 2006
    ..To evaluate long-term health-related quality of life, for single-staged and staged resections following reversal, for complicated diverticular disease...
  20. ncbi request reprint Comparison of outcomes of ileal pouch-anal anastomosis for familial adenomatous polyposis with and without previous ileorectal anastomosis
    A C von Roon
    The Polyposis Registry and Department of Surgery, St Mark s Hospital, Harrow, London, UK
    Br J Surg 95:494-8. 2008
    ..This retrospective study re-examined the question in a single centre...
  21. doi request reprint A selective approach to restorative proctocolectomy without ileostomy: a single centre experience
    R E Lovegrove
    Department of Biosurgery and Surgical Technology, Imperial College London, London, UK
    Colorectal Dis 10:916-24. 2008
    ..A single surgeon series on complications and functional outcomes following restorative proctocolectomy (RPC) is presented...
  22. doi request reprint Adjuvant chemotherapy improves overall survival after TME surgery in mucinous carcinoma of the rectum
    M Chand
    Royal Marsden Hospital, Fulham Road, London, United Kingdom Croydon University Hospital, London Road, Croydon, United Kingdom Imperial College, Department of Cancer and Surgery, London, United Kingdom Electronic address
    Eur J Surg Oncol 40:240-5. 2014
    ..This study evaluated the 5-year overall survival of patients with mucinous rectal cancer following optimal TME surgery to determine whether adjuvant chemotherapy conferred a survival benefit...
  23. doi request reprint Narrow band imaging with magnification for the characterization of small and diminutive colonic polyps: pit pattern and vascular pattern intensity
    J E East
    Wolfson Unit for Endoscopy, St Mark s Hospital, Imperial College London, London, UK
    Endoscopy 40:811-7. 2008
    ..We aimed to assess whether the Kudo pit pattern classification is accurate when used with NBI (without dye-spray), and if microvascular appearances or NBI pit patterns maintain accuracy for polyp characterization at sizes < 10 mm...
  24. ncbi request reprint Social deprivation and outcomes in colorectal cancer
    J J Smith
    Department of Surgery, West Middlesex Hospital, Isleworth, and Department of Biosurgery and Surgical Technology, Imperial College London, UK
    Br J Surg 93:1123-31. 2006
    ..The aim of this study was to examine the influence of social deprivation on postoperative mortality and length of stay in patients having surgery for colorectal cancer...
  25. ncbi request reprint Risk factors predicting intra-abdominal desmoids in familial adenomatous polyposis: a single centre experience
    A Sinha
    St Mark s Hospital and Imperial College, London, HA1 3UJ, UK
    Tech Coloproctol 14:141-6. 2010
    ..Since the morbidity and mortality due to desmoids is almost entirely attributable to IAD, we aimed to identify specifically risk factors predicting IAD development in FAP...
  26. doi request reprint Outcomes of simultaneous resections for patients with synchronous colorectal liver metastases
    A A P Slesser
    Division of Surgery and Cancer, Imperial College, Chelsea and Westminster Campus, Fulham Road, London, UK Department of Colorectal Surgery, The Royal Marsden Hospital, UK Electronic address
    Eur J Surg Oncol 39:1384-93. 2013
    ..The aim of this study was to determine the outcomes associated with simultaneous resections compared to patients undergoing sequential resections for synchronous colorectal liver metastases...
  27. doi request reprint Exclusive elemental diet impacts on the gastrointestinal microbiota and improves symptoms in patients with chronic pouchitis
    S D McLaughlin
    Department of Gastroenterology, St Mark s Hospital, London, United Kingdom
    J Crohns Colitis 7:460-6. 2013
    ..Elemental diet is effective treatment for Crohn's disease. Since pouchitis shares some similarities to Crohn's disease we hypothesised that elemental diet may be an effective treatment...
  28. doi request reprint Laparoscopically assisted vs. open elective colonic and rectal resection: a comparison of outcomes in English National Health Service Trusts between 1996 and 2006
    O Faiz
    Department of Surgical Oncology and Technology, St Mary s National Health Service Trust, London, United Kingdom
    Dis Colon Rectum 52:1695-704. 2009
    ..This study was designed to compare outcomes after elective laparoscopic and conventional colorectal surgery over a ten-year period using data from the English National Health Service Hospital Episode Statistics database...
  29. doi request reprint An open study of antibiotics for the treatment of pre-pouch ileitis following restorative proctocolectomy with ileal pouch-anal anastomosis
    S D McLaughlin
    Department of Biosurgery and Surgical Technology, Imperial College London, Loondon, UK
    Aliment Pharmacol Ther 29:69-74. 2009
    ..Its aetiology remains unknown and only one study has reported the effect of treatment. We report a series of fourteen patients treated and followed up with repeat pouchoscopy...
  30. ncbi request reprint EMVI-positive stage II rectal cancer has similar clinical outcomes as stage III disease following pre-operative chemoradiotherapy
    M Chand
    Department of GI Cancer, Royal Marsden Hospital, Fulham Road, London
    Ann Oncol 25:858-63. 2014
    ..This study examined the outcomes of patients with stage II and III rectal cancer to determine whether EMVI status influences disease-free survival (DFS)...
  31. doi request reprint Study of sexual, urinary, and fecal function in females following restorative proctocolectomy
    Julie Cornish
    Department of Biosurgery and Surgical Technology, St Mary s Hospital, Imperial College, London, UK
    Inflamm Bowel Dis 18:1601-7. 2012
    ..The aim was to investigate quality of life, sexual, fecal, and urinary function in females undergoing restorative proctocolectomy (RPC)...
  32. doi request reprint Risk factors predicting desmoid occurrence in patients with familial adenomatous polyposis: a meta-analysis
    A Sinha
    St Mark s Hospital and Imperial College, London, UK
    Colorectal Dis 13:1222-9. 2011
    ..Several small series have analysed the incidence of DT and predisposing risk factors. Using meta-analytical techniques, this study aimed to identify risk factors for DT development in patients with FAP...
  33. doi request reprint A cost-effectiveness analysis of delayed sphincteroplasty for anal sphincter injury
    E K Tan
    Department of Biosurgery and Surgical Technology, St Mary s Hospital, Imperial College, London, UK
    Colorectal Dis 10:653-62. 2008
    ..This study aimed to determine the cost to patient and health service in the event a DS is performed...
  34. doi request reprint The National Bowel Cancer Audit Project: what do trusts think of the National Bowel Cancer Audit and how can it be improved?
    J A Cornish
    Department of Biosurgery and Surgical Technology, St Mary s Hospital, Imperial College, 10th Floor QEQM Wing, Praed Street, London W2 1NY, UK
    Tech Coloproctol 15:53-9. 2011
    ..The aims of this study were to understand why trusts were/were not participating in the NBOCAP and how to improve the quality of data collected and feedback...
  35. doi request reprint The national bowel cancer audit project: the impact of organisational structure on outcome in operative bowel cancer within the United Kingdom
    J A Cornish
    Department of Biosurgery and Surgical Technology, Imperial College, London, UK
    Surg Oncol 20:e72-7. 2011
    ..To investigate the relationship between organisational structure, process and surgical outcomes for bowel cancer surgery...
  36. ncbi request reprint Comparison of laparoscopic and open ileocecal resection for Crohn's disease: a metaanalysis
    H S Tilney
    Department of Surgical Oncology and Technology, Imperial College London, St Mary s Hospital, 10th Floor QEQM Building, Praed Street, London, W2 1NY, UK
    Surg Endosc 20:1036-44. 2006
    ..The role of laparoscopic surgery for patients with ileocecal Crohn's disease is a contentious issue. This metaanalysis aimed to compare open resection with laparoscopically assisted resection for ileocecal Crohn's disease...
  37. ncbi request reprint Risk factors associated with ileal pouch-related fistula following restorative proctocolectomy
    P P Tekkis
    Department of Colorectal Surgery, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Br J Surg 92:1270-6. 2005
    ..Pouch-related fistula occurs in 5-10 per cent of patients after restorative proctocolectomy. The present study identified risk factors associated with the development of such fistulas...
  38. ncbi request reprint The management of rectal cancer with synchronous liver metastases: a modern surgical dilemma
    A A P Slesser
    Department of Colorectal Surgery, The Royal Marsden Hospital, Fulham Road, London, UK
    Tech Coloproctol 17:1-12. 2013
    ..We present an up-to-date review of the different surgical strategies available for rectal cancer patients with synchronous colorectal liver metastases...
  39. doi request reprint A comparative study of standard vs. high definition colonoscopy for adenoma and hyperplastic polyp detection with optimized withdrawal technique
    J E East
    Wolfson Unit for Endoscopy, St Mark s Hospital, Imperial College London, London, UK
    Aliment Pharmacol Ther 28:768-76. 2008
    ..Colonoscopy has a known miss rate for polyps and adenomas. High definition (HD) colonoscopes may allow detection of subtle mucosal change, potentially aiding detection of adenomas and hyperplastic polyps...
  40. doi request reprint The role of laparoscopy and laparoscopic ultrasound in the preoperative staging of pancreatico-biliary cancers--A meta-analysis
    D Hariharan
    Queen Mary University of London, Institute of Cancer, Barts and the London School of Medicine and Dentistry, London, UK
    Eur J Surg Oncol 36:941-8. 2010
    ..Staging laparoscopy (SL) may prevent non-therapeutic laparotomy in patients with otherwise resectable pancreatico-biliary cancers, but evidence is inconclusive. This meta-analysis aims to ascertain the true benefit of SL...
  41. ncbi request reprint Meta-analysis: Alvimopan vs. placebo in the treatment of post-operative ileus
    E K Tan
    Department of Biosurgery and Surgical Technology, St Mary s Hospital, Imperial College, London, UK
    Aliment Pharmacol Ther 25:47-57. 2007
    ..Alvimopan is a selective, competitive mu-opioid receptor antagonist with limited oral bioavailability which may be used to reduce length of post-operative ileus...
  42. ncbi request reprint Prospective multicentre evaluation of adverse outcomes following treatment for complicated diverticular disease
    V A Constantinides
    Imperial College London, Department of Surgical Oncology and Technology, St Mary s Hospital, London, UK
    Br J Surg 93:1503-13. 2006
    ..The aim of this study was to investigate adverse events following restorative (primary resection and anastomosis, PRA) and non-restorative (Hartmann's procedure, HP) surgery for complicated diverticular disease...
  43. doi request reprint Extended spectrum beta-lactamase-producing bacteria and Clostridium difficile in patients with pouchitis
    S D McLaughlin
    Department of Gastroenterology, St Mark s Hospital, London, UK
    Aliment Pharmacol Ther 32:664-9. 2010
    ..Clostridium difficile and ESBL are resistant to many antibiotics and each may cause pouchitis after restorative proctocolectomy (RPC) refractory to empirical antibiotic therapy...
  44. ncbi request reprint Systematic review and meta-analysis of trainee- versus expert surgeon-performed colorectal resection
    M Kelly
    Faculty of Medicine, Imperial College London, London, UK
    Br J Surg 101:750-9. 2014
    ..The aim of this meta-analysis was to compare short-term and oncological outcomes following colorectal resection performed by surgical trainees and expert surgeons...
  45. pmc Extramural venous invasion is a potential imaging predictive biomarker of neoadjuvant treatment in rectal cancer
    M Chand
    1 Department of GI Radiology, Royal Marsden Hospital, Downs Road, Sutton, SM2 5PT, UK 2 Department of Surgery and Cancer, Imperial College, London, UK 3 Department of Surgery, Croydon University Hospital, London Road, Croydon CR7 7YE, UK
    Br J Cancer 110:19-25. 2014
    ..This study aimed to demonstrate that regression of mrEMVI following neoadjuvant chemoradiotherapy (CRT) results in improved outcomes and mrEMVI can be used as an imaging biomarker...
  46. doi request reprint Development of a social morbidity score in patients with chronic ulcerative colitis as a potential guide to treatment
    J J Smith
    Department of Colorectal Surgery, West Middlesex University Hospital, Isleworth, Middlesex, UK
    Colorectal Dis 14:e250-7. 2012
    ..We have developed a new Social Impact of Chronic Conditions - Inflammatory Bowel Disease (SICC-IBD) questionnaire to assess these areas...
  47. doi request reprint Meta-analysis: narrow band imaging for lesion characterization in the colon, oesophagus, duodenal ampulla and lung
    J E East
    Wolfson Unit for Endoscopy, St Mark s Hospital, Imperial College London, London
    Aliment Pharmacol Ther 28:854-67. 2008
    ..Narrow band imaging is a new endoscopic technology that highlights mucosal surface structures and microcapillaries, which may be indicative of neoplastic change...
  48. ncbi request reprint Meta-analysis of colonic reservoirs versus straight coloanal anastomosis after anterior resection
    A G Heriot
    Department of Surgical Oncology and Technology, Imperial College London, St Mary s Hospital, London, UK
    Br J Surg 93:19-32. 2006
    ..A random-effect model was used to aggregate the study endpoints and assess heterogeneity...
  49. pmc The bacterial pathogenesis and treatment of pouchitis
    S D McLaughlin
    Chelsea and Westminster Hospital, London SW10 9NH, UK
    Therap Adv Gastroenterol 3:335-48. 2010
    ..Antibiotic treatment remains the most studied and is the mainstay of treatment. In this article we review the aetiology of pouchitis and the evidenced-based treatment options...
  50. doi request reprint Female infertility following restorative proctocolectomy
    J A Cornish
    Department of Biosurgery and Surgical Technology, St Mary s Hospital, Imperial College, London, UK
    Colorectal Dis 13:e339-44. 2011
    ..Females of child-bearing age have been reported to have a two to three-fold increase in infertility after restorative proctocolectomy (RPC). This study aimed to assess aspects of infertility and pregnancy...
  51. ncbi request reprint Magnetic resonance colonography versus colonoscopy as a diagnostic investigation for colorectal cancer: a meta-analysis
    S Purkayastha
    Department of Surgical Oncology, Imperial College of Science, Technology and Medicine, St Mary s Hospital, London, UK
    Clin Radiol 60:980-9. 2005
    ..A meta-analysis reporting the use of MRC is yet to be performed. The aim of this study was to evaluate the diagnostic accuracy of MRC compared with the gold-standard investigation, conventional colonoscopy (CC)...
  52. ncbi request reprint Surgical strategies for faecal incontinence--a decision analysis between dynamic graciloplasty, artificial bowel sphincter and end stoma
    E K Tan
    Department of Biosurgery and Surgical Technology, Imperial College London, St Mary s Hospital, London, UK
    Colorectal Dis 10:577-86. 2008
    ..FI may affect quality of life (QOL) so severely that patients are often willing to consider a permanent end stoma (ES). It is unclear which is the more cost-effective strategy...
  53. doi request reprint A systematic review of anal squamous cell carcinoma in inflammatory bowel disease
    A A P Slesser
    Division of Surgery and Cancer, Chelsea and Westminster Campus, Imperial College London, UK Department of Colorectal Surgery, The Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK
    Surg Oncol 22:230-7. 2013
    ..The aim of this systematic review was to determine the incidence, aetiology and clinical characteristics of anal squamous cell carcinomas (SCC) presenting in patients with inflammatory bowel disease...
  54. doi request reprint Diverticular disease hospital admissions are increasing, with poor outcomes in the elderly and emergency admissions
    S Jeyarajah
    Department of Colorectal Surgery, King s College Hospital, London, UK
    Aliment Pharmacol Ther 30:1171-82. 2009
    ..Diverticular disease has a changing disease pattern with limited epidemiological data...
  55. ncbi request reprint Artificial neural networks: useful aid in diagnosing acute appendicitis
    S G Prabhudesai
    Department of Biosurgery and Surgical Technology, Faculty of Medicine, Imperial College London, St Mary s Hospital Campus, Room 1029, 10th Floor QEQM Building, Praed Street, London, W2 1NY, UK
    World J Surg 32:305-9; discussion 310-1. 2008
    ....
  56. ncbi request reprint Strictureplasty vs resection in small bowel Crohn's disease: an evaluation of short-term outcomes and recurrence
    G E Reese
    Department of Biosurgery and Surgical Technology, St Mary s Hospital, Imperial College London, London, UK
    Colorectal Dis 9:686-94. 2007
    ..To compare postoperative adverse events and recurrence following strictureplasty or bowel resection in patients with small bowel Crohn's disease (CD)...
  57. doi request reprint A comparison of pancreaticoduodenectomy with pylorus preserving pancreaticoduodenectomy: a meta-analysis of 2822 patients
    N Iqbal
    Barts and The London HPB Centre, The Royal London Hospital, London, UK
    Eur J Surg Oncol 34:1237-45. 2008
    ..The gold-standard for surgical excision of peri-ampullary tumours has not been established despite numerous studies, due to conflicting outcomes...
  58. doi request reprint A meta-analysis comparing simultaneous versus delayed resections in patients with synchronous colorectal liver metastases
    A A P Slesser
    Department of Colorectal Surgery, The Royal Marsden Hospital, Fulham Road, London, UK
    Surg Oncol 22:36-47. 2013
    ..The aim of this study was to use a meta-analytical model to compare the short-term and long-term outcomes in patients with synchronous colorectal liver metastases (SCLM) undergoing simultaneous resections versus delayed resections...
  59. pmc Pelvic colorectal recurrence: crucial role of radiologists in oncologic and surgical treatment options
    P A Georgiou
    Department of Colorectal Surgery, The Royal Marsden Hospital, Fulham Road, London, UK
    Cancer Imaging 11:S103-11. 2011
    ..This review describes the methods of staging patients with locally advanced primary and recurrent rectal cancer prior to surgery emphasizing the role that radiologists have in this process...
  60. ncbi request reprint Chest pain following oesophageal stenting for malignant dysphagia
    M Golder
    Department of General Surgery, University Hospital Lewisham, London, UK
    Clin Radiol 56:202-5. 2001
    ..As the origin of the pain is still unknown, pre-emptive analgesia may a play role in reducing stent-related morbidity and possibly in-hospital stay...
  61. pmc A meta-analysis on the influence of inflammatory bowel disease on pregnancy
    J Cornish
    Department of Biosurgery and Surgical Technology, St Mary s Hospital, Imperial College, 10th Floor QEQM Wing, Praed Street, London W2 1NY, UK
    Gut 56:830-7. 2007
    ..Inflammatory bowel disease (IBD) has a typical onset during the peak reproductive years. Evidence of the risk of adverse pregnancy outcomes in IBD is important for the management of pregnancy to assist in its management...
  62. ncbi request reprint Risk-adjusted prediction of operative mortality in oesophagogastric surgery with O-POSSUM
    P P Tekkis
    Academic Department of Surgery, King s College Hospital, London, UK
    Br J Surg 91:288-95. 2004
    ..The present study was designed to develop a dedicated oesophagogastric model for the prediction of risk-adjusted postoperative mortality in upper gastrointestinal surgery (O-POSSUM)...
  63. ncbi request reprint Conversion rates in laparoscopic colorectal surgery: a predictive model with, 1253 patients
    P P Tekkis
    Department of Colorectal Surgery and the Minimally Invasive Surgery Center, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Surg Endosc 19:47-54. 2005
    ..This study aimed all develop a mathematical model for predicting the conversion rate for patients undergoing laparoscopic colorectal surgery...
  64. doi request reprint To divert or not to divert: A retrospective analysis of variables that influence ileostomy omission in ileal pouch surgery
    Richard E Lovegrove
    St Mark s Hospital, Middlesex, UK
    Arch Surg 146:82-8. 2011
    ..A model could be developed to identify patients who can safely undergo restorative proctocolectomy (RPC) without proximal diversion...
  65. pmc Adjuvant radiotherapy is associated with increased sexual dysfunction in male patients undergoing resection for rectal cancer: a predictive model
    Alexander G Heriot
    The Department of Colorectal Surgery, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Ann Surg 242:502-10; discussion 510-1. 2005
    ....
  66. doi request reprint Quantification of risk of a positive (R1) resection margin following hepatic resection for metastatic colorectal cancer: an aid to clinical decision-making
    Fenella K S Welsh
    Department of Hepatobiliary Surgery, Basingstoke and North Hampshire Foundation Trust, Aldermaston Road, Basingstoke, Hampshire RG24 9NA, UK
    Surg Oncol 17:3-13. 2008
    ..This study aimed to develop a predictive index for quantifying the likelihood of a positive resection margin (R1) for patients undergoing hepatic resection for metastatic colorectal cancer...
  67. ncbi request reprint Prediction of postoperative mortality in elderly patients with colorectal cancer
    Alexander G Heriot
    Imperial College London, Department of Surgical Oncology and Tehnology, St Mary s Hospital, 10th Floor QEQM Wing, Praed Street, London, W2 1NY, United Kingdom
    Dis Colon Rectum 49:816-24. 2006
    ..This study was designed to develop a model for predicting postoperative mortality in elderly patients undergoing surgery for colorectal cancer...
  68. ncbi request reprint Assessment of operative risk in colorectal cancer surgery: the Cleveland Clinic Foundation colorectal cancer model
    Victor W Fazio
    Department of Colorectal Surgery, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Dis Colon Rectum 47:2015-24. 2004
    ..The purpose of the study was to describe the development of a dedicated prognostic index for quantifying operative risk in colorectal cancer surgery...
  69. ncbi request reprint Factors affecting circumferential resection margin involvement after rectal cancer excision
    Henry S Tilney
    Department of Biosurgery and Surgical Technology, Imperial College London, St Mary s Hospital, London, United Kingdom
    Dis Colon Rectum 50:29-36. 2007
    ....
  70. doi request reprint Multidisciplinary treatment of cancer of the rectum: a European approach
    R J Nicholls
    Department of Biosurgery and Surgical Technology, St Mary s Hospital, Imperial College, Praed St, London W2, UK
    Surg Oncol Clin N Am 17:533-51, viii. 2008
    ..In the United States, postoperative radiotherapy was preferred for many years. Advances were made through the use of randomized clinical trials, standardized restorative surgery, and more accurate preoperative staging by MRI...
  71. ncbi request reprint A meta-analysis of quality of life for abdominoperineal excision of rectum versus anterior resection for rectal cancer
    Julie A Cornish
    Department of Biosurgery and Surgical Technology, St Mary s Hospital, Imperial College, 10th Floor QEQM Wing, Praed Street, London, W2 1NY, UK
    Ann Surg Oncol 14:2056-68. 2007
    ..The aim of this study was to compare QoL following abdominoperineal excision of rectum (APER) with that after anterior resection (AR) in patients with rectal cancer...
  72. ncbi request reprint Evaluating operative risk in colorectal cancer surgery: ASA and POSSUM-based predictive models
    Samar Al-Homoud
    Department of Surgical Oncology and Technology, St Mary s Hospital, 10th Floor QEQM, Praed Street, London W2 1NY, UK
    Surg Oncol 13:83-92. 2004
    ....
  73. ncbi request reprint Evaluation of long-term survival after hepatic resection for metastatic colorectal cancer: a multifactorial model of 929 patients
    Myrddin Rees
    Department of Hepatobiliary Surgery, North Hampshire Hospital, Aldermaston Road, Basingstoke, Hampshire, United Kingdom
    Ann Surg 247:125-35. 2008
    ..To identify risk factors associated with cancer-specific survival and develop a predictive model for patients undergoing primary hepatic resection for metastatic colorectal cancer...
  74. ncbi request reprint A national perspective on the decline of abdominoperineal resection for rectal cancer
    Henry S Tilney
    Department of Biosurgery and Surgical Technology, Imperial College London, St Mary s Hospital, London, England
    Ann Surg 247:77-84. 2008
    ..To assess rates of abdominoperineal excision of the rectum (APER) for rectal cancer between centers and over time, and to evaluate the influence of patient characteristics, including social deprivation, on APER rate...
  75. pmc Evaluation of the learning curve in laparoscopic colorectal surgery: comparison of right-sided and left-sided resections
    Paris P Tekkis
    Department of Colorectal Surgery and the Minimally Invasive Surgery Center, Cleveland Clinic Foundation, Cleveland, OH, USA
    Ann Surg 242:83-91. 2005
    ..To provide a multidimensional analysis of the learning curve in major laparoscopic colonic and rectal surgery and compare outcomes between right-sided versus left-sided resections...
  76. ncbi request reprint POSSUM, p-POSSUM, and Cr-POSSUM: implementation issues in a United States health care system for prediction of outcome for colon cancer resection
    Anthony J Senagore
    Department of Colorectal Surgery, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Dis Colon Rectum 47:1435-41. 2004
    ..The aim of this study was to evaluate the applicability of these systems to a cohort of colon cancer patients undergoing surgery in the United States...
  77. ncbi request reprint Comparison of outcomes following ileostomy versus colostomy for defunctioning colorectal anastomoses
    Henry S Tilney
    Department of Biosurgery and Surgical Technology, Imperial College London, London, UK
    World J Surg 31:1142-51. 2007
    ..The present study evaluated outcomes of patients undergoing proximal diversion using either a loop ileostomy or loop colostomy following distal colorectal resection for malignant and non-malignant disease...
  78. ncbi request reprint Diagnostic precision of fecal calprotectin for inflammatory bowel disease and colorectal malignancy
    Alexander C von Roon
    Imperial College London, Department of Biosurgery and Surgical Technology, St Mary s Hospital, London, United Kingdom
    Am J Gastroenterol 102:803-13. 2007
    ..Using meta-analytical techniques, the study aimed to evaluate the diagnostic precision of FC for inflammatory bowel disease (IBD) and colorectal cancer (CRC) in adults and children...
  79. pmc Mortality control charts for comparing performance of surgical units: validation study using hospital mortality data
    Paris P Tekkis
    Academic Department of Surgery, King s College Hospital, London SE5 9RS
    BMJ 326:786-8. 2003
    ..To design and validate a statistical method for evaluating the performance of surgical units that adjusts for case volume and case mix...
  80. ncbi request reprint Met-analyses
    Paris P Tekkis
    Dis Colon Rectum 46:1019-20. 2003
  81. ncbi request reprint A meta-analysis comparing conventional end-to-end anastomosis vs. other anastomotic configurations after resection in Crohn's disease
    Constantinos Simillis
    Department of Biosurgery and Surgical Technology, Imperial College London, London, United Kingdom
    Dis Colon Rectum 50:1674-87. 2007
    ..This study compared outcomes between end-to-end anastomosis and other anastomotic configurations after intestinal resection for patients with Crohn's disease by using meta-analytical techniques...
  82. ncbi request reprint A meta-analysis comparing incidence of recurrence and indication for reoperation after surgery for perforating versus nonperforating Crohn's disease
    Constantinos Simillis
    Department of Surgical Oncology and Technology, Imperial College London, London, U K
    Am J Gastroenterol 103:196-205. 2008
    ....
  83. ncbi request reprint The United Kingdom National Bowel Cancer Project -- epidemiology and surgical risk in the elderly
    Emile Tan
    Imperial College, Department of Biosurgery and Surgical Technology, 10th Floor, QEQM, St Mary s Hospital, Praed Street, London W2 1NY, UK
    Eur J Cancer 43:2285-94. 2007
    ..To evaluate the epidemiology and risk of surgery in the treatment of colorectal cancer in the elderly...
  84. pmc Mortality and morbidity in gastro-oesophageal cancer surgery: initial results of ASCOT multicentre prospective cohort study
    Peter McCulloch
    Academic Unit of Surgery, University of Liverpool, University Hospital Aintree, Liverpool L9 7AL
    BMJ 327:1192-7. 2003
    ..To evaluate the effect of comorbidity and other risk factors on postoperative mortality and morbidity in patients undergoing major oesophageal and gastric surgery...
  85. pmc The Association of Coloproctology of Great Britain and Ireland study of large bowel obstruction caused by colorectal cancer
    Paris P Tekkis
    Department of Surgery, St Mark s Hospital, Harrow, UK
    Ann Surg 240:76-81. 2004
    ..This study was designed to investigate the early outcomes after surgical treatment of malignant large bowel obstruction (MBO) and to identify risk factors affecting operative mortality...
  86. ncbi request reprint The risk of cancer in patients with Crohn's disease
    Alexander C von Roon
    Department of Biosurgery and Surgical Technology, Imperial College, St Mary s Hospital, London, W2 1NY, UK
    Dis Colon Rectum 50:839-55. 2007
    ..The risk of cancer in patients with Crohn's disease is not well defined. Using meta-analytical techniques, the present study was designed to quantify the risk of intestinal, extraintestinal, and hemopoietic malignancies in such patients...
  87. ncbi request reprint Is rectal washout effective for preventing localized recurrence after anterior resection for rectal cancer?
    Vasilis A Constantinides
    Imperial College, Department of Biosurgery and Surgical Technology, St Mary s Hospital, 10th Floor QEQM Building, Imperial College, Praed Street, London, W2 1NY, United Kingdom
    Dis Colon Rectum 51:1339-44. 2008
    ..The present study evaluated the effect of rectal washout in reducing local recurrence after resection for rectal cancer...
  88. ncbi request reprint Safety and efficacy of strictureplasty for Crohn's disease: a systematic review and meta-analysis
    Takayuki Yamamoto
    Department of Colorectal Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Dis Colon Rectum 50:1968-86. 2007
    ..This study was designed to review safety and efficacy of strictureplasty for Crohn's disease...
  89. ncbi request reprint Meta-analysis of randomized studies evaluating chewing gum to enhance postoperative recovery following colectomy
    Sanjay Purkayastha
    Department of Biosurgery and Surgical Technology, Imperial College London, St Mary s Hospital, London, England
    Arch Surg 143:788-93. 2008
    ..To compare outcomes following abdominal surgery with or without the use of chewing gum in the early postoperative period...
  90. pmc Operative strategies for diverticular peritonitis: a decision analysis between primary resection and anastomosis versus Hartmann's procedures
    Vasilis A Constantinides
    Imperial College London, Department of Biosurgery and Surgical Technology, St Mary s Hospital London, UK
    Ann Surg 245:94-103. 2007
    ..To compare primary resection and anastomosis (PRA) with and without defunctioning stoma to Hartmann's procedure (HP) as the optimal operative strategy for patients presenting with Hinchey stage III-IV, perforated diverticulitis...
  91. ncbi request reprint The effect of Crohn's disease on outcomes after restorative proctocolectomy
    George E Reese
    Imperial College London, Department of Biosurgery and Surgical Technology, St Mary s Hospital, 10th Floor QEQM Building, Praed Street, London, UK
    Dis Colon Rectum 50:239-50. 2007
    ..This study was designed to compare postoperative adverse events and functional outcomes after ileal pouch-anal anastomosis between patients with Crohn's disease and those with non-Crohn's disease diagnoses...
  92. ncbi request reprint Fast-track failure after cardiac surgery: development of a prediction model
    Vasilis A Constantinides
    Imperial College London, Department of Surgical Oncology and Technology, St Mary s Hospital, London, UK
    Crit Care Med 34:2875-82. 2006
    ..The aim of this study was to determine risk factors for fast-track failure and incorporate them into a predictive fast-track failure score...
  93. ncbi request reprint Diagnostic precision of anti-Saccharomyces cerevisiae antibodies and perinuclear antineutrophil cytoplasmic antibodies in inflammatory bowel disease
    George E Reese
    Department of Biosurgery and Surgical Technology, Imperial College London, St Mary s Hospital, London, United Kingdom
    Am J Gastroenterol 101:2410-22. 2006
    ....
  94. ncbi request reprint Laparoscopic versus open hepatic resections for benign and malignant neoplasms--a meta-analysis
    Constantinos Simillis
    Imperial College London, Department of Surgical Oncology and Technology, St Mary s Hospital, London, United Kingdom
    Surgery 141:203-211. 2007
    ..The present study compared laparoscopic versus open surgery for patients with hepatic neoplasms with regard to short-term outcomes...
  95. ncbi request reprint The impact of technical factors on outcome of restorative proctocolectomy for familial adenomatous polyposis
    Alexander C von Roon
    Department of Biosurgery and Surgical Technology, Imperial College London, St Mary s Hospital, 10th Floor, QEQM Building, Praed Street, London, W2 1NY, United Kingdom
    Dis Colon Rectum 50:952-61. 2007
    ..This study was designed to assess the impact of technical factors on functional outcomes and complications in patients undergoing restorative proctocolectomy for familial adenomatous polyposis...
  96. ncbi request reprint Laparoscopic versus open surgery for rectal cancer: a meta-analysis
    Omer Aziz
    Department of Surgical Oncology and Technology, Imperial College London, St Mary s Hospital, 10th Floor QEQM Wing, Praed Street, London, W2 1NY, United Kingdom
    Ann Surg Oncol 13:413-24. 2006
    ..This study used meta-analytical techniques to compare laparoscopic and open surgery as the primary treatment for patients with rectal cancer with regard to short-term and long-term outcomes...
  97. ncbi request reprint Hartmann's reversal is associated with high postoperative adverse events
    H Nail Aydin
    Department of Colorectal Surgery, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Dis Colon Rectum 48:2117-26. 2005
    ..A comparison of postoperative outcomes is made be tween Hartmann's reversal and primary resection and anas tomosis...
  98. ncbi request reprint Primary resection with anastomosis vs. Hartmann's procedure in nonelective surgery for acute colonic diverticulitis: a systematic review
    Vasilis A Constantinides
    Imperial College of Science, Technology and Medicine, Department of Surgical Oncology and Technology, St Mary s Hospital, London, United Kingdom
    Dis Colon Rectum 49:966-81. 2006
    ..This study compares primary resection with anastomosis and Hartmann's procedure in an adult population with acute colonic diverticulitis...
  99. ncbi request reprint Functional renal outcome in on-pump and off-pump coronary revascularization: a propensity-based analysis
    Arjuna Weerasinghe
    Department of Cardiothoracic Surgery, St Mary s Hospital, London, United Kingdom
    Ann Thorac Surg 79:1577-83. 2005
    ..Renal adverse outcome was defined as minor (20% increase in serum creatinine from preoperative) or major (composite end point of postoperative serum creatinine >200 mumol/L or postoperative mechanical renal support)...
  100. ncbi request reprint Meta-analysis of clinical outcome after first and second liver resection for colorectal metastases
    Anthony Antoniou
    Imperial College London, Department of Biosurgery and Surgical Technology, St Mary s Hospital, London, UK
    Surgery 141:9-18. 2007
    ..The perioperative risk and long-term survival benefit of repeat hepatectomy for patients with liver metastases from colorectal cancer, compared with that of a first liver resection, has been reported with varying results in the literature...
  101. pmc Operative mortality in colorectal cancer: prospective national study
    Paris P Tekkis
    Department of Surgery, St Mark s Hospital, Harrow HA1 3UJ
    BMJ 327:1196-201. 2003
    ..To develop a mathematical model that will predict the probability of death after surgery for colorectal cancer...