Research Topics
Species | Paul R A StokesSummaryAffiliation: Imperial College Country: UK Publications
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Detail Information
Publications
Nature or nurture? Determining the heritability of human striatal dopamine function: an [18F]-DOPA PET studyPaul R A Stokes
Psychiatric Imaging Group, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital, London, UK
Neuropsychopharmacology 38:485-91. 2013....
History of cigarette smoking is associated with higher limbic GABAA receptor availabilityPaul R A Stokes
Centre for Neuropsychopharmacology, Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK
Neuroimage 69:70-7. 2013....
History of cannabis use is not associated with alterations in striatal dopamine D2/D3 receptor availabilityPaul R A Stokes
Psychiatric Imaging Group, MRC Clinical Sciences Centre, Imperial College London, London, UK
J Psychopharmacol 26:144-9. 2012..These findings suggest that, unlike other drugs of abuse, a history of cannabis use is not associated with alterations in striatal dopamine D(2)/D(3) receptor availability...
Can recreational doses of THC produce significant dopamine release in the human striatum?Paul R A Stokes
Psychiatry Group, MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital Campus, London, UK
Neuroimage 48:186-90. 2009..In animals, Delta9-tetrahydrocannabinol (THC) increases the rate of dopamine neuronal firing and release in the striatum. Thus cannabis use may increase dopamine release in the human striatum leading to vulnerability to psychosis...
Significant decreases in frontal and temporal [11C]-raclopride binding after THC challengePaul R A Stokes
MRC Clinical Science Centre, Imperial College, Hammersmith Hospital, London, UK
Neuroimage 52:1521-7. 2010..The interpretation of these findings in relation to prefrontal dopamine release is discussed...
The effects of the COMT Val108/158Met polymorphism on BOLD activation during working memory, planning, and response inhibition: a role for the posterior cingulate cortex?Paul R A Stokes
Psychiatry Group, MRC Clinical Science Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, London, UK
Neuropsychopharmacology 36:763-71. 2011....
Truth, lies or self-deception? Striatal D(2/3) receptor availability predicts individual differences in social conformityAlice Egerton
Institute of Psychiatry, King s College London, London, UK
Neuroimage 53:777-81. 2010..54 p=0.06) but not SDE (r=0.23, ns). Whilst these associations are modest, results suggest that striatal D(2/3) receptor availability may be particularly associated with social conformity, rather than self-deception...
Acute effect of the anti-addiction drug bupropion on extracellular dopamine concentrations in the human striatum: an [11C]raclopride PET studyAlice Egerton
Psychiatric Imaging, Medical Research Council Clinical Sciences Centre, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK
Neuroimage 50:260-6. 2010..These findings have important implications for understanding the mechanism of action underlying bupropions' therapeutic efficacy and for the development of novel treatments for addiction and depression...
