Paul R A Stokes
Affiliation: Imperial College
- Nature or nurture? Determining the heritability of human striatal dopamine function: an [18F]-DOPA PET studyPaul R A Stokes
Psychiatric Imaging Group, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital, London, UK
Neuropsychopharmacology 38:485-91. 2013....
- History of cigarette smoking is associated with higher limbic GABAA receptor availabilityPaul R A Stokes
Centre for Neuropsychopharmacology, Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK
Neuroimage 69:70-7. 2013....
- History of cannabis use is not associated with alterations in striatal dopamine D2/D3 receptor availabilityPaul R A Stokes
Psychiatric Imaging Group, MRC Clinical Sciences Centre, Imperial College London, London, UK
J Psychopharmacol 26:144-9. 2012..These findings suggest that, unlike other drugs of abuse, a history of cannabis use is not associated with alterations in striatal dopamine D(2)/D(3) receptor availability...
- Can recreational doses of THC produce significant dopamine release in the human striatum?Paul R A Stokes
Psychiatry Group, MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital Campus, London, UK
Neuroimage 48:186-90. 2009..In animals, Delta9-tetrahydrocannabinol (THC) increases the rate of dopamine neuronal firing and release in the striatum. Thus cannabis use may increase dopamine release in the human striatum leading to vulnerability to psychosis...
- Significant decreases in frontal and temporal [11C]-raclopride binding after THC challengePaul R A Stokes
MRC Clinical Science Centre, Imperial College, Hammersmith Hospital, London, UK
Neuroimage 52:1521-7. 2010..The interpretation of these findings in relation to prefrontal dopamine release is discussed...
- The effects of the COMT Val108/158Met polymorphism on BOLD activation during working memory, planning, and response inhibition: a role for the posterior cingulate cortex?Paul R A Stokes
Psychiatry Group, MRC Clinical Science Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, London, UK
Neuropsychopharmacology 36:763-71. 2011....
- Truth, lies or self-deception? Striatal D(2/3) receptor availability predicts individual differences in social conformityAlice Egerton
Institute of Psychiatry, King s College London, London, UK
Neuroimage 53:777-81. 2010..54 p=0.06) but not SDE (r=0.23, ns). Whilst these associations are modest, results suggest that striatal D(2/3) receptor availability may be particularly associated with social conformity, rather than self-deception...
- Acute effect of the anti-addiction drug bupropion on extracellular dopamine concentrations in the human striatum: an [11C]raclopride PET studyAlice Egerton
Psychiatric Imaging, Medical Research Council Clinical Sciences Centre, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK
Neuroimage 50:260-6. 2010..These findings have important implications for understanding the mechanism of action underlying bupropions' therapeutic efficacy and for the development of novel treatments for addiction and depression...