- Within-subject comparison of [(11)C]-(+)-PHNO and [(11)C]raclopride sensitivity to acute amphetamine challenge in healthy humansPaul Shotbolt
GlaxoSmithKline Clinical Imaging Centre, Hammersmith Hospital, London, UK
J Cereb Blood Flow Metab 32:127-36. 2012..This study indicates that [(11)C]-(+)-PHNO is superior to [(11)C]raclopride for studying acute fluctuations in synaptic dopamine in the human striatum. [(11)C]-(+)-PHNO also enables measurement of synaptic dopamine in D(3) regions...
- Relationships between deep brain stimulation and impulse control disorders in Parkinson's disease, with a literature reviewP Shotbolt
Department of Cognitive Neuropsychiatry, Institute of Psychiatry, London, UK
Parkinsonism Relat Disord 18:10-6. 2012..We recommend the routine pre-operative examination of patients for psychopathology and emphasize the importance of post-operative psychiatric surveillance...
- Striatal dopamine synthesis capacity in twins discordant for schizophreniaP Shotbolt
Psychiatric Imaging, MRC Clinical Sciences Centre, Hammersmith Hospital, Imperial College London, London, UK
Psychol Med 41:2331-8. 2011..Relatives of patients with schizophrenia are themselves at increased risk of developing the condition. In this study we examined striatal dopamine synthesis capacity in both members of twin pairs discordant for schizophrenia...