DAVID JAMES SHARP

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. pmc Distinct frontal systems for response inhibition, attentional capture, and error processing
    D J Sharp
    Division of Experimental Medicine, Imperial College London, London W12 0NN, United Kingdom
    Proc Natl Acad Sci U S A 107:6106-11. 2010
  2. pmc Regional changes in thalamic shape and volume with increasing age
    Emer J Hughes
    Imaging Sciences Department, MRC Clinical Sciences Centre, Hammersmith Hospital, Imperial College London, London W12 0NN, UK
    Neuroimage 63:1134-42. 2012
  3. pmc A robust method for investigating thalamic white matter tracts after traumatic brain injury
    Letizia Squarcina
    Department of Information Engineering, University of Padova, Via Gradenigo 6 b, 35131 Padova, Italy
    Neuroimage 63:779-88. 2012
  4. doi request reprint Investigating white matter injury after mild traumatic brain injury
    David J Sharp
    The Computational, Cognitive and Clinical Neuroimaging Laboratory, The Division of Experimental Medicine, The Centre for Neuroscience, Imperial College London, Hammersmith Hospital Campus, London, UK
    Curr Opin Neurol 24:558-63. 2011
  5. doi request reprint Default mode network functional and structural connectivity after traumatic brain injury
    David J Sharp
    The Hammersmith Hospital, London, W12 0NN, UK
    Brain 134:2233-47. 2011
  6. pmc White matter damage and cognitive impairment after traumatic brain injury
    Kirsi Maria Kinnunen
    Department of Psychology, Goldsmiths, University of London, London, UK
    Brain 134:449-63. 2011
  7. doi request reprint Increased frontoparietal integration after stroke and cognitive recovery
    David J Sharp
    Division of Neuroscience and Mental Health, Imperial College London, Hammersmith Hospital Campus, London, UK
    Ann Neurol 68:753-6. 2010
  8. doi request reprint The neural response to changing semantic and perceptual complexity during language processing
    David J Sharp
    Imperial College London, Hammersmith Hospital Campus, United Kingdom
    Hum Brain Mapp 31:365-77. 2010
  9. doi request reprint Fractionating the default mode network: distinct contributions of the ventral and dorsal posterior cingulate cortex to cognitive control
    Robert Leech
    Computational, Cognitive, and Clinical Neuroimaging Laboratory, Division of Experimental Medicine, Imperial College London, Hammersmith Hospital Campus, London W12 0NN, United Kingdom
    J Neurosci 31:3217-24. 2011
  10. ncbi request reprint Retrieving meaning after temporal lobe infarction: the role of the basal language area
    David J Sharp
    MRC Cyclotron Unit, Clinical Sciences Centre, Imperial College London, London, UK
    Ann Neurol 56:836-46. 2004

Collaborators

Detail Information

Publications13

  1. pmc Distinct frontal systems for response inhibition, attentional capture, and error processing
    D J Sharp
    Division of Experimental Medicine, Imperial College London, London W12 0NN, United Kingdom
    Proc Natl Acad Sci U S A 107:6106-11. 2010
    ..In keeping with work in nonhuman primates these findings demonstrate that successful motor inhibition is specifically associated with pre-SMA activation...
  2. pmc Regional changes in thalamic shape and volume with increasing age
    Emer J Hughes
    Imaging Sciences Department, MRC Clinical Sciences Centre, Hammersmith Hospital, Imperial College London, London W12 0NN, UK
    Neuroimage 63:1134-42. 2012
    ..These data suggest that atrophy of the frontal thalamo-cortical unit may explain, at least in part, disorders of attention, working memory and executive function associated with increasing age...
  3. pmc A robust method for investigating thalamic white matter tracts after traumatic brain injury
    Letizia Squarcina
    Department of Information Engineering, University of Padova, Via Gradenigo 6 b, 35131 Padova, Italy
    Neuroimage 63:779-88. 2012
    ....
  4. doi request reprint Investigating white matter injury after mild traumatic brain injury
    David J Sharp
    The Computational, Cognitive and Clinical Neuroimaging Laboratory, The Division of Experimental Medicine, The Centre for Neuroscience, Imperial College London, Hammersmith Hospital Campus, London, UK
    Curr Opin Neurol 24:558-63. 2011
    ..This is difficult to identify using conventional neuroimaging methods. We review recent work that uses advanced imaging methods to identify TAI following mild (m)TBI...
  5. doi request reprint Default mode network functional and structural connectivity after traumatic brain injury
    David J Sharp
    The Hammersmith Hospital, London, W12 0NN, UK
    Brain 134:2233-47. 2011
    ..They can be explained by two related changes: a compensatory increase in functional connectivity within the default mode network; and a variable degree of structural disconnection that modulates this change in network function...
  6. pmc White matter damage and cognitive impairment after traumatic brain injury
    Kirsi Maria Kinnunen
    Department of Psychology, Goldsmiths, University of London, London, UK
    Brain 134:449-63. 2011
    ....
  7. doi request reprint Increased frontoparietal integration after stroke and cognitive recovery
    David J Sharp
    Division of Neuroscience and Mental Health, Imperial College London, Hammersmith Hospital Campus, London, UK
    Ann Neurol 68:753-6. 2010
    ..This change reflects greater top-down control of speech comprehension and provides a mechanism by which language impairments after stroke may be compensated for...
  8. doi request reprint The neural response to changing semantic and perceptual complexity during language processing
    David J Sharp
    Imperial College London, Hammersmith Hospital Campus, United Kingdom
    Hum Brain Mapp 31:365-77. 2010
    ..These results demonstrate a flexible system for language processing, where activity within distinct parts of the network is modulated as processing demands change...
  9. doi request reprint Fractionating the default mode network: distinct contributions of the ventral and dorsal posterior cingulate cortex to cognitive control
    Robert Leech
    Computational, Cognitive, and Clinical Neuroimaging Laboratory, Division of Experimental Medicine, Imperial College London, Hammersmith Hospital Campus, London W12 0NN, United Kingdom
    J Neurosci 31:3217-24. 2011
    ....
  10. ncbi request reprint Retrieving meaning after temporal lobe infarction: the role of the basal language area
    David J Sharp
    MRC Cyclotron Unit, Clinical Sciences Centre, Imperial College London, London, UK
    Ann Neurol 56:836-46. 2004
    ..In addition, different profiles of response observed in each hemisphere suggest distinct contributions of both left and right inferior temporal cortices to the semantic processing of speech...
  11. ncbi request reprint Monitoring and the controlled processing of meaning: distinct prefrontal systems
    David J Sharp
    MRC Clinical Sciences Centre, Cyclotron Unit, Hammersmith Hospital, London W12 0NN, UK
    Cereb Cortex 14:1-10. 2004
    ..The function of these separate systems is integrated during the performance of verbal problem-solving tasks although they are differentially sensitive to stimulus degradation...
  12. ncbi request reprint The neural correlates of declining performance with age: evidence for age-related changes in cognitive control
    David J Sharp
    MRC Cyclotron Unit, Clinical Sciences Centre, Imperial College, London, UK
    Cereb Cortex 16:1739-49. 2006
    ..Thus, the ACC and lateral PFC show distinct responses to age-related decline in decision-making performance. This suggests that greater cognitive control is employed as individuals age and their performance declines...
  13. ncbi request reprint Lexical retrieval constrained by sound structure: the role of the left inferior frontal gyrus
    David J Sharp
    MRC Clinical Sciences Centre, Cyclotron Unit, Hammersmith Hospital, London W12 0NN, UK
    Brain Lang 92:309-19. 2005
    ..Within these regions there was greater activity for consonant WR, which is more difficult and imposes greater processing demands. These results support a process-specific organization of the anterior left IFG...