Affiliation: Imperial Cancer Research Fund
- Changing rates of adenocarcinoma and adenosquamous carcinoma of the cervix in EnglandP Sasieni
Department of Mathematics, Statistics, and Epidemiology, Imperial Cancer Research Fund, 61 Lincoln s Inn Fields, WC2A 3PX, London, UK
Lancet 357:1490-3. 2001..We have used additional data on cancers diagnosed in 1993-94 in England and up to 1997 in five English cancer registries to investigate more recent trends...
- Estimating prevalence when the true disease status is incompletely ascertainedP Sasieni
Department of Mathematics, Statistics and Epidemiology, Imperial Cancer Research Fund, 61 Lincoln s Inn Fields, London WC2A 3PX, UK
Stat Med 20:935-49. 2001..Estimation of and inference about the disease prevalence and the test sensitivity when disease status is ascertained on a random sample of those negative on both screening tests is discussed...
- Predicted impact of vaccination against human papillomavirus 16/18 on cancer incidence and cervical abnormalities in women aged 20-29 in the UKJ Cuzick
Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary University of London, Charterhouse Square, London, UK
Br J Cancer 102:933-9. 2010..In the UK, vaccination for girls aged 12-13 with catch-up for girls up to age 18 was introduced in 2008, using the bivalent GSK vaccine (Cervarix)...
- Review of cytology and histopathology as part of the NHS Cervical Screening Programme audit of invasive cervical cancersA Castanon
Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK
Cytopathology 23:13-22. 2012..To audit pathology slide reporting in the Cervical Screening Programme in England by reviewing cytology and histology slides from women subsequently diagnosed with invasive cervical cancer...
- A systematic review of the role of human papilloma virus (HPV) testing within a cervical screening programme: summary and conclusionsJ Cuzick
Department of Mathematics, Statistics and Epidemiology, Imperial Cancer Research Fund, London, UK
Br J Cancer 83:561-5. 2000..A range of issues including the age to start and stop screening, the appropriate screening interval, the role of self-sampling for HPV testing and the choice of primary test (HPV and/or cytology) require further evaluation...
- A surveillance model for skin cancer in organ transplant recipients: a 22-year prospective study in an ethnically diverse populationC A Harwood
Centre for Cutaneous Research, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, UK
Am J Transplant 13:119-29. 2013..This study provides a comprehensive, prospective analysis of skin cancer morbidity and risk in an ethnically diverse transplant population from which we derive an evidence-based skin cancer surveillance program...
- The association between naevi and melanoma in populations with different levels of sun exposure: a joint case-control study of melanoma in the UK and AustraliaV Bataille
Imperial Cancer Research Fund Skin Tumour Laboratory, London, UK
Br J Cancer 77:505-10. 1998....
- Photoadaptation to ultraviolet (UV) radiation in vivo: photoproducts in epidermal cells following UVB therapy for psoriasisV Bataille
Academic Department of Dermatology and ICRF Skin Tumour Laboratory, St Bartholomew s and Royal London School of Medicine and Dentistry, London E1 2AT, U K
Br J Dermatol 143:477-83. 2000..Psoriasis patients receiving long-term phototherapy are at an increased risk of non-melanoma skin cancers...
- Solar keratoses: a risk factor for melanoma but negative association with melanocytic naeviV Bataille
Dermatology Department, Royal London Hospital, UK
Int J Cancer 78:8-12. 1998..The fact that these 2 phenotypes were found to be negatively associated suggests that susceptibility to melanoma may be expressed via 2 distinct cutaneous phenotypes which may be genetically determined...
- Genetics of risk factors for melanoma: an adult twin study of nevi and frecklesV Bataille
Dermatology Department and Imperial Cancer Research Fund ICRF, Skin Tumour Laboratory, St Bartholomew s and Royal London School of Medicine, U K
J Natl Cancer Inst 92:457-63. 2000....
- APC in the regulation of intestinal crypt fissionH S Wasan
Cancer and Immunogenetics Laboratory, John Radcliffe Hospital, Headington, Oxford, U K
J Pathol 185:246-55. 1998..It is concluded that in vivo, the major defect in pre-neoplastic intestine harbouring APC mutations is elevated rates of crypt fission, and that this is also the mode by which micro-adenomas enlarge...
- Management of women who test positive for high-risk types of human papillomavirus: the HART studyJ Cuzick
Cancer Research UK, London, UK
Lancet 362:1871-6. 2003..We aimed to compare the detection rate and positive predictive values of HPV assay with cytology and to determine the best management strategy for HPV-positive women...
- Increased risk of skin cancer associated with the presence of epidermodysplasia verruciformis human papillomavirus types in normal skinC A Harwood
Centre for Cutaneous Research, St Bartholomew s and the Royal London School of Medicine and Dentistry, 2 Newark Street, London, E1 2AT, UK
Br J Dermatol 150:949-57. 2004..Human papillomaviruses (HPVs) are found in normal skin and in benign and malignant skin conditions. Epidermodysplasia verruciformis (EV) HPV types are those most plausibly linked to the development of squamous cell carcinomas of the skin...
- The influence of genetics and environmental factors in the pathogenesis of acne: a twin study of acne in womenV Bataille
Twin Research and Genetic Epidemiology Unit, St Thomas Hospital, London, UK
J Invest Dermatol 119:1317-22. 2002..The evidence of a major genetic influence on acne should stimulate the search for potential genes that may lead to new therapeutic approaches...
- Cancer incidence in the United Kingdom: projections to the year 2030M Mistry
Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, UK
Br J Cancer 105:1795-803. 2011..Projections of cancer incidence are important for planning health services and to provide a baseline for assessing the impact of public health interventions...
- A comprehensive study of chromosome 16q in invasive ductal and lobular breast carcinoma using array CGHR Roylance
Molecular and Population Genetics Laboratory, Cancer Research UK, Lincoln s Inn Fields, London, UK
Oncogene 25:6544-53. 2006..Higher-grade IDCs probably develop from low-grade lesions in most cases, but there remains evidence that some GII/GIII IDCs arise without a GI precursor...
- Evaluation of the UK breast screening programmesP Sasieni
Cancer Research UK Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventative Medicine, London, UK
Ann Oncol 14:1206-8. 2003..A new analysis of trends in England and Wales suggests that the effect of screening has been to reduce mortality by 8% over 10 years in those eligible for screening in 1990...
- Cancer screening for medical oncologists: importance of quality control and auditP Sasieni
Department of Mathematics, Statistics and Epidemiology, Cancer Research UK, London, UK
Ann Oncol 13:199-204. 2002
- Refining the Amsterdam Criteria and Bethesda Guidelines: testing algorithms for the prediction of mismatch repair mutation status in the familial cancer clinicL R Lipton
Molecular and Population Genetics Laboratory, London Institute, Cancer Research UK, 44 Lincoln's Inn Fields, London WC2A 3PX, United Kingdom
J Clin Oncol 22:4934-43. 2004..CONCLUSION: We believe that a quantitative model, such as the Amsterdam-plus model, should be the first choice for selecting families or patients for evaluation of HNPCC using molecular tests. We present an algorithm for this process...