A S Rice

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. ncbi Endocannabinoids and pain: spinal and peripheral analgesia in inflammation and neuropathy
    A S C Rice
    Department of Anaesthetics, Pain Research Group, Inperial College of Science, Technology and Medicine, Chelsea and Westminster Hospital Campus, 369 Fulham Road, London SW10 9NH, UK
    Prostaglandins Leukot Essent Fatty Acids 66:243-56. 2002
  2. ncbi Gabapentin in postherpetic neuralgia: a randomised, double blind, placebo controlled study
    A S Rice
    Pain Research Group, Department of Anaesthetics, Imperial College School of Medicine, Chelsea and Westminster Hospital Campus, 369 Fulham Road, London SW10 9NH, UK
    Pain 94:215-24. 2001
  3. ncbi Cannabinoids and pain
    A S Rice
    Imperial College School of Medicine, Department of Anaesthetics, London, UK
    Curr Opin Investig Drugs 2:399-414. 2001
  4. ncbi The anti-hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain
    S I Jaggar
    Department of Anaesthetics, Imperial College School of Medicine, St Mary s Hospital, London, UK
    Pain 76:189-99. 1998
  5. pmc The synthetic cannabinoid WIN55,212-2 attenuates hyperalgesia and allodynia in a rat model of neuropathic pain
    D Bridges
    Pain Research, Imperial College School of Medicine, Chelsea and Westminster Hospital Campus, London, SW10 9NH
    Br J Pharmacol 133:586-94. 2001
  6. ncbi The endogenous cannabinoid anandamide, but not the CB2 ligand palmitoylethanolamide, prevents the viscero-visceral hyper-reflexia associated with inflammation of the rat urinary bladder
    S I Jaggar
    Department of Anaesthetics, Imperial College School of Medicine, St Mary s Hospital, London, UK
    Neurosci Lett 253:123-6. 1998
  7. ncbi Role of the endogenous cannabinoid system in the formalin test of persistent pain in the rat
    P Beaulieu1
    Pain Research Group, Department of Anaesthetics, Imperial College School of Medicine, St Mary s Hospital Campus, Praed Street, W2 1NY, London, UK
    Eur J Pharmacol 396:85-92. 2000
  8. ncbi Administration of endocannabinoids prevents a referred hyperalgesia associated with inflammation of the urinary bladder
    W P Farquhar Smith
    Department of Anaesthetics, Imperial College School of Medicine, London, United Kingdom
    Anesthesiology 94:507-13; discussion 6A. 2001
  9. ncbi The capsaicin analogue SDZ249-665 attenuates the hyper-reflexia and referred hyperalgesia associated with inflammation of the rat urinary bladder
    S I Jaggar
    Pain Research, Department of Anaesthetics, Imperial College School of Medicine, St. Mary's Hospital Campus, Praed Street, London W2 1NY, UK
    Pain 89:229-35. 2001
  10. ncbi Localisation of cannabinoid receptor 1 in rat dorsal root ganglion using in situ hybridisation and immunohistochemistry
    D Bridges
    Pain Research, Department of Anaesthetics, Faculty of Medicine, Imperial College, Chelsea and Westminster Hospital Campus, London, UK
    Neuroscience 119:803-12. 2003

Collaborators

  • V Di Marzo
  • I Nagy
  • Pierre Beaulieu
  • D M Lambert
  • A H Dickenson
  • F S Hasnie
  • S I Jaggar
  • V C J Wallace
  • D Bridges
  • J Blackbeard
  • T Pheby
  • I J Lever
  • J W Brooks
  • W P Farquhar Smith
  • P Beaulieu1
  • K Hefner
  • I Lever
  • A Holmes
  • F Hasnie
  • T M Pheby
  • V Wallace
  • S Parker
  • J Breuer
  • S Vandevoorde
  • P R Kinchington
  • A R Segerdahl
  • S Sellaturay
  • M Malcangio
  • S W N Thompson
  • J Winter
  • G J Michael
  • M R Elphick
  • M Egertová
  • I F James
  • W P Farquhar-Smith
  • H C Scott
  • K Ahmad
  • S Punwar
  • T Bisogno1
  • G Ambrosino

Detail Information

Publications16

  1. ncbi Endocannabinoids and pain: spinal and peripheral analgesia in inflammation and neuropathy
    A S C Rice
    Department of Anaesthetics, Pain Research Group, Inperial College of Science, Technology and Medicine, Chelsea and Westminster Hospital Campus, 369 Fulham Road, London SW10 9NH, UK
    Prostaglandins Leukot Essent Fatty Acids 66:243-56. 2002
    ....
  2. ncbi Gabapentin in postherpetic neuralgia: a randomised, double blind, placebo controlled study
    A S Rice
    Pain Research Group, Department of Anaesthetics, Imperial College School of Medicine, Chelsea and Westminster Hospital Campus, 369 Fulham Road, London SW10 9NH, UK
    Pain 94:215-24. 2001
    ..The most common adverse events were dizziness and somnolence, particularly during the titration phase. Thus, this study confirms the role of gabapentin as an efficacious and well-tolerated treatment for postherpetic neuralgia...
  3. ncbi Cannabinoids and pain
    A S Rice
    Imperial College School of Medicine, Department of Anaesthetics, London, UK
    Curr Opin Investig Drugs 2:399-414. 2001
    ..Clinical trials are now required, but are hindered by a paucity of cannabinoids of suitable bioavailability and therapeutic ratio...
  4. ncbi The anti-hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain
    S I Jaggar
    Department of Anaesthetics, Imperial College School of Medicine, St Mary s Hospital, London, UK
    Pain 76:189-99. 1998
    ..This observation might be exploited to separate central psychotropic effects from peripheral analgesic actions of the cannabinoids, under inflammatory conditions...
  5. pmc The synthetic cannabinoid WIN55,212-2 attenuates hyperalgesia and allodynia in a rat model of neuropathic pain
    D Bridges
    Pain Research, Imperial College School of Medicine, Chelsea and Westminster Hospital Campus, London, SW10 9NH
    Br J Pharmacol 133:586-94. 2001
    ..These data indicate that cannabinoids may have therapeutic potential in neuropathic pain, and that this effect is mediated through the CB(1) receptor...
  6. ncbi The endogenous cannabinoid anandamide, but not the CB2 ligand palmitoylethanolamide, prevents the viscero-visceral hyper-reflexia associated with inflammation of the rat urinary bladder
    S I Jaggar
    Department of Anaesthetics, Imperial College School of Medicine, St Mary s Hospital, London, UK
    Neurosci Lett 253:123-6. 1998
    ..a). These findings provide further support for an acute anti-nociceptive and anti-hyperalgesic role for CB1 receptor agonists, with CB2 agonist effects only becoming important once the effects of inflammation are established...
  7. ncbi Role of the endogenous cannabinoid system in the formalin test of persistent pain in the rat
    P Beaulieu1
    Pain Research Group, Department of Anaesthetics, Imperial College School of Medicine, St Mary s Hospital Campus, Praed Street, W2 1NY, London, UK
    Eur J Pharmacol 396:85-92. 2000
    ..In conclusion, cannabinoid antagonists do not enhance formalin-evoked pain behaviour. These results suggest that, in this model, endogenous cannabinoids do not tonically attenuate inflammatory hyperalgesia...
  8. ncbi Administration of endocannabinoids prevents a referred hyperalgesia associated with inflammation of the urinary bladder
    W P Farquhar Smith
    Department of Anaesthetics, Imperial College School of Medicine, London, United Kingdom
    Anesthesiology 94:507-13; discussion 6A. 2001
    ..These data implicate cannabinoids as a novel treatment for vesical pain...
  9. ncbi The capsaicin analogue SDZ249-665 attenuates the hyper-reflexia and referred hyperalgesia associated with inflammation of the rat urinary bladder
    S I Jaggar
    Pain Research, Department of Anaesthetics, Imperial College School of Medicine, St. Mary's Hospital Campus, Praed Street, London W2 1NY, UK
    Pain 89:229-35. 2001
    ....
  10. ncbi Localisation of cannabinoid receptor 1 in rat dorsal root ganglion using in situ hybridisation and immunohistochemistry
    D Bridges
    Pain Research, Department of Anaesthetics, Faculty of Medicine, Imperial College, Chelsea and Westminster Hospital Campus, London, UK
    Neuroscience 119:803-12. 2003
    ..These findings suggest that whilst a wide range of DRG neuron phenotypes express CB(1), it is predominantly associated with myelinated fibres...
  11. ncbi [The pharmacology of cannabinoid derivatives: are there applications to treatment of pain?]
    P Beaulieu
    Département d Anesthésiologie, CHUM, Hotel Dieu, 3840 Saint Urbain, Montreal, Quebec, H2W 1T8, Canada
    Ann Fr Anesth Reanim 21:493-508. 2002
    ..To present the cannabinoid system together with recent findings on the pharmacology of these compounds in the treatment of pain...
  12. ncbi (S)-AMPA inhibits electrically evoked calcitonin gene-related peptide (CGRP) release from the rat dorsal horn: reversal by cannabinoid receptor antagonist SR141716A
    J W Brooks
    Pain Research Group, Department of Anaesthetics, Faculty of Medicine, Imperial College, London SW109NH, UK
    Neurosci Lett 372:85-8. 2004
    ..This study confirms that CGRP release from the dorsal horn is modulated via CB(1) activation. Furthermore a depolarising stimulus also modulates CGRP release, potentially via the release of endogenous cannabinoids...
  13. pmc Further characterization of a rat model of varicella zoster virus-associated pain: Relationship between mechanical hypersensitivity and anxiety-related behavior, and the influence of analgesic drugs
    F S Hasnie
    Pain Research Group, Department of Anaesthetics, Pain Medicine and Intensive Care, Faculty of Medicine, Imperial College Chelsea and Westminster Hospital Campus, 369 Fulham Road, London SW10 9NH, UK
    Neuroscience 144:1495-508. 2007
    ..This model will prove useful in elucidating the pathophysiology of zoster-associated pain and provide a tool for pre-clinical screening of analgesic drugs...
  14. pmc Continuous infusion of the cannabinoid WIN 55,212-2 to the site of a peripheral nerve injury reduces mechanical and cold hypersensitivity
    I J Lever
    Department of Anaesthetics, Intensive Care and Pain Medicine, Faculty of Medicine, Imperial College London, Chelsea and Westminster Hospital Campus, London, UK
    Br J Pharmacol 151:292-302. 2007
    ..Restricting cannabinoid delivery to peripheral tissues at systemically inactive doses offers a potential solution to this problem...
  15. pmc Mechanical and cold hypersensitivity in nerve-injured C57BL/6J mice is not associated with fear-avoidance- and depression-related behaviour
    F S Hasnie
    Pain Research Group, Department of Anaesthetics, Imperial College London, UK
    Br J Anaesth 98:816-22. 2007
    ..To improve the clinical validity of a widely used rodent model of traumatic peripheral neuropathy, we have investigated fear-avoidance- and depression-related behaviours in nerve-injured and sham-operated mice over a 4 week period...
  16. pmc The effect of the palmitoylethanolamide analogue, palmitoylallylamide (L-29) on pain behaviour in rodent models of neuropathy
    V C J Wallace
    Pain Research Group, Department of Anaesthetics, Pain Medicine and Intensive Care, Faculty of Medicine, Imperial College London, Chelsea and Westminster Hospital Campus, 369 Fulham Road, London, UK
    Br J Pharmacol 151:1117-28. 2007
    ....