Nicolas Regamey

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. ncbi request reprint Isolation of human bocavirus from Swiss infants with respiratory infections
    Nicolas Regamey
    Pediatric Respiratory Medicine, University Children s Hospital of Berne, Berne, Switzerland
    Pediatr Infect Dis J 26:177-9. 2007
  2. doi request reprint Increased airway smooth muscle mass in children with asthma, cystic fibrosis, and non-cystic fibrosis bronchiectasis
    Nicolas Regamey
    Department of Gene Therapy, National Heart and Lung Institute, 1B Manresa Road, London SW3 6LR, UK
    Am J Respir Crit Care Med 177:837-43. 2008
  3. ncbi request reprint Quality, size, and composition of pediatric endobronchial biopsies in cystic fibrosis
    Nicolas Regamey
    Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK
    Chest 131:1710-7. 2007
  4. doi request reprint Viral etiology of acute respiratory infections with cough in infancy: a community-based birth cohort study
    Nicolas Regamey
    Pediatric Respiratory Medicine, University Children s Hospital of Berne, Berne, Switzerland
    Pediatr Infect Dis J 27:100-5. 2008
  5. doi request reprint Distinct patterns of inflammation in the airway lumen and bronchial mucosa of children with cystic fibrosis
    Nicolas Regamey
    Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK
    Thorax 67:164-70. 2012
  6. doi request reprint Sputum inflammatory phenotypes are not stable in children with asthma
    Louise Fleming
    Department of Respiratory Paediatrics, Royal Brompton Hospital, Southwood Lane, London, UK
    Thorax 67:675-81. 2012
  7. pmc Pediatric severe asthma is characterized by eosinophilia and remodeling without T(H)2 cytokines
    Cara J Bossley
    The Royal Brompton and Harefield NHS Trust, London, UK
    J Allergy Clin Immunol 129:974-82.e13. 2012
  8. pmc Airway remodelling in children with cystic fibrosis
    Tom N Hilliard
    Department of Gene Therapy, National Heart and Lung Institute, Imperial College, London, UK
    Thorax 62:1074-80. 2007
  9. doi request reprint Quantification of periciliary fluid height in human airway biopsies is feasible, but not suitable as a biomarker
    Uta Griesenbach
    Department of Gene Therapy, Imperial College London, UK
    Am J Respir Cell Mol Biol 44:309-15. 2011
  10. pmc The Th17 pathway in cystic fibrosis lung disease
    Hui Leng Tan
    Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK
    Am J Respir Crit Care Med 184:252-8. 2011

Detail Information

Publications15

  1. ncbi request reprint Isolation of human bocavirus from Swiss infants with respiratory infections
    Nicolas Regamey
    Pediatric Respiratory Medicine, University Children s Hospital of Berne, Berne, Switzerland
    Pediatr Infect Dis J 26:177-9. 2007
    ..HBoV was identified in 5 (4.5%) of 112 infants as young as 3 months of age. In 4 of the 5 infants, HBoV was associated with other respiratory viruses. We conclude that HBoV circulates in the community and is acquired early in life...
  2. doi request reprint Increased airway smooth muscle mass in children with asthma, cystic fibrosis, and non-cystic fibrosis bronchiectasis
    Nicolas Regamey
    Department of Gene Therapy, National Heart and Lung Institute, 1B Manresa Road, London SW3 6LR, UK
    Am J Respir Crit Care Med 177:837-43. 2008
    ..Structural alterations to airway smooth muscle (ASM) are a feature of asthma and cystic fibrosis (CF) in adults...
  3. ncbi request reprint Quality, size, and composition of pediatric endobronchial biopsies in cystic fibrosis
    Nicolas Regamey
    Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK
    Chest 131:1710-7. 2007
    ..We prospectively assessed how the quality of biopsy specimens obtained from children with CF compare with those from children with other airway diseases...
  4. doi request reprint Viral etiology of acute respiratory infections with cough in infancy: a community-based birth cohort study
    Nicolas Regamey
    Pediatric Respiratory Medicine, University Children s Hospital of Berne, Berne, Switzerland
    Pediatr Infect Dis J 27:100-5. 2008
    ....
  5. doi request reprint Distinct patterns of inflammation in the airway lumen and bronchial mucosa of children with cystic fibrosis
    Nicolas Regamey
    Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK
    Thorax 67:164-70. 2012
    ..Studies in cystic fibrosis (CF) generally focus on inflammation present in the airway lumen. Little is known about inflammation occurring in the airway wall, the site ultimately destroyed in end-stage disease...
  6. doi request reprint Sputum inflammatory phenotypes are not stable in children with asthma
    Louise Fleming
    Department of Respiratory Paediatrics, Royal Brompton Hospital, Southwood Lane, London, UK
    Thorax 67:675-81. 2012
    ..Treatment strategies based on these phenotypes have been successful. This study evaluated sputum cytology in children with asthma to classify sputum inflammatory phenotypes and to assess their stability over time...
  7. pmc Pediatric severe asthma is characterized by eosinophilia and remodeling without T(H)2 cytokines
    Cara J Bossley
    The Royal Brompton and Harefield NHS Trust, London, UK
    J Allergy Clin Immunol 129:974-82.e13. 2012
    ..The pathology of pediatric severe therapy-resistant asthma (STRA) is little understood...
  8. pmc Airway remodelling in children with cystic fibrosis
    Tom N Hilliard
    Department of Gene Therapy, National Heart and Lung Institute, Imperial College, London, UK
    Thorax 62:1074-80. 2007
    ..A study was undertaken to determine changes in airway remodelling in children with CF compared with appropriate disease and healthy controls...
  9. doi request reprint Quantification of periciliary fluid height in human airway biopsies is feasible, but not suitable as a biomarker
    Uta Griesenbach
    Department of Gene Therapy, Imperial College London, UK
    Am J Respir Cell Mol Biol 44:309-15. 2011
    ..quot; However, power calculations indicate that this assay can only be considered as a biomarker in large, late-phase clinical trials, because sample sizes required to achieve sufficient power are comparatively large...
  10. pmc The Th17 pathway in cystic fibrosis lung disease
    Hui Leng Tan
    Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK
    Am J Respir Crit Care Med 184:252-8. 2011
    ..Cystic fibrosis (CF) is characterized by bronchoalveolar neutrophilia and submucosal lymphocytosis. We hypothesized that Th17 lymphocytes are part of this submucosal infiltrate...
  11. doi request reprint Time required to obtain endobronchial biopsies in children during fiberoptic bronchoscopy
    Nicolas Regamey
    Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, United Kingdom
    Pediatr Pulmonol 44:76-9. 2009
    ..Endobronchial biopsies are an important tool for the study of airway remodeling in children. We aimed to evaluate the impact of performing endobronchial biopsies as a part of fiberoptic bronchoscopy on the length of the procedure...
  12. doi request reprint Use of sputum eosinophil counts to guide management in children with severe asthma
    Louise Fleming
    National Heart and Lung Institute, Respiratory Paediatrics, Imperial College, London, UK
    Thorax 67:193-8. 2012
    ..A study was undertaken to investigate whether this strategy would be successful in children with severe asthma...
  13. doi request reprint Endobronchial biopsy in childhood
    Nicolas Regamey
    Chest 133:312; author reply 313. 2008
  14. ncbi request reprint Airway epithelial IL-15 transforms monocytes into dendritic cells
    Nicolas Regamey
    Division of Respiratory Medicine, University Hospital of Berne, Freiburgstrasse 15, CH 3010 Berne, Switzerland
    Am J Respir Cell Mol Biol 37:75-84. 2007
    ..Thus, our results demonstrate that airway epithelial cell-conditioned media have the capacity to differentiate monocytes into functional DCs, a process substantially mediated by epithelial-derived IL-15...
  15. ncbi request reprint Human coronavirus NL63 associated with lower respiratory tract symptoms in early life
    Laurent Kaiser
    Central Laboratory of Virology, Division of Infectious Diseases, University Hospitals of Geneva, Geneva, Switzerland
    Pediatr Infect Dis J 24:1015-7. 2005
    ..NL63 was recovered at the onset of symptoms and was cleared within 3 weeks in half of the cases. Our data suggests that coronavirus NL63 causes lower respiratory tract symptoms and is acquired in early life...