Anna M Randi

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. doi request reprint Regulation of angiogenesis by ETS transcription factors
    Anna M Randi
    National Heart and Lung Institute NHLI Cardiovascular Sciences Unit, Hammersmith Hospital, Imperial College London, London W12 0NN, UK
    Biochem Soc Trans 37:1248-53. 2009
  2. doi request reprint ICAM-2 regulates vascular permeability and N-cadherin localization through ezrin-radixin-moesin (ERM) proteins and Rac-1 signalling
    Valerie Amsellem
    Imperial College for Translational and Experimental Medicine, NHLI Vascular Sciences, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12, Onn, UK
    Cell Commun Signal 12:12. 2014
  3. pmc Transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin
    Graeme M Birdsey
    National Heart and Lung Institute Cardiovascular Sciences Unit, Hammersmith Hospital, Imperial College London, UK
    Blood 111:3498-506. 2008
  4. pmc The transcription factor Erg controls endothelial cell quiescence by repressing activity of nuclear factor (NF)-κB p65
    Nicola H Dryden
    National Heart and Lung Institute Cardiovascular Sciences Unit, Hammersmith Hospital, Imperial College London, London W12 0NN, UK
    J Biol Chem 287:12331-42. 2012
  5. doi request reprint The transcription factor Erg inhibits vascular inflammation by repressing NF-kappaB activation and proinflammatory gene expression in endothelial cells
    Andrea Sperone
    Imperial College London, Hammersmith Hospital, London W12 0NN, England
    Arterioscler Thromb Vasc Biol 31:142-50. 2011
  6. doi request reprint Cytoprotective signaling and gene expression in endothelial cells and macrophages-lessons for atherosclerosis
    Dorian O Haskard
    Vascular Science Section, National Heart and Lung Institute, Imperial College, Hammersmith Hospital, London W12 ONN, UK
    Microcirculation 20:203-16. 2013
  7. ncbi request reprint Endothelial intercellular adhesion molecule (ICAM)-2 regulates angiogenesis
    Miao Tzu Huang
    Imperial College, BHF Cardiovascular Sciences Unit, Hammersmith Hospital, Du Cane Road, London W12 0NN, United Kingdom
    Blood 106:1636-43. 2005
  8. doi request reprint PPARdelta and PGC1alpha act cooperatively to induce haem oxygenase-1 and enhance vascular endothelial cell resistance to stress
    Faisal Ali
    Bywaters Center for Vascular Inflammation, Cardiovascular Sciences, National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 ONN, UK
    Cardiovasc Res 85:701-10. 2010
  9. ncbi request reprint Aprotinin inhibits proinflammatory activation of endothelial cells by thrombin through the protease-activated receptor 1
    Jonathan R S Day
    Eric Bywaters Centre, Imperial College London, Faculty of Medicine, Hammersmith Hospital, London, United Kingdom
    J Thorac Cardiovasc Surg 131:21-7. 2006
  10. ncbi request reprint Protein kinase Cε activity induces anti-inflammatory and anti-apoptotic genes via an ERK1/2- and NF-κB-dependent pathway to enhance vascular protection
    Odile Dumont
    Vascular Sciences Unit, Imperial Centre for Translational and Experimental Medicine, National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, London, UK
    Biochem J 447:193-204. 2012

Collaborators

Detail Information

Publications13

  1. doi request reprint Regulation of angiogenesis by ETS transcription factors
    Anna M Randi
    National Heart and Lung Institute NHLI Cardiovascular Sciences Unit, Hammersmith Hospital, Imperial College London, London W12 0NN, UK
    Biochem Soc Trans 37:1248-53. 2009
    ..Finally, we discuss novel evidence that shows how these transcription factors act in a combinatorial fashion with others, through composite sites that may be crucial in determining endothelial specificity in gene transcription...
  2. doi request reprint ICAM-2 regulates vascular permeability and N-cadherin localization through ezrin-radixin-moesin (ERM) proteins and Rac-1 signalling
    Valerie Amsellem
    Imperial College for Translational and Experimental Medicine, NHLI Vascular Sciences, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12, Onn, UK
    Cell Commun Signal 12:12. 2014
    ..Both cadherins are required for vascular development. The intercellular adhesion molecule (ICAM)-2, also localized at endothelial junctions, is involved in leukocyte recruitment and angiogenesis...
  3. pmc Transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin
    Graeme M Birdsey
    National Heart and Lung Institute Cardiovascular Sciences Unit, Hammersmith Hospital, Imperial College London, UK
    Blood 111:3498-506. 2008
    ..These results identify a new pathway regulating angiogenesis and endothelial survival, via the transcription factor Erg and the adhesion molecule VE-cadherin...
  4. pmc The transcription factor Erg controls endothelial cell quiescence by repressing activity of nuclear factor (NF)-κB p65
    Nicola H Dryden
    National Heart and Lung Institute Cardiovascular Sciences Unit, Hammersmith Hospital, Imperial College London, London W12 0NN, UK
    J Biol Chem 287:12331-42. 2012
    ..These results identify a role for Erg as a gatekeeper controlling vascular inflammation, thus providing an important barrier to protect against inappropriate endothelial activation...
  5. doi request reprint The transcription factor Erg inhibits vascular inflammation by repressing NF-kappaB activation and proinflammatory gene expression in endothelial cells
    Andrea Sperone
    Imperial College London, Hammersmith Hospital, London W12 0NN, England
    Arterioscler Thromb Vasc Biol 31:142-50. 2011
    ..To test whether ETS-related gene (Erg) inhibits tumor necrosis factor (TNF)-α-dependent endothelial activation and inflammation...
  6. doi request reprint Cytoprotective signaling and gene expression in endothelial cells and macrophages-lessons for atherosclerosis
    Dorian O Haskard
    Vascular Science Section, National Heart and Lung Institute, Imperial College, Hammersmith Hospital, London W12 ONN, UK
    Microcirculation 20:203-16. 2013
    ....
  7. ncbi request reprint Endothelial intercellular adhesion molecule (ICAM)-2 regulates angiogenesis
    Miao Tzu Huang
    Imperial College, BHF Cardiovascular Sciences Unit, Hammersmith Hospital, Du Cane Road, London W12 0NN, United Kingdom
    Blood 106:1636-43. 2005
    ..Our findings identify a novel pathway regulating angiogenesis through ICAM-2 and a novel mechanism for Rac activation during angiogenesis...
  8. doi request reprint PPARdelta and PGC1alpha act cooperatively to induce haem oxygenase-1 and enhance vascular endothelial cell resistance to stress
    Faisal Ali
    Bywaters Center for Vascular Inflammation, Cardiovascular Sciences, National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 ONN, UK
    Cardiovasc Res 85:701-10. 2010
    ..We investigated the role of PPARdelta and its co-activator, PPARgamma co-activator 1alpha (PGC1alpha), in vasculoprotection against oxidant-induced injury via induction of haem oxygenase-1...
  9. ncbi request reprint Aprotinin inhibits proinflammatory activation of endothelial cells by thrombin through the protease-activated receptor 1
    Jonathan R S Day
    Eric Bywaters Centre, Imperial College London, Faculty of Medicine, Hammersmith Hospital, London, United Kingdom
    J Thorac Cardiovasc Surg 131:21-7. 2006
    ..Here we have examined whether aprotinin inhibits endothelial protease-activated receptor 1 activation and resulting proinflammatory responses induced by thrombin...
  10. ncbi request reprint Protein kinase Cε activity induces anti-inflammatory and anti-apoptotic genes via an ERK1/2- and NF-κB-dependent pathway to enhance vascular protection
    Odile Dumont
    Vascular Sciences Unit, Imperial Centre for Translational and Experimental Medicine, National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, London, UK
    Biochem J 447:193-204. 2012
    ....
  11. pmc Endothelial von Willebrand factor regulates angiogenesis
    Richard D Starke
    Cardiovascular Sciences, National Heart and Lung Institute, Faculty of Medicine, Hammersmith Campus, Imperial College Academic Health Sciences Centre, Imperial College London, London, UK
    Blood 117:1071-80. 2011
    ..These results may have important consequences for the management of VWD, with potential therapeutic implications for vascular diseases...
  12. doi request reprint Dysfunction of endothelial progenitor cells from smokers and chronic obstructive pulmonary disease patients due to increased DNA damage and senescence
    Koralia E Paschalaki
    Airway Disease Section and National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom Vascular Sciences, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom Histology Embryology Department, Faculty of Medicine, University of Athens, Athens, Greece
    Stem Cells 31:2813-26. 2013
    ..These defects may contribute to vascular disease and cardiovascular events in smokers and could therefore constitute therapeutic targets for intervention. Stem Cells 2013;31:2813-2826. ..
  13. ncbi request reprint Statin-induced expression of decay-accelerating factor protects vascular endothelium against complement-mediated injury
    Justin C Mason
    British Heart Foundation Cardiovascular Medicine Unit, National Heart and Lung Institute, Imperial College, Hammersmith Hospital, London, UK
    Circ Res 91:696-703. 2002
    ..Modulation of complement regulatory protein expression may contribute to the early beneficial effects of statins in reducing the morbidity and mortality associated with atherosclerosis...