Ruth Peters

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. ncbi Kidney function in the very elderly with hypertension: data from the hypertension in the very elderly (HYVET) trial
    Ruth Peters
    Imperial College London, London, UK
    Age Ageing 42:253-8. 2013
  2. doi Impact of transiently elevated diastolic pressure on cause of death: 29-year follow-up from the General Practice Hypertension Study Group
    Ruth Peters
    Imperial College London, London, UK
    J Hypertens 31:71-6. 2013
  3. doi Blood pressure, smoking and alcohol use, association with vascular dementia
    Ruth Peters
    Imperial Clinical Trials Unit, School of Public Health, St Mary s Campus, London W2 1PG, USA
    Exp Gerontol 47:865-72. 2012
  4. doi The prevention of dementia
    Ruth Peters
    Imperial College Faculty of Medicine, Hammersmith Campus, London, UK
    Int J Geriatr Psychiatry 24:452-8. 2009
  5. pmc Smoking, dementia and cognitive decline in the elderly, a systematic review
    Ruth Peters
    Experimental Medicine and Toxicology Imperial College Faculty of Medicine, Hammersmith Campus, Du Cane Road, London, UK
    BMC Geriatr 8:36. 2008
  6. doi Vascular risk factors and cognitive function among 3763 participants in the Hypertension in the Very Elderly Trial (HYVET): a cross-sectional analysis
    Ruth Peters
    Care of the Elderly, Imperial College Faculty of Medicine, London, U K
    Int Psychogeriatr 21:359-68. 2009
  7. doi Sociodemographic and lifestyle risk factors for incident dementia and cognitive decline in the HYVET
    Ruth Peters
    Care of the Elderly, Faculty of Medicine, Imperial College London, W12 0NN, UK
    Age Ageing 38:521-7. 2009
  8. ncbi Hypertension, dementia, and antihypertensive treatment: implications for the very elderly
    Ruth Peters
    Faculty of Medicine, Imperial College London, Exhibition Road, London W120NN, United Kingdom
    Curr Hypertens Rep 11:277-82. 2009
  9. doi Cardiovascular and biochemical risk factors for incident dementia in the Hypertension in the Very Elderly Trial
    Ruth Peters
    Care of the Elderly Imperial College, Du Cane Rd London W12 0NN, UK
    J Hypertens 27:2055-62. 2009
  10. ncbi Association of depression with subsequent mortality, cardiovascular morbidity and incident dementia in people aged 80 and over and suffering from hypertension. Data from the Hypertension in the Very Elderly Trial (HYVET)
    Ruth Peters
    Imperial College London, UK
    Age Ageing 39:439-45. 2010

Collaborators

Detail Information

Publications32

  1. ncbi Kidney function in the very elderly with hypertension: data from the hypertension in the very elderly (HYVET) trial
    Ruth Peters
    Imperial College London, London, UK
    Age Ageing 42:253-8. 2013
    ..numerous reports have linked impaired kidney function to a higher risk of cardiovascular events and mortality. There are relatively few data relating to kidney function in the very elderly...
  2. doi Impact of transiently elevated diastolic pressure on cause of death: 29-year follow-up from the General Practice Hypertension Study Group
    Ruth Peters
    Imperial College London, London, UK
    J Hypertens 31:71-6. 2013
    ..The emphasis has shifted over time from diastolic pressure to systolic pressure and variability in blood pressure. This study examined the impact of transient and sustained diastolic hypertension on later mortality...
  3. doi Blood pressure, smoking and alcohol use, association with vascular dementia
    Ruth Peters
    Imperial Clinical Trials Unit, School of Public Health, St Mary s Campus, London W2 1PG, USA
    Exp Gerontol 47:865-72. 2012
    ..This review will concentrate on the prevention of dementia and attempt to provide an overview of the evidence relating to vascular related dementia and the potential risk factors of hypertension, alcohol use and smoking behaviour...
  4. doi The prevention of dementia
    Ruth Peters
    Imperial College Faculty of Medicine, Hammersmith Campus, London, UK
    Int J Geriatr Psychiatry 24:452-8. 2009
    ..Dementia is prevalent in older adults and the population is ageing. Many factors have been associated with dementia and anything that may aid the prevention of dementia is of importance...
  5. pmc Smoking, dementia and cognitive decline in the elderly, a systematic review
    Ruth Peters
    Experimental Medicine and Toxicology Imperial College Faculty of Medicine, Hammersmith Campus, Du Cane Road, London, UK
    BMC Geriatr 8:36. 2008
    ..Cardiovascular risk factors have been linked to increased risk of dementia. A previous meta-analysis found that current smokers were at higher risk of subsequent dementia, Alzheimer's disease, vascular dementia and cognitive decline...
  6. doi Vascular risk factors and cognitive function among 3763 participants in the Hypertension in the Very Elderly Trial (HYVET): a cross-sectional analysis
    Ruth Peters
    Care of the Elderly, Imperial College Faculty of Medicine, London, U K
    Int Psychogeriatr 21:359-68. 2009
    ..It is well known that the global population is aging and that those over the age of 80 are the fastest growing part of this expansion. Also known is that prevalence of hypertension and cognitive decline both increase with increasing age...
  7. doi Sociodemographic and lifestyle risk factors for incident dementia and cognitive decline in the HYVET
    Ruth Peters
    Care of the Elderly, Faculty of Medicine, Imperial College London, W12 0NN, UK
    Age Ageing 38:521-7. 2009
    ..Dementia risk also increases with age and is thought to be higher in hypertensives...
  8. ncbi Hypertension, dementia, and antihypertensive treatment: implications for the very elderly
    Ruth Peters
    Faculty of Medicine, Imperial College London, Exhibition Road, London W120NN, United Kingdom
    Curr Hypertens Rep 11:277-82. 2009
    ..Meta-analyses used to explore this area further are inconclusive, and comparative trials are now required...
  9. doi Cardiovascular and biochemical risk factors for incident dementia in the Hypertension in the Very Elderly Trial
    Ruth Peters
    Care of the Elderly Imperial College, Du Cane Rd London W12 0NN, UK
    J Hypertens 27:2055-62. 2009
    ..The aim of these analyses was to examine the impact of baseline cardiovascular and biochemical factors upon incident dementia and cognitive decline in a very elderly hypertensive group...
  10. ncbi Association of depression with subsequent mortality, cardiovascular morbidity and incident dementia in people aged 80 and over and suffering from hypertension. Data from the Hypertension in the Very Elderly Trial (HYVET)
    Ruth Peters
    Imperial College London, UK
    Age Ageing 39:439-45. 2010
    ..depression is common in elderly people and may be associated with increased cardiovascular risk and incident dementia...
  11. ncbi The effect of treatment based on a diuretic (indapamide) +/- ACE inhibitor (perindopril) on fractures in the Hypertension in the Very Elderly Trial (HYVET)
    Ruth Peters
    Imperial College Faculty of Medicine, Hammersmith Campus Du Cane Road, London UK
    Age Ageing 39:609-16. 2010
    ..fractures may have serious implications in an elderly individual, and fracture prevention may include a careful choice of medications...
  12. pmc Modelling cognitive decline in the Hypertension in the Very Elderly Trial [HYVET] and proposed risk tables for population use
    Ruth Peters
    Imperial Clinical Trials Unit, Imperial College London, London, United Kingdom
    PLoS ONE 5:e11775. 2010
    ..Here, we modelled dynamics of cognition in relation to the treatment of hypertension, to see if treatment effects might better be discerned by a model that included baseline measures of cognition and consequent mortality..
  13. doi Predictive value of the Clock Drawing Test. A review of the literature
    Ruth Peters
    Care of the Elderly, Imperial College Faculty of Medicine, Hammersmith Campus, London, UK
    Dement Geriatr Cogn Disord 26:351-5. 2008
    ..The Clock Drawing Test (CDT) assesses cognition focusing on executive function and praxis in contrast to the more language-based Mini-Mental State Exam. The CDT may allow early identification of cognitive decline...
  14. pmc Haemoglobin, anaemia, dementia and cognitive decline in the elderly, a systematic review
    Ruth Peters
    Experimental Medicine and Toxicology, Imperial College Faculty of Medicine, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK
    BMC Geriatr 8:18. 2008
    ..The elderly are more at risk of developing dementia and are also more likely to suffer from anaemia, although there is relatively little longitudinal literature addressing this association...
  15. pmc Ageing and the brain
    R Peters
    Care of the Elderly, Imperial College Faculty of Medicine, Hammersmith Campus, Du Cane Road, London W12 0NN, UK
    Postgrad Med J 82:84-8. 2006
    ..A healthy life both physically and mentally may be the best defence against the changes of an ageing brain. Additional measures to prevent cardiovascular disease may also be important...
  16. ncbi A substudy protocol of the hypertension in the Very Elderly Trial assessing cognitive decline and dementia incidence (HYVET-COG) : An ongoing randomised, double-blind, placebo-controlled trial
    Ruth Peters
    Imperial College School of Medicine, Section of Elderly Care, Hammersmith Hospital, London, UK
    Drugs Aging 23:83-92. 2006
    ..The objective of this protocol is to determine whether treatment of hypertension in this very elderly group affects the incidence of dementia and decline in cognitive function during the period of the HYVET trial...
  17. ncbi Alcohol, dementia and cognitive decline in the elderly: a systematic review
    Ruth Peters
    Imperial College, London, UK
    Age Ageing 37:505-12. 2008
    ..Alcohol has known negative effects in large quantities but may be protective for the cardiovascular system in smaller amounts. Effect of alcohol intake may be greater in the elderly and may impact on cognition...
  18. ncbi Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo controlled trial
    Ruth Peters
    Care of the Elderly, Imperial College London, London, UK
    Lancet Neurol 7:683-9. 2008
    ..The Hypertension in the Very Elderly trial (HYVET) was designed to assess the risks and benefits of treatment of hypertension in elderly patients and included an assessment of cognitive function...
  19. ncbi Increased pulse pressure linked to dementia: further results from the Hypertension in the Very Elderly Trial - HYVET
    Ruth Peters
    aImperial College London UK bDepartment of Cardiovascular Diseases, The Studies Coordinating Centre, Division of Hypertension and Cardiovascular Rehabilitation, University of Leuven, Leuven, Belgium cCentre for Epidemiological Studies and Clinical Trials, The Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China dHôpital Broca, Centre de Gerontologie, 54 56 Rue Pascal, 75013 Paris France eLondon School of Hygiene and Tropical Medicine, London, UK
    J Hypertens 31:1868-75. 2013
    ..There is some evidence to suggest a potential 'J'-shaped relationship between DBP and risk of cognitive impairment. This was investigated using data from the HYpertension in the Very Elderly Trial (HYVET)...
  20. ncbi Treatment of hypertension in patients 80 years of age or older
    Nigel S Beckett
    Care of the Elderly, Division of Medicine, Imperial College London, United Kingdom
    N Engl J Med 358:1887-98. 2008
    ..Whether the treatment of patients with hypertension who are 80 years of age or older is beneficial is unclear. It has been suggested that antihypertensive therapy may reduce the risk of stroke, despite possibly increasing the risk of death...
  21. doi Baseline characteristics of participants in the Hypertension in the Very Elderly Trial (HYVET)
    Christopher John Bulpitt
    Imperial College, Hammersmith Hospital, Care of the Elderly, London, UK
    Blood Press 18:17-22. 2009
    ..Those with prior cardiovascular disease had an excess of the known cardiovascular risk factors. The baseline characteristics provide a basis for further understanding of the HYVET results, which have been published recently...
  22. ncbi Validity of the Clock-Drawing Test as a screening tool for cognitive impairment in the elderly
    Yuji Nishiwaki
    Centre for Ageing and Public Health, London School of Hygiene and Tropical Medicine, University of London, London, United Kingdom
    Am J Epidemiol 160:797-807. 2004
    ..The authors conclude that the CDT may have value as a brief face-to-face screening tool for moderate/severe cognitive impairment in an older community population but is relatively poor at detecting milder cognitive impairment...
  23. doi Does white coat hypertension require treatment over age 80?: Results of the hypertension in the very elderly trial ambulatory blood pressure side project
    Christopher J Bulpitt
    Department of Medicine, Imperial College London, London, United Kingdom
    Hypertension 61:89-94. 2013
    ..Because we estimate that 50% had white coat hypertension in the main study, this condition may benefit from treatment in the very elderly...
  24. ncbi Results of the pilot study for the Hypertension in the Very Elderly Trial
    Christopher J Bulpitt
    Faculty of Medicine, Imperial College London, UK
    J Hypertens 21:2409-17. 2003
    ..The risks and benefits of treating hypertension in individuals older than 80 years are uncertain. A meta-analysis has suggested that a reduction in stroke events of 36% may have to be balanced against a 14% increase in total mortality...
  25. ncbi Rationale and methodology of monitoring ambulatory blood pressure and arterial compliance in the Hypertension in the Very Elderly Trial
    Elisabete Pinto
    Faculty of Medicine, Imperial College London, Hammersmith Campus, UK
    Blood Press Monit 11:3-8. 2006
    ..This is a side project of the Hypertension in the Very Elderly Trial...
  26. ncbi Subgroup and per-protocol analyses from the Hypertension in the Very Elderly Trial
    Nigel Beckett
    aImperial College London, Faculty of Medicine, London, UK bMedical University of Milano, Cardiovascular Rehabilitation and Cardiac Disease Unit, Milan, Italy cMater Hospital, Dublin, Ireland dHypertension and Cardiovascular Rehabilitation Unit, Catholic University of Leuven, Belgium eDepartment Hypertension and Diabetology, Meical University of Gdansk, Poland fWhitby Group Practice, Whitby gLondon School of Hygiene and Tropical Medicine, London, UK All committee members and investigators are listed in the On line Supplement
    J Hypertens 32:1478-87; discussion 1487. 2014
    ..The results of the Hypertension in the Very Elderly Trial showed positive benefits from blood pressure-lowering treatment in those aged 80 and over...
  27. ncbi Prevalence and covariates of electrocardiographic left ventricular hypertrophy in the Hypertension in the Very Elderly Trial
    Riitta L Antikainen
    Care of the Elderly, Imperial College, London, UK
    J Hypertens 31:1224-32. 2013
    ..To estimate the prevalence and covariates of electrocardiographic left ventricular hypertrophy (LVH) in the Hypertension in the Very Elderly Trial...
  28. doi Literature review of the Clock Drawing Test as a tool for cognitive screening
    Elisabete Pinto
    Care of the Elderly, Faculty of Medicine, Imperial College London, London, UK
    Dement Geriatr Cogn Disord 27:201-13. 2009
    ..This systematic review aims to present and discuss the CDT scoring methods available in the literature, in order to find differences in administration and utility of the CDT...
  29. ncbi Does additional feeding support provided by health care assistants improve nutritional status and outcome in acutely ill older in-patients?--a randomised control trial
    Mary Hickson
    Department of Nutrition and Dietetics, Hammersmith Hospitals NHS Trust, Du Cane Road, London W12 0HS, UK
    Clin Nutr 23:69-77. 2004
    ..The aim was to examine whether health care assistants, trained to provide additional support with feeding, can improve acutely ill elderly in-patients' clinical outcomes...
  30. ncbi Romanian subjects entered in the hypertension in the very elderly trial (HYVET)
    D Dumitraşcui
    Iuliu Hatieganu University of Medicine and Pharmacy, 3rd Medical Dept, Cluj Napoca, Romania
    Rom J Intern Med 44:389-96. 2006
    ..Some of these biochemical differences may reflect different methodologies employed in Romanian laboratories, but we could not confirm this possibility...
  31. ncbi Hormonal factors and the risk of invasive ovarian cancer: a population-based case-control study
    Malcolm C Pike
    USC Norris Comprehensive Cancer Center, Keck School of Medicine, Department of Preventive Medicine, University of Southern California, Los Angeles, California 90033, USA
    Fertil Steril 82:186-95. 2004
    ..To examine the influence of hormone-related factors on the risk of invasive epithelial ovarian cancer (ovarian cancer)...
  32. ncbi Galactose-1-phosphate uridyl transferase (GALT) genotype and phenotype, galactose consumption, and the risk of borderline and invasive ovarian cancer (United States)
    Wendy Cozen
    Department of Preventive Medicine, USC Keck School of Medicine, USC Norris Cancer Center, Los Angeles, CA 90033, USA
    Cancer Causes Control 13:113-20. 2002
    ..We examined these issues as part of a large case-control study of ovarian cancer conducted in Los Angeles between 1992 and 1998...