Dj Pennell

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. ncbi request reprint Gadolinium enhanced cardiovascular magnetic resonance in Anderson-Fabry disease. Evidence for a disease specific abnormality of the myocardial interstitium
    James C C Moon
    Centre for Advanced Magnetic Resonance in Cardiology CAMRIC, Royal Brompton Hospital, London, UK
    Eur Heart J 24:2151-5. 2003
  2. ncbi request reprint Quantification of regurgitant fraction in mitral regurgitation by cardiovascular magnetic resonance: comparison of techniques
    Mark W S Kon
    Department of Cardiovascular Magnetic Resonance and Cardiac Surgery, Royal Brompton Hospital, London, UK
    J Heart Valve Dis 13:600-7. 2004
  3. ncbi request reprint Reference right ventricular systolic and diastolic function normalized to age, gender and body surface area from steady-state free precession cardiovascular magnetic resonance
    Alicia M Maceira
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    Eur Heart J 27:2879-88. 2006
  4. doi request reprint Novel technique used to detect swallowing in volume-selective turbo spin-echo (TSE) for carotid artery wall imaging
    Cheuk F Chan
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK
    J Magn Reson Imaging 29:211-6. 2009
  5. pmc Review of Journal of Cardiovascular Magnetic Resonance 2009
    D J Pennell
    CMR Unit Royal Brompton Hospital, Sydney Street, London SW3 6NP UK, National Heart and Lung Institute, Imperial College, Exhibition Road, London, SW7 2AZ UK
    J Cardiovasc Magn Reson 12:15. 2010
  6. pmc International survey of T2* cardiovascular magnetic resonance in β-thalassemia major
    John Paul Carpenter
    Haematologica 98:1368-74. 2013
  7. pmc Reference right atrial dimensions and volume estimation by steady state free precession cardiovascular magnetic resonance
    Alicia M Maceira
    Cardiac Imaging Unit, ERESA, Valencia, Spain
    J Cardiovasc Magn Reson 15:29. 2013
  8. pmc Review of Journal of Cardiovascular Magnetic Resonance 2011
    Dudley J Pennell
    CMR Unit Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    J Cardiovasc Magn Reson 14:78. 2012
  9. pmc Deferasirox for up to 3 years leads to continued improvement of myocardial T2* in patients with β-thalassemia major
    Dudley J Pennell
    Royal Brompton Hospital, London, UK
    Haematologica 97:842-8. 2012
  10. doi request reprint Prognostic importance of late gadolinium enhancement cardiovascular magnetic resonance in cardiomyopathy
    Tevfik F Ismail
    CMR Unit, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    Heart 98:438-42. 2012

Detail Information

Publications90

  1. ncbi request reprint Gadolinium enhanced cardiovascular magnetic resonance in Anderson-Fabry disease. Evidence for a disease specific abnormality of the myocardial interstitium
    James C C Moon
    Centre for Advanced Magnetic Resonance in Cardiology CAMRIC, Royal Brompton Hospital, London, UK
    Eur Heart J 24:2151-5. 2003
    ..Gadolinium enhanced cardiovascular magnetic resonance can detect focal myocardial fibrosis. We hypothesised that hyperenhancement would be present in AFD...
  2. ncbi request reprint Quantification of regurgitant fraction in mitral regurgitation by cardiovascular magnetic resonance: comparison of techniques
    Mark W S Kon
    Department of Cardiovascular Magnetic Resonance and Cardiac Surgery, Royal Brompton Hospital, London, UK
    J Heart Valve Dis 13:600-7. 2004
    ..The study aim was to compare both techniques in a single CMR examination...
  3. ncbi request reprint Reference right ventricular systolic and diastolic function normalized to age, gender and body surface area from steady-state free precession cardiovascular magnetic resonance
    Alicia M Maceira
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    Eur Heart J 27:2879-88. 2006
    ..We used these techniques to establish the reference values for right ventricular (RV) volumes and function...
  4. doi request reprint Novel technique used to detect swallowing in volume-selective turbo spin-echo (TSE) for carotid artery wall imaging
    Cheuk F Chan
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK
    J Magn Reson Imaging 29:211-6. 2009
    ..To improve three-dimensional (3D) volume-selective turbo spin-echo (TSE) carotid wall imaging by the addition of a novel body surface swallowing detection device...
  5. pmc Review of Journal of Cardiovascular Magnetic Resonance 2009
    D J Pennell
    CMR Unit Royal Brompton Hospital, Sydney Street, London SW3 6NP UK, National Heart and Lung Institute, Imperial College, Exhibition Road, London, SW7 2AZ UK
    J Cardiovasc Magn Reson 12:15. 2010
    ..I hope that you find the open-access system increases wider reading and citation of your papers, and that you will continue to send your quality manuscripts to JCMR for publication...
  6. pmc International survey of T2* cardiovascular magnetic resonance in β-thalassemia major
    John Paul Carpenter
    Haematologica 98:1368-74. 2013
    ....
  7. pmc Reference right atrial dimensions and volume estimation by steady state free precession cardiovascular magnetic resonance
    Alicia M Maceira
    Cardiac Imaging Unit, ERESA, Valencia, Spain
    J Cardiovasc Magn Reson 15:29. 2013
    ....
  8. pmc Review of Journal of Cardiovascular Magnetic Resonance 2011
    Dudley J Pennell
    CMR Unit Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    J Cardiovasc Magn Reson 14:78. 2012
    ..We hope that you find the open-access system increases wider reading and citation of your papers, and that you will continue to send your quality manuscripts to JCMR for publication...
  9. pmc Deferasirox for up to 3 years leads to continued improvement of myocardial T2* in patients with β-thalassemia major
    Dudley J Pennell
    Royal Brompton Hospital, London, UK
    Haematologica 97:842-8. 2012
    ..Prospective data on cardiac iron removal are limited beyond one year and longer-term studies are, therefore, important...
  10. doi request reprint Prognostic importance of late gadolinium enhancement cardiovascular magnetic resonance in cardiomyopathy
    Tevfik F Ismail
    CMR Unit, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    Heart 98:438-42. 2012
    ..This paper reviews the evidence for late gadolinium enhancement as a prognostic marker in dilated and hypertrophic cardiomyopathy and highlights the challenges ahead...
  11. pmc Effects of combined deferiprone with deferoxamine on right ventricular function in thalassaemia major
    Francisco Alpendurada
    Royal Brompton and Harefield NHS Foundation Trust, London, UK
    J Cardiovasc Magn Reson 14:8. 2012
    ..We assessed the effects of combination therapy on the RV in thalassaemia major (TM) using cardiovascular magnetic resonance (CMR)...
  12. pmc Right ventricular dysfunction is a predictor of non-response and clinical outcome following cardiac resynchronization therapy
    Francisco Alpendurada
    CMR Unit, Royal Brompton Hospital, Sydney Street, London, SW3 6NP, UK
    J Cardiovasc Magn Reson 13:68. 2011
    ..We investigated the role of RV function, assessed by cardiovascular magnetic resonance (CMR), in predicting response to and major adverse clinical events in HF patients undergoing CRT...
  13. pmc Effect of rosiglitazone on progression of atherosclerosis: insights using 3D carotid cardiovascular magnetic resonance
    Anitha Varghese
    National Heart and Lung Institute, Imperial College, London, UK
    J Cardiovasc Magn Reson 11:24. 2009
    ..There is recent evidence suggesting that rosiglitazone increases death from cardiovascular causes. We investigated the direct effect of this drug on atheroma using 3D carotid cardiovascular magnetic resonance...
  14. pmc Ultra-short echo time cardiovascular magnetic resonance of atherosclerotic carotid plaque
    Cheuk F Chan
    National Heart and Lung Institute, London, UK
    J Cardiovasc Magn Reson 12:17. 2010
    ..The aim of this preliminary study was to show the potential of Ultra-short Echo Time (UTE) subtraction MR in detecting calcification...
  15. pmc Combined chelation therapy in thalassemia major for the treatment of severe myocardial siderosis with left ventricular dysfunction
    Mark A Tanner
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK
    J Cardiovasc Magn Reson 10:12. 2008
    ..Combined chelation therapy with deferiprone and deferoxamine is effective for moderate myocardial siderosis, but has not been prospectively examined in severe myocardial siderosis...
  16. pmc Cardiovascular magnetic resonance and prognosis in cardiac amyloidosis
    Alicia M Maceira
    Cardiac Imaging Unit ERESA Hospital Arnau de Vilanova, Valencia, Spain
    J Cardiovasc Magn Reson 10:54. 2008
    ..In this study we assessed the prognostic value of late gadolinium enhancement (LGE) and gadolinium kinetics in cardiac amyloidosis in a prospective longitudinal study...
  17. doi request reprint Efficacy of deferasirox in reducing and preventing cardiac iron overload in beta-thalassemia
    Dudley J Pennell
    Royal Brompton Hospital, London SW3 6NP, United Kingdom
    Blood 115:2364-71. 2010
    ..7%) to 69.6 (+/- 4.5%) (+1.8%; P < .001). This prospective study shows that deferasirox is effective in removing and preventing myocardial iron accumulation. This study is registered at http://clinicaltrials.gov as NCT00171821...
  18. ncbi request reprint Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report
    Dudley J Pennell
    Royal Brompton Hospital, London, UK
    J Cardiovasc Magn Reson 6:727-65. 2004
  19. ncbi request reprint Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report
    Dudley J Pennell
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    Eur Heart J 25:1940-65. 2004
  20. ncbi request reprint Cardiovascular magnetic resonance: twenty-first century solutions in cardiology
    Dudley J Pennell
    CMR Unit, Royal Brompton Hospital, London
    Clin Med 3:273-8. 2003
    ....
  21. ncbi request reprint Ventricular volume and mass by CMR
    Dudley J Pennell
    Centre for Advanced Magnetic Resonance in Cardiology CAMRIC, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    J Cardiovasc Magn Reson 4:507-13. 2002
  22. ncbi request reprint The carvedilol hibernation reversible ischaemia trial, marker of success (CHRISTMAS) study. Methodology of a randomised, placebo controlled, multicentre study of carvedilol in hibernation and heart failure
    D J Pennell
    Royal Brompton Hospital, London, UK
    Int J Cardiol 72:265-74. 2000
    ..This paper describes the methodology and the rationale for the choice of the nuclear cardiology and echocardiography imaging techniques used in the study...
  23. ncbi request reprint Randomized controlled trial of deferiprone or deferoxamine in beta-thalassemia major patients with asymptomatic myocardial siderosis
    Dudley J Pennell
    Royal Brompton Hospital, Sydney Street, London SW3 6NP, United Kingdom
    Blood 107:3738-44. 2006
    ..There were no episodes of agranulocytosis. Deferiprone monotherapy was significantly more effective than deferoxamine over 1 year in improving asymptomatic myocardial siderosis in beta-thalassemia major...
  24. pmc Nuclear cardiology in the UK 1994: activity relative to Europe, USA, and British Cardiac Society targets
    D J Pennell
    Magnetic Resonance Unit, Royal Brompton Hospital, London, UK
    Heart 80:296-8. 1998
    ..To survey practice in nuclear cardiology in the UK in 1994...
  25. ncbi request reprint T2* magnetic resonance and myocardial iron in thalassemia
    Dudley J Pennell
    CMR Unit, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    Ann N Y Acad Sci 1054:373-8. 2005
    ..These trials will clarify the role of different chelators in the management of myocardial iron overload and may be valuable in reducing the toll of death in thalassemia from heart failure...
  26. pmc Review of journal of cardiovascular magnetic resonance 2010
    Dudley J Pennell
    CMR Unit Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    J Cardiovasc Magn Reson 13:48. 2011
    ..We hope that you find the open-access system increases wider reading and citation of your papers, and that you will continue to send your quality manuscripts to JCMR for publication...
  27. pmc On improvement in ejection fraction with iron chelation in thalassemia major and the risk of future heart failure
    D J Pennell
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London UK
    J Cardiovasc Magn Reson 13:45. 2011
    ..Treatment effects with improved left ventricular (LV) ejection fraction (EF) have been observed in patients without overt heart failure, but it is unclear whether these changes are clinically meaningful...
  28. pmc Continued improvement in myocardial T2* over two years of deferasirox therapy in β-thalassemia major patients with cardiac iron overload
    Dudley J Pennell
    Royal Brompton Hospital, London, UK
    Haematologica 96:48-54. 2011
    ..Since normalization of cardiac T2* takes several years, the efficacy and safety of deferasirox was assessed for two years in patients with β-thalassemia major in the cardiac sub-study of the EPIC trial...
  29. pmc Cardiac T2* magnetic resonance for prediction of cardiac complications in thalassemia major
    P Kirk
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, Sydney St, London SW3 6NP, UK
    Circulation 120:1961-8. 2009
    ..The goal of this study was to determine the predictive value of cardiac T2* magnetic resonance for heart failure and arrhythmia in thalassemia major...
  30. pmc Right ventricular volumes and function in thalassemia major patients in the absence of myocardial iron overload
    John Paul Carpenter
    Cardiovascular MR Unit, Royal Brompton Hospital, London, London, UK
    J Cardiovasc Magn Reson 12:24. 2010
    ..We aimed to define reference ranges for right ventricular (RV) volumes, ejection fraction (EF) in thalassemia major patients (TM) without myocardial iron overload...
  31. ncbi request reprint The histologic basis of late gadolinium enhancement cardiovascular magnetic resonance in hypertrophic cardiomyopathy
    James C C Moon
    Centre for Advanced Magnetic Resonance in Cardiology CAMRIC, London, United Kingdom
    J Am Coll Cardiol 43:2260-4. 2004
    ..We sought to identify the histologic basis of myocardial late gadolinium enhancement cardiovascular magnetic resonance (CMR) in hypertrophic cardiomyopathy (HCM)...
  32. ncbi request reprint Interstudy reproducibility of right ventricular volumes, function, and mass with cardiovascular magnetic resonance
    Frank Grothues
    Centre for Advanced MR in Cardiology, Cardiovascular MR Unit, Royal Brompton Hospital, National Heart and Lung Institute, Imperial College, London, United Kingdom
    Am Heart J 147:218-23. 2004
    ..We sought to determine the interstudy reproducibility of measurements of right ventricular (RV) volumes, function, and mass with CMR and compare it with correspondent LV values...
  33. ncbi request reprint Myocardial iron clearance during reversal of siderotic cardiomyopathy with intravenous desferrioxamine: a prospective study using T2* cardiovascular magnetic resonance
    Lisa J Anderson
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK
    Br J Haematol 127:348-55. 2004
    ..Myocardial T2* improves in concert with LV volumes and function during recovery, but iron clearance from the heart is considerably slower than from the liver...
  34. ncbi request reprint Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia
    Lisa J Anderson
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London SW3 6NP, UK
    Lancet 360:516-20. 2002
    ..The only alternative treatment is oral deferiprone, but its long-term efficacy on myocardial iron concentrations is unknown...
  35. pmc Myocardial T2* measurements in iron-overloaded thalassemia: An in vivo study to investigate optimal methods of quantification
    Taigang He
    National Heart and Lung Institute, Imperial College London, London, UK
    Magn Reson Med 60:1082-9. 2008
    ..The truncation model gave rise to more reproducible T2* measurements, which were also closer to the values obtained from the black-blood data...
  36. ncbi request reprint Development of thalassaemic iron overload cardiomyopathy despite low liver iron levels and meticulous compliance to desferrioxamine
    Lisa J Anderson
    Cardiovascular MR Unit, Royal Brompton Hospital, London, UK
    Acta Haematol 115:106-8. 2006
    ..These indirect markers remained far below the thresholds conventionally believed to be associated with increased cardiac risk...
  37. ncbi request reprint Breath-hold FLASH and FISP cardiovascular MR imaging: left ventricular volume differences and reproducibility
    James C C Moon
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, Sydney St, London SW3 6NP, England
    Radiology 223:789-97. 2002
    ..To compare fast imaging with steady-state precession (FISP) and fast low-angle shot (FLASH) magnetic resonance acquisitions to quantify left ventricular volumes, mass, and function and to determine if the two techniques are comparable...
  38. ncbi request reprint Black-blood T2* technique for myocardial iron measurement in thalassemia
    Taigang He
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital and Imperial College, Sydney Street, London, United Kingdom
    J Magn Reson Imaging 25:1205-9. 2007
    ..To compare the effectiveness and reproducibility of a new black-blood sequence vs. a conventional bright-blood gradient-echo T2* sequence for myocardial iron overload measurement in thalassemia...
  39. ncbi request reprint Development of a novel optimized breathhold technique for myocardial T2 measurement in thalassemia
    Taigang He
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital and Imperial College, London, UK
    J Magn Reson Imaging 24:580-5. 2006
    ..To develop a reproducible fast spin-echo (FSE) technique for accurate myocardial T2 measurement with application to iron overload assessment in thalassemia...
  40. doi request reprint Myocardial T*2 measurement in iron-overloaded thalassemia: an ex vivo study to investigate optimal methods of quantification
    Taigang He
    National Heart and Lung Institute, Imperial College London, UK
    Magn Reson Med 60:350-6. 2008
    ..In this situation the truncation model proves to be reproducible and more accurate than the other models. The study also shows that the nonlinear algorithm is preferred in T*2 curve fitting...
  41. pmc Improved survival of thalassaemia major in the UK and relation to T2* cardiovascular magnetic resonance
    Bernadette Modell
    UCL Centre for Health Informatics and Multiprofessional Education, Holborn Union Building, Whittington Campus, Highgate Hill, London, N19 5LW, UK
    J Cardiovasc Magn Reson 10:42. 2008
    ..A study of survival and causes of death was undertaken which aimed to include the possible impact of T2* cardiovascular magnetic resonance (CMR)...
  42. ncbi request reprint Left ventricular diastolic function compared with T2* cardiovascular magnetic resonance for early detection of myocardial iron overload in thalassemia major
    Mark A Westwood
    Cardiovascular MR Unit, Royal Brompton Hospital and Imperial College, Sydney Street, London SW3 6NP, UK
    J Magn Reson Imaging 22:229-33. 2005
    ..To compare left ventricular (LV) diastolic function with myocardial iron levels in beta thalassemia major (TM) patients, using cardiovascular magnetic resonance (CMR)...
  43. doi request reprint An inter-landmark approach to 4-D shape extraction and interpretation: application to myocardial motion assessment in MRI
    Karim Lekadir
    Institute of Biomedical Engineering, Imperial College London, SW7 2BZ, UK
    IEEE Trans Med Imaging 30:52-68. 2011
    ..The results indicate increased adaptation to spatiotemporal variations and imaging conditions...
  44. ncbi request reprint Myocardial tissue characterization and the role of chronic anemia in sickle cell cardiomyopathy
    Mark A Westwood
    Cardiovascular MR Unit, Royal Brompton Hospital and Imperial College, London, UK
    J Magn Reson Imaging 26:564-8. 2007
    ....
  45. ncbi request reprint Assessment of left ventricular mass regression after aortic valve replacement--cardiovascular magnetic resonance versus M-mode echocardiography
    Kim Rajappan
    Cardiovascular MR Unit, Royal Brompton Hospital, Sydney Street, London, UK
    Eur J Cardiothorac Surg 24:59-65. 2003
    ..The objective of this study therefore was to determine whether quantitative assessment of LVM and regression after AVR using the two techniques was comparable...
  46. ncbi request reprint Functional changes in coronary microcirculation after valve replacement in patients with aortic stenosis
    Kim Rajappan
    Academic Cardiology Unit, St Mary s Hospital, London, UK
    Circulation 107:3170-5. 2003
    ....
  47. doi request reprint On using T2 to assess extrinsic magnetic field inhomogeneity effects on T2* measurements in myocardial siderosis in thalassemia
    Taigang He
    National Heart and Lung Institute, Imperial College London, London, UK
    Magn Reson Med 61:501-6. 2009
    ..89) between myocardial T(2)* and T(2) measurements, which indicates that the iron deposition is the dominant factor in determining these two relaxation values in this scenario...
  48. pmc International reproducibility of single breathhold T2* MR for cardiac and liver iron assessment among five thalassemia centers
    Paul Kirk
    Imperial College and Royal Brompton Hospital, London, United Kingdom
    J Magn Reson Imaging 32:315-9. 2010
    ..To examine the reproducibility of the single breathhold T2* technique from different scanners, after installation of standard methodology in five international centers...
  49. pmc Cardiovascular magnetic resonance in the evaluation of heart failure
    Ravi G Assomull
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK
    Heart 93:985-92. 2007
  50. ncbi request reprint Myocardial late gadolinium enhancement in specific cardiomyopathies by cardiovascular magnetic resonance: a preliminary experience
    Caterina Silva
    Centre for Advanced Magnetic Resonance in Cardiology CAMRIC, Royal Brompton Hospital, London SW3 6NP, UK
    J Cardiovasc Med (Hagerstown) 8:1076-9. 2007
    ..Further systematic studies are warranted to assess whether the pattern and extent of late enhancement may aid diagnosis and prognostic assessment...
  51. pmc Multi-center transferability of a breath-hold T2 technique for myocardial iron assessment
    Taigang He
    National Heart and Lung Institute, Imperial College London, UK
    J Cardiovasc Magn Reson 10:11. 2008
    ..This cardiac T2 technique has good interstudy reproducibility, but its transferability to different centres has not yet been investigated...
  52. doi request reprint Integrated cardiac and vascular assessment in Takayasu arteritis by cardiovascular magnetic resonance
    Niall G Keenan
    Royal Brompton Hospital, London, UK
    Arthritis Rheum 60:3501-9. 2009
    ..This study was undertaken to evaluate the value of cardiovascular magnetic resonance (CMR) in the assessment of patients with Takayasu arteritis (TA)...
  53. doi request reprint Role of T2* magnetic resonance in monitoring iron chelation therapy
    John Paul Carpenter
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK
    Acta Haematol 122:146-54. 2009
    ..T2* can identify early those patients who are at risk of developing cardiac complications, enabling personalised, tailored therapy to avoid potential problems...
  54. ncbi request reprint The role of cardiovascular magnetic resonance in patients presenting with chest pain, raised troponin, and unobstructed coronary arteries
    Ravi G Assomull
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London SW3 6NP, UK
    Eur Heart J 28:1242-9. 2007
    ..However, some patients have no coronary obstruction on angiography, leading to diagnostic uncertainty. We evaluated the incremental diagnostic value of cardiovascular magnetic resonance (CMR) in these patients...
  55. ncbi request reprint Mechanisms of coronary microcirculatory dysfunction in patients with aortic stenosis and angiographically normal coronary arteries
    Kim Rajappan
    Medical Research Council Clinical Sciences Centre, Hammersmith Hospital, London, UK
    Circulation 105:470-6. 2002
    ....
  56. ncbi request reprint Interscanner reproducibility of cardiovascular magnetic resonance T2* measurements of tissue iron in thalassemia
    Mark A Westwood
    Cardiovascular MR Unit, Royal Brompton Hospital, London, United Kingdom
    J Magn Reson Imaging 18:616-20. 2003
    ..To assess interscanner reproducibility of tissue iron measurements in patients with thalassemia using gradient echo T2* measurements on two different MRI scanners...
  57. ncbi request reprint Intercentre reproducibility of magnetic resonance T2* measurements of myocardial iron in thalassaemia
    Mark A Westwood
    CMR Unit, Royal Brompton Hospital, Sydney Street, London, SW3 6NP, UK
    Int J Cardiovasc Imaging 21:531-8. 2005
    ....
  58. ncbi request reprint Myocardial scarring caused by left ventricular assist device (LVAD) insertion demonstrated by cardiovascular magnetic resonance
    James C C Moon
    Cardiovascular Magnetic Resonance Unit of the Royal Brompton Hospital, London, UK
    J Cardiovasc Magn Reson 5:361-3. 2003
    ..The findings suggest that LVAD insertion may cause permanent myocardial fibrosis at the site of ventricular insertion, and the cases demonstrate the use of contrast-enhanced CMR in this scenario of iatrogenic ventricular scarring...
  59. ncbi request reprint Primary myocardial dysfunction in autosomal dominant EDMD. A tissue doppler and cardiovascular magnetic resonance study
    Gillian C Smith
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, and NHLI, Imperial College, London, UK
    J Cardiovasc Magn Reson 8:723-30. 2006
    ..Thus, early detection of cardiac abnormalities may be important for planning early therapeutic intervention...
  60. ncbi request reprint Initial experience with the intravascular contrast agent NC100150-injection (Clariscan) for breath-hold and navigator-gated magnetic resonance coronary artery imaging
    Nicholas H Bunce
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, United Kingdom
    J Magn Reson Imaging 16:217-23. 2002
    ..To examine magnetic resonance coronary artery imaging after NC100150-Injection...
  61. ncbi request reprint Comparison of interstudy reproducibility of cardiovascular magnetic resonance with two-dimensional echocardiography in normal subjects and in patients with heart failure or left ventricular hypertrophy
    Frank Grothues
    Centre for Advanced MR in Cardiology, Cardiovascular MR Unit, Royal Brompton Hospital, National Heart and Lung Institute, Imperial College, London, United Kingdom
    Am J Cardiol 90:29-34. 2002
    ..Thus, CMR has excellent interstudy reproducibility in normal, dilated, and hypertrophic hearts, and is superior to 2-dimensional echocardiography...
  62. ncbi request reprint Aortic distensibility after aortic root replacement assessed with cardiovascular magnetic resonance
    Giovanni Melina
    Academic Department of Cardiothoracic Surgery and Cardiovascular MR Unit, NHLI, The Royal Brompton and Harefield NHS Trust, London, UK
    J Heart Valve Dis 11:67-74; discussion 74. 2002
    ....
  63. ncbi request reprint Evaluation of carotid artery wall volume measurement using novel semiautomated analysis software
    Anitha Varghese
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, United Kingdom
    J Magn Reson Imaging 24:1401-8. 2006
    ..To evaluate semiautomated analysis software for measuring the total carotid arterial wall volume (TWV) as a measure of atheroma burden...
  64. ncbi request reprint A single breath-hold multiecho T2* cardiovascular magnetic resonance technique for diagnosis of myocardial iron overload
    Mark Westwood
    Cardiovascular MR Unit, Royal Brompton Hospital and Imperial College, London, UK
    J Magn Reson Imaging 18:33-9. 2003
    ..To assess tissue iron concentrations by the use of a gradient echo T2* multiecho technique...
  65. ncbi request reprint Assessment of left ventricular mass by cardiovascular magnetic resonance
    Saul G Myerson
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, United Kingdom
    Hypertension 39:750-5. 2002
    ..Cardiovascular magnetic resonance is a suitable tool for this purpose, and this review assesses the technique in comparison with others and examines the clinical and research implications of the improved reproducibility...
  66. ncbi request reprint Images in cardiovascular medicine. Myocardial fibrosis in glycogen storage disease type III
    James C C Moon
    Centre for Advanced Magnetic Resonance in Cardiology, Royal Brompton Hospital, London, UK
    Circulation 107:e47. 2003
  67. ncbi request reprint A comparison of three radionuclide myocardial perfusion tracers in clinical practice: the ROBUST study
    Akhil Kapur
    Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    Eur J Nucl Med Mol Imaging 29:1608-16. 2002
    ..All three tracers perform well in clinical terms, with high sensitivity and specificity for angiographic stenosis and no differences in accuracy between the tracers...
  68. ncbi request reprint Measurement of ventricular volumes and function: a comparison of gated PET and cardiovascular magnetic resonance
    Kim Rajappan
    Cardiovascular MR Unit, Royal Brompton Hospital, National Heart and Lung Institute, London, United Kingdom
    J Nucl Med 43:806-10. 2002
    ..The aim of this study was to compare cardiac volume and function assessment using PET with the reference technique of cardiovascular magnetic resonance (CMR)...
  69. ncbi request reprint Left ventricular mass: reliability of M-mode and 2-dimensional echocardiographic formulas
    Saul G Myerson
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK
    Hypertension 40:673-8. 2002
    ..The technique cannot be recommended either at a single time point or for serial studies in small populations; 3D imaging techniques, such as cardiovascular magnetic resonance, are preferable...
  70. ncbi request reprint Accurate assessment of the arterial input function during high-dose myocardial perfusion cardiovascular magnetic resonance
    Peter D Gatehouse
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK
    J Magn Reson Imaging 20:39-45. 2004
    ..To develop a method for accurate measurement of the arterial input function (AIF) during high-dose, single-injection, quantitative T1-weighted myocardial perfusion cardiovascular magnetic resonance (CMR)...
  71. ncbi request reprint Images in cardiovascular medicine. Reversible wall thinning in hibernation predicted by cardiovascular magnetic resonance
    Anna S John
    Cardiovascular Magnetic Resonance Unit, Royal Brompton and Harefield Hospitals NHS Trust, London, United Kingdom
    Circulation 111:e24-5. 2005
  72. ncbi request reprint Multi-center validation of the transferability of the magnetic resonance T2* technique for the quantification of tissue iron
    Mark A Tanner
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK
    Haematologica 91:1388-91. 2006
    ..0% and 7.1%, with mean absolute differences in T2* of 1.3 ms and 0.45 ms, respectively. The MR multi-breath-hold T2* technique for tissue iron quantification is transferable between scanners with good reproducibility...
  73. ncbi request reprint Normalized left ventricular volumes and function in thalassemia major patients with normal myocardial iron
    Mark A Westwood
    Cardiovascular MR Unit, Royal Brompton Hospital and Imperial College, London, United Kingdom
    J Magn Reson Imaging 25:1147-51. 2007
    ..To determine the reference range in thalassemia major (TM) for left ventricular (LV) function...
  74. ncbi request reprint The histological basis of late gadolinium enhancement cardiovascular magnetic resonance in a patient with Anderson-Fabry disease
    James C Moon
    CMR Unit, Royal Brompton Hospital, London, United Kingdom
    J Cardiovasc Magn Reson 8:479-82. 2006
    ..This scarring may be the substrate for electrical re-entry and sudden arrhythmic death. The reasons for this distribution of fibrosis are unclear, but may reflect inhomogeneous left ventricular wall stress...
  75. pmc Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass
    Enrico Petretto
    Medical Research Council Clinical Sciences Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 0NN, UK
    Nat Genet 40:546-52. 2008
    ..Taken together, these data implicate Ogn as a key regulator of LVM in rats, mice and humans, and suggest that Ogn modifies the hypertrophic response to extrinsic factors such as hypertension and aortic stenosis...
  76. ncbi request reprint Interstudy reproducibility of three-dimensional volume-selective fast spin echo magnetic resonance for quantifying carotid artery wall volume
    Anitha Varghese
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK
    J Magn Reson Imaging 21:187-91. 2005
    ..To assess the interstudy reproducibility of a three-dimensional volume-selective, fast spin echo (FSE) magnetic resonance technique for the assessment of carotid artery wall volume, which is a marker for total carotid plaque volume...
  77. pmc Effects of oral testosterone treatment on myocardial perfusion and vascular function in men with low plasma testosterone and coronary heart disease
    Carolyn M Webb
    Cardiac Medicine, Royal Brompton Campus, National Heart and Lung Institute, Imperial College London, London, United Kingdom
    Am J Cardiol 101:618-24. 2008
    ..The TU-related decrease in basal arterial stiffness may partly explain previously shown effects of exogenous testosterone on signs of exercise-induced myocardial ischemia...
  78. ncbi request reprint Toward clinical risk assessment in hypertrophic cardiomyopathy with gadolinium cardiovascular magnetic resonance
    James C C Moon
    Centre for Advanced Magnetic Resonance in Cardiology CAMRIC, Royal Brompton Hospital, London, United Kingdom
    J Am Coll Cardiol 41:1561-7. 2003
    ..We sought to assess whether hyperenhancement by gadolinium cardiovascular magnetic resonance (CMR) occurs in hypertrophic cardiomyopathy (HCM) and correlates with the risk of heart failure and sudden death...
  79. pmc On T2* magnetic resonance and cardiac iron
    John Paul Carpenter
    Royal Brompton and Harefield NHS Trust, London, SW3 6NP, UK
    Circulation 123:1519-28. 2011
    ....
  80. ncbi request reprint Myocardial iron loading by magnetic resonance imaging T2* in good prognostic myelodysplastic syndrome patients on long-term blood transfusions
    Joseph Chacko
    Department of Haematology, Royal Bournemouth Hospital, Bournemouth, UK
    Br J Haematol 138:587-93. 2007
    ..A long latent period relative to hepatic iron loading appears to predate the development of myocardial iron loading in transfusion-dependent MDS patients...
  81. ncbi request reprint Evaluation of left ventricular function and mass after Medtronic Freestyle versus homograft aortic root replacement using cardiovascular magnetic resonance
    Kim Rajappan
    Cardiovascular MR Unit and Academic Department of Cardiothoracic Surgery, NHLI, Royal Brompton and Harefield NHS Trust, London UK
    J Heart Valve Dis 11:60-5; discussion 66. 2002
    ....
  82. ncbi request reprint Gadobenate dimeglumine-enhanced MR angiography of the abdominal aorta and renal arteries
    Thomas J Kroencke
    Department of Radiology, Universitatsklinikum Charite, Medizinische Fakultat, Humboldt Universitat zu Berlin, Schumannstr 20 21, 10098 Berlin, Germany
    AJR Am J Roentgenol 179:1573-82. 2002
    ..This study was conducted to determine the efficacy and safety of four different doses of gadobenate dimeglumine for contrast-enhanced three-dimensional MR angiography of the abdominal aorta and renal arteries...
  83. ncbi request reprint Comparison between myocardial contrast echocardiography and single-photon emission computed tomography for predicting transmurality of acute myocardial infarction
    Sajad A Hayat
    Department of Cardiology, Northwick Park Hospital, Harrow, United Kingdom
    Am J Cardiol 97:1718-21. 2006
    ..However, MCE is significantly more accurate in predicting >50% of the transmural extent of infarction and more sensitive in identifying <or=25% of the transmural extent of infarction than SPECT...
  84. ncbi request reprint Treatment of cardiac iron overload in thalassemia major
    Mark Westwood
    Haematologica 88:481-2. 2003
  85. ncbi request reprint Atrial dimensions in health and left ventricular disease using cardiovascular magnetic resonance
    Jeffrey L Anderson
    LDS Hospital, University of Utah School of Medicine, Salt Lake City, Utah, USA
    J Cardiovasc Magn Reson 7:671-5. 2005
    ..We assessed atrial size by CMR in healthy and diseased subjects to determine normal adult ranges...
  86. ncbi request reprint Cardiovascular magnetic resonance in endocardial fibroelastosis
    Subha V Raman
    Division of Cardiovascular Medicine, Department of Internal Medicine, The Ohio State University Medical Center, Columbus, Ohio, USA
    J Cardiovasc Magn Reson 7:391-3. 2005
    ..We report a case of endomyocardial fibroelastosis diagnosed by late gadolinium-enhanced CMR and confirmed by endomyocardial biopsy. The patient improved following treatment with imatinib...
  87. ncbi request reprint Integrated evaluation of hypertensive patients with cardiovascular magnetic resonance
    Alicia M Maceira
    Magnetic Resonance Unit, ERESA Hospital Arnau de Vilanova, Valencia, Spain
    Int J Cardiol 125:383-90. 2008
    ..The aim of this study was to prospectively evaluate the feasibility of CMR/CE-MRA to define LV dimensions and exclude some secondary causes in a selected group of hypertensives...
  88. ncbi request reprint Direct comparison of myocardial perfusion cardiovascular magnetic resonance sequences with parallel acquisition
    Jonathan C Lyne
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK
    J Magn Reson Imaging 26:1444-51. 2007
    ..To directly compare the three main myocardial perfusion cardiovascular magnetic resonance (CMR) sequences incorporating parallel acquisition methods...
  89. ncbi request reprint Coronary artery bypass graft patency: assessment with true ast imaging with steady-state precession versus gadolinium-enhanced MR angiography
    Nicholas H Bunce
    Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, Sydney St, London SW3 6NP, England
    Radiology 227:440-6. 2003
    ..To compare the accuracy of multisection true fast imaging with steady-state precession (FISP) with gadolinium-enhanced magnetic resonance (MR) angiography for the detection of coronary artery bypass graft patency...
  90. ncbi request reprint The histology of viable and hibernating myocardium in relation to imaging characteristics
    Mark G Gunning
    Department of Cardiac Imaging, Royal Brompton Hospital and Imperial College School of Medicine, London, United Kingdom
    J Am Coll Cardiol 39:428-35. 2002
    ..This study characterizes the histology of myocardium predicted to be hibernating using three different imaging techniques to explain the discordance among them...