P Pantelidis

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. ncbi request reprint Sequential identification of apoptotic and necrotic cells on individual cytospin preparations
    P Pantelidis
    Interstitial Lung Disease Unit, Occupational and Environmental Medicine, Imperial College at the National Heart and Lung Institute, London, UK
    J Immunol Methods 214:209-12. 1998
  2. ncbi request reprint Analysis of tumor necrosis factor-alpha, lymphotoxin-alpha, tumor necrosis factor receptor II, and interleukin-6 polymorphisms in patients with idiopathic pulmonary fibrosis
    P Pantelidis
    Interstitial Lung Disease Unit, Department of Occupational and Environmental Medicine, Imperial College of Science, Royal Brompton Campus, 1B Manresa Road, London SW3 6LR, United Kingdom
    Am J Respir Crit Care Med 163:1432-6. 2001
  3. ncbi request reprint Human leukocyte antigen-DRB1 position 11 residues are a common protective marker for sarcoidosis
    P J Foley
    Interstitial Lung Disease Unit, Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College of Science, Technology, and Medicine, London, UK
    Am J Respir Cell Mol Biol 25:272-7. 2001
  4. ncbi request reprint Single-nucleotide polymorphisms in the SPARC gene are not associated with susceptibility to scleroderma
    A L Lagan
    Clinical Genomics Group, National Heart and Lung Institute and Royal Brompton Hospital, Imperial College, 1B Manresa Road, London SW3 6LR, UK
    Rheumatology (Oxford) 44:197-201. 2005
  5. pmc Tumour necrosis factor-alpha production in fibrosing alveolitis is macrophage subset specific
    P Pantelidis
    Interstitial Lung Disease Unit, Department of Occupational and Environmental Medicine, Royal Brompton Hospital and National Heart and Lung Institute, London, UK
    Respir Res 2:365-72. 2001
  6. doi request reprint Multiplex immune serum biomarker profiling in sarcoidosis and systemic sclerosis
    P Beirne
    Dept of Respiratory Medicine, Royal Brompton and Harefield NHS Trust, London, UK
    Eur Respir J 34:1376-82. 2009
  7. ncbi request reprint Alveolar macrophages and T cells from sarcoid, but not normal lung, are permissive to adenovirus infection and allow analysis of NF-kappa b-dependent signaling pathways
    M Conron
    Kennedy Institute of Rheumatology, London, United Kingdom
    Am J Respir Cell Mol Biol 25:141-9. 2001
  8. ncbi request reprint BAL findings in idiopathic nonspecific interstitial pneumonia and usual interstitial pneumonia
    S Veeraraghavan
    Interstitial Lung Disease Unit, Dept of Occupational and Environmental Medicine, Royal Brompton Hospital, National Heart and Lung Institute, Imperial College of Science Technology and Medicine, London, UK
    Eur Respir J 22:239-44. 2003
  9. doi request reprint Intracellular cytokine profiles and T cell activation in pulmonary sarcoidosis
    T A Hill
    Department of Clinical Ophthalmology, Institute of Ophthalmology, University College London, London, UK
    Cytokine 42:289-92. 2008
  10. ncbi request reprint Single-cell analysis: a novel approach to tumour necrosis factor-alpha synthesis and secretion in sarcoidosis
    P Pantelidis
    Interstitial Lung Disease Unit, Dept of Occupational and Environmental Medicine, Royal Brompton Hospital and National Heart and Lung Institute, London, UK
    Eur Respir J 20:1179-84. 2002

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Sequential identification of apoptotic and necrotic cells on individual cytospin preparations
    P Pantelidis
    Interstitial Lung Disease Unit, Occupational and Environmental Medicine, Imperial College at the National Heart and Lung Institute, London, UK
    J Immunol Methods 214:209-12. 1998
    ..Identification of trypan blue and TUNEL positive cells in the same section permits the simultaneous assessment of necrotic and apoptotic cells...
  2. ncbi request reprint Analysis of tumor necrosis factor-alpha, lymphotoxin-alpha, tumor necrosis factor receptor II, and interleukin-6 polymorphisms in patients with idiopathic pulmonary fibrosis
    P Pantelidis
    Interstitial Lung Disease Unit, Department of Occupational and Environmental Medicine, Imperial College of Science, Royal Brompton Campus, 1B Manresa Road, London SW3 6LR, United Kingdom
    Am J Respir Crit Care Med 163:1432-6. 2001
    ..These findings, if independently confirmed, will be the first to suggest that disease progression in IPF may be linked to a particular genetic marker or to functional polymorphisms in other genes near that marker...
  3. ncbi request reprint Human leukocyte antigen-DRB1 position 11 residues are a common protective marker for sarcoidosis
    P J Foley
    Interstitial Lung Disease Unit, Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College of Science, Technology, and Medicine, London, UK
    Am J Respir Cell Mol Biol 25:272-7. 2001
    ..This suggests this HLA-DR residue is an important protective marker in sarcoidosis...
  4. ncbi request reprint Single-nucleotide polymorphisms in the SPARC gene are not associated with susceptibility to scleroderma
    A L Lagan
    Clinical Genomics Group, National Heart and Lung Institute and Royal Brompton Hospital, Imperial College, 1B Manresa Road, London SW3 6LR, UK
    Rheumatology (Oxford) 44:197-201. 2005
    ..We set out to reproduce and to positionally clone these disease associations in a set of UK Caucasian scleroderma patients and ethnically matched controls...
  5. pmc Tumour necrosis factor-alpha production in fibrosing alveolitis is macrophage subset specific
    P Pantelidis
    Interstitial Lung Disease Unit, Department of Occupational and Environmental Medicine, Royal Brompton Hospital and National Heart and Lung Institute, London, UK
    Respir Res 2:365-72. 2001
    ..CONCLUSION: By demonstrating the primary cell source of TNF-alpha in FASSc, more accurately targeted, possibly localized, anti-TNF strategies might be employed with success in the future...
  6. doi request reprint Multiplex immune serum biomarker profiling in sarcoidosis and systemic sclerosis
    P Beirne
    Dept of Respiratory Medicine, Royal Brompton and Harefield NHS Trust, London, UK
    Eur Respir J 34:1376-82. 2009
    ..These findings, if they are corroborated by independent studies in other centres, have potential for clinical application and may generate novel insights into the modulation of immune profiles during disease evolution...
  7. ncbi request reprint Alveolar macrophages and T cells from sarcoid, but not normal lung, are permissive to adenovirus infection and allow analysis of NF-kappa b-dependent signaling pathways
    M Conron
    Kennedy Institute of Rheumatology, London, United Kingdom
    Am J Respir Cell Mol Biol 25:141-9. 2001
    ..The results of this study have implications for the future investigation of molecular pathways in inflammatory lung disease...
  8. ncbi request reprint BAL findings in idiopathic nonspecific interstitial pneumonia and usual interstitial pneumonia
    S Veeraraghavan
    Interstitial Lung Disease Unit, Dept of Occupational and Environmental Medicine, Royal Brompton Hospital, National Heart and Lung Institute, Imperial College of Science Technology and Medicine, London, UK
    Eur Respir J 22:239-44. 2003
    ....
  9. doi request reprint Intracellular cytokine profiles and T cell activation in pulmonary sarcoidosis
    T A Hill
    Department of Clinical Ophthalmology, Institute of Ophthalmology, University College London, London, UK
    Cytokine 42:289-92. 2008
    ..The use of intracellular flow cytometry to investigate cytokine production by BAL T cells could help to indicate potential targets for future therapy...
  10. ncbi request reprint Single-cell analysis: a novel approach to tumour necrosis factor-alpha synthesis and secretion in sarcoidosis
    P Pantelidis
    Interstitial Lung Disease Unit, Dept of Occupational and Environmental Medicine, Royal Brompton Hospital and National Heart and Lung Institute, London, UK
    Eur Respir J 20:1179-84. 2002
    ..This study has demonstrated that a subset of mononuclear phagocytes, mature macrophages, are responsible for tumour necrosis factor secretion and this could have implications for targeted management in sarcoidosis in the future...
  11. ncbi request reprint A single round PCR method for genotyping human surfactant protein (SP)-A1, SP-A2 and SP-D gene alleles
    P Pantelidis
    Clinical Genomics Group, Interstitial Lung Disease Unit, Department of Occupational and Environmental Medicine, London, UK
    Tissue Antigens 61:317-21. 2003
    ..In this manuscript, we report the primers and conditions of a sequence specific primer-PCR methodology that enables the identification of SP-A1, SP-A2 and SP-D gene allelic variants directly on genomic DNA material...
  12. ncbi request reprint Ace gene I/D polymorphism and sarcoidosis pulmonary disease severity
    D S McGrath
    Interstitial Lung Disease Unit, Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College of Science, Technology, and Medicine, London, SW3 6LR, UK
    Am J Respir Crit Care Med 164:197-201. 2001
    ..We conclude that the ACE I/D polymorphism has no role in sarcoidosis susceptibility in European whites and that it is not a regulatory variant in this disease...
  13. doi request reprint l-selectin gene polymorphisms and complications of sickle cell disease
    C C Ugochukwu
    Department of Haematology, St Thomas Hospital, University of London, UK
    Int J Lab Hematol 30:312-6. 2008
    ..37, P > 0.05). The findings suggest that these three gene polymorphisms do not predispose to high leukocyte expression of L-selectin, or development of complications in SCD...
  14. ncbi request reprint Increased vitronectin and endothelin-1 in the breath condensate of patients with fibrosing lung disease
    G E Carpagnano
    Institute of Respiratory Diseases, University of Bari, Bari, Italy
    Respiration 70:154-60. 2003
    ..Better understanding of mediators involved in fibrosis may be useful for early diagnosis and in clinical monitoring of disease progression...