Declan P O'Regan

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. doi Salvage assessment with cardiac MRI following acute myocardial infarction underestimates potential for recovery of systolic strain
    Declan P O'Regan
    Robert Steiner MRI Unit, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK
    Eur Radiol 23:1210-7. 2013
  2. pmc Remodeling after acute myocardial infarction: mapping ventricular dilatation using three dimensional CMR image registration
    Declan P O'Regan
    Robert Steiner MRI Unit, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK
    J Cardiovasc Magn Reson 14:41. 2012
  3. ncbi Cardiac T2* and lipid measurement at 3.0 T-initial experience
    Declan P O'Regan
    Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital Campus, London, W12 0NN, UK
    Eur Radiol 18:800-5. 2008
  4. doi Liver fat content and T2*: simultaneous measurement by using breath-hold multiecho MR imaging at 3.0 T--feasibility
    Declan P O'Regan
    Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, United Kingdom
    Radiology 247:550-7. 2008
  5. ncbi Establishing a clinical cardiac MRI service
    D P O'Regan
    Imaging Sciences Department, MRC Clinical Sciences Centre, Hammersmith Hospital Campus, Imperial College, London, UK
    Clin Radiol 61:211-24. 2006
  6. ncbi Reperfusion hemorrhage following acute myocardial infarction: assessment with T2* mapping and effect on measuring the area at risk
    Declan P O'Regan
    Medical Research Council Clinical Sciences Centre, Faculty of Medicine, Imperial College, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, England
    Radiology 250:916-22. 2009
  7. doi Assessment of severe reperfusion injury with T2* cardiac MRI in patients with acute myocardial infarction
    Declan P O'Regan
    MRC Clinical Sciences Centre, Robert Steiner MRI Unit, Faculty of Medicine, Imperial College, Hammersmith Hospital Campus, Du Cane Road, London, UK
    Heart 96:1885-91. 2010
  8. doi Quantitative 3T MR imaging of the descending thoracic aorta: patients with familial hypercholesterolemia have an increased aortic plaque burden despite long-term lipid-lowering therapy
    Stephan A Schmitz
    Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital Campus, Du Cane Rd, London, W12 0NN England
    J Vasc Interv Radiol 19:1403-8. 2008
  9. doi A probabilistic patch-based label fusion model for multi-atlas segmentation with registration refinement: application to cardiac MR images
    Wenjia Bai
    Biomedical Image Analysis Group, Department of Computing, Imperial College London, SW7 2RH London, UK
    IEEE Trans Med Imaging 32:1302-15. 2013
  10. pmc Population-based studies of myocardial hypertrophy: high resolution cardiovascular magnetic resonance atlases improve statistical power
    Antonio de Marvao
    From the Medical Research Council Clinical Sciences Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK
    J Cardiovasc Magn Reson 16:16. 2014

Detail Information

Publications29

  1. doi Salvage assessment with cardiac MRI following acute myocardial infarction underestimates potential for recovery of systolic strain
    Declan P O'Regan
    Robert Steiner MRI Unit, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK
    Eur Radiol 23:1210-7. 2013
    ..Our aim was to evaluate the relationship between the degree of salvage following acute ST elevation myocardial infarction (STEMI) and subsequent reversible contractile dysfunction using cardiac magnetic resonance (CMR) imaging...
  2. pmc Remodeling after acute myocardial infarction: mapping ventricular dilatation using three dimensional CMR image registration
    Declan P O'Regan
    Robert Steiner MRI Unit, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK
    J Cardiovasc Magn Reson 14:41. 2012
    ..Here we use 3D co-registration of Cardiovascular Magnetic Resonance (CMR) images to assess the long-term effects of ischemia-reperfusion injury on left ventricular structure after acute ST-elevation myocardial infarction (STEMI)...
  3. ncbi Cardiac T2* and lipid measurement at 3.0 T-initial experience
    Declan P O'Regan
    Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital Campus, London, W12 0NN, UK
    Eur Radiol 18:800-5. 2008
    ..Cardiac T2* estimation with gradient multiecho imaging at 3.0 T can be achieved with minimal artefact and modelling the signal decay with a biexponential function allows estimation of myocardial lipid content as well as T2* decay...
  4. doi Liver fat content and T2*: simultaneous measurement by using breath-hold multiecho MR imaging at 3.0 T--feasibility
    Declan P O'Regan
    Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, United Kingdom
    Radiology 247:550-7. 2008
    ..Multiecho imaging shows promise as a method of simultaneous fat and T2* quantification...
  5. ncbi Establishing a clinical cardiac MRI service
    D P O'Regan
    Imaging Sciences Department, MRC Clinical Sciences Centre, Hammersmith Hospital Campus, Imperial College, London, UK
    Clin Radiol 61:211-24. 2006
    ..This review will explore these issues from our perspective of a new clinical cardiac MRI service operating over its first year in a teaching hospital imaging department...
  6. ncbi Reperfusion hemorrhage following acute myocardial infarction: assessment with T2* mapping and effect on measuring the area at risk
    Declan P O'Regan
    Medical Research Council Clinical Sciences Centre, Faculty of Medicine, Imperial College, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, England
    Radiology 250:916-22. 2009
    ..8% vs 44.0%, P < .05). T2* mapping is feasible for quantifying post-reperfusion hemorrhage and boundary detection is required to accurately assess the IAR when hemorrhage is present...
  7. doi Assessment of severe reperfusion injury with T2* cardiac MRI in patients with acute myocardial infarction
    Declan P O'Regan
    MRC Clinical Sciences Centre, Robert Steiner MRI Unit, Faculty of Medicine, Imperial College, Hammersmith Hospital Campus, Du Cane Road, London, UK
    Heart 96:1885-91. 2010
    ..Non-invasive assessment of interstitial myocardial haemorrhage by T2* cardiac MRI (T2*-CMR) provides a novel and specific biomarker of severe reperfusion injury which may be of prognostic value...
  8. doi Quantitative 3T MR imaging of the descending thoracic aorta: patients with familial hypercholesterolemia have an increased aortic plaque burden despite long-term lipid-lowering therapy
    Stephan A Schmitz
    Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital Campus, Du Cane Rd, London, W12 0NN England
    J Vasc Interv Radiol 19:1403-8. 2008
    ..To compare the aortic plaque burden in patients with heterozygous familial hypercholesterolemia on long-term statin treatment with that of matched control subjects...
  9. doi A probabilistic patch-based label fusion model for multi-atlas segmentation with registration refinement: application to cardiac MR images
    Wenjia Bai
    Biomedical Image Analysis Group, Department of Computing, Imperial College London, SW7 2RH London, UK
    IEEE Trans Med Imaging 32:1302-15. 2013
    ..92 for the LV cavity, 0.89 for the right ventricular cavity and 0.82 for the myocardium. The results show that the proposed method is able to provide accurate information for clinical diagnosis. ..
  10. pmc Population-based studies of myocardial hypertrophy: high resolution cardiovascular magnetic resonance atlases improve statistical power
    Antonio de Marvao
    From the Medical Research Council Clinical Sciences Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK
    J Cardiovasc Magn Reson 16:16. 2014
    ....
  11. pmc Cardiac MRI of myocardial salvage at the peri-infarct border zones after primary coronary intervention
    Declan P O'Regan
    MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College, Hammersmith Hospital Campus, London, UK
    Am J Physiol Heart Circ Physiol 297:H340-6. 2009
    ..The lateral boundaries of necrosis approximate to the lateral extent of the ischemic bed and systolic wall motion abnormalities extend well beyond the infarct border zone...
  12. doi Body fat is associated with reduced aortic stiffness until middle age
    Ben Corden
    MRC Clinical Sciences Centre, Robert Steiner MRI Unit, Faculty of Medicine, Hammersmith Hospital Campus, Imperial College London, Du Cane Rd, London W12 0NN, UK
    Hypertension 61:1322-7. 2013
    ..23; P=0.002). These findings suggest that the cardiovascular system of young adults may be capable of adapting to the state of obesity and that an adverse association between body fat and aortic stiffness is only apparent in later life...
  13. pmc Impact of number of channels on RF shimming at 3T
    Alexander S Childs
    Robert Steiner MRI Unit, Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital, London, UK
    MAGMA 26:401-10. 2013
    ..In this work, we have investigated the impact of the number of independent channels on the achievable results for both homogeneity improvement and power reduction in vivo...
  14. doi Subject-specific water-selective imaging using parallel transmission
    Shaihan J Malik
    Robert Steiner MRI Unit, Imaging Sciences Department, Hammersmith Hospital Campus, Imperial College London, London, UK
    Magn Reson Med 63:988-97. 2010
    ..72 degrees +/- 0.55 degrees to 0.12 degrees +/- 0.04 degrees for a 20 degrees excitation; uniformity of water excitation also improved, with the standard deviation divided by mean reduced from 0.26 +/- 0.05 to 0.16 +/- 0.05...
  15. doi White matter brain lesions in midlife familial hypercholesterolemic patients at 3-Tesla magnetic resonance imaging
    S A Schmitz
    Imaging Sciences Department and Clinical Research Facility, MRC Clinical Sciences Centre, London, UK
    Acta Radiol 49:184-9. 2008
    ..Patients with hypercholesterolemia of 60 years and older have an increased risk for white matter brain lesions and dementia...
  16. pmc Lipomatous hypertrophy of the interatrial septum: a commonly misdiagnosed mass often leading to unnecessary cardiac surgery
    I Nadra
    Department of Cardiology, National Heart and Lung Institute, Imperial College, Hammersmith Hospital, Du Cane Road, London W12 0HS, UK
    Heart 90:e66. 2004
    ..In such cases an increased awareness of this lesion along with the opinion of a specialist echocardiologist would help to avoid a misdiagnosis and unnecessary intervention...
  17. ncbi [Characterization of an experimental venous thrombus model with MRI, phlebography and histology]
    S A Schmitz
    Klinik und Hochschulambulanz für Radiologie und Nuklearmedizin, Charite, Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin
    Rofo 177:411-9. 2005
    ..It is the purpose of this study to develop a stagnation thrombus model in rabbits and to characterize thrombus at different ages with two (MR) imaging techniques, phlebography and histology...
  18. ncbi Quantitative assessment of iron-oxide-enhanced magnetic resonance imaging of the liver: Vessel isointensity is a potential characteristic of liver hemangiomas on late T1-weighted images
    S A Schmitz
    Klinik und Hochschulambulanz für Radiologie und Nuklearmedizin, Campus Benjamin Franklin, Charite Berlin, Germany
    Acta Radiol 47:634-42. 2006
    ..To test whether a new quantitative measure, the tumor-to-vessel ratio, obtained from late post-iron-oxide-enhanced T1-weighted images allows for differentiating hemangiomas from liver metastases or all malignant liver lesions...
  19. ncbi MRI at 3 Tesla detects no evidence for ischemic brain damage in intensively treated patients with homozygous familial hypercholesterolemia
    Stephan A Schmitz
    Imaging Sciences Department, MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK
    Neuroradiology 49:927-31. 2007
    ..The frequency and extent of ischemic brain damage detectable by high-field magnetic resonance imaging (MRI) after long-term intensive treatment are unknown...
  20. doi Snapshot inversion recovery: an optimized single-shot T1-weighted inversion-recovery sequence for improved fetal brain anatomic delineation
    Christina Malamateniou
    Robert Steiner MRI Unit, Imaging Sciences Department, Clinical Sciences Centre, Hammersmith Hospital Campus, Imperial College, DuCane Rd, London W12 0HS, England
    Radiology 258:229-35. 2011
    ....
  21. doi Right ventricular remodelling in pulmonary arterial hypertension with three-dimensional echocardiography: comparison with cardiac magnetic resonance imaging
    Julia Grapsa
    Department of Cardiovascular Sciences, Hammersmith Hospital, Imperial College London, NHLI, Du Cane Road, W12 0HS London, UK
    Eur J Echocardiogr 11:64-73. 2010
    ..We tested the hypothesis that RV mass, volumes and function could be measured accurately with real-time three-dimensional echocardiography (3DE) in patients with PAH and compared those against cardiac magnetic resonance (CMR)...
  22. ncbi Myocardial infarction in sickle-cell disease
    Jiri Pavlu
    Department of Haematology, Imperial College London, Hammersmith Campus, Du Cane Road, London W12 0NN, UK
    Lancet 369:246. 2007
  23. ncbi Technical report: Magnetic resonance direct thrombus imaging at 3 T field strength in patients with lower limb deep vein thrombosis: a feasibility study
    S A Schmitz
    Imaging Sciences Department, Imperial College, Hammersmith Hospital, London, UK
    Clin Radiol 61:282-6. 2006
    ..0 T magnetic field strength with an optimized a T1 magnetization prepared rapid gradient echo technique (MP-RAGE) in patients with normal volunteers as controls...
  24. ncbi A comparison of MR cholangiopancreatography at 1.5 and 3.0 Tesla
    D P O'Regan
    Imaging Sciences Department Clinical Sciences Centre, Hammersmith Hospital, Faculty of Medicine, Imperial College, London, UK
    Br J Radiol 78:894-8. 2005
    ..043). This pilot study shows that MRCP is feasible at 3.0 Tesla with some improvement in image quality and signal characteristics. Further development may be achieved with sequence optimization and improved coil design...
  25. ncbi [Iron-oxide-enhanced MR imaging of inflammatory atherosclerotic lesions: overview of experimental and initial clinical results]
    S A Schmitz
    Klinik und Poliklinik für Radiologie und Nuklearmedizin, Universitatsklinikum Benjamin Franklin, Berlin
    Rofo 175:469-76. 2003
    ..This article presents the experimental and initial clinical results obtained with iron-oxide-enhanced MRI of atherosclerotic lesions...
  26. ncbi Iron-oxide-enhanced magnetic resonance imaging of atherosclerotic plaques: postmortem analysis of accuracy, inter-observer agreement, and pitfalls
    S A Schmitz
    Department of Radiology and Nuclear Medicine, Benjamin Franklin Medical School, Freie Universitat Berlin, Berlin, Germany
    Invest Radiol 37:405-11. 2002
    ..We determined the accuracy, interobserver agreement, and potential sources of error of this technique by means of postmortem MR imaging of aortic preparations...
  27. ncbi Phase-inversion sonography during the liver-specific late phase of contrast enhancement: improved detection of liver metastases
    T Albrecht
    Department of Radiology and Nuclear Medicine, , , Hindenburgdamm 30, D-12200 Berlin, Germany
    AJR Am J Roentgenol 176:1191-8. 2001
    ..Phase-inversion sonography was particularly advantageous in detecting small metastases and may be a competitive alternative to CT and MR imaging...
  28. ncbi Computed tomography of the human pineal gland for study of the sleep-wake rhythm: reproducibility of a semi-quantitative approach
    S A Schmitz
    Department of Radiology and Nuclear Medicine, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    Acta Radiol 47:865-71. 2006
    ....
  29. ncbi Magnetic resonance imaging of atherosclerotic plaques using superparamagnetic iron oxide particles
    S A Schmitz
    , , , Berlin, Germany
    J Magn Reson Imaging 14:355-61. 2001
    ....