Genomes and Genes
Affiliation: Imperial College
- Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seqMehdi Motallebipour
Department of Genetics and Pathology, Uppsala University, Rudbeck Laboratory, Dag Hammarskjölds väg 20, Uppsala SE 75185, Sweden
Genome Biol 10:R129. 2009..The forkhead box/winged helix family members FOXA1, FOXA2, and FOXA3 are of high importance in development and specification of the hepatic linage and the continued expression of liver-specific genes...
- Molecular interactions between HNF4a, FOXA2 and GABP identified at regulatory DNA elements through ChIP-sequencingOla Wallerman
Department of Genetics and Pathology, Rudbeck Laboratory, SE 751 85 Uppsala, Sweden
Nucleic Acids Res 37:7498-508. 2009..An interaction between HNF4a and GABP was seen at TSS, with one-third of the HNF4a positive promoters being bound also by GABP, and this interaction was verified by co-immunoprecipitations...
- Novel genes in cell cycle control and lipid metabolism with dynamically regulated binding sites for sterol regulatory element-binding protein 1 and RNA polymerase II in HepG2 cells detected by chromatin immunoprecipitation with microarray detectionMehdi Motallebipour
Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden
FEBS J 276:1878-90. 2009..Furthermore, we found evidence of sterol-regulated binding of SREBP-1 and RNA polymerase II to HCFC1 and FLNA. From the results of this work, we infer that SREBP-1 may be involved in processes other than lipid metabolism...
- Two polypyrimidine tracts in the nitric oxide synthase 2 gene: similar regulatory sequences with different propertiesMehdi Motallebipour
Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, 751 85, Uppsala, Sweden
Mol Biol Rep 37:2021-30. 2010..We suggest that both PTBP1 and hnRNPK binds the single strand of the triplex-DNA formed at the CT-repeat in the first intron and that this interaction could be involved in the regulation of NOS2 expression...