N Modi

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. ncbi A randomized, double-blind, controlled trial of the effect of prebiotic oligosaccharides on enteral tolerance in preterm infants (ISRCTN77444690)
    Neena Modi
    Division of Medicine, Section of Neonatal Medicine, Chelsea and Westminster Hospital Campus, Imperial College London, London SW10 9NH, United Kingdom
    Pediatr Res 68:440-5. 2010
  2. pmc The International Network for Evaluating Outcomes of very low birth weight, very preterm neonates (iNeo): a protocol for collaborative comparisons of international health services for quality improvement in neonatal care
    Prakesh S Shah
    Canadian Neonatal Network, Maternal Infant Care Research Centre, Mount Sinai Hospital, 700 University Avenue, Toronto, Ontario M5G 1X6, Canada
    BMC Pediatr 14:110. 2014
  3. ncbi Avoiding sedation in research MRI and spectroscopy in infants: our approach, success rate and prevalence of incidental findings
    Christopher Gale
    Section of Neonatal Medicine, Department of Medicine, Imperial College London, Chelsea and Westminster Hospital Campus, 369 Fulham Road, London, SW10 9NH, UK
    Arch Dis Child Fetal Neonatal Ed 98:F267-8. 2013
  4. ncbi Preterm birth and the metabolic syndrome in adult life: a systematic review and meta-analysis
    James R C Parkinson
    Section of Neonatal Medicine, Department of Medicine, Imperial College London, London SW10 9NH, United Kingdom
    Pediatrics 131:e1240-63. 2013
  5. ncbi A healthy nation: strengthening child health research in the UK
    Neena Modi
    Imperial College London, Chelsea and Westminster Hospital, London, UK
    Lancet 381:73-87. 2013
  6. ncbi Determinants of adiposity during preweaning postnatal growth in appropriately grown and growth-restricted term infants
    Neena Modi
    Faculty of Medicine, Imperial College London, Chelsea and Westminster Hospital, London SW10 9NH, UK
    Pediatr Res 60:345-8. 2006
  7. ncbi Promoting research for children
    Neena Modi
    Faculty of Medicine, Section of Neonatal Medicine, Department of Medicine, Imperial College London, Chelsea and Westminster Hospital Campus, 369 Fulham Road, London, UK
    Arch Dis Child 95:941-4. 2010
  8. ncbi Clinical implications of postnatal alterations in body water distribution
    Neena Modi
    Faculty of Medicine, Imperial College of Science, Technology and Medicine, Chelsea and Westminster Hospital, London, UK
    Semin Neonatol 8:301-6. 2003
  9. pmc Avoiding hypernatraemic dehydration in healthy term infants
    Neena Modi
    Imperial College London, Chelsea and Westminster Campus, 369 Fulham Road, London, UK
    Arch Dis Child 92:474-5. 2007
  10. ncbi The influence of maternal body mass index on infant adiposity and hepatic lipid content
    Neena Modi
    Department of Medicine, Imperial College London, London, UK
    Pediatr Res 70:287-91. 2011

Collaborators

  • E L Thomas
  • V Vasu
  • A Holmes
  • K Costeloe
  • J C K Wells
  • Matthew J Hyde
  • Helen Budge
  • G Frost
  • R Coello
  • J L Y Cheong
  • K B Bamford
  • Vivette Glover
  • Rikke Ruager-Martin
  • R Ashley
  • C Yajnik
  • C Gale
  • S Santhakumaran
  • C Battersby
  • L H Philipps
  • S Uthaya
  • Sabita Uthaya
  • Prakesh S Shah
  • Christopher Gale
  • James R C Parkinson
  • A Aceti
  • K M Logan
  • E Prior
  • Robert Carr
  • L Bye
  • Caroline J Doré
  • Rachel Miles
  • J Cockerill
  • Jimmy Bell
  • Tracey A M Harrington
  • G Karthikeyan
  • Brian Darlow
  • Mark Adams
  • Gunnar Sjörs
  • Ross Haslam
  • Shoo K Lee
  • Satoshi Kusuda
  • T A M Harrington
  • Rintaro Mori
  • Lucia Mirea
  • J Birch
  • Brian Reichman
  • L Radbone
  • Kei Lui
  • Masanori Fujimura
  • Laura San Feliciano
  • Stellan Håkansson
  • M Upton
  • Suzan Jeffries
  • Chris Gale
  • Shalini Santhakumaran
  • Karyn E Chappell
  • Karen Mary Logan
  • Sabita N Uthaya
  • S Nagarajan
  • Y Statnikov
  • Peter Brocklehurst
  • F Fortune
  • G R Wallace
  • C Kanawati
  • M R Stanford
  • M Ghabra
  • P I Murray
  • E Kondeatis
  • R Vaughan
  • E Ben-Chetrit
  • Jim Stevenson
  • C J Dore
  • Frances Cowan
  • Gavin Hamilton
  • Jimmy D Bell
  • J D Bell
  • G A Coutts

Detail Information

Publications41

  1. ncbi A randomized, double-blind, controlled trial of the effect of prebiotic oligosaccharides on enteral tolerance in preterm infants (ISRCTN77444690)
    Neena Modi
    Division of Medicine, Section of Neonatal Medicine, Chelsea and Westminster Hospital Campus, Imperial College London, London SW10 9NH, United Kingdom
    Pediatr Res 68:440-5. 2010
    ..9% at 26-wk gestation; p < 0.001) but decreased or no benefit in babies >31-wk gestation. Prebiotic supplementation appears safe and may benefit enteral tolerance in the most immature infants...
  2. pmc The International Network for Evaluating Outcomes of very low birth weight, very preterm neonates (iNeo): a protocol for collaborative comparisons of international health services for quality improvement in neonatal care
    Prakesh S Shah
    Canadian Neonatal Network, Maternal Infant Care Research Centre, Mount Sinai Hospital, 700 University Avenue, Toronto, Ontario M5G 1X6, Canada
    BMC Pediatr 14:110. 2014
    ....
  3. ncbi Avoiding sedation in research MRI and spectroscopy in infants: our approach, success rate and prevalence of incidental findings
    Christopher Gale
    Section of Neonatal Medicine, Department of Medicine, Imperial College London, Chelsea and Westminster Hospital Campus, 369 Fulham Road, London, SW10 9NH, UK
    Arch Dis Child Fetal Neonatal Ed 98:F267-8. 2013
    ..The prevalence of incidental findings on whole body (excluding brain) MRI in our cohort was 0.8%. We conclude that the use of sedation for research MRI in this group is not necessary. Our approach to MRI in infancy is also described...
  4. ncbi Preterm birth and the metabolic syndrome in adult life: a systematic review and meta-analysis
    James R C Parkinson
    Section of Neonatal Medicine, Department of Medicine, Imperial College London, London SW10 9NH, United Kingdom
    Pediatrics 131:e1240-63. 2013
    ..Preterm birth is associated with features of the metabolic syndrome in later life. We performed a systematic review and meta-analysis of studies reporting markers of the metabolic syndrome in adults born preterm...
  5. ncbi A healthy nation: strengthening child health research in the UK
    Neena Modi
    Imperial College London, Chelsea and Westminster Hospital, London, UK
    Lancet 381:73-87. 2013
    ....
  6. ncbi Determinants of adiposity during preweaning postnatal growth in appropriately grown and growth-restricted term infants
    Neena Modi
    Faculty of Medicine, Imperial College London, Chelsea and Westminster Hospital, London SW10 9NH, UK
    Pediatr Res 60:345-8. 2006
    ..Low total adipose tissue quantity at birth appears to direct nutrition toward head growth. Adipose tissue may be involved in the signaling of catch-up growth...
  7. ncbi Promoting research for children
    Neena Modi
    Faculty of Medicine, Section of Neonatal Medicine, Department of Medicine, Imperial College London, Chelsea and Westminster Hospital Campus, 369 Fulham Road, London, UK
    Arch Dis Child 95:941-4. 2010
    ..Here I consider the extent to which these concerns are justified, the sweeping changes that have taken place in research funding, governance and organisation, and necessary action to take...
  8. ncbi Clinical implications of postnatal alterations in body water distribution
    Neena Modi
    Faculty of Medicine, Imperial College of Science, Technology and Medicine, Chelsea and Westminster Hospital, London, UK
    Semin Neonatol 8:301-6. 2003
    ..Clinical management must be tailored to the pace of postnatal adaptation, and the neonatal physician must be aware of these alterations in order to promote both normal physiological change and growth...
  9. pmc Avoiding hypernatraemic dehydration in healthy term infants
    Neena Modi
    Imperial College London, Chelsea and Westminster Campus, 369 Fulham Road, London, UK
    Arch Dis Child 92:474-5. 2007
  10. ncbi The influence of maternal body mass index on infant adiposity and hepatic lipid content
    Neena Modi
    Department of Medicine, Imperial College London, London, UK
    Pediatr Res 70:287-91. 2011
    ..Infant abdominal AT and liver lipid increase with increasing maternal BMI across the normal range. These effects may be the initiating determinants of a life-long trajectory leading to adverse metabolic health...
  11. ncbi A case definition for national and international neonatal bloodstream infection surveillance
    N Modi
    Division of Medicine, Section of Neonatal Medicine, Imperial College London, London, UK
    Arch Dis Child Fetal Neonatal Ed 94:F8-12. 2009
    ..As this might represent either genuine BSI or contamination, clinical correlates are necessary, but this adds to the difficulty of agreeing an objective, standardised case definition...
  12. ncbi Whole body magnetic resonance imaging of healthy newborn infants demonstrates increased central adiposity in Asian Indians
    Neena Modi
    Section of Neonatal Medicine, Division of Medicine, Chelsca and Westminister Hospital Campus, Imperial College London, London SW10 9NH, UK
    Pediatr Res 65:584-7. 2009
    ..175 to 0.034 L, p = 0.2). We conclude that differences in adipose tissue partitioning exist at birth. Investigative, screening, and preventive measures must involve maternal health, intrauterine life, and infancy...
  13. pmc Accelerated postnatal head growth follows preterm birth
    J Cockerill
    Faculty of Medicine, Imperial College London, Chelsea and Westminster Hospital, 369 Fulham Road, London, SW10 9NH
    Arch Dis Child Fetal Neonatal Ed 91:F184-7. 2006
    ..Poor growth after preterm birth, particularly poor head growth, is associated with impaired neurodevelopmental outcome...
  14. ncbi Risk management in neonatal research
    Neena Modi
    Department of Pediatrics, Faculty of Medicine, Imperial College, Chelsea and Westminster Hospital, 4th Floor, 369 Fulham Road, London SW10 9NH, UK
    Semin Fetal Neonatal Med 10:99-104. 2005
    ..Risk management acknowledges that risks exist. It involves adherence to good standards of practice, the means to demonstrate good practice and ensuring that mechanisms are in place to deal with problems that might arise...
  15. pmc Management of fluid balance in the very immature neonate
    N Modi
    Faculty of Medicine, Imperial College of Science, Technology and Medicine, Westminster Hospital, London, UK
    Arch Dis Child Fetal Neonatal Ed 89:F108-11. 2004
    ..Preterm birth requires rapid adaptation from a liquid to a gaseous, low humidity environment. There are several ways in which this can be facilitated. The management of sodium and water balance is considered here...
  16. ncbi Risk factors and recommendations for rate stratification for surveillance of neonatal healthcare-associated bloodstream infection
    A Holmes
    Division of Investigative Sciences, Imperial College London, UK
    J Hosp Infect 68:66-72. 2008
    ....
  17. ncbi Neonatal intrahepatocellular lipid
    E L Thomas
    Molecular Imaging Group, MRC Clinical Sciences Centre, Imperial College London, London, UK
    Arch Dis Child Fetal Neonatal Ed 93:F382-3. 2008
    ..In preterm-at-term infants IHCL was significantly elevated when compared with term-born infants and with adults (IHCL CH2/water median (interquartile range): preterm 1.69 (1.04-3.53), term 0.21 (0-0.54) and adult 0.55 (0.08-1.57)...
  18. ncbi Early nutritional determinants of intrahepatocellular lipid deposition in preterm infants at term age
    V Vasu
    Section of Neonatal Medicine, Department of Medicine, Imperial College London, Chelsea and Westminster Campus, London, UK
    Int J Obes (Lond) 37:500-4. 2013
    ..Preterm nutritional intake is a plausible determinant of these aberrant trajectories of development...
  19. ncbi The diabetic pregnancy and offspring blood pressure in childhood: a systematic review and meta-analysis
    A Aceti
    Section of Neonatal Medicine, Department of Medicine, Imperial College London, Chelsea and Westminster Campus, 369 Fulham Road, London SW10 9NH, UK
    Diabetologia 55:3114-27. 2012
    ..Studies examining BP in offspring of diabetic mothers have conflicting conclusions. We performed a systematic review and meta-analysis of studies reporting offspring BP in children born to diabetic mothers...
  20. ncbi Glucocorticoid exposure in preterm babies predicts saliva cortisol response to immunization at 4 months
    Vivette Glover
    Wolfson and Weston Research Centre for Family Health, Institute of Reproductive and Developmental Biology, Imperial College London, UK
    Pediatr Res 58:1233-7. 2005
    ..This provides evidence that the magnitude of glucocorticoid exposure, both endogenous and exogenous, may have an effect on later stress responses...
  21. ncbi The impact of a regional care bundle on maternal breast milk use in preterm infants: outcomes of the East of England quality improvement programme
    C Battersby
    Neonatal Data Analysis Unit, Imperial College, London, UK
    Arch Dis Child Fetal Neonatal Ed 99:F395-401. 2014
    ..To evaluate a quality improvement (QI) programme to increase the use of maternal breast milk (MBM) in preterm infants...
  22. pmc Impact of managed clinical networks on NHS specialist neonatal services in England: population based study
    C Gale
    Section of Neonatal Medicine, Department of Medicine, Chelsea and Westminster Campus, Imperial College London, London SW10 9NH, UK
    BMJ 344:e2105. 2012
    ..To assess the impact of reorganisation of neonatal specialist care services in England after a UK Department of Health report in 2003...
  23. ncbi The diabetic pregnancy and offspring BMI in childhood: a systematic review and meta-analysis
    L H Philipps
    Section of Neonatal Medicine, Department of Medicine, Imperial College London, Chelsea and Westminster Campus, 369 Fulham Road, London, SW10 9NH, UK
    Diabetologia 54:1957-66. 2011
    ..Increased offspring BMI is a plausible mediator. We performed a systematic review and meta-analysis of studies examining offspring BMI z score in childhood in relation to maternal diabetes...
  24. ncbi PC.14 Adjustment of directly measured adipose tissue volume in infants
    C Gale
    Section of Neonatal Medicine, Chelsea and Westminster Hospital Campus, Imperial College London, London, UK
    Arch Dis Child Fetal Neonatal Ed 99:A40-1. 2014
    ..Direct measurement of adipose tissue using magnetic resonance imaging (MRI) is increasingly used to characterise body composition. Optimal techniques for adjusting direct measures of infant adipose tissue remain to be determined...
  25. pmc Adjustment of directly measured adipose tissue volume in infants
    C Gale
    Section of Neonatal Medicine, Chelsea and Westminster Hospital Campus, Imperial College London, London, UK
    Int J Obes (Lond) 38:995-9. 2014
    ..Direct measurement of adipose tissue (AT) using magnetic resonance imaging is increasingly used to characterise infant body composition. Optimal techniques for adjusting direct measures of infant AT remain to be determined...
  26. ncbi Altered adiposity after extremely preterm birth
    Sabita Uthaya
    Division of Paediatrics, Obstetrics and Gynaecology, Faculty of Medicine, Imperial College London, Chelsea and Westminster Hospital, 369 Fulham Rd, London SW10 9NH, UK
    Pediatr Res 57:211-5. 2005
    ..We suggest that these observations may in part explain the associations between small size at birth and later disease. Preterm infants may be at risk in later life of metabolic complications through increased and aberrant adiposity...
  27. ncbi A controlled trial of skin-to-skin contact in extremely preterm infants
    Rachel Miles
    Faculty of Medicine, Imperial College London, Chelsea and Westminster Hospital, 369 Fulham Road, London SW10 9NH, UK
    Early Hum Dev 82:447-55. 2006
    ..Mother-infant skin-to-skin contact has been recommended as a simple means of ameliorating these effects...
  28. ncbi Practical preterm parenteral nutrition: systematic literature review and recommendations for practice
    S Uthaya
    Imperial College London, UK Chelsea Westminster Hospital NHS Foundation Trust, London, UK Electronic address
    Early Hum Dev 90:747-53. 2014
    ..We suggest principles to guide practice based on evidence from a systematic search and review of evidence to date, and recommend actions necessary to advance the understanding of this important aspect of preterm care. ..
  29. ncbi PC.15 The UK Neonatal Collaborative Necrotising Enterocolitis (NEC) Study: development of an evidence-based case-definition for NEC
    C Battersby
    Imperial College London, London, UK
    Arch Dis Child Fetal Neonatal Ed 99:A41. 2014
    ..Bell's staging, although widely used, was devised to guide surgical management after diagnosis(1). We aimed to develop an evidence-based NEC case-definition...
  30. pmc Gastrointestinal manifestations of postnatal cytomegalovirus infection in infants admitted to a neonatal intensive care unit over a five year period
    J L Y Cheong
    Division of Paediatrics, Obstetrics and Gynaecology, Faculty of Medicine, Imperial College, 369 Fulham Road, London SW10 9NH, UK
    Arch Dis Child Fetal Neonatal Ed 89:F367-9. 2004
    ..It is suggested that CMV enteritis is added to the spectrum of clinical manifestations of postnatal CMV infection. Signs suggestive of necrotising enterocolitis with atypical features should prompt investigations for CMV infection...
  31. ncbi Fast and reproducible method for the direct quantitation of adipose tissue in newborn infants
    T A M Harrington
    The Robert Steiner MRI Unit, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom
    Lipids 37:95-100. 2002
    ..Furthermore, its noninvasive nature makes it an ideal method for longitudinal and interventional studies in newborn infants...
  32. ncbi CTLA-4 polymorphisms are not associated with ocular inflammatory disease
    L Bye
    Department of Ophthalmology, King s College London, London, UK
    Tissue Antigens 72:49-53. 2008
    ..The lack of association with polymorphisms in CTLA-4 and other master controlling genes of autoimmunity suggests that mechanisms that mediate such a description for BD and intermediate uveitis have still to be elucidated...
  33. ncbi Distribution of adipose tissue in the newborn
    Tracey A M Harrington
    Division of Paediatrics, Obstetrics and Gynaecology, Faculty of Medicine, Imperial College, Chelsea and Westminster Hospital, 369 Fulham Rd, London SW10 9NH, UK
    Pediatr Res 55:437-41. 2004
    ..This suggests that subcutaneous and intra-abdominal adipose tissue compartments may be under different regulatory control during intrauterine life...
  34. ncbi Adipose tissue magnetic resonance imaging in the newborn
    Sabita Uthaya
    Division of Paediatrics, Obstetrics and Gynaecology, Chelsea and Westminster Hospital, Imperial College London, UK
    Horm Res 62:143-8. 2004
    ..We have adapted this technique for application to newborns and, to date, have imaged over 100 term and preterm infants...
  35. ncbi Assessing the impact of preterm nutrition
    Vimal Vasu
    Division of Medicine, Imperial College London, Chelsea and Westminster Campus, London, UK
    Early Hum Dev 83:813-8. 2007
    ..Clinical practice should include the systematic capture of neonatal nutritional intake. As the ultimate goals are adult health and wellbeing, long-term follow-up is essential...
  36. ncbi Granulocyte-macrophage colony stimulating factor administered as prophylaxis for reduction of sepsis in extremely preterm, small for gestational age neonates (the PROGRAMS trial): a single-blind, multicentre, randomised controlled trial
    Robert Carr
    Department of Haematology, Guy s and St Thomas Hospital, King s College, London, UK
    Lancet 373:226-33. 2009
    ..We assessed whether granulocyte-macrophage colony stimulating factor (GM-CSF) administered as prophylaxis to preterm neonates at high risk of neutropenia would reduce sepsis, mortality, and morbidity...
  37. ncbi Fluid balance and renal function
    Neena Modi
    Semin Neonatol 8:267. 2003
  38. ncbi Neonatal Hypernatremia due to high Breast milk sodium
    G Karthikeyan
    Indian Pediatr 40:72-3; author reply 73-5. 2003
  39. pmc Donor breast milk banking
    Neena Modi
    BMJ 333:1133-4. 2006
  40. pmc Survival after extremely preterm birth
    Neena Modi
    BMJ 336:1199-200. 2008
  41. ncbi The Neonatal Update 2006: "the science of newborn care"
    Neena Modi
    Early Hum Dev 82:753. 2006