Fiona E McCann

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. pmc Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis
    Fiona E McCann
    The Kennedy Institute of Rheumatology, Imperial College London, 65 Aspenlea Road, London, W6 8LH, UK
    Arthritis Res Ther 12:R107. 2010
  2. doi request reprint ANTI-CD3 therapy expands the numbers of CD4+ and CD8+ Treg cells and induces sustained amelioration of collagen-induced arthritis
    Clare A Notley
    Imperial College London, London, UK
    Arthritis Rheum 62:171-8. 2010
  3. pmc Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells
    Clare A Notley
    Kennedy Institute of Rheumatology Division, Imperial College London, London, W6 8LH, England, UK
    J Exp Med 205:2491-7. 2008
  4. pmc New developments in the management of psoriasis and psoriatic arthritis: a focus on apremilast
    Andrew C Palfreeman
    The Kennedy Institute of Rheumatology, Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, London, UK
    Drug Des Devel Ther 7:201-10. 2013
  5. doi request reprint Protocol for the induction of arthritis in C57BL/6 mice
    Julia J Inglis
    Kennedy Institute of Rheumatology Division, Imperial College London, 1 Aspenlea Road, London W6 8LH, UK
    Nat Protoc 3:612-8. 2008
  6. doi request reprint Blockade of NKG2D ameliorates disease in mice with collagen-induced arthritis: a potential pathogenic role in chronic inflammatory arthritis
    Anna K Andersson
    Imperial College London, London, UK
    Arthritis Rheum 63:2617-29. 2011

Detail Information

Publications6

  1. pmc Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis
    Fiona E McCann
    The Kennedy Institute of Rheumatology, Imperial College London, 65 Aspenlea Road, London, W6 8LH, UK
    Arthritis Res Ther 12:R107. 2010
    ..We assessed the anti-inflammatory effects of a novel PDE4 inhibitor, apremilast, in human synovial cells from rheumatoid arthritis (RA) patients, as well as two murine models of arthritis...
  2. doi request reprint ANTI-CD3 therapy expands the numbers of CD4+ and CD8+ Treg cells and induces sustained amelioration of collagen-induced arthritis
    Clare A Notley
    Imperial College London, London, UK
    Arthritis Rheum 62:171-8. 2010
    ..To assess the therapeutic potential of anti-CD3 monoclonal antibodies (mAb) for rheumatoid arthritis, using collagen-induced arthritis as an animal model...
  3. pmc Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells
    Clare A Notley
    Kennedy Institute of Rheumatology Division, Imperial College London, London, W6 8LH, England, UK
    J Exp Med 205:2491-7. 2008
    ....
  4. pmc New developments in the management of psoriasis and psoriatic arthritis: a focus on apremilast
    Andrew C Palfreeman
    The Kennedy Institute of Rheumatology, Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, London, UK
    Drug Des Devel Ther 7:201-10. 2013
    ....
  5. doi request reprint Protocol for the induction of arthritis in C57BL/6 mice
    Julia J Inglis
    Kennedy Institute of Rheumatology Division, Imperial College London, 1 Aspenlea Road, London W6 8LH, UK
    Nat Protoc 3:612-8. 2008
    ..The incidence of arthritis varies from 50 to 80% and is milder than the classical collagen-induced arthritis model. This procedure takes approximately 3 months to complete...
  6. doi request reprint Blockade of NKG2D ameliorates disease in mice with collagen-induced arthritis: a potential pathogenic role in chronic inflammatory arthritis
    Anna K Andersson
    Imperial College London, London, UK
    Arthritis Rheum 63:2617-29. 2011
    ..To assess the role of the activating receptor NKG2D in arthritis...