M MazeSummaryAffiliation: Imperial College Country: UK Publications
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Publications
New agents for sedation in the intensive care unitM Maze
Sir Ivan Magill Department of Anaesthetics and Intensive Care, Division of Surgery, Anaesthetics, and Intensive Care, Imperial College School of Medicine, Chelsea and Westminster Hospital, London, United Kingdom
Crit Care Clin 17:881-97. 2001..Lorazepam seems to be finding more proponents, especially in long-term ICU sedation where the costs of the newer agents may be prohibitive...
Balancing paediatric anaesthesia: preclinical insights into analgesia, hypnosis, neuroprotection, and neurotoxicityR D Sanders
Department of Anaesthetics, Pain Medicine and Intensive Care, Faculty of Medicine, Imperial College London, London, UK
Br J Anaesth 101:597-609. 2008..We review the current state of preclinical research in paediatric anaesthesia and identify areas which require further exploration in order to provide the foundations for well-conducted clinical trials...
Substitution of a mutant alpha2a-adrenergic receptor via "hit and run" gene targeting reveals the role of this subtype in sedative, analgesic, and anesthetic-sparing responses in vivoP P Lakhlani
Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA
Proc Natl Acad Sci U S A 94:9950-5. 1997....
The sedative component of anesthesia is mediated by GABA(A) receptors in an endogenous sleep pathwayL E Nelson
Department of Anaesthetics and Intensive Care, Chelsea and Westminster Hospital, Imperial College School of Medicine, London SW10 9NH, UK
Nat Neurosci 5:979-84. 2002..We conclude that the TMN is a discrete neural locus that has a key role in the sedative response to GABAergic anesthetics...
Neuroprotective and neurotoxic properties of the 'inert' gas, xenonD Ma
Magill Department of Anaesthesia, Chelsea and Westminster Hospital and Biophysics Group, The Blackett Laboratory, Imperial College of Science, Technology and Medicine, London, UK
Br J Anaesth 89:739-46. 2002..The reason why ketamine and nitrous oxide, but not xenon, produce neurotoxicity may involve their actions on dopaminergic pathways...
Evaluation of high fidelity patient simulator in assessment of performance of anaesthetistsJ M Weller
Department of Surgery, Wellington School of Medicine, Otago University, Private Bag 7343, Wellington South, New Zealand
Br J Anaesth 90:43-7. 2003..We set out to assess the reliability of a global rating scale for scoring simulator performance in crisis management...
Xenon: no stranger to anaesthesiaR D Sanders
Department of Anaesthetics and Intensive Care, Faculty of Medicine, Imperial College London, UK
Br J Anaesth 91:709-17. 2003
Asynchronous administration of xenon and hypothermia significantly reduces brain infarction in the neonatal ratJ L Martin
Department of Anaesthetics, Pain Medicine, and Intensive Care, Imperial College London, London, UK
Br J Anaesth 98:236-40. 2007..This study sought to investigate whether asynchronous administration of xenon and hypothermia is capable of combining synergistically to provide neuroprotection...
