Mark P Little

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. ncbi request reprint A comparison of the degree of curvature in the cancer incidence dose-response in Japanese atomic bomb survivors with that in chromosome aberrations measured in vitro
    M P Little
    Department of Epidemiology and Public Health, Imperial College School of Medicine, St Mary s Campus, London, UK
    Int J Radiat Biol 76:1365-75. 2000
  2. ncbi request reprint The bystander effect in experimental systems and compatibility with radon-induced lung cancer in humans
    M P Little
    Department of Epidemiology and Public Health, Imperial College of Science, Technology and Medicine, London, UK
    J Radiol Prot 22:A27-31. 2002
  3. ncbi request reprint The proportion of thyroid cancers in the Japanese atomic bomb survivors associated with natural background radiation
    M P Little
    Department of Epidemiology and Public Health, Imperial College of Science, Technology and Medicine, London, UK
    J Radiol Prot 22:279-91. 2002
  4. ncbi request reprint Cancer after exposure to radiation in the course of treatment for benign and malignant disease
    M P Little
    Department of Epidemiology and Public Health, Imperial College School of Medicine, London, UK
    Lancet Oncol 2:212-20. 2001
  5. ncbi request reprint Comparisons of lung tumour mortality risk in the Japanese A-bomb survivors and in the Colorado Plateau uranium miners: support for the ICRP lung model
    M P Little
    Department of Epidemiology and Public Health, Imperial College of Science, Technology and Medicine, St Mary s Campus, Norfolk Place, London, W2 1PG, UK
    Int J Radiat Biol 78:145-63. 2002
  6. ncbi request reprint Modelling lung tumour risk in radon-exposed uranium miners using generalizations of the two-mutation model of Moolgavkar, Venzon and Knudson
    Mark P Little
    Department of Epidemiology and Public Health, Imperial College of Science, Technology and Medicine, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Int J Radiat Biol 78:49-68. 2002
  7. ncbi request reprint The bystander effect in C3H 10T cells and radon-induced lung cancer
    M P Little
    Department of Epidemiology and Public Health, Imperial College of Science, Technology and Medicine, St Mary s Campus, Norfolk Place, London W2 1PG, United Kingdom
    Radiat Res 156:695-9. 2001
  8. ncbi request reprint Comparison of the risks of cancer incidence and mortality following radiation therapy for benign and malignant disease with the cancer risks observed in the Japanese A-bomb survivors
    M P Little
    Department of Epidemiology and Public Health, Imperial College School of Medicine, Norfolk Place, London, UK
    Int J Radiat Biol 77:431-64. 2001
  9. ncbi request reprint Projection of cancer risks from the Japanese atomic bomb survivors to the England and Wales population taking into account uncertainty in risk parameters
    M P Little
    Department of Epidemiology and Public Health, Imperial College School of Medicine, London, UK
    Radiat Environ Biophys 39:241-52. 2000
  10. ncbi request reprint Absence of evidence for differences in the dose-response for cancer and non-cancer endpoints by acute injury status in the Japanese atomic-bomb survivors
    Mark P Little
    Department of Epidemiology and Public Health, Imperial College Faculty of Medicine, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Int J Radiat Biol 78:1001-10. 2002

Detail Information

Publications10

  1. ncbi request reprint A comparison of the degree of curvature in the cancer incidence dose-response in Japanese atomic bomb survivors with that in chromosome aberrations measured in vitro
    M P Little
    Department of Epidemiology and Public Health, Imperial College School of Medicine, St Mary s Campus, London, UK
    Int J Radiat Biol 76:1365-75. 2000
    ..To compare the degree of curvature in the dose-response for chromosome aberrations and for radiation-induced cancer...
  2. ncbi request reprint The bystander effect in experimental systems and compatibility with radon-induced lung cancer in humans
    M P Little
    Department of Epidemiology and Public Health, Imperial College of Science, Technology and Medicine, London, UK
    J Radiol Prot 22:A27-31. 2002
    ..Other experimental data relating to the bystander effect after alpha-particle exposure are surveyed; some of these data are more compatible with the epidemiological data...
  3. ncbi request reprint The proportion of thyroid cancers in the Japanese atomic bomb survivors associated with natural background radiation
    M P Little
    Department of Epidemiology and Public Health, Imperial College of Science, Technology and Medicine, London, UK
    J Radiol Prot 22:279-91. 2002
    ..5% for those over the age of 60, assuming that the absolute risk model applies. There is a similar increase in this percentage, if to a rather lower level (from 0.2 to 10.2%), assuming that the relative risk model applies...
  4. ncbi request reprint Cancer after exposure to radiation in the course of treatment for benign and malignant disease
    M P Little
    Department of Epidemiology and Public Health, Imperial College School of Medicine, London, UK
    Lancet Oncol 2:212-20. 2001
    ..This increase in risk has to be balanced against the generally high spontaneous cancer risk in these individuals and the benefits accruing from radiotherapy...
  5. ncbi request reprint Comparisons of lung tumour mortality risk in the Japanese A-bomb survivors and in the Colorado Plateau uranium miners: support for the ICRP lung model
    M P Little
    Department of Epidemiology and Public Health, Imperial College of Science, Technology and Medicine, St Mary s Campus, Norfolk Place, London, W2 1PG, UK
    Int J Radiat Biol 78:145-63. 2002
    ..To estimate the ratio of risks for exposure to radon progeny relative to low-LET radiation based on human lung cancer data, taking account of possible time and age variations in radiation-induced lung cancer risk...
  6. ncbi request reprint Modelling lung tumour risk in radon-exposed uranium miners using generalizations of the two-mutation model of Moolgavkar, Venzon and Knudson
    Mark P Little
    Department of Epidemiology and Public Health, Imperial College of Science, Technology and Medicine, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Int J Radiat Biol 78:49-68. 2002
    ..To model radon-induced lung cancer in uranium miners using a quasi-biological model of carcinogenesis...
  7. ncbi request reprint The bystander effect in C3H 10T cells and radon-induced lung cancer
    M P Little
    Department of Epidemiology and Public Health, Imperial College of Science, Technology and Medicine, St Mary s Campus, Norfolk Place, London W2 1PG, United Kingdom
    Radiat Res 156:695-9. 2001
    ..As a consequence, the bystander effect observed in the experimental C3H 10T(1/2) cell system probably does not play a large part in the process of radon-induced lung carcinogenesis in humans...
  8. ncbi request reprint Comparison of the risks of cancer incidence and mortality following radiation therapy for benign and malignant disease with the cancer risks observed in the Japanese A-bomb survivors
    M P Little
    Department of Epidemiology and Public Health, Imperial College School of Medicine, Norfolk Place, London, UK
    Int J Radiat Biol 77:431-64. 2001
    ....
  9. ncbi request reprint Projection of cancer risks from the Japanese atomic bomb survivors to the England and Wales population taking into account uncertainty in risk parameters
    M P Little
    Department of Epidemiology and Public Health, Imperial College School of Medicine, London, UK
    Radiat Environ Biophys 39:241-52. 2000
    ..Overall, cancer risks predicted by Bayesian Markov Chain Monte Carlo methods are similar to those derived by classical likelihood-based methods and which form the basis of established estimates of radiation-induced cancer risk...
  10. ncbi request reprint Absence of evidence for differences in the dose-response for cancer and non-cancer endpoints by acute injury status in the Japanese atomic-bomb survivors
    Mark P Little
    Department of Epidemiology and Public Health, Imperial College Faculty of Medicine, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Int J Radiat Biol 78:1001-10. 2002
    ..To ascertain possible evidence for radiosensitive subgroups in the Japanese atomic-bomb survivors...